Aperçu des produits pour anti-p53 (TP53) Anticorps

Full name:
anti-Tumor Protein P53 Anticorps (TP53)
Chez www.anticorps-enligne.fr sont 2452 Tumor Protein P53 (TP53) Anticorps de 51 de différents fournisseurs disponibles. De plus, nous expédions p53 Kits (143) et p53 Protéines (84) et beaucoup plus de produits pour cette protéine. Un total de 2844 p53 produits sont actuellement listés.
Synonymes:
bbl, BCC7, bfy, bhy, brp53, drp53, etID22686.5, fb40d06, LFS1, p44, P53, Tp53, TpMs, Trp53, wu:fb40d06, Xp53, zgc:111919
afficher tous les anticorps Gène GeneID UniProt
TP53 22059 P02340
TP53 84260 Q9BT92
Anti-Rat TP53 TP53 24842 P10361

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Tous anti-p53 Anticorps disponible

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anti-p53 Anticorps mieux référencés

  1. Human Monoclonal p53 Primary Antibody pour IHC (f), IHC (fro) - ABIN967416 : Cheng, Yee, Yeargin, Friedmann, Haas: Suppression of acute lymphoblastic leukemia by the human wild-type p53 gene. dans Cancer research 1992 (PubMed)
    Show all 11 references for 967416

  2. Human Polyclonal p53 Primary Antibody pour IF, IHC (p) - ABIN390204 : Blanchette, Cheng, Yan, Ketner, Ornelles, Dobner, Conaway, Conaway, Branton: Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53. dans Molecular and cellular biology 2004 (PubMed)
    Show all 4 references for 390204

  3. Human Monoclonal p53 Primary Antibody pour IHC (fro), IF - ABIN1108553 : Isobe, Emanuel, Givol, Oren, Croce: Localization of gene for human p53 tumour antigen to band 17p13. dans Nature 1986 (PubMed)
    Show all 2 references for 1108553

  4. Horse (Equine) Polyclonal p53 Primary Antibody pour IHC, WB - ABIN2792141 : Zakut-Houri, Bienz-Tadmor, Givol, Oren: Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells. dans The EMBO journal 1985 (PubMed)

  5. Cow (Bovine) Polyclonal p53 Primary Antibody pour WB - ABIN2779979 : Rotter, Wolf, Pravtcheva, Ruddle: Chromosomal assignment of the murine gene encoding the transformation-related protein p53. dans Molecular and cellular biology 1984 (PubMed)

  6. Human Polyclonal p53 Primary Antibody pour ChIP, ELISA - ABIN2779319 : Boehme, Kulikov, Blattner: p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK. dans Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

Plus d’anticorps contre p53 partenaires d’interaction

Mouse (Murine) Tumor Protein P53 (TP53) interaction partners

  1. Key features of genome recognition by p53 and unprecedented insight into the pathways associated with p53 reactivation and tumour regression, paving the way for their therapeutic application.

  2. work reveals that simulated microgravity promotes the apoptotic response through a combined modulation of the Uev1A/TICAM/TRAF (Montrer TRAF1 Anticorps)/NF-kappaB (Montrer NFKB1 Anticorps)-regulated apoptosis and the p53/PCNA (Montrer PCNA Anticorps)- and ATM (Montrer ATM Anticorps)/ATR (Montrer ATR Anticorps)-Chk1 (Montrer CHEK1 Anticorps)/2-controlled DNA-damage response pathways.

  3. The TP53 knockout shifted the phenotypes of A549 cells induced by ALKBH3 (Montrer ALKBH3 Anticorps) knockdown from cell cycle arrest to apoptosis induction, suggesting that the TP53 gene status is a critical determinant of the phenotypes induced by ALKBH3 (Montrer ALKBH3 Anticorps) knockdown in NSCLC cells.

  4. Our study demonstrates that unlike conventional tumoricidal therapies, which rely on effective p53 targeting in each tumor cell and often associate with systemic toxicity, this immune-based strategy requires only limited local p53 activation to alter the immune landscape of TME and subsequently amplify immune response to systemic antitumor immunity

  5. median survival of KPIC mice was longer than that of LSL-KrasG12D; Ink4flox/flox; Ptf1/p48 (Montrer PTF1A Anticorps)-Cre mice (KIC) (89 vs 62 days) and shorter than that of KRAS (KrasG12D), TP53 (Trp53R172H/+) and Ptf1/p48 (Montrer PTF1A Anticorps)-Cre (KPC) mice

  6. Combined deletion of Vhl (Montrer VHL Anticorps), Trp53 and Rb1 (Montrer RB1 Anticorps) specifically in renal epithelial cells in mice caused clear cell renal cell carcinoma (Montrer MOK Anticorps).

  7. Data show that Emu-Myc (Montrer MYC Anticorps) mice lacking both p21 (Montrer D4S234E Anticorps) and PUMA (Montrer BBC3 Anticorps) developed lymphoma at a rate considerably longer latency than Emu-Myc (Montrer MYC Anticorps);p53(+/-)mice.

  8. The loss of p53 function is a requirement for the formation of giant spermatogonia (GSG) whereas DNA damage acts as a promoting trigger. The formation of GSG does not translate to higher efficacy of testicular tumorigenesis arising from mutant p53 cells, which might be due to the presence of delayed-onset of p53-independent apoptosis.

  9. p21 (Montrer D4S234E Anticorps)-associated inhibition of early-stage malignant progression and the intense expression in papilloma outgrowths, identifies a novel, significant antagonism between p21 (Montrer D4S234E Anticorps) and ras(Ha)/ROCK2 (Montrer ROCK2 Anticorps)/NF-kappaB (Montrer NFKB1 Anticorps) signalling in skin carcinogenesis.these data show that ROCK2 (Montrer ROCK2 Anticorps) activation induces malignancy in ras(Ha)-initiated/promoted papillomas in the context of p53 loss and novel NF-kappaB (Montrer NFKB1 Anticorps) expression

  10. TP53 mutation is associated with Triple-Negative Breast Cancer.

Human Tumor Protein P53 (TP53) interaction partners

  1. Data establish the DLX3 (Montrer DLX3 Anticorps)-p53 interplay as a major regulatory axis in epidermal differentiation and suggest that DLX3 (Montrer DLX3 Anticorps) is a modulator of skin carcinogenesis.

  2. Data show that Prima-1 kills hypoxic wt p53 KRAS-mutant cells resistant to 3-bromopyruvate (3-BrPA), partly by decreasing GLUT-1 (Montrer SLC2A1 Anticorps) expression.

  3. Results indicate that the induction of long non-coding RNA NEAT1 expression contributes to the tumor-suppressor function of p53 and suggest that p53 and NEAT1 constitute a transcriptional network contributing to various biological functions and tumor suppression.

  4. HULC activates p53-p21 (Montrer CDKN1A Anticorps) pathway and promotes nasopharyngeal carcinoma cell growth.

  5. Mutations in TP53 and STK11 (Montrer STK11 Anticorps) also impacted tumor biology regardless of KRAS status, with TP53 strongly associated with enhanced proliferation and STK11 (Montrer STK11 Anticorps) with suppression of immune surveillance.

  6. Sp100A exhibits tumor-suppressive activity, not only by stabilizing p53 transactivation but also by depressing E1A (Montrer BCKDHA Anticorps)/E1B (Montrer BCKDHB Anticorps)-55K-mediated transformation.

  7. Here we present, as far as we are aware, the first case of metastatic microcystic adnexal carcinoma with DNA sequencing results indicating a mutation in TP53 and chromosomal losses in cyclin dependent kinase inhibitor 2A (CDKN2A (Montrer CDKN2A Anticorps)) and cyclin dependent kinase inhibitor 2B (CDKN2B (Montrer CDKN2B Anticorps)).

  8. This case contradicts previous reports of p53 and BRAF (Montrer BRAF Anticorps) mutations portending worsened tumor behavior and prognosis and demonstrates that further studies are needed to delineate the role of genetic characterization in the biologic understanding and management of gangliogliomas.

  9. This work highlights the importance of the p53-miR-191-SOX4 axis in the regulation of apoptosis and doxorubicin resistance in breast cancer cell lines (MCF7 and ZR-75)

  10. Results indicate that it is possible to detect mutated p53 genes with the circulating DNA (cirDNA) and that this could be used as a biomarker of tumor recurrence during the clinical evolution of the transplanted patients.

Pig (Porcine) Tumor Protein P53 (TP53) interaction partners

  1. This study demonstrated that various expression levels of p53 in porcine fibroblasts could be achieved by gene targeting and RNA interference.

  2. SIRT1 (Montrer SIRT1 Anticorps), p53 and NF-kappaB (Montrer NFKB1 Anticorps) are involved in the control of both the proliferation and the apoptosis of ovarian cells.

  3. Taken together,these results demonstrated that Porcine parvovirus infection induced apoptosis in PK-15 cells through activation of p53 and mitochondria-mediated apoptosis pathway.

  4. Data indicate that higher hepatic glucocorticoid receptor (GR (Montrer NR3C1 Anticorps)) expression in EHL piglets attributes mainly to the enhanced transcription of GR promoter 1-9/10 from breed-specific interaction of p53 and specificity protein 1 (Sp1 (Montrer SP1 Anticorps)).

  5. Taken together, these results demonstrated that transmissible gastroenteritis virus infection promoted the activation of p38 MAPK (Montrer MAPK14 Anticorps) and p53 signalling, and p53 signalling might play a dominant role in the regulation of cell apoptosis.

  6. role of transcription factor p53 and the metabolic hormone leptin (Montrer LEP Anticorps), in controlling basic functions (proliferation, apoptosis and secretory activity) of ovarian cells

  7. differential expression of p53 pathway-related genes accounts for breed-specific skeletal muscle and meat characteristics

  8. CONCLUSION(S): (1) Apoptosis is involved in follicular atresia; (2) Bcl-2 (Montrer BCL2 Anticorps) is induced by warm ischemia; and (3) cryopreservation insult does not alter the apoptotic signals with short tissue preparation time.

  9. Suppressive effect of FSH (Montrer BRD2 Anticorps) and LH on p53 expression and caspase-3 (Montrer CASP3 Anticorps) activity with parallel increase in bcl-2 (Montrer BCL2 Anticorps) expression and increased P production was observed.

  10. p53 signaling might be a major determinant for the replicative senescence in the miniature pig fibroblast cells that have the shorter lifespan and slower growth rate compared to primary domestic pig fibroblast cells in vitro.

Rabbit Tumor Protein P53 (TP53) interaction partners

  1. Suppressing expression of p53 was a required event in two assays of proliferative vitreoretinopathy.

  2. These results suggest that p38 MAPK (Montrer MAPK14 Anticorps) signal transduction pathway is critical to NO-induced chondrocyte apoptosis, and p38 (Montrer MAPK14 Anticorps) plays a role by way of stimulating NF-kappaB (Montrer NFKB1 Anticorps), p53 and caspase-3 (Montrer CASP3 Anticorps) activation.

  3. Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 and decrease in the antiapoptotic BCl2 (Montrer BCL2 Anticorps) proteins.

  4. Chronically activated, monomeric PDGFRA (Montrer PDGFRA Anticorps) induced prolonged activation of Akt (Montrer AKT1 Anticorps) and suppressed the level of p53.

  5. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of TP53 transcripts and protein depending on luteal stage.

Xenopus laevis Tumor Protein P53 (TP53) interaction partners

  1. The stabilities of the full-length p53 orthologs were marginal and correlated with the temperature of their organism, paralleling the stability of the isolated DNA-binding domains.

  2. PP2A:B56{epsilon}, a substrate of caspase-3 (Montrer CASP3 Anticorps), regulates p53-dependent and p53-independent apoptosis during development.

  3. Furthermore, while activities to process procaspase-8 and procaspase-9 appeared in SAMDC-overexpressed apoptotic embryos, the activity to process procaspase-8 did not appear in p53-overexpressed apoptotic embryos. [SAMDC]

  4. XFDL156 actively restricts mesodermal differentiation in the presumptive ectoderm by controlling the spatiotemporal responsiveness to p53.

Cow (Bovine) Tumor Protein P53 (TP53) interaction partners

  1. The effect of p53 expression on the development of cloned embryos, and its interaction with HDAC1 (Montrer HDAC1 Anticorps) and DNMT3A (Montrer DNMT3A Anticorps) are reported.

  2. Bov-A2 insertion into the TP53 promoter in Antilopinae and Tragelaphini may not only provide a genetic network that regulates mammary involution, but can also answer the need for rapid mammary involution in Savanna antelopes

  3. PI3K/Akt (Montrer AKT1 Anticorps) and p53 are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  4. Results demonstrate that embryonic developmental potential is related to the time of first cleavage and that p66(shc), but not p53, is up-regulated in early arrested in vitro-produced bovine embryos.

Guinea Pig Tumor Protein P53 (TP53) interaction partners

  1. P53 may play an important role in impulse noise induced-hair cell apoptosis.

Horse (Equine) Tumor Protein P53 (TP53) interaction partners

  1. Expression of p53 and Ki67 (Montrer MKI67 Anticorps) and presence or expression of EcPV2 and EcPV3 do not appear to be important prognosticators.

  2. The allele frequency in Thoroughbred horse mares at codon 72 in exon 4 was 73.3% Arg/Pro, 17.1% Arg/Arg, 9.6% Pro/Pro. Presence of Arg/Pro was significantly associated with abortion, while Pro/Pro mares had a lower probability of abortion.

Zebrafish Tumor Protein P53 (TP53) interaction partners

  1. C/ebpalpha (Montrer CEBPA Anticorps) plays a role in liver growth regulation via the p53 pathway.

  2. Results demonstrate a novel role of Klf8 (Montrer KLF8 Anticorps), achieved via modulation of p53 and met expression, in the maintenance neuronal progenitors and development of Purkinje cells and the proliferation of granule cells in the cerebella of zebrafish embryos

  3. p53 has a limited role in eliciting the anemia phenotype of zebrafish models of Diamond-Blackfan anemia.

  4. p53 protein accumulates during tumor formation as a result of tumor-specific inactivation of the Mdm2 (Montrer MDM2 Anticorps) pathway.

  5. Apoptosis was also observed with myca expression; introduction of homozygous tp53(-/-) mutation into the myca transgenic fish reduced apoptosis and accelerated tumor progression.

  6. The crystal structure of the zebrafish p53 tetramerization domain.

  7. The identification of novel p53 isoforms with anti-apoptosis function generated due to alternative splicing of intron 8 of p53.

  8. L-Leucine thus alleviates anaemia in RP-deficient cells in a TP53-independent manner.

  9. By the loss-of-function of p53.

  10. Data suggest that the co-inhibition of Tp53 activity rescued the morphological deformities but did not alleviate the erythroid aplasia indicating that ribosomal protein deficiency causes erythroid failure in a Tp53-independent manner.

Rainbow Trout (Oncorhynchus mykiss) Tumor Protein P53 (TP53) interaction partners

  1. levels of p53 in rainbow trout tissues and cell lines reported; detection of high p53 levels in gills may reflect need for elevated checkpoint readiness in a tissue that would be expected to be accessible to genotoxic compounds in the aquatic environment

p53 (TP53) profil antigène

Antigen Summary

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).

Alternative names and synonyms associated with p53 (TP53)

  • cellular tumor antigen p53 (CpipJ_CPIJ002758) anticorps
  • tumor protein p53 (TP53) anticorps
  • tumor supressor p53 (tp53) anticorps
  • p53 tumor suppressor (P53) anticorps
  • transformation related protein 53 (Trp53) anticorps
  • transformation related protein 53, pseudogene (Trp53-ps) anticorps
  • trichoplein, keratin filament binding (TCHP) anticorps
  • tumor protein p53 (Tp53) anticorps
  • tumor protein p53 (tp53) anticorps
  • Wistar clone pR53P1 p53 pseudogene (p53-ps) anticorps
  • bbl anticorps
  • BCC7 anticorps
  • bfy anticorps
  • bhy anticorps
  • brp53 anticorps
  • drp53 anticorps
  • etID22686.5 anticorps
  • fb40d06 anticorps
  • LFS1 anticorps
  • p44 anticorps
  • P53 anticorps
  • Tp53 anticorps
  • TpMs anticorps
  • Trp53 anticorps
  • wu:fb40d06 anticorps
  • Xp53 anticorps
  • zgc:111919 anticorps

Protein level used designations for anti-Tumor Protein P53 (TP53) Anticorps

cellular tumor antigen p53 , tumor protein p53 (Li-Fraumeni syndrome) , tumor supressor p53 , Tumor suppressor p53 , Cellular tumor antigen p53 , p53 cellular tumor antigen , tumor suppressor p53 , mitochondrial protein with oncostatic activity , mitostatin , trichoplein keratin filament-binding protein , tumor suppressor protein , antigen NY-CO-13 , p53 tumor suppressor , phosphoprotein p53 , transformation-related protein 53 , transformation related protein 53 , Li-Fraumeni syndrome , tumor suppressor protein p53 , p53 tumor suppressor phosphoprotein , tumor protein 53 , P53 , tumor suppressing protein

GENE ID SPECIES
6033952 Culex quinquefasciatus
455214 Pan troglodytes
100304476 Ictalurus punctatus
100682525 Cricetulus griseus
22059 Mus musculus
22060 Mus musculus
84260 Homo sapiens
7157 Homo sapiens
24842 Rattus norvegicus
443421 Ovis aries
403869 Canis lupus familiaris
397276 Sus scrofa
100009292 Oryctolagus cuniculus
397926 Xenopus laevis
281542 Bos taurus
100379269 Cavia porcellus
493847 Felis catus
396200 Gallus gallus
100062044 Equus caballus
716170 Macaca mulatta
30590 Danio rerio
100136737 Oncorhynchus mykiss
301300 Rattus norvegicus
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