Aperçu des produits pour anti-NCOR2 (NCOR2) Anticorps

Full name:
anti-Nuclear Receptor Corepressor 2 Anticorps (NCOR2)
Chez www.anticorps-enligne.fr sont 12 Nuclear Receptor Corepressor 2 (NCOR2) Anticorps de 3 de différents fournisseurs disponibles. Un total de 12 NCOR2 produits sont actuellement listés.
Synonymes:
CTG26, gb:be017685, N-CoR, N-CoR2, NCOR2, si:bz71m17.2, SMAP270, smrt, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1
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NCOR2 20602 Q9WU42
NCOR2 9612 Q9Y618
NCOR2    

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Plus d’anticorps contre NCOR2 partenaires d’interaction

Zebrafish Nuclear Receptor Corepressor 2 (NCOR2) interaction partners

  1. Ncor1 (Montrer NCOR1 Anticorps) and Ncor2 play essential but distinct roles in zebrafish primitive myelopoiesis

  2. A novel regulatory mechanism for Ncor2 through Fos-Vegfd-Notch signaling cascade during hematopoietic stem cell development in zebrafish embryos.

  3. rar-ncor2 corepressor complex may be part of an embryonic, epigenetic switch that keeps retinoic acid responsive genes off before retinoic becomes available to the embryo

Mouse (Murine) Nuclear Receptor Corepressor 2 (NCOR2) interaction partners

  1. Both the acetylation and SUMOylation status of the PXR (Montrer NR1I2 Anticorps) protein is affected by its ability to associate with the lysine de-acetylating enzyme HDAC3 (Montrer HDAC3 Anticorps) in a complex with SMRT.

  2. These studies support a model in which NCOR1 (Montrer NCOR1 Anticorps)/2 mediates direct Retinoic acid-dependent repression of Fgf8 (Montrer FGF8 Anticorps) in caudal (Montrer CAD Anticorps) progenitors in order to control somitogenesis.

  3. demonstrate that the binding of HDAC3 (Montrer HDAC3 Anticorps) to IR nGREs in vivo is mediated through interaction with SMRT/NCoR1 (Montrer NCOR1 Anticorps)

  4. GR SUMOylation site is mandatory for the formation of a GR-small ubiquitin-related modifiers (SUMOs)-SMRT/NCoR1 (Montrer NCOR1 Anticorps)-HDAC3 (Montrer HDAC3 Anticorps) repressing complex, which is indispensable for NF-kappaB (Montrer NFKB1 Anticorps)/AP1 (Montrer JUN Anticorps)-mediated GC-induced tethered indirect transrepression in vitro

  5. changes in dietary components can consistently, if moderately, modulate the total transcript levels and the mRNA splicing of NCoR (Montrer NCOR1 Anticorps) and SMRT in both cultured cells and intact mice.

  6. SMRT regulates glucocorticoid action in adipocytes.

  7. While silencing mediator of retinoid and thyroid hormone receptor (Montrer THRA Anticorps) played little role in TH-regulated pathways, when disrupted in combination with nuclear receptor corepressor, it greatly accentuated the synthesis and storage of hepatic lipid

  8. HDAC3 (Montrer HDAC3 Anticorps) enzyme activity is undetectable in mice bearing point mutations in the deacetylase-activating domain of both NCOR1 (Montrer NCOR1 Anticorps) and SMRT.

  9. These results reveal that Bcl6 (Montrer BCL6 Anticorps)-SMRT/NCoR (Montrer NCOR1 Anticorps) complexes constrain immune responses and contribute to the prevention of atherosclerosis.

  10. SMRT is an adipogenic gatekeeper as it directly fine-tunes transcription of pro- and antiadipogenic genes.

Human Nuclear Receptor Corepressor 2 (NCOR2) interaction partners

  1. The mechanism of IL-6 (Montrer IL6 Anticorps)-induced AR activation is mediated through enhancing AR-SRC-1 (Montrer SRC Anticorps) interaction and inhibiting AR-SMRT interaction.

  2. IL-6 (Montrer IL6 Anticorps)-mediated AR antagonism induced by cypermethrin is related to repress the recruitment of co-regulators SRC-1 (Montrer SRC Anticorps) and SMRT to the AR in a ligand-independent manner

  3. this study identifies NCOR2 as a new gene for FVC, indicating the importance of further research into the role of vitamin A intake/supplementation and its interactions with related genes in the regulation of FVC.

  4. Molecular basis for the specific interactions between HDAC4 (Montrer HDAC4 Anticorps) and the SMRT corepressor.

  5. SNPs in Notch (Montrer NOTCH1 Anticorps) pathway genes may be predictors of cutaneous melanoma disease-specific survival.

  6. Significant methylation changes in the SLC23A2 (Montrer SLC23A2 Anticorps) and NCOR2 regulatory regions.

  7. A repeated peptide motif present in both SMRT and NCoR is sufficient to mediate specific interaction, with micromolar affinity, with all the Class IIa Histone Deacetylases (HDACs 4, 5, 7, and 9).

  8. SMRT enhances cell growth of estrogen receptor-alpha (Montrer ESR1 Anticorps)-positive breast cancer cells by promotion of cell cycle progression and inhibition of apoptosis.

  9. Phosphorylation of the CK2 (Montrer CSNK2A1 Anticorps) site on SMRT significantly increased affinity for SHARP.

  10. model where p53 (Montrer TP53 Anticorps) binding to the SMRT deacetylase activation domain (DAD) limits HDAC3 (Montrer HDAC3 Anticorps) interaction with this coregulator, thereby facilitating SMRT coactivation of p53 (Montrer TP53 Anticorps)-dependent gene expression

NCOR2 profil antigène

Antigen Summary

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with NCOR2

  • similar to nuclear receptor co-repressor 2 (NCOR2) anticorps
  • nuclear receptor co-repressor 2 (ncor2) anticorps
  • nuclear receptor corepressor 2 (NCOR2) anticorps
  • nuclear receptor corepressor 2 (ncor2) anticorps
  • nuclear receptor co-repressor 2 (NCOR2) anticorps
  • nuclear receptor co-repressor 2 (Ncor2) anticorps
  • CTG26 anticorps
  • gb:be017685 anticorps
  • N-CoR anticorps
  • N-CoR2 anticorps
  • NCOR2 anticorps
  • si:bz71m17.2 anticorps
  • SMAP270 anticorps
  • smrt anticorps
  • SMRTE anticorps
  • SMRTE-tau anticorps
  • TNRC14 anticorps
  • TRAC anticorps
  • TRAC-1 anticorps
  • TRAC1 anticorps

Protein level used designations for NCOR2

nuclear receptor corepressor 2 , silencing mediator , thyroid hormone receptor , nuclear receptor co-repressor 2 , N-CoR2 , T3 receptor-associating factor , TRAC , silencing mediator of retinoic acid and thyroid hormone receptor , silencing mediator of retinoid acid and thyroid hormone receptor , thyroid-, retinoic-acid-receptor-associated corepressor , CTG repeat protein 26 , silencing mediator for retinoid and thyroid hormone receptors

GENE ID SPECIES
467150 Pan troglodytes
561503 Danio rerio
706261 Macaca mulatta
733898 Xenopus (Silurana) tropicalis
100059253 Equus caballus
100337057 Bos taurus
100581656 Nomascus leucogenys
20602 Mus musculus
9612 Homo sapiens
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