Aperçu des produits pour anti-MTOR (FRAP1) Anticorps

Full name:
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) Anticorps (FRAP1)
Chez www.anticorps-enligne.fr sont 369 Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Anticorps de 36 de différents fournisseurs disponibles. De plus, nous expédions MTOR Kits (45) et MTOR Protéines (4) et beaucoup plus de produits pour cette protéine. Un total de 433 MTOR produits sont actuellement listés.
Synonymes:
2610315D21Rik, AI327068, flat, FRAP, frap1, FRAP2, RAFT1, RAPT1, tor, wu:fc22h08

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anti-MTOR Anticorps mieux référencés

  1. Human Polyclonal MTOR Primary Antibody pour EIA, IHC (p) - ABIN117909 : Chase, Rao, Hofmann, Chang-Hasnain: 1550 nm high contrast grating VCSEL. dans Optics express 2010 (PubMed)
    Show all 9 references for 117909

  2. Dog (Canine) Polyclonal MTOR Primary Antibody pour EIA, WB - ABIN401320 : McMahon, Choi, Lin, Abraham, Lawrence: The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin. dans Molecular and cellular biology 2002 (PubMed)
    Show all 6 references for 401320

  3. Chicken Monoclonal MTOR Primary Antibody pour IF, WB - ABIN968383 : Alarcon, Cardenas, Heitman: Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast. dans Genes & development 1996 (PubMed)
    Show all 5 references for 968383

  4. Human Polyclonal MTOR Primary Antibody pour IF, IHC (p) - ABIN196962 : Holz, Blenis: Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase. dans The Journal of biological chemistry 2005 (PubMed)
    Show all 4 references for 196962

  5. Human Polyclonal MTOR Primary Antibody pour IF (p), IHC (p) - ABIN676403 : Li, Liu, Wang, Sun, Ding, Sun, Han, Wang: Follistatin could promote the proliferation of duck primary myoblasts by activating PI3K/Akt/mTOR signalling. dans Bioscience reports 2014 (PubMed)
    Show all 4 references for 676403

  6. Human Polyclonal MTOR Primary Antibody pour ELISA, WB - ABIN1532744 : Brown, Albers, Shin, Ichikawa, Keith, Lane, Schreiber: A mammalian protein targeted by G1-arresting rapamycin-receptor complex. dans Nature 1994 (PubMed)
    Show all 3 references for 1532744

  7. Human Polyclonal MTOR Primary Antibody pour ELISA, WB - ABIN1531715 : Onyango, Lubyova, Gardellin, Kurzbauer, Weith: Molecular cloning and expression analysis of five novel genes in chromosome 1p36. dans Genomics 1998 (PubMed)
    Show all 3 references for 1531715

  8. Human Polyclonal MTOR Primary Antibody pour IF (p), IHC (p) - ABIN747158 : Yang, Wang, Wang, Zhang, Zhang, Lu, Wang: mTOR is involved in 17?-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1, and CCNE1. dans Molecular reproduction and development 2015 (PubMed)
    Show all 2 references for 747158

  9. Human Polyclonal MTOR Primary Antibody pour IF, IHC (p) - ABIN390217 : Cao, Dong, Meng, Liu, Liao, Liu: MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3. dans Tumour biology 2015 (PubMed)

  10. Human Polyclonal MTOR Primary Antibody pour IHC, ELISA - ABIN1531910 : Luo, Yoneda, Ohmori, Sasaki, Shimbo, Eto, Kato, Miyano, Kobayashi, Sasahira, Chihara, Kuniyasu: Cancer usurps skeletal muscle as an energy repository. dans Cancer research 2014 (PubMed)

Plus d’anticorps contre MTOR partenaires d’interaction

Horse (Equine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

Human Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. High mTOR expression is associated with melanoma.

  2. Studies indicate that understanding mTOR network circuitry will provide insight into its deregulation in diabetes, cancer, and cardiovascular disease, but modeling in silico to elucidate how insulin (Montrer INS Anticorps) activates mTORC2 (Montrer CRTC2 Anticorps) remains poorly defined.

  3. Mutated MTOR identified in central nervous system germ cell tumors upregulated phosphorylation of the AKT (Montrer AKT1 Anticorps) pathway proteins

  4. Findings demonstrate that the Akt (Montrer AKT1 Anticorps)/mTOR pathway is upregulated in verrucous carcinoma of the oral cavity , indicating a role for this pathway in the development and progression of this malignancy.

  5. IL-37 regulates autophagy in SMMC-7721 and Huh-7 cells via inhibition of the PI3K (Montrer PIK3CA Anticorps)/AKT (Montrer AKT1 Anticorps)/mTOR signaling pathway.

  6. A nutrient-sensitive mTOR/ChREBP (Montrer MLXIPL Anticorps) regulated transcriptional network could be a novel target to improve beta cell survival and glucose homeostasis in diabetes.

  7. Interleukin-37 induces apoptosis and autophagy of SMMC-7721 cells by inhibiting phosphorylation of mTOR.

  8. Abnormal mTOR activity may contribute to chemotherapy resistance, while it may also be effectively targeted via molecular means and/or development of specific pharmacological inhibitors.

  9. CXCR2 (Montrer CXCR2 Anticorps) preferentially supports the maintenance of human pluripotent stem cell characteristics as well as facilitates ectodermal differentiation after the commitment to differentiation, and the mechanism might be associated with mTOR, beta-catenin (Montrer CTNNB1 Anticorps), and hTERT activities.

  10. Data show that mTOR protein forms a complex with Raptor (Montrer RPTOR Anticorps) and estrogen receptor-alpha (ERalpha (Montrer ESR1 Anticorps)).

Mouse (Murine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. results establish a novel mechanism by which mTORC1 regulates Th1 differentiation, through control of T-bet phosphorylation

  2. Tsc2 (Montrer TSC2 Anticorps)-mTOR signaling in mesenchyme is essential for the maintenance of renal structure and for lung alveolarization.

  3. This study suggests that mTOR activity in hepatocytes decreases hepatic vulnerability to injury through a mechanism dependent on NF-kappaB (Montrer NFKB1 Anticorps) proinflammatory cytokine signaling pathway in both normal and steatotic liver.

  4. TSC1 (Montrer TSC1 Anticorps)/TSC2 (Montrer TSC2 Anticorps) complex upregulation of OPN (Montrer SPP1 Anticorps) expression is mediated by transcription factor SOX9 (Montrer SOX9 Anticorps) in an mTOR-independent manner. Moreover, ablation of OPN (Montrer SPP1 Anticorps) by deficient TSC1 (Montrer TSC1 Anticorps)/TSC2 (Montrer TSC2 Anticorps) complex contributed to inactivation of AKT (Montrer AKT1 Anticorps) in TSC (Montrer SLC12A3 Anticorps) cells

  5. Suppressing mTOR signaling in in vitro-expanded Vgamma4 gammadelta T cells via the mechanistic inhibitor rapamycin enhanced their cytotoxicity against multiple tumor cell lines, and these cells performed better tumor-suppressing effects upon adoptive therapy. mTOR signaling plays an important role in the cytotoxic effector function of gammadelta T cells.

  6. A nutrient-sensitive mTOR/ChREBP (Montrer MLXIPL Anticorps) regulated transcriptional network could be a novel target to improve beta cell survival and glucose homeostasis in diabetes.

  7. Mycobacterium ulcerans mycolactone acts as an inhibitor of the mechanistic Target of Rapamycin (mTOR) signaling pathway by interfering with the assembly of the two distinct mTOR protein complexes mTORC1 and mTORC2 (Montrer CRTC2 Anticorps)

  8. High mTOR expression is associated with pituitary tumor development.

  9. mTOR protein signaling promotes stable epidermal adhesion in the skin and accelerates wound healing.

  10. mTOR-sensitive perturbation of smooth muscle cell mechanosensing contributes to elastin (Montrer ELN Anticorps) aortopathy.

Zebrafish Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. This study reveals the dramatic rescue effects of L-leucine stimulation of mTORC1 in RBS (Montrer ESCO2 Anticorps) cells and supports that normal gene expression and translation requires ESCO2 (Montrer ESCO2 Anticorps) function.

  2. By inhibiting mTOR signaling via Fbxw7 (Montrer FBXW7 Anticorps), the amount of myelination during development is reduced.

  3. Apc mutations activate mechanistic target of rapamycin complex 1 in mice and zebrafish

  4. In our zebrafish model, autophagy induction does not depend on inhibition of the Tor pathway or activation of Tp53 (Montrer TP53 Anticorps).

  5. TOR signaling is a common pathological pathway that can be leveraged for therapeutic benefits in cardiomyopathies of different origins.

  6. in addition to regulating cell growth and proliferation, TOR signaling controls the developmental program guiding epithelial morphogenesis in the intestine

Pig (Porcine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. The immunoprecipitation results also showed that high AA concentrations significantly increased the interaction of mTOR and PPARg (Montrer PPARG Anticorps). In summary, PPARg (Montrer PPARG Anticorps) plays an important role in the regulation of IGF-1 (Montrer IGF1 Anticorps) secretion and gene expression in response to dietary protein.

  2. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (Montrer AKT1 Anticorps)-mTOR-FOXO1 (Montrer FOXO1 Anticorps) signaling and suppressing the activation of TLR4 (Montrer TLR4 Anticorps) and/or NOD2 (Montrer NOD2 Anticorps) signaling pathways.

  3. Data show that the amount of proteins related to mechanistic target of rapamycin (mTOR) signaling pathways decreased along crypt-villus axis (CVA).

  4. AMPK (Montrer PRKAA1 Anticorps)-mTOR-autophagy signaling is altered by intrauterine growth restriction in newborn piglets.

  5. Uroguanylin (Montrer GUCA2B Anticorps) modulates (Na++K+)ATPase (Montrer ATP1A1 Anticorps) in a proximal tubule cells via cGMP/protein kinase (Montrer CDK7 Anticorps) G, cAMP/protein kinase A, and mTOR pathways.

  6. mTOR is involved in 17beta-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1 (Montrer CCND1 Anticorps), and CCNE1 (Montrer CCNE1 Anticorps).

  7. L-Glutamine (Montrer GFPT2 Anticorps) enhances enterocyte growth via activation of the mTOR.

  8. Arg, Leu, and Gln act coordinately to stimulate proliferation of pTr (Montrer PTCHD3 Anticorps) cells through activation of the MTOR-RPS6K-RPS6 (Montrer RPS6 Anticorps)-EIF4EBP1 (Montrer EIF4EBP1 Anticorps) signal transduction pathway.

  9. Data indicate that the expression of MAP1LC3A (Montrer MAP1LC3A Anticorps), B and autophagy-associated genes (ATG5 (Montrer ATG5 Anticorps), mTOR, Beclin-1 (Montrer BECN1 Anticorps)) was increased in normal pigs, while decreased in miniature pigs.

  10. Biochemical, cellular, and molecular data suggest that L-arginine (Montrer GATM Anticorps) stimulates mTOR biosynthesis, mTOR signaling, and overall protein biosynthesis/turnover in placental/trophoblast and blastocyst/ectoderm cells thereby enhancing cell proliferation.

Cow (Bovine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. These findings suggest that mTOR is involved in the control of the expression of multiple genes in cattle, which may be triggered by the luteinizing hormone surge.

  2. 14-3-3gamma (Montrer YWHAG Anticorps) affects mTOR protein pathway and regulates lactogenesis in dairy cow mammary epithelial cells.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2 (Montrer JAK2 Anticorps)-STAT5 (Montrer STAT5A Anticorps) and mTOR signaling pathways.

  4. Insulin (Montrer INS Anticorps)-induced activation of phosphoinositide 3-kinase~mTOR pathway up-regulates tau protein via acceleration of protein synthesis in adrenal chromaffin cells, promoting neurite-like process outgrowth.

  5. IGF-I (Montrer IGF1 Anticorps) down-regulated functional IGF-I receptor (Montrer IGF1R Anticorps) via GSK-3beta (Montrer GSK3b Anticorps) inhibition and mTOR activation; constitutive activity of GSK-3beta (Montrer GSK3b Anticorps) maintained IGF-I receptor (Montrer IGF1R Anticorps) level in nonstimulated cells.

  6. stimulation of mammary protein synthesis by amino acids and its enhancement by a combination of the lactogenic hormones hydrocortisone, insulin (Montrer INS Anticorps), and prolactin (Montrer PRL Anticorps) were associated with increased phosphorylation of the mTOR substrates

  7. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (Montrer AKT1 Anticorps), mTOR, p70S6K (Montrer RPS6KB1 Anticorps), and ERK1/2 (Montrer MAPK1/3 Anticorps).

  8. prostaglandin F2alpha phosphorylates TSC2 (Montrer TSC2 Anticorps) and activates mTOR and ribosomal protein S6 (Montrer RPS6 Anticorps) kinase (Montrer RPS6KB1 Anticorps) signaling in an AKT (Montrer AKT1 Anticorps)-independent manner

  9. mTOR links IGF-I (Montrer IGF1 Anticorps) and EGF (Montrer EGF Anticorps) signaling in inhibiting the autophagy pathways.

MTOR (FRAP1) profil antigène

Antigen Summary

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Alternative names and synonyms associated with MTOR (FRAP1)

  • mechanistic target of rapamycin (serine/threonine kinase) (MTOR) anticorps
  • mechanistic target of rapamycin (serine/threonine kinase) (Mtor) anticorps
  • mechanistic target of rapamycin (serine/threonine kinase) (mtor) anticorps
  • 2610315D21Rik anticorps
  • AI327068 anticorps
  • flat anticorps
  • FRAP anticorps
  • frap1 anticorps
  • FRAP2 anticorps
  • RAFT1 anticorps
  • RAPT1 anticorps
  • tor anticorps
  • wu:fc22h08 anticorps

Protein level used designations for FRAP1

FK506 binding protein 12-rapamycin associated protein 1 , FK506 binding protein 12-rapamycin associated protein 2 , FK506-binding protein 12-rapamycin complex-associated protein 1 , FKBP-rapamycin associated protein , FKBP12-rapamycin complex-associated protein 1 , mammalian target of rapamycin , rapamycin and FKBP12 target 1 , rapamycin associated protein FRAP2 , rapamycin target protein 1 , serine/threonine-protein kinase mTOR , FKBP-rapamycin associated protein (FRAP) , FKBP-rapamycin-associated protein FRAP , FKBP12-rapamycin complex-associated protein , angiopoietin-like factor CDT6 , RAPT1 , rapamycin and FKBP12 target-1 protein , target of rapamycin

GENE ID SPECIES
100051341 Equus caballus
419455 Gallus gallus
2475 Homo sapiens
56717 Mus musculus
56718 Rattus norvegicus
324254 Danio rerio
478232 Canis lupus familiaris
100127359 Sus scrofa
100139219 Bos taurus
100860902 Capra hircus
100271659 Ovis aries
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