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Aperçu des produits pour anti-AKT (AKT1) Anticorps

Full name:
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 Anticorps (AKT1)
Chez www.anticorps-enligne.fr sont 1159 V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Anticorps de 44 de différents fournisseurs disponibles. De plus, nous expédions AKT Kits (56) et AKT Protéines (46) et beaucoup plus de produits pour cette protéine. Un total de 1360 AKT produits sont actuellement listés.
Synonymes:
akt, akt-1, Akt/PKB, akt1, ATAKT1, CG4006, CWS6, D-Akt, dakt, dAKT/dPKB, dAkt/PKB, dakt1, DAKT1/PKB, Dmel\\CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, F18A8.2, F18A8_2, K+ transporter 1, l(3)04226, l(3)89Bq, p-Akt, pAkt, PKB, PKB-ALPHA, PKB/Akt, PKB/dAKT, PKBalpha, POTASSIUM TRANSPORTER, PRKBA, Rac, RAC-ALPHA, RacPK, v-akt, v-akt1, xAct

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anti-AKT Anticorps mieux référencés

  1. Human Polyclonal AKT Primary Antibody pour FACS, WB - ABIN652283 : Liao, Grobholz, Abel, Trojan, Michel, Angel, Mayer: Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer. dans International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 4 references for ABIN652283

  2. Human Monoclonal AKT Primary Antibody pour EIA, IF - ABIN400786 : Jones, Jakubowicz, Pitossi, Maurer, Hemmings: Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. dans Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 4 references for ABIN400786

  3. Chimpanzee Monoclonal AKT Primary Antibody pour EIA, IF - ABIN400784 : Staal: Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. dans Proceedings of the National Academy of Sciences of the United States of America 1987 (PubMed)
    Show all 4 references for ABIN400784

  4. Human Polyclonal AKT Primary Antibody pour IF (p), IHC (p) - ABIN725195 : Xu, Huang, Xie, Lin, Guo, Zhuang, Lin, Zhou, Li, Huang, Wei, Man, Zhang: The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients. dans BMC cancer 2013 (PubMed)
    Show all 3 references for ABIN725195

  5. Chicken Polyclonal AKT Primary Antibody pour EIA, IHC (fro) - ABIN117897 : Lawlor, Alessi: PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? dans Journal of cell science 2001 (PubMed)
    Show all 2 references for ABIN117897

  6. Human Polyclonal AKT Primary Antibody pour DB, IF - ABIN650880 : Chen, Gomes, Monteiro, Wong, Wu, Ng, Karadedou, Millour, Ip, Cheung, Sunters, Chan, Lam, Khoo: Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer. dans PLoS ONE 2010 (PubMed)

Plus d’anticorps contre AKT partenaires d’interaction

Fruit Fly (Drosophila melanogaster) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. subtle manipulation of foxo (Montrer FOXO Anticorps) through Akt1 can enhance survival during adverse nutrient conditions in Drosophila.

  2. The developmental delay of these novel Akt1 hypomorphs results in a latent phenotype uncovered by generation of somatic clones

  3. these data show that Drosophila Trbl has a conserved role to bind Akt and block Akt-mediated insulin signaling, and implicate Trib proteins as novel sites of signaling pathway integration that link nutrient availability with cell growth and proliferation

  4. AKT1 and caspase-dependent regulation of Acn stability adjusts basal autophagy levels.

  5. Akt1 governs two critical elements of synapse development, neurotransmitter receptor (Montrer GRIN1 Anticorps) localization, and postsynaptic membrane elaboration

  6. Tsc2 (Montrer TSC2 Anticorps) mutants showed a dramatic decrease in the levels of phosphorylated Akt, and interestingly, Akt mutants phenocopied Tsc2 (Montrer TSC2 Anticorps) mutants, leading to the hypothesis that Tsc2 (Montrer TSC2 Anticorps) and Akt might work via the same genetic pathway to regulate synapse growth.

  7. Hippo signaling not only blocks cell division and promotes apoptosis, but also regulates cellular growth by inhibiting the Akt pathway activity.

  8. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten (Montrer PTEN Anticorps) and microRNA bantam.

  9. Overexpression of Akt enhanced Sindbis virus replication.

  10. Perturbation of the Akt/Gsk3-beta (Montrer GSK3b Anticorps) signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.

Arabidopsis thaliana V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. CIPK23 and AtKC1 exhibit distinct effects; however, they act synergistically and balance K(+) uptake/leakage to modulate AKT1-mediated low potassium responses in Arabidopsis.

  2. results suggest that NO decreases K(+) absorption by promoting the synthesis of vitamin B6 PLP (Montrer FNTA Anticorps), which further represses the activity of K(+) channel (Montrer KCNC4 Anticorps) AKT1 in Arabidopsis.

  3. Examination of the athak5 atakt1 double mutant, revealing novel aspects of an uptake system as yet unidentified by genetic means.

  4. AKT1 is regulated by CIPK23 in guard cells and is involved in water stress responses.

  5. These findings provide further insights into the signaling network consisting of CBL (Montrer CBL Anticorps)-CIPK-PP2C interactions in the activation of the AKT1 channel.

  6. Electrophysiological results showed that AtKC1 inhibited the AKT1-mediated inward K(+) currents and negatively shifted the voltage dependence of AKT1 channels.

  7. AtHAK5 and AKT1 are vital for plant growth and development at low K+ concentrations.

  8. In the range between 0.01 and 0.05 mM K+ AtHAK5 and AtAKT1 are the only contributors to K+ acquisition. At higher K+ concentrations, unknown systems come into operation and participate together with AtAKT1 in low-affinity K+ uptake.

  9. CIPK23 directly phosphorylates the K+ transporter AKT1

  10. Data show that interacting calcium sensors (CBL1 and CBL9) together with CIPK23, but not either alone, activated the AKT1 channel in a Ca(2 (Montrer CA2 Anticorps)+)-dependent manner, connecting the Ca(2 (Montrer CA2 Anticorps)+) signal to K(+) uptake through activation of a K(+) channel (Montrer KCNC4 Anticorps).

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. A cell-culture study using an inhibitor of estrogen receptors and an in vivo experiment with ovariectomized mice suggested that the estrogenic activity of 8-PN contributed to recovery from disuse muscle atrophy through activation of an Akt phosphorylation pathway. These data strongly suggest that 8-PN is a naturally occurring compound that could be used as a nutritional supplement to aid recovery from disuse muscle atroph

  2. Analysis of the successful model also elucidates two dynamical motifs: neutralization of a negative regulator, which characterizes how Akt indirectly activates mTORC1, and seesaw enzyme regulation, which describes how activated and inhibited states of mTORC1 are controlled in concert to produce a nonlinear, ultrasensitive response

  3. Data show that Akt/mTOR (Montrer FRAP1 Anticorps) and MAPK (Montrer MAPK1 Anticorps) pathways were activated in ovine pulmonary adenocarcinoma (OPA) lung and envelope (Env (Montrer ERVW-1 Anticorps)) of Jaagsiekte sheep retrovirus (JSRV) transfected NIH 3T3 cells.

  4. Results suggest that SC79 compound activates Akt-Nrf2 (Montrer NFE2L2 Anticorps) signaling to protect osteoblasts from dexamethasone (Dex).

  5. In conclusion, we have identified that ARL15 acts as an insulin (Montrer INS Anticorps)-sensitizing effector molecule to upregulate the phosphorylation of members of the canonical IR/IRS1 (Montrer IRS1 Anticorps)/PDPK1 (Montrer PDPK1 Anticorps)/AKT insulin (Montrer INS Anticorps) pathway by interacting with its GAP ASAP2 (Montrer ASAP2 Anticorps) and activating PDPK1 (Montrer PDPK1 Anticorps). This research may provide new insights into GTPase (Montrer RACGAP1 Anticorps)-mediated insulin (Montrer INS Anticorps) signalling regulation and facilitate the development of new pharmacotherapeutic targets for insulin (Montrer INS Anticorps) sensitizati

  6. Taken together, our findings imply that KLF15 possesses potential anti-hypertrophic and anti-fibrotic functions, possibly via regulation of cell death pathways and the inhibition of Akt/mTOR axis. KLF15 may constitute an efficient candidate drug for the treatment of heart failure and other cardiovascular diseases.

  7. Menin (Montrer MEN1 Anticorps) binds on the promoter of Inhbb (Montrer INHBB Anticorps) gene where it favours the recruitment of Ezh2 (Montrer EZH2 Anticorps) via an indirect mechanism involving Akt-phosphorylation.

  8. A role of AKT in the regulatory T cell differentiation process. TGF-beta (Montrer TGFB1 Anticorps) induces the phosphorylation of Akt in CD4 (Montrer CD4 Anticorps)+ T cells.

  9. 4-PBA reverses autophagic dysfunction and improves insulin (Montrer INS Anticorps) sensitivity in adipose tissue of obese mice via Akt/mTOR (Montrer FRAP1 Anticorps) signaling partly, which could be regarded as novel opportunities for treatment of insulin (Montrer INS Anticorps) resistance.

  10. These studies reveal a novel mechanism in which CYP2J2 (Montrer CYP2J2 Anticorps) and epoxyeicosatrienoic acids enhanced Akt1 nuclear translocation through interaction with AMPKalpha2beta2gamma1 and protect against cardiac hypertrophy.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin, a process in part mediated through the PI3-kinase (Montrer PIK3CA Anticorps)-Akt/PKB cell survival pathway. These results provide further rationale for clinical investigation of relaxin as a potential therapeutic in preeclampsia.

  2. Binding of PP2A (Montrer PPP2R4 Anticorps) and Akt increased in response to cAMP or phosphatidic acid (PA), suggesting that their binding is directly responsible for the inactivation of Akt during decidualization.

  3. Results suggest that polymorphism of AKT1 locus is associated with risk of Parkinson's disease and that the G allele at rs2498799 may decrease the risk of Parkinson's disease in the North-eastern part of Han Chinese female population.

  4. Akt phosphorylates inversin (Montrer INVS Anticorps) at amino acids 864-866 that are required not only for Akt interaction, but also for inversin (Montrer INVS Anticorps) dimerization.

  5. In vitro study using human endothelial cells showed that prostaglandin E2 (PGE2) significantly increased MMP-2 (Montrer MMP2 Anticorps) activity as well as tube formation. Inhibition of COX-2 (Montrer COX2 Anticorps) and/or phosphorylated AKT suppressed MMP-2 (Montrer MMP2 Anticorps) activity and endothelial tube formation suggesting involvement of PGE2 in regulation of MMP-2 (Montrer MMP2 Anticorps) activity during angiogenesis.

  6. p-PTEN (Montrer PTEN Anticorps), Akt, p-PDK1 (Montrer PDK1 Anticorps), and p-GSK-3beta (Montrer GSK3b Anticorps) were significantly downregulated after the knockdown of CK2alpha expression.

  7. the results show that EphA2 (Montrer EPHA2 Anticorps) endows invasiveness of glioma stem cells in vivo in cooperation with Akt and regulates glioma stem cell properties

  8. We revealed that activation of the PI3K (Montrer PIK3CA Anticorps)/Akt pathway was the main cause of impaired autophagy in ELK3 (Montrer ELK3 Anticorps) KD. Our results suggest that targeting ELK3 (Montrer ELK3 Anticorps) may be a potential approach to overcome doxorubicin resistance in breast cancer therapeutics.

  9. Our results show a miRNA editing activity trend aligning with cellular pathways closely associated to hypoxia, such as the VEGF (Montrer VEGFA Anticorps) and PI3K (Montrer PIK3CA Anticorps)/Akt pathways, providing important novel insights on this poorly elucidated phenomenon.

  10. CYT (Montrer CYGB Anticorps)-Rx20 significantly reduced tumor growth of the implanted esophageal cancer cells accompanied by decreased Ki-67 (Montrer MKI67 Anticorps), phospho-AKT, and phospho-STAT3 (Montrer STAT3 Anticorps) expression.

Pig (Porcine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR (Montrer FRAP1 Anticorps)-FOXO1 (Montrer FOXO1 Anticorps) signaling and suppressing the activation of TLR4 (Montrer TLR4 Anticorps) and/or NOD2 (Montrer NOD2 Anticorps) signaling pathways.

  2. Data show that homocysteine (Hcy) can ameliorate the endothelium-independent hypoxic coronary vasoconstriction, in which the inhibition of PI3K/Akt signaling pathway may be involved.

  3. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 could positively regulate lactose synthesis.

  4. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  5. Host PI3K and Akt1 play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  6. Activity of AKT is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  7. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  8. findings show that megalin (Montrer LRP2 Anticorps) is the sensor that determines whether cells will be protected or injured by albumin (Montrer ALB Anticorps); it binds protein kinase B (PKB) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB in the luminal plasma membrane [

  9. protein kinase B (PKB/Akt)was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  10. Akt signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results demonstrate that activation of AKT is required for gonadotropin regulation of CTNNB1 (Montrer CTNNB1 Anticorps) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (Montrer CAV1 Anticorps) scaffolding domain residue phenylalanine 92 modulates Akt signaling

  3. TG2 (Montrer TGM2 Anticorps) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (Montrer GSK3b Anticorps), and NF-kappaB (Montrer NFKB1 Anticorps).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (Montrer NOX1 Anticorps), reactive oxygen species, and PI3-kinase (Montrer PIK3CA Anticorps) in stimulated NO release.

  6. PI3K/Akt and p53 (Montrer TP53 Anticorps) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR (Montrer FRAP1 Anticorps), p70S6K (Montrer RPS6KB1 Anticorps), and ERK1/2 (Montrer MAPK1/3 Anticorps).

  8. Gab1 (Montrer GAB1 Anticorps) tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B and endothelial nitric-oxide synthase (Montrer NOS3 Anticorps) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (Montrer NOS3 Anticorps) phosphorylation and suppresses tumor necrosis factor alpha (Montrer TNF Anticorps)-induced endothelial cell apoptosis by activating AKT1.

  10. prostaglandin F2alpha phosphorylates TSC2 (Montrer TSC2 Anticorps) and activates mTOR (Montrer FRAP1 Anticorps) and ribosomal protein S6 (Montrer RPS6 Anticorps) kinase (Montrer RPS6KB1 Anticorps) signaling in an AKT-independent manner

AKT (AKT1) profil antigène

Antigen Summary

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with AKT (AKT1)

  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) anticorps
  • v-akt murine thymoma viral oncogene homolog 1 (akt1) anticorps
  • CG4006 gene product from transcript CG4006-RA (Akt1) anticorps
  • potassium channel AKT1 (KT1) anticorps
  • thymoma viral proto-oncogene 1 (Akt1) anticorps
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) anticorps
  • akt anticorps
  • akt-1 anticorps
  • Akt/PKB anticorps
  • akt1 anticorps
  • ATAKT1 anticorps
  • CG4006 anticorps
  • CWS6 anticorps
  • D-Akt anticorps
  • dakt anticorps
  • dAKT/dPKB anticorps
  • dAkt/PKB anticorps
  • dakt1 anticorps
  • DAKT1/PKB anticorps
  • Dmel\\CG4006 anticorps
  • dPKB anticorps
  • DRAC-PK anticorps
  • DRAC-PK66 anticorps
  • DRAC-PK85 anticorps
  • F18A8.2 anticorps
  • F18A8_2 anticorps
  • K+ transporter 1 anticorps
  • l(3)04226 anticorps
  • l(3)89Bq anticorps
  • p-Akt anticorps
  • pAkt anticorps
  • PKB anticorps
  • PKB-ALPHA anticorps
  • PKB/Akt anticorps
  • PKB/dAKT anticorps
  • PKBalpha anticorps
  • POTASSIUM TRANSPORTER anticorps
  • PRKBA anticorps
  • Rac anticorps
  • RAC-ALPHA anticorps
  • RacPK anticorps
  • v-akt anticorps
  • v-akt1 anticorps
  • xAct anticorps

Protein level used designations for AKT1

RAC-alpha serine/threonine-protein kinase , protein kinase B , v-akt murine thymoma viral oncogene homolog 1 , Akt kinase , Akt1-PA , Akt1-PB , Akt1-PC , CG4006-PA , CG4006-PB , CG4006-PC , dAkt kinase , related to PKA to PKC protein kinases , related to the A and C kinases , AKT1 kinase , PKB alpha , RAC-PK-alpha , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , proto-oncogene c-Akt , rac protein kinase alpha , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , Akt , protein kinase Akt-1 , protein kinase B, alpha , xAkt , serine/threonine protein kinase , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1

GENE ID SPECIES
100294652 Ovis aries
697747 Macaca mulatta
740898 Pan troglodytes
100101714 Xenopus (Silurana) tropicalis
100490038 Xenopus (Silurana) tropicalis
41957 Drosophila melanogaster
100556289 Anolis carolinensis
100587109 Nomascus leucogenys
817206 Arabidopsis thaliana
11651 Mus musculus
207 Homo sapiens
24185 Rattus norvegicus
399170 Xenopus laevis
395928 Gallus gallus
490878 Canis lupus familiaris
100126861 Sus scrofa
280991 Bos taurus
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