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Aperçu des produits pour anti-PIK3CA (PIK3CA) Anticorps

Full name:
anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide Anticorps (PIK3CA)
Chez www.anticorps-enligne.fr sont 154 Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) Anticorps de 27 de différents fournisseurs disponibles. De plus, nous expédions PIK3CA Kits (8) et PIK3CA Protéines (3) et beaucoup plus de produits pour cette protéine. Un total de 174 PIK3CA produits sont actuellement listés.
Synonymes:
6330412C24Rik, C-P3K, caPI3K, CLOVE, CWS5, MCAP, MCM, MCMTC, p110, p110-alpha, p110alpha, pi3-k, PI3-kinase, PI3K, PI3K-alpha
afficher tous les anticorps Gène GeneID UniProt
PIK3CA 18706 P42337
PIK3CA 5290 P42336
PIK3CA 170911  

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anti-PIK3CA Anticorps mieux référencés

  1. Human Monoclonal PIK3CA Primary Antibody pour IF, WB - ABIN968518 : Funaki, Katagiri, Kanda, Anai, Nawano, Ogihara, Inukai, Fukushima, Ono, Yazaki, Kikuchi, Oka, Asano: p85/p110-type phosphatidylinositol kinase phosphorylates not only the D-3, but also the D-4 position of the inositol ring. dans The Journal of biological chemistry 1999 (PubMed)
    Show all 5 references for ABIN968518

  2. Chicken Monoclonal PIK3CA Primary Antibody pour BI, IP - ABIN967707 : Cantley, Auger, Carpenter, Duckworth, Graziani, Kapeller, Soltoff: Oncogenes and signal transduction. dans Cell 1991 (PubMed)
    Show all 5 references for ABIN967707

  3. Human Polyclonal PIK3CA Primary Antibody pour EIA, IHC (p) - ABIN4620510 : Broderick, Di, Parrett, Samuels, Cummins, McLendon, Fults, Velculescu, Bigner, Yan: Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas. dans Cancer research 2004 (PubMed)
    Show all 4 references for ABIN4620510

  4. Human Monoclonal PIK3CA Primary Antibody pour ICC, FACS - ABIN969555 : Edwards, Witherspoon, Wang, Afrasiabi, Pham, Birnbaumer, Lipkin: Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer. dans Cancer research 2009 (PubMed)
    Show all 3 references for ABIN969555

  5. Human Polyclonal PIK3CA Primary Antibody pour FACS, IHC (p) - ABIN1882113 : Singh, Reddy, Goberdhan, Walsh, Dao, Ngai, Chou, O-Charoenrat, Levine, Rao, Stoffel: p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas. dans Genes & development 2002 (PubMed)
    Show all 3 references for ABIN1882113

  6. Human Polyclonal PIK3CA Primary Antibody pour IHC (p), WB - ABIN392560 : Shayesteh, Lu, Kuo, Baldocchi, Godfrey, Collins, Pinkel, Powell, Mills, Gray: PIK3CA is implicated as an oncogene in ovarian cancer. dans Nature genetics 1999 (PubMed)
    Show all 3 references for ABIN392560

  7. Human Polyclonal PIK3CA Primary Antibody pour EIA, WB - ABIN360221 : Zhao, Vogt: Class I PI3K in oncogenic cellular transformation. dans Oncogene 2008 (PubMed)
    Show all 3 references for ABIN360221

  8. Human Monoclonal PIK3CA Primary Antibody pour EIA, FACS - ABIN1108651 : Hwang, Ryu, Chung, Kim, Park, Chae, Chae, Kwon: Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1. dans Oncogene 2004 (PubMed)
    Show all 2 references for ABIN1108651

  9. Human Polyclonal PIK3CA Primary Antibody pour FACS, IF (p) - ABIN677198 : Paul-Samojedny, Suchanek, Borkowska, Pude?ko, Owczarek, Kowalczyk, Machnik, Fila-Dani?ow, Kowalski: Knockdown of AKT3 (PKB?) and PI3KCA suppresses cell viability and proliferation and induces the apoptosis of glioblastoma multiforme T98G cells. dans BioMed research international 2014 (PubMed)

  10. Cow (Bovine) Polyclonal PIK3CA Primary Antibody pour EIA, IHC (p) - ABIN375147 : Abubaker, Bavi, Al-Haqawi, Jehan, Munkarah, Uddin, Al-Kuraya: PIK3CA alterations in Middle Eastern ovarian cancers. dans Molecular cancer 2009 (PubMed)

Plus d’anticorps contre PIK3CA partenaires d’interaction

Mouse (Murine) Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) interaction partners

  1. p110beta has a role in mediating skeletal muscle metabolic signaling by regulating expression of AMP-activated protein kinase (Montrer PRKAA2 Anticorps)

  2. The mRNA levels of leptin (Montrer LEP Anticorps) and of 17-beta-dehydrogenase 3, and enzyme important for testosterone production, were significantly higher in the testis of adult alpha-/- males( PI3K catalytic subunit p110alpha deletion).

  3. Results suggest a role of ST6GalNAc I (Montrer ST6GALNAC1 Anticorps) in promoting the growth and invasion of hepatocarcinoma cells through regulating PI3K/AKT (Montrer AKT1 Anticorps)/NF-kappa B (Montrer NFKB1 Anticorps) signaling, and ST6GalNAc I (Montrer ST6GALNAC1 Anticorps) might be a marker for the prognosis and therapy of hepatocarcinoma.

  4. PI3K signaling plays a modulatory role in the regulation of the transcriptional rhythm of the Dbp (Montrer GC Anticorps) gene by targeting BMAL1 (Montrer ARNTL Anticorps) and CLOCK.

  5. Analysis of 18 signalling signatures revealed that PI3K signalling is significantly induced whereas EGFR (Montrer EGFR Anticorps) signalling is significantly reduced in Pten (Montrer PTEN Anticorps)() versus PIK3CA(H1047R) tumors. Thus, Pten (Montrer PTEN Anticorps)() and PIK3CA(H1047R) tumors exhibit discernable differences that may impact tumorigenesis and response to therapy.

  6. activating PIK3CA mutations gives rise to sporadic venous malformations in mice, which closely resemble the histology of the human disease.

  7. These data demonstrate a causal relationship between activating Pik3ca mutations and the genesis of vascular malformations.

  8. data demonstrate that the PI3K p110alpha-Akt (Montrer AKT1 Anticorps)/Rac1 and NOX1 (Montrer NOX1 Anticorps) signalling pathways play a pivotal role in VEGF (Montrer VEGFA Anticorps)-induced vascular differentiation and cell migration.

  9. miR (Montrer MLXIP Anticorps)-490-5p functions as a tumour suppressor in renal carcinoma (Montrer TSC2 Anticorps) by targeting PIK3CA

  10. Thus, non-canonical phosphoinositide 3-kinase-antagonism by Itpkb (Montrer ITPKB Anticorps) restricts pre-T cell receptor (Montrer PTCRA Anticorps) induced metabolic activation to enforce coincidence-detection of pre-T cell receptor (Montrer PTCRA Anticorps) expression and Notch (Montrer NOTCH1 Anticorps)-engagement.

Human Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) interaction partners

  1. The expression of ribosomal and proteasomal components was significantly up-regulated in primary human colorectal tumors harboring PI3K pathway activation

  2. We revealed that activation of the PI3K/Akt (Montrer AKT1 Anticorps) pathway was the main cause of impaired autophagy in ELK3 (Montrer ELK3 Anticorps) KD. Our results suggest that targeting ELK3 (Montrer ELK3 Anticorps) may be a potential approach to overcome doxorubicin resistance in breast cancer therapeutics.

  3. CLOVES syndrome is an overgrowth syndrome caused by mosaic activating mutation in phosphoinositide-3-kinase, catalytic, alpha polypeptide (Montrer ITGAE Anticorps) (PIK3CA) gene.

  4. Data indicated next-generation sequencing (NGS) for the identification of somatic variation in the phosphoinositide-3-kinase, catalytic, alpha polypeptide (Montrer ITGAE Anticorps) (PIK3CA)-related overgrowth spectrum (PROS) among 14 patients submitted for clinical testing.

  5. Our data indicate that, similar to other benign proliferative lesions occurring in the breast parenchyma, activating PIK3CA mutations are very common in nipple adenomas

  6. Study identified PIK3CA mutation as an independent prognostic factor in patients who underwent APR (Montrer LRP1 Anticorps) for ASCC recurrence.

  7. Data show that acid sensing ion channel (Montrer ACCN2 Anticorps) 1a (ASIC1a (Montrer ACCN2 Anticorps)) mediated calcium influx, which resulted in the activation of PI3K/AKT (Montrer AKT1 Anticorps) signaling and increased drug resistance, suggesting that ASIC1a (Montrer ACCN2 Anticorps)/Ca(2 (Montrer CA2 Anticorps)+)/PI3K/AKT (Montrer AKT1 Anticorps) signaling represents a pathway that regulates drug resistance, thus offering a potential target for chemotherapy of hepatocellular carcinoma (HCC (Montrer FAM126A Anticorps)).

  8. Data, including data from hydrogen/deuterium exchange mass spectrometry studies using full-length constructs for both catalytic/p110alpha and regulatory/p85alpha subunits of phosphoinositide 3-kinase isoform, suggest that the catalytic subunit exhibits binding sites for four inhibitor compounds studied, including a low-affinity binding site for CAL (Montrer FBLIM1 Anticorps)-101.

  9. Bis (Montrer BAG3 Anticorps)(acetylacetonato)-oxidovanadium(IV) and sodium metavanadate induced the activation of both PI3K/AKT (Montrer AKT1 Anticorps) and MAPK/ERK (Montrer MAPK1 Anticorps) signaling pathways dose- and time-dependently.

  10. PIK3CA and AKT1 (Montrer AKT1 Anticorps) are frequently mutated in Hidradenoma papilliferum (HP) tumours (29% and 14%, respectively). PIK3CA/AKT1 (Montrer AKT1 Anticorps) pathway alterations in HP further support the hypothesis that HP is the vulvar (anogenital mammary-like gland) analogue of breast intraductal papilloma.

Cow (Bovine) Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) interaction partners

  1. There are multiple conformations in equilibrium during the course of PI3K SH3 domain (Montrer ITSN1 Anticorps) unfolding.

  2. PI3K has a role in activation of 5'-AMP (Montrer TMPRSS5 Anticorps)-activated kinase during hypoxia-reoxygenation of bovine aortic endothelial cells

  3. Production of PtdIns3P by PI3K-C2alpha (Montrer PIK3C2A Anticorps) is required for acquisition of fusion competence in neurosecretion.

  4. crystallographic and biochemical approaches used to gain insight into activating mutations in two noncatalytic p110alpha domains-the adaptor-binding and the helical domains

PIK3CA profil antigène

Antigen Summary

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.

Alternative names and synonyms associated with PIK3CA

  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA) anticorps
  • Phosphoinositide-3-kinase, catalytic, alpha polypeptide (GL50803_14855) anticorps
  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (pik3ca) anticorps
  • phosphoinositide-3-kinase, catalytic, alpha polypeptide (LOC100337822) anticorps
  • phosphatidylinositol 3-kinase, catalytic, alpha polypeptide (Pik3ca) anticorps
  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (Pik3ca) anticorps
  • phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA) anticorps
  • 6330412C24Rik anticorps
  • C-P3K anticorps
  • caPI3K anticorps
  • CLOVE anticorps
  • CWS5 anticorps
  • MCAP anticorps
  • MCM anticorps
  • MCMTC anticorps
  • p110 anticorps
  • p110-alpha anticorps
  • p110alpha anticorps
  • pi3-k anticorps
  • PI3-kinase anticorps
  • PI3K anticorps
  • PI3K-alpha anticorps

Protein level used designations for PIK3CA

phosphoinositide-3-kinase, catalytic, alpha polypeptide , Phosphoinositide-3-kinase, catalytic, alpha polypeptide , PI3-kinase subunit alpha , PI3K-alpha , PI3Kalpha , phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha , phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform , phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha , phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform , phosphoinositide-3-kinase catalytic alpha polypeptide , ptdIns-3-kinase subunit alpha , ptdIns-3-kinase subunit p110-alpha , serine/threonine protein kinase PIK3CA , PI3-kinase p110 subunit alpha , phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha , phosphatidylinositol 3-kinase, catalytic, alpha polypeptide , phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform , PI3K , p110alpha , ptdIns-3-kinase p110 , phosphoinositide 3-kinase catalytic subunit

GENE ID SPECIES
460858 Pan troglodytes
5702156 Giardia lamblia ATCC 50803
100144924 Xenopus (Silurana) tropicalis
100229768 Taeniopygia guttata
100337822 Oryctolagus cuniculus
18706 Mus musculus
5290 Homo sapiens
282306 Bos taurus
170911 Rattus norvegicus
488084 Canis lupus familiaris
424971 Gallus gallus
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