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Aperçu des produits pour GTPase NRas (NRAS) Kits ELISA

Full name:
GTPase NRas Kits ELISA (NRAS)
Chez www.anticorps-enligne.fr sont 6 GTPase NRas (NRAS) Kits ELISA de 2 de différents fournisseurs disponibles. De plus, nous expédions GTPase NRas Anticorps (99) et GTPase NRas Protéines (17) et beaucoup plus de produits pour cette protéine. Un total de 127 GTPase NRas produits sont actuellement listés.
Synonymes:
ALPS4, AV095280, fj99a10, H-RAS, HRAS, N-RAS, NRAS, NRAS1, NS6, wu:fj99a10, zgc:100761, zras-b1

Plus Kits ELISA pour GTPase NRas partenaires d'interaction

Mouse (Murine) GTPase NRas (NRAS) interaction partners

  1. loss of one allele of Hras (Montrer HRAS Kits ELISA) increased the sensitivity of mice to this carcinogen, and this effect was further exacerbated by the loss of the second Hras (Montrer HRAS Kits ELISA) allele. However, loss of one or both alleles of Nras failed to alter tumor burden, either in the absence or presence of Hras (Montrer HRAS Kits ELISA), after exposure to urethane.

  2. Genetic inactivation of Ezh2 (Montrer EZH2 Kits ELISA) or Eed (Montrer EED Kits ELISA) cooperates with NRASQ61K in leukemogenesis.

  3. Data indicate that S-phase kinase-associated protein 2 (SKP2) cooperates with N-Ras and AKT proto-oncogenes to promote hepatocarcinogenesis in vivo.

  4. Activated NRAS and aberrant Wnt (Montrer WNT2 Kits ELISA) signaling conspire to drive congenital melanocytic nevus syndrome.

  5. a crucial role of RXRa in suppression of UVB-induced melanomas in the context of driver mutations such as activated CDK4(R24C/R24C) or oncogenic NRAS(Q61K) and altered expression of p53 and PTEN

  6. This work explains the curious predominance in human melanoma of mutations of codon 61 of NRAS over other oncogenic NRAS mutations. we show that physiologic expression of NRASQ61R, but not NRASG12D, drives melanoma formation.

  7. These data reveal the L. major-enhanced CD40-induced N-Ras activation as a novel immune evasion strategy and the potential for Ras isoform-targeted antileishmanial immunotherapy and immunoprophylaxis.

  8. NRAS expression is required for the proliferative advantage of human AML (Montrer RUNX1 Kits ELISA) cell lines in vitro and for the maintenance of mouse Nras-mutant AML (Montrer RUNX1 Kits ELISA) in vivo

  9. There was a nearly complete correspondence between the signaling pathways that were regulated by N-ras in immune cell types.

  10. Cbfbeta (Montrer CBFB Kits ELISA)-SMMHC (Montrer MYH11 Kits ELISA) and Nras(G12D) promote the survival of preleukemic myeloid progenitors primed for leukemia by activation of the MEK (Montrer MDK Kits ELISA)/ERK (Montrer EPHB2 Kits ELISA)/Bim (Montrer BCL2L11 Kits ELISA) axis, and define Nras(LSL-G12D); Cbfb (Montrer CBFB Kits ELISA)(56M) mice as a valuable genetic model for the study of AML (Montrer RUNX1 Kits ELISA) therapies.

Human GTPase NRas (NRAS) interaction partners

  1. The data revealed the presence of a partial tandem duplication of the MLL (Montrer MLL Kits ELISA) gene as the only detectable copy number change and 11 non-silent somatic mutations, including DNMT3A (Montrer DNMT3A Kits ELISA) R882H and NRAS G13D. All somatic lesions were present both at initial MDS (Montrer PAFAH1B1 Kits ELISA)/MPN (Montrer PRSS27 Kits ELISA)-U diagnosis and at AML (Montrer RUNX1 Kits ELISA) presentation at similar mutant allele frequencies.

  2. NRAS mutation is associated with CNS melanoma.

  3. NRAS mutation is associated with melanoma.

  4. Silencing VPS35 (Montrer vps35 Kits ELISA) increased N-Ras's association with cytoplasmic vesicles, diminished GTP (Montrer AK3 Kits ELISA) loading of Ras, and inhibited mitogen-activated protein kinase (Montrer MAPK1 Kits ELISA) signaling and growth of N-Ras-dependent melanoma cells.

  5. By using this model of curative-intent, margin-negative resection in patients at high risk of recurrence, the authors were able to establish a link between mutation location within the K/NRAS gene and the biology of metastatic colorectal cancer.

  6. review focuses on the genes, which are frequently mutated in various cancers and are known to be important in the advance and progression of colorectal cancer and melanoma, namely KRAS, NRAS and BRAF (Montrer BRAF Kits ELISA)

  7. Report KRAS, NRAS, PIK3CA, and BRAF mutational profile in poorly differentiated clusters of KRAS-mutated colon cancer may depend on tumor histology.

  8. SP174 immunohistochemistry allows sensitive detection of NRAS and KRAS Q61R mutants.

  9. multiregion analysis was performed in 60 spatially separated tumor areas according to the pathological tumor node metastasis (pTNM) staging and KRAS, NRAS and BRAF mutations were tested using pyrosequencing.these results suggest the need for multiple RAS testing in different parts of the same tumor and/or more sensitive techniques.

  10. that the presence of NRAS, PTEN and AKT1 (Montrer AKT1 Kits ELISA) gene mutations may have an influence on the occurrence of CNS metastases in patients with SqCC

Zebrafish GTPase NRas (NRAS) interaction partners

  1. Although oncogenic NRAS expression alone was found to be insufficient to promote tumor formation, loss of functional p53 (Montrer TP53 Kits ELISA) was found to collaborate with NRAS expression in the genesis of melanoma.

GTPase NRas (NRAS) profil antigène

Antigen Summary

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.

Alternative names and synonyms associated with GTPase NRas (NRAS)

  • GTPase NRas (Tsp_01117) Elisa Kit
  • African clawed frog N-ras (n-ras) Elisa Kit
  • neuroblastoma ras oncogene (Nras) Elisa Kit
  • neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) Elisa Kit
  • neuroblastoma RAS viral (v-ras) oncogene homolog (nras) Elisa Kit
  • ALPS4 Elisa Kit
  • AV095280 Elisa Kit
  • fj99a10 Elisa Kit
  • H-RAS Elisa Kit
  • HRAS Elisa Kit
  • N-RAS Elisa Kit
  • NRAS Elisa Kit
  • NRAS1 Elisa Kit
  • NS6 Elisa Kit
  • wu:fj99a10 Elisa Kit
  • zgc:100761 Elisa Kit
  • zras-b1 Elisa Kit

Protein level used designations for GTPase NRas (NRAS) Kits ELISA

GTPase NRas , transforming protein N-Ras , neuroblastoma RAS viral (v-ras) oncogene homolog , N-ras oncogene , p21 protein , N-ras protein part 4 , v-ras neuroblastoma RAS viral oncogene homolog , ras p21 , N-ras oncogene p21 , etID18709.8 , neuroblastoma RAS viral oncogene-like protein , neuroblastoma ras oncogene , v-Ha-ras Harvey rat sarcoma viral oncogene homolog

GENE ID SPECIES
10905151 Trichinella spiralis
399446 Xenopus laevis
24605 Rattus norvegicus
18176 Mus musculus
100135584 Cavia porcellus
4893 Homo sapiens
403872 Canis lupus familiaris
30380 Danio rerio
419885 Gallus gallus
100739349 Sus scrofa
506322 Bos taurus
100174317 Pongo abelii
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