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Aperçu des produits pour ADAM10 (ADAM10) Kits ELISA

Full name:
ADAM Metallopeptidase Domain 10 Kits ELISA (ADAM10)
Chez www.anticorps-enligne.fr sont 43 ADAM Metallopeptidase Domain 10 (ADAM10) Kits ELISA de 11 de différents fournisseurs disponibles. De plus, nous expédions ADAM10 Anticorps (142) et ADAM10 Protéines (20) et beaucoup plus de produits pour cette protéine. Un total de 209 ADAM10 produits sont actuellement listés.
Synonymes:
1700031C13Rik, ad10, ADAM-10, ADAM 10, Adam10, cd156c, HsT18717, kuz, kuzbanian, LOC100219653, madm, wu:fc03d12, xadam10

ADAM10 Kits ELISA mieux référencés

  1. Human ADAM10 Kit ELISA pour Sandwich ELISA - ABIN414771 : Van Crombruggen, Holtappels, De Ruyck, Derycke, Tomassen, Bachert: RAGE processing in chronic airway conditions: involvement of Staphylococcus aureus and ECP. dans The Journal of allergy and clinical immunology 2012 (PubMed)
    Show all 3 references for ABIN414771

Plus Kits ELISA pour ADAM10 partenaires d'interaction

Mouse (Murine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Thus, Leda-1/Pianp is constitutively processed by proprotein convertases, sheddases including MMPs and ADAM10/17 and intramembrane protease gamma-secretase.

  2. ADAM10 was dispensable for alpha-toxin (Montrer PLC Kits ELISA)-dependent xenophagic targeting of S. aureus, whereas a role for alpha-toxin (Montrer PLC Kits ELISA) attack on the plasma membrane was confirmed.

  3. ADAM10 was essentially involved in maxillofacial bone development. ADAM10 conditional knock-out KO mice present craniofacial dysmorphia and bone defects. Impaired osteoblast differentiation,proliferation and apoptosis underlie the bone deformity.

  4. Newborn mice deficient in ADAM10 exhibited organ-specific vascular defects.

  5. Findings demonstrate the direct requirement of ADAM10 in cortical radial migration and reveal the underlying mechanism by linking ADAM10-initiated regulated intramembrane proteolysis of Notch (Montrer NOTCH1 Kits ELISA) to the regulation of microtubule cytoskeleton through transcriptional control of Dcx (Montrer DCX Kits ELISA) expression

  6. our data afford the new insight that miR (Montrer MLXIP Kits ELISA)-103a inhibited abdominal aortic aneurysm (AAA (Montrer AAAS Kits ELISA)) growth via targeting ADAM10, which might be a promising therapeutic strategy to alleviate AAA (Montrer AAAS Kits ELISA).

  7. ADAM10 gene was predominantly expressed in the neurons of the cerebral cortex, hippocampus, thalamus and cerebellar granular cells in adult mouse CNS.

  8. Matrix metalloproteases ADAM10 and TACE (ADAM17) cleave AXL receptor tyrosine (Montrer AXL Kits ELISA)kinase (Axl) in lupus-prone leukocytes.

  9. Loss of ADAM10 in murine liver results in hepatocyte necrosis and concomitant liver fibrosis. ADAM10 directly regulates expression of bile acid transporters but is dispensable for Notch2 (Montrer NOTCH2 Kits ELISA)-dependent formation of the biliary system. Differentiation of liver progenitor cells to hepatocytes is augmented in the absence of ADAM10.

  10. Studies demonstrate a role for ADAM10 in the ectodomain shedding of LRP1 (Montrer LRP1 Kits ELISA) in the brain and the clearance of Abeta (Montrer APP Kits ELISA) across the blood-brain barrier, which may provide a novel strategy for attenuating Abeta (Montrer APP Kits ELISA) accumulation in the AD brain

Human ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. The overexpression of MTERF4 induced a significant increase in the levels of APP protein and secreted Abeta 42 in HEK293-APPswe cells compared with control cells these results suggest that MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10 in HEK293-APPswe cells; therefore, MTERF4 may play an important role in the pathogenesis of Alzheimer's disease.

  2. Pre-incubation with simvastatin prior to treatment with IL-1beta (Montrer IL1B Kits ELISA) + Oncostatin M (Montrer OSM Kits ELISA) decreased the level of CD44 (Montrer CD44 Kits ELISA) fragmentation, decreased the proportion of CD44 (Montrer CD44 Kits ELISA) that transits into the lipid raft fractions, decreased ADAM10 activity and diminished the interaction between CD44 (Montrer CD44 Kits ELISA) and ADAM10.

  3. ADAM17 (Montrer ADAM17 Kits ELISA) and ADAM10 cleave Nectin-4 (Montrer PVRL4 Kits ELISA) and release soluble Nectin-4 (Montrer PVRL4 Kits ELISA) (sN4).

  4. Data show that mononuclear leukocytes (PBMC) AXL receptor tyrosine kinase (Axl (Montrer AXL Kits ELISA)) is rescued by combined matrix metalloproteases ADAM10 and TACE (ADAM17 (Montrer ADAM17 Kits ELISA)) inhibition.

  5. we found that ADAM10 expression was associated with a more rapid metastatic progression confirming its role in uveal melanoma metastasis.

  6. the TLR4 (Montrer TLR4 Kits ELISA)/Gal-1 (Montrer LGALS1 Kits ELISA) signaling pathway regulates lactate-mediated EMT (Montrer ITK Kits ELISA) processes through the activation of ADAM10 and ADAM17 (Montrer ADAM17 Kits ELISA) in colon cancer cells.

  7. Studies demonstrate a role for ADAM10 in the ectodomain shedding of LRP1 (Montrer LRP1 Kits ELISA) in the brain and the clearance of Abeta (Montrer APP Kits ELISA) across the blood-brain barrier, which may provide a novel strategy for attenuating Abeta (Montrer APP Kits ELISA) accumulation in the AD brain

  8. In response to trastuzumab, both HER3 (Montrer ERBB3 Kits ELISA) and the metalloprotease (Montrer ADAM8 Kits ELISA) ADAM10 are simultaneously upregulated. The proteolytic activity of the latter then releases the HER3 (Montrer ERBB3 Kits ELISA) ligand heregulin (Montrer NRG1 Kits ELISA) from the cell surface to activate HER3 (Montrer ERBB3 Kits ELISA) and confer resistance to trastuzumab by inducing compensatory growth factor receptor (Montrer RYK Kits ELISA) signaling.

  9. Active ADAM10 promotes the carcinogenesis, invasion, metastasis and proliferation of ESCC and controls invasion and metastasis at least in part through the shedding of E-cadherin (Montrer CDH1 Kits ELISA) activity.

  10. We now show that ADAM10 is critical for alpha-hemolysin (Montrer PLC Kits ELISA)-mediated activation of the NLRP3 (Montrer NLRP3 Kits ELISA) inflammasome in human monocytes as siRNA knockdown or chemical blockade of ADAM10-alpha-hemolysin (Montrer PLC Kits ELISA) interaction leads to diminished inflammasome activation and cell death by reducing the available ADAM10 on the cell surface.

Xenopus laevis ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. A dramatic decline in ephrinB2 (Montrer EFNB2 Kits ELISA) protein levels on the absence of flotillin-1 (Montrer FLOT1 Kits ELISA) expression is specific, and is partly the result of an increased susceptibility to cleavage by the metalloprotease (Montrer ADAM8 Kits ELISA) ADAM10.

Pig (Porcine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. significantly increased expression of ADAM10 in the ISR versus non-ISR segment in diabetic minipigs

Cow (Bovine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Data show that ADAM10 and APLP2 (Montrer APLP2 Kits ELISA) are expressed in proximal tubule cells, and that ADAM10 activity has a pronounced effect on expression of specific brush-border proteins.

  2. Intracellular trafficking of ADAM10 critically requires a novel sorting signal within its cytoplasmic domain.

  3. N-glycosylation is crucial for ADAM10 processing and resistance to proteolysis, and results suggest that it is required for full-enzyme activity.

ADAM10 profil antigène

Antigen Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

Alternative names and synonyms associated with ADAM10

  • a disintegrin and metalloprotease domain 10a (adam10a) Elisa Kit
  • ADAM metallopeptidase domain 10 (ADAM10) Elisa Kit
  • ADAM metallopeptidase domain 10 (LOC100219653) Elisa Kit
  • ADAM metallopeptidase domain 10 (Adam10) Elisa Kit
  • a disintegrin and metallopeptidase domain 10 (Adam10) Elisa Kit
  • ADAM metallopeptidase domain 10 (adam10) Elisa Kit
  • ADAM10 (LOC100101614) Elisa Kit
  • 1700031C13Rik Elisa Kit
  • ad10 Elisa Kit
  • ADAM-10 Elisa Kit
  • ADAM 10 Elisa Kit
  • Adam10 Elisa Kit
  • cd156c Elisa Kit
  • HsT18717 Elisa Kit
  • kuz Elisa Kit
  • kuzbanian Elisa Kit
  • LOC100219653 Elisa Kit
  • madm Elisa Kit
  • wu:fc03d12 Elisa Kit
  • xadam10 Elisa Kit

Protein level used designations for ADAM10

a disintegrin and metalloprotease domain 10a , ADAM metallopeptidase domain 10 , disintegrin and metalloproteinase domain-containing protein 10 , ADAM10 metallopeptidase , disintegrin and metalloproteinase domain-containing protein 10-like , ADAM 10 , a disintegrin and metalloprotease domain (ADAM) 10 , a disintegrin and metalloprotease domain 10 , kuzbanian protein homolog , mammalian disintegrin-metalloprotease , CDw156 , a disintegrin and metalloproteinase domain 10 , metalloprotease/disintegrin , xKuz , a disintegrin and metallopeptidase domain 10 , disintegrin-metalloproteinase , myelin-associated metalloproteinase

GENE ID SPECIES
566044 Danio rerio
701355 Macaca mulatta
746942 Pan troglodytes
100068314 Equus caballus
100169741 Pongo abelii
100219653 Taeniopygia guttata
100313545 Saccoglossus kowalevskii
100476350 Ailuropoda melanoleuca
100606667 Nomascus leucogenys
11487 Mus musculus
102 Homo sapiens
399187 Xenopus laevis
29650 Rattus norvegicus
374113 Gallus gallus
478321 Canis lupus familiaris
397345 Sus scrofa
282132 Bos taurus
100718999 Cavia porcellus
100101614 Oryctolagus cuniculus
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