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Aperçu des produits pour anti-p53 (TP53) Anticorps

Full name:
anti-Tumor Protein P53 Anticorps (TP53)
Chez www.anticorps-enligne.fr sont 2261 Tumor Protein P53 (TP53) Anticorps de 50 de différents fournisseurs disponibles. De plus, nous expédions p53 Kits (118) et p53 Protéines (78) et beaucoup plus de produits pour cette protéine. Un total de 2620 p53 produits sont actuellement listés.
Synonymes:
bbl, BCC7, bfy, bhy, brp53, drp53, etID22686.5, fb40d06, LFS1, p44, P53, Tp53, TpMs, Trp53, wu:fb40d06, Xp53, zgc:111919

Tous anti-p53 Anticorps disponible

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anti-p53 Anticorps mieux référencés

  1. Human Monoclonal p53 Primary Antibody pour IHC (f), IHC (fro) - ABIN967416 : Cheng, Yee, Yeargin, Friedmann, Haas: Suppression of acute lymphoblastic leukemia by the human wild-type p53 gene. dans Cancer research 1992 (PubMed)
    Show all 11 references for ABIN967416

  2. Human Polyclonal p53 Primary Antibody pour IF, IHC (p) - ABIN390204 : Blanchette, Cheng, Yan, Ketner, Ornelles, Dobner, Conaway, Conaway, Branton: Both BC-box motifs of adenovirus protein E4orf6 are required to efficiently assemble an E3 ligase complex that degrades p53. dans Molecular and cellular biology 2004 (PubMed)
    Show all 4 references for ABIN390204

  3. Human Monoclonal p53 Primary Antibody pour IHC (fro), IF - ABIN1108553 : Isobe, Emanuel, Givol, Oren, Croce: Localization of gene for human p53 tumour antigen to band 17p13. dans Nature 1986 (PubMed)
    Show all 2 references for ABIN1108553

  4. Human Polyclonal p53 Primary Antibody pour IHC, ELISA - ABIN1531939 : Lohrum, Scheidtmann: Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes. dans Oncogene 1997 (PubMed)

  5. Human Polyclonal p53 Primary Antibody pour ELISA, WB - ABIN1531937 : Kyriakis, Banerjee, Nikolakaki, Dai, Rubie, Ahmad, Avruch, Woodgett: The stress-activated protein kinase subfamily of c-Jun kinases. dans Nature 1994 (PubMed)

  6. Cow (Bovine) Polyclonal p53 Primary Antibody pour WB - ABIN2779979 : Rotter, Wolf, Pravtcheva, Ruddle: Chromosomal assignment of the murine gene encoding the transformation-related protein p53. dans Molecular and cellular biology 1984 (PubMed)

  7. Human Polyclonal p53 Primary Antibody pour ChIP, ELISA - ABIN2779319 : Boehme, Kulikov, Blattner: p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK. dans Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

Plus d’anticorps contre p53 partenaires d’interaction

Mouse (Murine) Tumor Protein P53 (TP53) interaction partners

  1. present the first mouse model of mucinous tumor formation from ovarian cells and supporting evidence that mutant TP53 is a key regulator of EOC progression, differentiation, and responsiveness to steroid hormones

  2. Inhibition of MDM2 (Montrer MDM2 Anticorps) re-sensitizes rapamycin resistant renal cancer cells via the activation of p53.

  3. Apple pectin could inhibit the progression of breast tumors by up-regulating the expression of TP53 and increasing the number of apoptotic cells.

  4. Study suggests that p53 is transcriptionally active in the brains of Down syndrome individuals and is associated with an increase in apoptotic markers in the presence of Alzheimer's disease pathology

  5. MYSM1 (Montrer MYSM1 Anticorps) is a critical negative regulator of p53 transcriptional programs in hematopoiesis, and its repression of Bbc3/PUMA (Montrer BBC3 Anticorps) expression is essential for multipotent progenitor survival, and partly contributes to maintaining hematopoietic stem cell function

  6. Therapeutic response to non-genotoxic activation of p53 by Nutlin3a is driven by PUMA (Montrer BBC3 Anticorps)-mediated apoptosis in lymphoma cells.

  7. Jmjd5 (Montrer JMJD5 Anticorps) is involved in the transcriptional regulation of a subset of p53-regulated genes, possibly through the control of p53 recruitment at the gene loci.

  8. results suggest that by inducing an atypical ISR and p53-independent apoptosis, ONC201 has clinical potential in hematological malignancies.

  9. alpha-synuclein (Montrer SNCA Anticorps) as a new transcriptional target of p53 and delineated a cellular mechanism feeding the accumulation of toxic aggregated alpha-synuclein (Montrer SNCA Anticorps) in Parkinson's disease

  10. The novel mechanism of IL-15 (Montrer IL15 Anticorps) transfer to the surface of antigen-processing DCs may explain the enhanced potency of IL-15 (Montrer IL15 Anticorps):IL-15Ralpha-coated nanoparticles for antigen delivery.

Human Tumor Protein P53 (TP53) interaction partners

  1. that p53 immunoexpression in more than 1% of the cells in a cutaneous smooth muscle tumor is indicative of malignancy

  2. identification of the oncoprotein SET as a major cellular factor whose binding with p53 is dependent on C-terminal domain acetylation status

  3. Long term expression of p53 responsive miRNAs leads to an excess of miRNAs during the second response and this likely prevents the induction of MDM2 (Montrer MDM2 Anticorps), BTG2 (Montrer BTG2 Anticorps) and CDKN1A mRNA and/or protein.

  4. By upregulating p53 and p21 (Montrer CDKN1A Anticorps) expression and inhibiting Akt (Montrer AKT1 Anticorps) (Ser473) phosphorylation, SEMA3B (Montrer SEMA3B Anticorps) could induce cell cycle arrest at G1/S phase.

  5. Increased expression of p53 and ASPP1 (Montrer PPP1R13B Anticorps) and downregulation of iASPP (Montrer PPP1R13L Anticorps).

  6. the TP53 codon 72 polymorphism is not associated with RIF risk in the overall population; however, associations were found in the Latin American population (Meta-Analysis)

  7. EZH2 (Montrer EZH2 Anticorps) and p53, which affect lymph node metastasis and prognosis of SCC (Montrer CYP11A1 Anticorps), may play a key role in the occurrence and development of SCC (Montrer CYP11A1 Anticorps).

  8. miR (Montrer MLXIP Anticorps)-34a has a crucial role in the pathogenesis of osteoarthritis through direct regulation of the SIRT1 (Montrer SIRT1 Anticorps)/p53 signaling pathway.

  9. We also uncovered the suppression of the p53 signaling pathway that mediated the activity of USP7 (Montrer USP7 Anticorps) and LSD1 (Montrer KDM1A Anticorps). Furthermore, USP7 (Montrer USP7 Anticorps) and LSD1 (Montrer KDM1A Anticorps) expression levels were higher in the 150 glioma patients than these levels in normal brain tissues and were correlated with glioma progression.

  10. Our results suggest that PIN1 (Montrer PIN1 Anticorps) plays a role in cancer cell proliferation, migration and invasion in a different manner according to the TP53 gene mutation status in hepatocellular carcinoma

Pig (Porcine) Tumor Protein P53 (TP53) interaction partners

  1. This study demonstrated that various expression levels of p53 in porcine fibroblasts could be achieved by gene targeting and RNA interference.

  2. SIRT1 (Montrer SIRT1 Anticorps), p53 and NF-kappaB (Montrer NFKB1 Anticorps) are involved in the control of both the proliferation and the apoptosis of ovarian cells.

  3. Taken together,these results demonstrated that Porcine parvovirus infection induced apoptosis in PK-15 cells through activation of p53 and mitochondria-mediated apoptosis pathway.

  4. Data indicate that higher hepatic glucocorticoid receptor (GR (Montrer NR3C1 Anticorps)) expression in EHL piglets attributes mainly to the enhanced transcription of GR promoter 1-9/10 from breed-specific interaction of p53 and specificity protein 1 (Sp1 (Montrer SP1 Anticorps)).

  5. Taken together, these results demonstrated that transmissible gastroenteritis virus infection promoted the activation of p38 MAPK (Montrer MAPK14 Anticorps) and p53 signalling, and p53 signalling might play a dominant role in the regulation of cell apoptosis.

  6. role of transcription factor p53 and the metabolic hormone leptin (Montrer LEP Anticorps), in controlling basic functions (proliferation, apoptosis and secretory activity) of ovarian cells

  7. differential expression of p53 pathway-related genes accounts for breed-specific skeletal muscle and meat characteristics

  8. CONCLUSION(S): (1) Apoptosis is involved in follicular atresia; (2) Bcl-2 (Montrer BCL2 Anticorps) is induced by warm ischemia; and (3) cryopreservation insult does not alter the apoptotic signals with short tissue preparation time.

  9. Suppressive effect of FSH (Montrer BRD2 Anticorps) and LH on p53 expression and caspase-3 (Montrer CASP3 Anticorps) activity with parallel increase in bcl-2 (Montrer BCL2 Anticorps) expression and increased P production was observed.

  10. p53 signaling might be a major determinant for the replicative senescence in the miniature pig fibroblast cells that have the shorter lifespan and slower growth rate compared to primary domestic pig fibroblast cells in vitro.

Rabbit Tumor Protein P53 (TP53) interaction partners

  1. Suppressing expression of p53 was a required event in two assays of proliferative vitreoretinopathy.

  2. These results suggest that p38 MAPK (Montrer MAPK14 Anticorps) signal transduction pathway is critical to NO-induced chondrocyte apoptosis, and p38 (Montrer MAPK14 Anticorps) plays a role by way of stimulating NF-kappaB (Montrer NFKB1 Anticorps), p53 and caspase-3 (Montrer CASP3 Anticorps) activation.

  3. Our data indicate that exposure to rabbits to Pb(Ac)(2) caused a significant increase of apoptosis protein p53 and decrease in the antiapoptotic BCl2 (Montrer BCL2 Anticorps) proteins.

  4. Chronically activated, monomeric PDGFRA (Montrer PDGFRA Anticorps) induced prolonged activation of Akt (Montrer AKT1 Anticorps) and suppressed the level of p53.

  5. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of TP53 transcripts and protein depending on luteal stage.

Xenopus laevis Tumor Protein P53 (TP53) interaction partners

  1. The stabilities of the full-length p53 orthologs were marginal and correlated with the temperature of their organism, paralleling the stability of the isolated DNA-binding domains.

  2. PP2A:B56{epsilon}, a substrate of caspase-3 (Montrer CASP3 Anticorps), regulates p53-dependent and p53-independent apoptosis during development.

  3. Furthermore, while activities to process procaspase-8 and procaspase-9 appeared in SAMDC-overexpressed apoptotic embryos, the activity to process procaspase-8 did not appear in p53-overexpressed apoptotic embryos. [SAMDC]

  4. XFDL156 actively restricts mesodermal differentiation in the presumptive ectoderm by controlling the spatiotemporal responsiveness to p53.

Cow (Bovine) Tumor Protein P53 (TP53) interaction partners

  1. The effect of p53 expression on the development of cloned embryos, and its interaction with HDAC1 (Montrer HDAC1 Anticorps) and DNMT3A (Montrer DNMT3A Anticorps) are reported.

  2. Bov-A2 insertion into the TP53 promoter in Antilopinae and Tragelaphini may not only provide a genetic network that regulates mammary involution, but can also answer the need for rapid mammary involution in Savanna antelopes

  3. PI3K/Akt (Montrer AKT1 Anticorps) and p53 are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  4. Results demonstrate that embryonic developmental potential is related to the time of first cleavage and that p66(shc), but not p53, is up-regulated in early arrested in vitro-produced bovine embryos.

Guinea Pig Tumor Protein P53 (TP53) interaction partners

  1. P53 may play an important role in impulse noise induced-hair cell apoptosis.

Horse (Equine) Tumor Protein P53 (TP53) interaction partners

  1. Expression of p53 and Ki67 (Montrer MKI67 Anticorps) and presence or expression of EcPV2 and EcPV3 do not appear to be important prognosticators.

  2. The allele frequency in Thoroughbred horse mares at codon 72 in exon 4 was 73.3% Arg/Pro, 17.1% Arg/Arg, 9.6% Pro/Pro. Presence of Arg/Pro was significantly associated with abortion, while Pro/Pro mares had a lower probability of abortion.

Zebrafish Tumor Protein P53 (TP53) interaction partners

  1. C/ebpalpha (Montrer CEBPA Anticorps) plays a role in liver growth regulation via the p53 pathway.

  2. Results demonstrate a novel role of Klf8 (Montrer KLF8 Anticorps), achieved via modulation of p53 and met expression, in the maintenance neuronal progenitors and development of Purkinje cells and the proliferation of granule cells in the cerebella of zebrafish embryos

  3. p53 has a limited role in eliciting the anemia phenotype of zebrafish models of Diamond-Blackfan anemia.

  4. p53 protein accumulates during tumor formation as a result of tumor-specific inactivation of the Mdm2 (Montrer MDM2 Anticorps) pathway.

  5. Apoptosis was also observed with myca expression; introduction of homozygous tp53(-/-) mutation into the myca transgenic fish reduced apoptosis and accelerated tumor progression.

  6. The crystal structure of the zebrafish p53 tetramerization domain.

  7. The identification of novel p53 isoforms with anti-apoptosis function generated due to alternative splicing of intron 8 of p53.

  8. L-Leucine thus alleviates anaemia in RP-deficient cells in a TP53-independent manner.

  9. By the loss-of-function of p53.

  10. Data suggest that the co-inhibition of Tp53 activity rescued the morphological deformities but did not alleviate the erythroid aplasia indicating that ribosomal protein deficiency causes erythroid failure in a Tp53-independent manner.

Rainbow Trout (Oncorhynchus mykiss) Tumor Protein P53 (TP53) interaction partners

  1. levels of p53 in rainbow trout tissues and cell lines reported; detection of high p53 levels in gills may reflect need for elevated checkpoint readiness in a tissue that would be expected to be accessible to genotoxic compounds in the aquatic environment

p53 (TP53) profil antigène

Antigen Summary

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).

Alternative names and synonyms associated with p53 (TP53)

  • cellular tumor antigen p53 (CpipJ_CPIJ002758) anticorps
  • tumor protein p53 (TP53) anticorps
  • tumor supressor p53 (tp53) anticorps
  • p53 tumor suppressor (P53) anticorps
  • transformation related protein 53 (Trp53) anticorps
  • transformation related protein 53, pseudogene (Trp53-ps) anticorps
  • trichoplein, keratin filament binding (TCHP) anticorps
  • tumor protein p53 (Tp53) anticorps
  • tumor protein p53 (tp53) anticorps
  • Wistar clone pR53P1 p53 pseudogene (p53-ps) anticorps
  • bbl anticorps
  • BCC7 anticorps
  • bfy anticorps
  • bhy anticorps
  • brp53 anticorps
  • drp53 anticorps
  • etID22686.5 anticorps
  • fb40d06 anticorps
  • LFS1 anticorps
  • p44 anticorps
  • P53 anticorps
  • Tp53 anticorps
  • TpMs anticorps
  • Trp53 anticorps
  • wu:fb40d06 anticorps
  • Xp53 anticorps
  • zgc:111919 anticorps

Protein level used designations for anti-Tumor Protein P53 (TP53) Anticorps

cellular tumor antigen p53 , tumor protein p53 (Li-Fraumeni syndrome) , tumor supressor p53 , Tumor suppressor p53 , Cellular tumor antigen p53 , p53 cellular tumor antigen , tumor suppressor p53 , mitochondrial protein with oncostatic activity , mitostatin , trichoplein keratin filament-binding protein , tumor suppressor protein , antigen NY-CO-13 , p53 tumor suppressor , phosphoprotein p53 , transformation-related protein 53 , transformation related protein 53 , Li-Fraumeni syndrome , tumor suppressor protein p53 , p53 tumor suppressor phosphoprotein , tumor protein 53 , P53 , tumor suppressing protein

GENE ID SPECIES
6033952 Culex quinquefasciatus
455214 Pan troglodytes
100304476 Ictalurus punctatus
100682525 Cricetulus griseus
22059 Mus musculus
22060 Mus musculus
84260 Homo sapiens
7157 Homo sapiens
24842 Rattus norvegicus
443421 Ovis aries
403869 Canis lupus familiaris
397276 Sus scrofa
100009292 Oryctolagus cuniculus
397926 Xenopus laevis
281542 Bos taurus
100379269 Cavia porcellus
493847 Felis catus
396200 Gallus gallus
100062044 Equus caballus
716170 Macaca mulatta
30590 Danio rerio
100136737 Oncorhynchus mykiss
301300 Rattus norvegicus
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