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anti-Human FOXO1 Anticorps:
anti-Rat (Rattus) FOXO1 Anticorps:
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Human Polyclonal FOXO1 Primary Antibody pour ICC, IF - ABIN250693
Hoekstra, Sefton, Berry, Lu, Hardt, Marsh, Yin, Clardy, Chakravarti, Bulun, Kim: Progestins activate the AKT pathway in leiomyoma cells and promote survival. dans The Journal of clinical endocrinology and metabolism 2009
Show all 8 Pubmed References
Human Polyclonal FOXO1 Primary Antibody pour IHC - ABIN966149
Zhao, Gan, Pan, Kan, Majeski, Adam, Unterman: Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms. dans The Biochemical journal 2004
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Human Polyclonal FOXO1 Primary Antibody pour IF, IHC - ABIN362088
Zhan, Wang, Li, Xu, Sun, Xu: Activation of Akt/FoxO signaling pathway contributes to induction of neuroprotection against transient global cerebral ischemia by hypoxic pre-conditioning in adult rats. dans Journal of neurochemistry 2010
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Human Polyclonal FOXO1 Primary Antibody pour IHC (fro), IF - ABIN4948288
Sajan, Ivey, Lee, Mastorides, Jurczak, Samuels, Shulman, Braun, Leitges, Farese: PKC? haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes. dans Molecular endocrinology (Baltimore, Md.) 2014
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Human Polyclonal FOXO1 Primary Antibody pour ICC, IF - ABIN4312363
Sahu, Laakso, Ovaska, Mirtti, Lundin, Rannikko, Sankila, Turunen, Lundin, Konsti, Vesterinen, Nordling, Kallioniemi, Hautaniemi, Jänne: Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer. dans The EMBO journal 2011
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Human Monoclonal FOXO1 Primary Antibody pour ICC, IHC - ABIN969521
Lau, Koty, Nalbantoglu: Differential response of glioma cells to FOXO1-directed therapy. dans Cancer research 2009
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Human Polyclonal FOXO1 Primary Antibody pour IHC - ABIN966148
Gan, Zheng, Chabot, Unterman, Quirion: Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors. dans Journal of neurochemistry 2005
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Human Polyclonal FOXO1 Primary Antibody pour IF, IHC - ABIN362738
Smith, Norton, Gorospe, Jiang, Nemoto, Holbrook, Finkel, Kusiak: Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity. dans The Journal of cell biology 2005
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Human Polyclonal FOXO1 Primary Antibody pour ELISA, WB - ABIN252951
Paik, Kollipara, Chu, Ji, Xiao, Ding, Miao, Tothova, Horner, Carrasco, Jiang, Gilliland, Chin, Wong, Castrillon, DePinho: FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. dans Cell 2007
Cow (Bovine) Polyclonal FOXO1 Primary Antibody pour WB - ABIN2780391
Okamoto, Hribal, Lin, Bennett, Ward, Accili: Role of the forkhead protein FoxO1 in beta cell compensation to insulin resistance. dans The Journal of clinical investigation 2006
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MicroRNA-183-96-182 cluster regulates bovine granulosa cell function by targeting FOXO1 gene.
downregulation of SIRT1 (Montrer SIRT1 Anticorps) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age
FOXO (Montrer FOXO3 Anticorps) is a key regulator of ROS (Montrer ROS1 Anticorps)-induced apoptosis in mammalian cells.
Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (Montrer NCAM1 Anticorps)-1 mRNA.
The results demonstrate pathways through which two different mediators, TNF-alpha (Montrer TNF Anticorps) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.
These data suggest that high doses of insulin (Montrer INS Anticorps) downregulate apoA-I (Montrer APOA1 Anticorps) gene expression in HepG2 cells through redistribution of FOXO1/LXRbeta (Montrer NR1H2 Anticorps) complex, FOXA2 (Montrer FOXA2 Anticorps), and LXRalpha (Montrer NR1H3 Anticorps) on hepatic enhancer of apoA-I (Montrer APOA1 Anticorps) gene.
FOXO1 inhibits the self-renewal capacity of gastric cancer cells through interaction with LGR5 (Montrer LGR5 Anticorps).
elevated expression of microRNA-873 facilitates Th17 differentiation by targeting forkhead box O1 (Foxo1) in the pathogenesis of systemic lupus erythematosus
Results provide a mechanistic understanding for the observation that loss of IGF-1R (Montrer IGF1R Anticorps) expression decreases tamoxifen sensitivity resulting from reduced FoxO1 expression in breast cancer cells.
Low FOXO1 expression is associated with invasive oral cancer.
TLR4 (Montrer TLR4 Anticorps) and C5aR (Montrer C5AR1 Anticorps) crosstalk in dendritic cells induces a core regulatory network of RSK2 (Montrer RPS6KA3 Anticorps), PI3Kbeta, SGK1 (Montrer SGK1 Anticorps), and FOXO (Montrer FOXO3 Anticorps) transcription factors.
The data suggest that pre-B cells are endowed with a protective mechanism that reduces the risk for aberrant recombinations and chromosomal translocations when exposed to DNA damage, involving the ATM (Montrer ATM Anticorps)-dependent regulation of FOXO1 binding to the Erag enhancer region.
expression of Bim (Montrer BCL2L11 Anticorps) is mediated by FoxO1 and indirectly downregulated by thyroid hormone/thyroid hormone (Montrer PTH Anticorps) receptor (Montrer THRA Anticorps), leading to chemotherapy resistance and doxorubicin-promoted metastasis of hepatoma cells.
this study shows that FoxO1 plays an important role in regulating asbestos-induced apoptosis in T cells
increased FOXO1 represents a critical mechanism driving aberrant self-renewal in preleukemic cells expressing the t(8;21)-associated oncogene AML1 (Montrer RUNX1 Anticorps)-ETO (Montrer RUNX1T1 Anticorps).
These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (Montrer AKT1 Anticorps)-mTOR (Montrer FRAP1 Anticorps)-FOXO1 signaling and suppressing the activation of TLR4 (Montrer TLR4 Anticorps) and/or NOD2 (Montrer NOD2 Anticorps) signaling pathways.
let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (Montrer MAP3K1 Anticorps) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.
inhibition of FoxO1 expression level caused by miR (Montrer MYLIP Anticorps)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (Montrer MYLIP Anticorps)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1
Results show that FoxO1 likely regulates MyHC I (Montrer MYH7 Anticorps) negatively and MyHC IIx and MyHC IIb (Montrer MYH4 Anticorps) positively and may play a pivotal role in the determination of muscle fiber type.
Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (Montrer TNFSF10 Anticorps) and Fas ligand FasL (Montrer FASL Anticorps) expression during follicular atresia.
Data show that IL-4 (Montrer IL4 Anticorps) induces upregulation of the junction protein claudin-5 (Montrer CLDN5 Anticorps) in endothelial cells (ECs) through activation of Jak (Montrer JAK3 Anticorps)/STAT6 (Montrer STAT6 Anticorps) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.
FoxO1 and C/EBPb (Montrer CEBPB Anticorps) regulate preadipocyte adipogenesis possibly through C/EBPb (Montrer CEBPB Anticorps)-> FoxO1-> C/EBPb (Montrer CEBPB Anticorps) feedback regulatory loop and FoxO1-C/EBPb (Montrer CEBPB Anticorps) protein complex.
FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.
concluded that PI 3 (Montrer PI3 Anticorps)-kinase and Akt (Montrer AKT1 Anticorps) are activated after renal ischemia/reperfusion and that Akt (Montrer AKT1 Anticorps) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (Montrer FOXO3 Anticorps), which may affect epithelial cell fate in acute renal failure.
FoxO1a can regulate p27kip nuclear localization
data reveal apelin (Montrer APLN Anticorps) as a novel regulator of FoxO1 in cardiac cells and provide evidence for the potential of apelin (Montrer APLN Anticorps)-13 in prevention of apoptosis and mitochondrial damage in conditions combining I/R injury and obesity.
Besides, both in vivo and in votro studies suggested that K145 stimulated insulin (Montrer INS Anticorps) dependent Akt (Montrer AKT1 Anticorps) phosphorylation and subsequently activates FoxO1 phosphorylation therefore inhibited gluconeogenetic genes expression including PEPCK (Montrer PEPCK Anticorps) and G6pase (Montrer G6PC Anticorps). Our study figures out a potential extent increase the value of developing K145 as therapeutic candidate for diabetes.
Ikaros (Montrer IKZF1 Anticorps) is a transcriptional regulator required for maintaining levels of Foxo1 gene expression in naive T-cells.
this study shows that Foxo1 is a positive regulatory factor for the proliferation and activity of Treg cells
Data show that Fos-Related Antigen-2 (Fra-2 (Montrer FOSL2 Anticorps)) is a key upstream regulator of forkhead box O1 (Foxo1) and interferon regulatory factor 4 (Irf4 (Montrer IRF4 Anticorps)) expression and influences proliferation and differentiation of B cells at multiple stages.
ANG2 (Montrer ANGPT2 Anticorps) activation of Tie2 (Montrer TEK Anticorps) supports stable enlargement of normal nonleaky vessels, but reduction of Tie1 (Montrer TIE1 Anticorps) in inflammation leads to ANG2 (Montrer ANGPT2 Anticorps) antagonism of Tie2 (Montrer TEK Anticorps) and initiates a positive feedback loop wherein FOXO1-driven ANG2 (Montrer ANGPT2 Anticorps) expression promotes vascular remodeling and leakage
Link between the antioxidative activity of FoxO1 with PINK1 (Montrer PINK1 Anticorps)/Parkin (Montrer PARK2 Anticorps)-induced mitophagy, indicating a novel role of FoxO1 in diabetic nephropathy.
Pyruvate dehydrogenase kinase 4 (Montrer PDK4 Anticorps) is a direct transcriptional target of FoxO1 in the heart. FoxO1 directly regulates Pdk4 (Montrer PDK4 Anticorps) transcription in the heart, thereby controlling PDH (Montrer PDP Anticorps) activity and subsequent glucose oxidation rates.
the overlap of IR and IGF1R (Montrer IGF1R Anticorps) signaling is critical to the regulation of muscle protein turnover, and this regulation depends on suppression of FoxO (Montrer FOXO3 Anticorps)-regulated, autophagy-mediated protein degradation
These results suggest that the LKB1 (Montrer STK11 Anticorps)-AMPK (Montrer PRKAA1 Anticorps)-FoxO1 signaling pathway is a critical mediator of the antioxidant properties of H2, further supporting the idea that H2 acts as a signaling molecule to serve various physiological functions.
FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (Montrer SOD1 Anticorps) and catalase (Montrer CAT Anticorps) mRNA and protein levels in this organ.
These results indicate that miR (Montrer MYLIP Anticorps)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.
gas6 (Montrer GAS6 Anticorps) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (Montrer AKT1 Anticorps)-dependent inactivation of FOXO1a.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
forkhead box protein O1
, forkhead box protein O1A
, forkhead, Drosophila, homolog of, in rhabdomyosarcoma
, forkhead box O1A
, forkhead box protein O1-A
, fox family transcription factor FoxO1a.1
, foxhead box protein O1-A
, Forkhead box protein O1A
, Forkhead in rhabdomyosarcoma
, forkhead box O1A (rhabdomyosarcoma)
, forkhead box O1a
, forkhead in rhabdomyosarcoma
, forkhead protein 1
, forkhead/winged helix transcription factor FOXO1a
, forkhead box O1
, forkhead box protein O1-like