Aperçu des produits pour anti-AKT (AKT1) Anticorps

Full name:
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 Anticorps (AKT1)
Chez www.anticorps-enligne.fr sont 1284 V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Anticorps de 45 de différents fournisseurs disponibles. De plus, nous expédions AKT Kits (59) et AKT Protéines (50) et beaucoup plus de produits pour cette protéine. Un total de 1492 AKT produits sont actuellement listés.
Synonymes:
akt, akt-1, Akt/PKB, akt1, ATAKT1, CG4006, CWS6, D-Akt, dakt, dAKT/dPKB, dAkt/PKB, dakt1, DAKT1/PKB, Dmel\\CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, F18A8.2, F18A8_2, K+ transporter 1, l(3)04226, l(3)89Bq, p-Akt, pAkt, PKB, PKB-ALPHA, PKB/Akt, PKB/dAKT, PKBalpha, POTASSIUM TRANSPORTER, PRKBA, Rac, RAC-ALPHA, RacPK, v-akt, v-akt1, xAct
afficher tous les anticorps Gène GeneID UniProt
AKT1 11651 P31750
AKT1 207 P31749
Anti-Rat AKT1 AKT1 24185 P47196

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Tous anti-AKT Anticorps disponible

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anti-AKT Anticorps mieux référencés

  1. Human Polyclonal AKT Primary Antibody pour EIA, IHC (p) - ABIN358075 : Bellacosa, Chan, Ahmed, Datta, Malstrom, Stokoe, McCormick, Feng, Tsichlis: Akt activation by growth factors is a multiple-step process: the role of the PH domain. dans Oncogene 1998 (PubMed)
    Show all 4 references for 358075

  2. Human Polyclonal AKT Primary Antibody pour DB - ABIN389509 : DeBusk, Hallahan, Lin: Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway. dans Experimental cell research 2004 (PubMed)
    Show all 4 references for 389509

  3. Human Polyclonal AKT Primary Antibody pour FACS, WB - ABIN652283 : Liao, Grobholz, Abel, Trojan, Michel, Angel, Mayer: Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer. dans International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 4 references for 652283

  4. Human Polyclonal AKT Primary Antibody pour WB - ABIN389510 : Bourguignon, Singleton, Diedrich et al.: Hyaluronan-CD44 interaction with Rac1-dependent protein kinase N-gamma promotes phospholipase Cgamma1 activation, Ca(2+) signaling, and cortactin-cytoskeleton function leading to keratinocyte ... dans The Journal of biological chemistry 2004 (PubMed)
    Show all 3 references for 389510

  5. Human Polyclonal AKT Primary Antibody pour IF (p), IHC (p) - ABIN725195 : Xu, Huang, Xie, Lin, Guo, Zhuang, Lin, Zhou, Li, Huang, Wei, Man, Zhang: The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients. dans BMC cancer 2013 (PubMed)
    Show all 3 references for 725195

  6. Cow (Bovine) Polyclonal AKT Primary Antibody pour WB - ABIN2792187 : Jones, Jakubowicz, Pitossi, Maurer, Hemmings: Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. dans Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)

  7. Human Polyclonal AKT Primary Antibody pour FACS, IF - ABIN655915 : Chen, Gomes, Monteiro, Wong, Wu, Ng, Karadedou, Millour, Ip, Cheung, Sunters, Chan, Lam, Khoo: Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer. dans PLoS ONE 2010 (PubMed)

Plus d’anticorps contre AKT partenaires d’interaction

Fruit Fly (Drosophila melanogaster) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. The metabolic defects of cycG (Montrer CCNG1 Anticorps) mutant animals are abrogated by a concomitant loss of Wdb, CycG (Montrer CCNG1 Anticorps) presumably influences Akt1 activity at the PP2A (Montrer PPP2R2B Anticorps) nexus; Well rounded (Wrd), another B' subunit of PP2A (Montrer PPP2R2B Anticorps) in Drosophila, binds CycG (Montrer CCNG1 Anticorps) similar to Wdb, and that its loss ameliorates some, but not all, of the metabolic defects of cycG (Montrer CCNG1 Anticorps) mutants.

  2. Our findings demonstrated that lovastatin restored LRRK2 (Montrer LRRK2 Anticorps)-G2019S neurite degeneration by augmenting Akt/NRF2 (Montrer NFE2L2 Anticorps) pathway and inhibiting downstream GSK3b (Montrer GSK3b Anticorps) activity, which decreased phospho-tau levels. We suggested that lovastatin is a potential disease-modifying agent for LRRK2 (Montrer LRRK2 Anticorps)-G2019S parkinsonism.

  3. subtle manipulation of foxo (Montrer FOXO Anticorps) through Akt1 can enhance survival during adverse nutrient conditions in Drosophila.

  4. The developmental delay of these novel Akt1 hypomorphs results in a latent phenotype uncovered by generation of somatic clones

  5. these data show that Drosophila Trbl has a conserved role to bind Akt and block Akt-mediated insulin signaling, and implicate Trib proteins as novel sites of signaling pathway integration that link nutrient availability with cell growth and proliferation

  6. AKT1 and caspase-dependent regulation of Acn stability adjusts basal autophagy levels.

  7. Akt1 governs two critical elements of synapse development, neurotransmitter receptor (Montrer GRIN1 Anticorps) localization, and postsynaptic membrane elaboration

  8. Tsc2 (Montrer TSC2 Anticorps) mutants showed a dramatic decrease in the levels of phosphorylated Akt, and interestingly, Akt mutants phenocopied Tsc2 (Montrer TSC2 Anticorps) mutants, leading to the hypothesis that Tsc2 (Montrer TSC2 Anticorps) and Akt might work via the same genetic pathway to regulate synapse growth.

  9. Hippo signaling not only blocks cell division and promotes apoptosis, but also regulates cellular growth by inhibiting the Akt pathway activity.

  10. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten (Montrer PTEN Anticorps) and microRNA bantam.

Arabidopsis thaliana V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. CIPK23 and AtKC1 exhibit distinct effects; however, they act synergistically and balance K(+) uptake/leakage to modulate AKT1-mediated low potassium responses in Arabidopsis.

  2. results suggest that NO decreases K(+) absorption by promoting the synthesis of vitamin B6 PLP (Montrer FNTA Anticorps), which further represses the activity of K(+) channel (Montrer KCNC4 Anticorps) AKT1 in Arabidopsis.

  3. Examination of the athak5 atakt1 double mutant, revealing novel aspects of an uptake system as yet unidentified by genetic means.

  4. AKT1 is regulated by CIPK23 in guard cells and is involved in water stress responses.

  5. These findings provide further insights into the signaling network consisting of CBL (Montrer CBL Anticorps)-CIPK-PP2C interactions in the activation of the AKT1 channel.

  6. Electrophysiological results showed that AtKC1 inhibited the AKT1-mediated inward K(+) currents and negatively shifted the voltage dependence of AKT1 channels.

  7. AtHAK5 and AKT1 are vital for plant growth and development at low K+ concentrations.

  8. In the range between 0.01 and 0.05 mM K+ AtHAK5 and AtAKT1 are the only contributors to K+ acquisition. At higher K+ concentrations, unknown systems come into operation and participate together with AtAKT1 in low-affinity K+ uptake.

  9. CIPK23 directly phosphorylates the K+ transporter AKT1

  10. Data show that interacting calcium sensors (CBL1 and CBL9) together with CIPK23, but not either alone, activated the AKT1 channel in a Ca(2 (Montrer CA2 Anticorps)+)-dependent manner, connecting the Ca(2 (Montrer CA2 Anticorps)+) signal to K(+) uptake through activation of a K(+) channel (Montrer KCNC4 Anticorps).

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. TSC1 (Montrer TSC1 Anticorps)/TSC2 (Montrer TSC2 Anticorps) complex upregulation of OPN (Montrer SPP1 Anticorps) expression is mediated by transcription factor SOX9 (Montrer SOX9 Anticorps) in an mTOR (Montrer FRAP1 Anticorps)-independent manner. Moreover, ablation of OPN (Montrer SPP1 Anticorps) by deficient TSC1 (Montrer TSC1 Anticorps)/TSC2 (Montrer TSC2 Anticorps) complex contributed to inactivation of AKT in TSC (Montrer SLC12A3 Anticorps) cells

  2. Our results suggest that increasing Akt/ NF-kappaB (Montrer NFKB1 Anticorps) is a crucial mediator of skin aging, which can increase the susceptibility of cell transformation.

  3. findings highlight a pivotal link between an epigenetic regulator, WHSC1, and key intracellular signaling molecules, AKT, RICTOR, and Rac1, to drive prostate cancer metastasis.

  4. Studies indicate that the Pten (Montrer PTEN Anticorps)+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten (Montrer PTEN Anticorps) is a key regulatory player in the PI3K/PTEN (Montrer PTEN Anticorps)/AKT pathway.

  5. a simple, linear, four-compartment ordinary differential equation (ODE) model of Akt activation that tracks both the biochemical state and the physical location of Akt, is reported.

  6. Psgl-1 (Montrer SELPLG Anticorps) deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT axis.

  7. Data show that docetaxel, rapamycin and tanespimycin multi-drug loaded micelles targeted against HSP90 (Montrer HSP90 Anticorps) and the PI3K/AKT/mTOR (Montrer FRAP1 Anticorps) pathway in prostate cancer.

  8. Furthermore, Leishmania RNA virus 1-induced TLR-3 (Montrer TLR3 Anticorps) activation promoted parasite persistence by enhancing macrophage survival through Akt activation in a manner partially dependent on miR (Montrer MLXIP Anticorps)-155.

  9. Collectively, these findings showed that SA suppressed mammary gland development of pubertal mice, which was coincident with the SA-inhibited HC11 (Montrer CCL2 Anticorps) proliferation, and was associated with inhibition of PI3K/Akt signaling pathway through activation of GPR120 (Montrer O3FAR1 Anticorps).

  10. Findings suggest that atorvastatin attenuates diabetes-associated renal injury by reducing reactive oxygen species (ROS (Montrer ROS1 Anticorps)) generation, RhoA (Montrer RHOA Anticorps) activity and normalizing Akt/GSK3beta (Montrer GSK3b Anticorps) signaling pathways.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. High AKT1 expression is associated with melanoma.

  2. PTEN (Montrer PTEN Anticorps) rs701848 and AKT1 rs2494752 polymorphisms might be a candidate pharmacogenomic factor to assess the susceptibility of and response and prognosis prediction for interindividualized CE(A)F chemotherapy in breast cancer patients.

  3. Lysophosphatidylcholine activates the Akt pathway to upregulate extracellular matrix protein production in human aortic valve cells and may contribute to the mechanism of valvular sclerosis associated with the development and progression of aortic stenosis.

  4. Cross-talk between Akt1 and Src (Montrer SRC Anticorps) regulates endothelial-barrier function.

  5. We found statistically significant DNA hypomethylation of the promoter regions of DRD3 (Montrer DRD3 Anticorps) (P = 0.032), DRD4 (Montrer DRD4 Anticorps) (P = 0.05), MB-COMT (Montrer COMT Anticorps) (P = 0.009), and AKT1 (P = 0.0008) associated with increased expression of the corresponding genes in patients with methamphetamine psychosis (P = 0.022, P = 0.034, P = 0.035, P = 0.038, respectively)

  6. High AKT1 expression is associated with T-cell leukemia.

  7. Results indicate that p110alpha (Montrer PIK3CA Anticorps) primarily mediates PI3K (Montrer PIK3CA Anticorps)/AKT signaling in HER2 (Montrer ERBB2 Anticorps)+ PTEN (Montrer PTEN Anticorps) deficient breast tumors whereas p110beta conditionally mediates HER2 (Montrer ERBB2 Anticorps)/PI3K (Montrer PIK3CA Anticorps) signaling in the absence of p110alpha (Montrer PIK3CA Anticorps).

  8. AKT1 mutation is associated with olfactory groove meningiomas.

  9. Activation of stromal MYC (Montrer MYC Anticorps) was critical for this reprogramming and for the sustained cellular responses elicited by LO, both in vitro and in vivo in an AKT1-dependent manner. Inhibition of LO internalization prevented activation of MYC (Montrer MYC Anticorps) and impaired the tumor-supporting properties of fibroblasts.

  10. Cytokines IL-2 (Montrer IL2 Anticorps)/7/9 stimulation activates PI3K (Montrer PIK3CA Anticorps)/Akt pathways downstream of Ras in RasGRP1 (Montrer RASGRP1 Anticorps) T-cell acute lymphoblastic leukemia (T-ALL).

Pig (Porcine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR (Montrer FRAP1 Anticorps)-FOXO1 (Montrer FOXO1 Anticorps) signaling and suppressing the activation of TLR4 (Montrer TLR4 Anticorps) and/or NOD2 (Montrer NOD2 Anticorps) signaling pathways.

  2. Data show that homocysteine (Hcy) can ameliorate the endothelium-independent hypoxic coronary vasoconstriction, in which the inhibition of PI3K/Akt signaling pathway may be involved.

  3. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 could positively regulate lactose synthesis.

  4. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  5. Host PI3K and Akt1 play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  6. Activity of AKT is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  7. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  8. findings show that megalin (Montrer LRP2 Anticorps) is the sensor that determines whether cells will be protected or injured by albumin (Montrer ALB Anticorps); it binds protein kinase B (PKB) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB in the luminal plasma membrane [

  9. protein kinase B (PKB/Akt)was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  10. Akt signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results demonstrate that activation of AKT is required for gonadotropin regulation of CTNNB1 (Montrer CTNNB1 Anticorps) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (Montrer CAV1 Anticorps) scaffolding domain residue phenylalanine 92 modulates Akt signaling

  3. TG2 (Montrer TGM2 Anticorps) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (Montrer GSK3b Anticorps), and NF-kappaB (Montrer NFKB1 Anticorps).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (Montrer NOX1 Anticorps), reactive oxygen species, and PI3-kinase (Montrer PIK3CA Anticorps) in stimulated NO release.

  6. PI3K/Akt and p53 (Montrer TP53 Anticorps) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR (Montrer FRAP1 Anticorps), p70S6K (Montrer RPS6KB1 Anticorps), and ERK1/2 (Montrer MAPK1/3 Anticorps).

  8. Gab1 (Montrer GAB1 Anticorps) tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B and endothelial nitric-oxide synthase (Montrer NOS3 Anticorps) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (Montrer NOS3 Anticorps) phosphorylation and suppresses tumor necrosis factor alpha (Montrer TNF Anticorps)-induced endothelial cell apoptosis by activating AKT1.

  10. prostaglandin F2alpha phosphorylates TSC2 (Montrer TSC2 Anticorps) and activates mTOR (Montrer FRAP1 Anticorps) and ribosomal protein S6 (Montrer RPS6 Anticorps) kinase (Montrer RPS6KB1 Anticorps) signaling in an AKT-independent manner

AKT (AKT1) profil antigène

Antigen Summary

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with AKT (AKT1)

  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) anticorps
  • v-akt murine thymoma viral oncogene homolog 1 (akt1) anticorps
  • CG4006 gene product from transcript CG4006-RA (Akt1) anticorps
  • potassium channel AKT1 (KT1) anticorps
  • thymoma viral proto-oncogene 1 (Akt1) anticorps
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) anticorps
  • akt anticorps
  • akt-1 anticorps
  • Akt/PKB anticorps
  • akt1 anticorps
  • ATAKT1 anticorps
  • CG4006 anticorps
  • CWS6 anticorps
  • D-Akt anticorps
  • dakt anticorps
  • dAKT/dPKB anticorps
  • dAkt/PKB anticorps
  • dakt1 anticorps
  • DAKT1/PKB anticorps
  • Dmel\\CG4006 anticorps
  • dPKB anticorps
  • DRAC-PK anticorps
  • DRAC-PK66 anticorps
  • DRAC-PK85 anticorps
  • F18A8.2 anticorps
  • F18A8_2 anticorps
  • K+ transporter 1 anticorps
  • l(3)04226 anticorps
  • l(3)89Bq anticorps
  • p-Akt anticorps
  • pAkt anticorps
  • PKB anticorps
  • PKB-ALPHA anticorps
  • PKB/Akt anticorps
  • PKB/dAKT anticorps
  • PKBalpha anticorps
  • POTASSIUM TRANSPORTER anticorps
  • PRKBA anticorps
  • Rac anticorps
  • RAC-ALPHA anticorps
  • RacPK anticorps
  • v-akt anticorps
  • v-akt1 anticorps
  • xAct anticorps

Protein level used designations for AKT1

RAC-alpha serine/threonine-protein kinase , protein kinase B , v-akt murine thymoma viral oncogene homolog 1 , Akt kinase , Akt1-PA , Akt1-PB , Akt1-PC , CG4006-PA , CG4006-PB , CG4006-PC , dAkt kinase , related to PKA to PKC protein kinases , related to the A and C kinases , AKT1 kinase , PKB alpha , RAC-PK-alpha , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , proto-oncogene c-Akt , rac protein kinase alpha , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , Akt , protein kinase Akt-1 , protein kinase B, alpha , xAkt , serine/threonine protein kinase , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1

GENE ID SPECIES
100294652 Ovis aries
697747 Macaca mulatta
740898 Pan troglodytes
100101714 Xenopus (Silurana) tropicalis
100490038 Xenopus (Silurana) tropicalis
41957 Drosophila melanogaster
100556289 Anolis carolinensis
100587109 Nomascus leucogenys
817206 Arabidopsis thaliana
11651 Mus musculus
207 Homo sapiens
24185 Rattus norvegicus
399170 Xenopus laevis
395928 Gallus gallus
490878 Canis lupus familiaris
100126861 Sus scrofa
280991 Bos taurus
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