Aperçu des produits pour anti-ADAM17 (ADAM17) Anticorps

Full name:
anti-ADAM Metallopeptidase Domain 17 Anticorps (ADAM17)
Chez www.anticorps-enligne.fr sont 272 ADAM Metallopeptidase Domain 17 (ADAM17) Anticorps de 33 de différents fournisseurs disponibles. De plus, nous expédions ADAM17 Kits (34) et ADAM17 Protéines (17) et beaucoup plus de produits pour cette protéine. Un total de 332 ADAM17 produits sont actuellement listés.
Synonymes:
adam17, ADAM18, CD156B, CSVP, NISBD, si:dkey-81b15.2, Tace

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anti-ADAM17 Anticorps mieux référencés

  1. Human Monoclonal ADAM17 Primary Antibody pour FACS - ABIN4897862 : Kermarrec, Selloum, Plantefeve, Chosidow, Paoletti, Lopez, Mantz, Desmonts, Gougerot-Pocidalo, Chollet-Martin: Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage. dans Critical care medicine 2005 (PubMed)
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  2. Human Monoclonal ADAM17 Primary Antibody pour FACS - ABIN4897863 : Moreira-Tabaka, Peluso, Vonesch, Hentsch, Kessler, Reimund, Dumont, Muller: Unlike for human monocytes after LPS activation, release of TNF-α by THP-1 cells is produced by a TACE catalytically different from constitutive TACE. dans PLoS ONE 2012 (PubMed)
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  3. Human Polyclonal ADAM17 Primary Antibody pour ELISA, WB - ABIN1531481 : Bilousova, Taylor, Emirzian, Gylys, Frautschy, Cole, Teng: Parallel age-associated changes in brain and plasma neuronal pentraxin receptor levels in a transgenic APP/PS1 rat model of Alzheimer's disease. dans Neurobiology of disease 2015 (PubMed)
    Show all 3 references for 1531481

  4. Human Polyclonal ADAM17 Primary Antibody pour ELISA, WB - ABIN1536098 : Moss, Jin, Milla, Bickett, Burkhart, Carter, Chen, Clay, Didsbury, Hassler, Hoffman, Kost, Lambert, Leesnitzer, McCauley, McGeehan, Mitchell, Moyer, Pahel, Rocque, Overton, Schoenen, Seaton, Su et al.: Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha. ... dans Nature 1997 (PubMed)
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  5. Human Polyclonal ADAM17 Primary Antibody pour FACS, WB - ABIN388309 : Tellier, Canault, Poggi, Bonardo, Nicolay, Alessi, Nalbone, Peiretti: HDLs activate ADAM17-dependent shedding. dans Journal of cellular physiology 2007 (PubMed)
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  6. Human Polyclonal ADAM17 Primary Antibody pour EIA, WB - ABIN357025 : Takamune, Ikebe, Nagano, Shinohara: Involvement of NF-kappaB-mediated maturation of ADAM-17 in the invasion of oral squamous cell carcinoma. dans Biochemical and biophysical research communications 2007 (PubMed)
    Show all 2 references for 357025

  7. Human Polyclonal ADAM17 Primary Antibody pour ELISA, WB - ABIN184721 : Black, Rauch, Kozlosky, Peschon, Slack, Wolfson, Castner, Stocking, Reddy, Srinivasan, Nelson, Boiani, Schooley, Gerhart, Davis, Fitzner, Johnson, Paxton, March, Cerretti: A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. dans Nature 1997 (PubMed)

  8. Human Polyclonal ADAM17 Primary Antibody pour FACS, IF (p) - ABIN705671 : Li, Xie, He, Wang, Duan, Yang, Wang: Identification of ADAM10 and ADAM17 with potential roles in the spermatogenesis of the Chinese mitten crab, Eriocheir sinensis. dans Gene 2015 (PubMed)

Plus d’anticorps contre ADAM17 partenaires d’interaction

Mouse (Murine) ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. Conditional ADAM17 knockout mice lacking ADAM17 in all leukocytes had a significant survival advantage during severe polymicrobial sepsis induced by CLP, associated with enhanced neutrophil recruitment at the infectious locus along with decreased bacterial spread and circulating levels of proinflammatory factors. Its induction during sepsis may tip the balance between efficient and impaired neutrophil recruitment.

  2. These results demonstrate a novel physiologic role for a disintegrin and metalloprotease 17 in regulating murine IL-6 (Montrer IL6 Anticorps) signals during inflammatory processes.

  3. These results show that TACE is a target of, and is downregulated by, soluble TNF (Montrer TNF Anticorps)-induced AP-2alpha (Montrer TFAP2A Anticorps) transcription factor in dendritic cells

  4. the critical role of the transmembrane domains of ADAM17 and Rhbdf2 (Montrer RHBDF2 Anticorps) in the regulation of the ADAM17 and EGFR (Montrer EGFR Anticorps), and ADAM17 and TNFalpha (Montrer TNF Anticorps) signaling pathways, was examined.

  5. Findings provide evidence that ADAM10 (Montrer ADAM10 Anticorps), and not ADAM17, is indispensable for proper retinal development as a regulator of NOTCH (Montrer NOTCH1 Anticorps) signaling.

  6. this study shows that the iRhom2 (Montrer RHBDF2 Anticorps)/ADAM17 pathway plays an important role in regulating CSF1R (Montrer CSF1R Anticorps) expression in the myeloid cell compartment at steady state, and in modulating development of monocytes/macrophages during their repopulation

  7. Suggest an atheroprotective role of ADAM17, which might be mediated by cleaving membrane-bound TNFalpha (Montrer TNF Anticorps) and TNFR2 (Montrer TNFRSF1B Anticorps), thereby preventing overactivation of endogenous TNFR2 (Montrer TNFRSF1B Anticorps) signaling in cells of the vasculature.

  8. Aging and obesity cooperatively reduce caveolin-1 (Montrer CAV1 Anticorps) expression and increase vascular endothelial ADAM17 activity and soluble TNF (Montrer TNF Anticorps) release in adipose tissue, which may contribute to the development of remote coronary microvascular dysfunction in older obese patients.

  9. Thus, Leda-1/Pianp (Montrer C12orf53 Anticorps) is constitutively processed by proprotein convertases, sheddases including MMPs and ADAM10 (Montrer ADAM10 Anticorps)/17 and intramembrane protease gamma-secretase.

  10. Matrix metalloproteases ADAM10 and TACE (ADAM17) cleave AXL receptor tyrosine (Montrer AXL Anticorps)kinase (Axl) in lupus-prone leukocytes.

Human ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. TNF-alpha-converting enzyme -mediated cleavage of soluble RANKL (Montrer TNFSF11 Anticorps) from activated lymphocytes, especially B cells, can promote osteoclastogenesis in periodontitis.

  2. Cell stimulation can downregulate expression of mature ADAM17 from the cell surface and induce release of exosomal ADAM17, which can then distribute and contribute to substrate shedding on more distant cells.

  3. Aging and obesity cooperatively reduce caveolin-1 (Montrer CAV1 Anticorps) expression and increase vascular endothelial ADAM17 activity and soluble TNF (Montrer TNF Anticorps) release in adipose tissue, which may contribute to the development of remote coronary microvascular dysfunction in older obese patients.

  4. Our data demonstrated that elevated serum Semaphorin5A (Sema5A (Montrer SEMA5A Anticorps)) in SLE patients correlated with disease activity and are involved in kidney and blood system damage; ADAM17 might be involved in the release of secreted Sema5A (Montrer SEMA5A Anticorps).

  5. ADAM17 and ADAM10 (Montrer ADAM10 Anticorps) cleave Nectin-4 (Montrer PVRL4 Anticorps) and release soluble Nectin-4 (Montrer PVRL4 Anticorps) (sN4).

  6. ADAM17 promotes epithelial-mesenchymal transition via the TGF-beta (Montrer TGFB1 Anticorps)/Smad (Montrer SMAD1 Anticorps) pathway. the present study demonstrates that ADAM17 plays a critical role in the development of gastric cancer and provides a potential therapeutic target for gastric cancer.

  7. FHL2 (Montrer FHL2 Anticorps) interacts with ADAM-17 in normal, dysplastic and malignant colon epithelial cells. Colocalisation of these proteins is more frequent in malignant than in normal and dysplastic cells, suggesting a role for ADAM-17/FHL2 (Montrer FHL2 Anticorps) complex in the development of colorectal cancer.

  8. The present study suggests that ADAM17-siRNA inhibits MCF-7 breast cancer and is activated through the EGFR (Montrer EGFR Anticorps)-PI3K (Montrer PIK3CA Anticorps)-AKT (Montrer AKT1 Anticorps) signaling pathway

  9. Data show that mononuclear leukocytes (PBMC) AXL receptor tyrosine kinase (Axl (Montrer AXL Anticorps)) is rescued by combined matrix metalloproteases ADAM10 (Montrer ADAM10 Anticorps) and TACE (ADAM17) inhibition.

  10. the TLR4 (Montrer TLR4 Anticorps)/Gal-1 (Montrer LGALS1 Anticorps) signaling pathway regulates lactate-mediated EMT (Montrer ITK Anticorps) processes through the activation of ADAM10 (Montrer ADAM10 Anticorps) and ADAM17 in colon cancer cells.

Pig (Porcine) ADAM Metallopeptidase Domain 17 (ADAM17) interaction partners

  1. ADAM17 was involved in porcine CD16 (Montrer CD16 Anticorps) shedding in porcine reproductive and respiratory syndrome virus-infected pigs.

  2. Overexpression of ADAM17 induced downregulation of CD163 (Montrer CD163 Anticorps) expression and a reduction in reproductive and respiratory syndrome virus infection.

  3. activation of TACE/ADAM17 via a PKC (Montrer FYN Anticorps)-induced c-Src (Montrer SRC Anticorps)-dependent manner mediates proteolytic activation of the EGF (Montrer EGF Anticorps)-like factors that are involved in the induction of granulosa cell differentiation, cumulus expansion, and meiotic maturation of porcine oocytes

  4. Data indicate that TNF-alpha (Montrer TNF Anticorps) stimulates Rac (Montrer AKT1 Anticorps), ADAM17/TACE, and RhoA (Montrer RHOA Anticorps) through the guanine nucleotide exchange factor (Montrer ARHGEF12 Anticorps) (GEF)-H1 (Montrer ARHGEF2 Anticorps).

  5. progesterone-induced TACE/ADAM17 leads to production of soluble EGF (Montrer EGF Anticorps) domain from cumulus cells, which enhances functional changes of cumulus cells and progresses meiotic maturation of oocytes

ADAM17 profil antigène

Antigen Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme\; binds mitotic arrest deficient 2 protein\; and also plays a prominent role in the activation of the Notch signaling pathway.

Alternative names and synonyms associated with ADAM17

  • ADAM metallopeptidase domain 17 (ADAM17) anticorps
  • a disintegrin and metallopeptidase domain 17b (adam17b) anticorps
  • ADAM metallopeptidase domain 17 (adam17) anticorps
  • a disintegrin and metallopeptidase domain 17 (Adam17) anticorps
  • ADAM metallopeptidase domain 17 (Adam17) anticorps
  • adam17 anticorps
  • ADAM18 anticorps
  • CD156B anticorps
  • CSVP anticorps
  • NISBD anticorps
  • si:dkey-81b15.2 anticorps
  • Tace anticorps

Protein level used designations for ADAM17

ADAM metallopeptidase domain 17 (tumor necrosis factor, alpha, converting enzyme) , a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme) , disintegrin and metalloproteinase domain-containing protein 17 , tumor necrosis factor alpha converting enzyme , a disintegrin and metallopeptidase domain 17 , ADAM metallopeptidase domain 17 , a disintegrin and metalloprotease domain 17 , disintegrin metalloproteinase , disintegrin and metalloproteinase domain-containing protein 17-like , ADAM 17 , TNF-alpha convertase , TNF-alpha converting enzyme , TNF-alpha-converting enzyme , a disintegrin and metalloprotease domain 17; TNF-alpha converting enzyme , a disintegrin and metalloproteinase domain 17 , ADAM metallopeptidase domain 18 , snake venom-like protease , tumor necrosis factor, alpha, converting enzyme

GENE ID SPECIES
421931 Gallus gallus
459018 Pan troglodytes
560657 Danio rerio
694429 Macaca mulatta
733430 Xenopus laevis
100072496 Equus caballus
100406520 Callithrix jacchus
100482770 Ailuropoda melanoleuca
11491 Mus musculus
6868 Homo sapiens
57027 Rattus norvegicus
475662 Canis lupus familiaris
397343 Sus scrofa
517541 Bos taurus
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