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Up-regulated expression of CBP (Montrer CREBBP Kits ELISA) in Jurkat cells could reduce cell homogeneity and promote cell apoptosis
No association Pag1 mutation with patient with Schizophrenia.
The risk-associated allele of rs2370615 predisposes to allergic disease by increasing PAG1 expression, which might promote B cell activation (Montrer BLNK Kits ELISA) and have a pro-inflammatory effect.
CBP (Montrer CREBBP Kits ELISA) may decrease the metastasis of esophageal carcinoma by inhibiting the activation of Src (Montrer SRC Kits ELISA).
The inhibitory function of novobiocin in disrupting the HIF1alpha (Montrer HIF1A Kits ELISA)/p300 (Montrer EP300 Kits ELISA) complex might be important in tumor cell growth.
siRNA directed against PAG1 in a radioresistant (Hep-2max) cell line dramatically enhanced the radiosensitivity and IR-induced cell death.
expression of CBP (Montrer CREBBP Kits ELISA) gene is decreased in esophageal carcinoma, which might contribute to the tumorigenesis and progression.
An over-expression of PAG1 in PC-3M-1E8 cells effectively suppresses the activation of Ras and ERK (Montrer EPHB2 Kits ELISA), as well as the cyclin D1 (Montrer CCND1 Kits ELISA) expression, leading to an inhibition of the proliferation ability of tumor cells.
Cbp (Montrer CREBBP Kits ELISA) down-regulation is primarily mediated by epigenetic histone modifications via oncogenic MAPK (Montrer MAPK1 Kits ELISA)/PI3K (Montrer PIK3CA Kits ELISA) pathways in a subset of cancer cells.
Results indicate that Cbp is required for the Csk-mediated inactivation of c-Src and may control the promotion of malignancy in NSCLC tumors that are characterized by c-Src upregulation.
Intrinsic mitochondrial oxidative capacity was significantly increased in skeletal muscle of aged PAPP-A (Montrer PAPPA Kits ELISA) KO compared to WT mice. Moreover, 18-month-old PAPP-A (Montrer PAPPA Kits ELISA) KO mice exhibited significantly enhanced endurance running on a treadmill. Thus, PAPP-A (Montrer PAPPA Kits ELISA) deficiency in mice is associated with indices of healthy skeletal muscle function with age.
our findings illustrate that Cbp (Montrer CREBBP Kits ELISA) is an important regulator of Csk (Montrer CSK Kits ELISA) recruitment to the SFK Lyn (Montrer LYN Kits ELISA) in Eporesponsive erythroid cells.
Snell, GHKRO, and PAPPA (Montrer PAPPA Kits ELISA)-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT (Montrer MGMT Kits ELISA)) and N-myc downstream-regulated gene 1 (NDRG1 (Montrer NDRG1 Kits ELISA)).
STC2 (Montrer STC2 Kits ELISA) is involved in regulating PAPP-A (Montrer PAPPA Kits ELISA) activity during the development of atherosclerosis
Study demonstrates proof-of-principle and provides feasibility for a novel therapeutic strategy to inhibit atherosclerotic plaque burden by selective targeting of PAPP-A (Montrer PAPPA Kits ELISA).
stimulation of PAPP-A (Montrer PAPPA Kits ELISA) expression by intermittent PTH (Montrer PTH Kits ELISA) treatment contributes to PTH (Montrer PTH Kits ELISA) bone anabolism in mice
PAPP-A (Montrer PAPPA Kits ELISA) affects fascicle structure, thereby affecting tendon phenotype.
This study demonstrated that cbp (Montrer CREBBP Kits ELISA) increase in skeletal muscle in muscle atrophy.
PAG is constitutively phosphorylated in resting T cells and rapidly dephosphorylated once the TCR is engaged.
If Cbp enhances the interaction between c-Src and FAK, Cbp could promote c-Src function when lipid rafts are disrupted.
The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell activation.
phosphoprotein associated with glycosphingolipid microdomains 1
, phosphoprotein associated with glycosphingolipid-enriched microdomains 1-like
, Csk-binding protein
, phosphoprotein associated with glycosphingolipid-enriched microdomains 1
, transmembrane adapter protein PAG
, transmembrane adaptor protein PAG
, transmembrane phosphoprotein Cbp
, Csk binding protein
, csk-binding protein
, phosphoprotein transmembrane adaptor 1
, phosphoprotein-associated with GEMs
, IGF-dependent IGFBP-4 protease
, insulin-like growth factor-dependent IGF-binding protein 4 protease