Aperçu des produits pour anti-PPP2R4 (PPP2R4) Anticorps

Full name:
anti-Protein Phosphatase 2A Activator, Regulatory Subunit 4 Anticorps (PPP2R4)
Chez www.anticorps-enligne.fr sont 69 Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) Anticorps de 20 de différents fournisseurs disponibles. De plus, nous expédions PPP2R4 Protéines (9) et PPP2R4 Kits (8) et beaucoup plus de produits pour cette protéine. Un total de 92 PPP2R4 produits sont actuellement listés.
Synonymes:
2610042B21Rik, 6330556D22Rik, C77440, N28142, PP2A, PR53, PR65, PTPA, PTPRA

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anti-Mouse (Murine) PPP2R4 Anticorps:

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anti-PPP2R4 Anticorps mieux référencés

  1. Human Monoclonal PPP2R4 Primary Antibody pour EIA, FACS - ABIN1108715 : Yoon, Jun, Park, Jun Yoo, Moon, Soon Baik, Kim, Kim, Kim, Koh, Taek Lee, You: Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal. dans Stem cells (Dayton, Ohio) 2010 (PubMed)
    Show all 2 references for 1108715

  2. Human Monoclonal PPP2R4 Primary Antibody pour ICC, FACS - ABIN969557 : Singh, Ye, Bucur, Zhu, Tanya Santos, Rabinovitz, Wei, Gao, Hahn, Khosravi-Far: Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT. dans Molecular biology of the cell 2010 (PubMed)
    Show all 2 references for 969557

  3. Human Monoclonal PPP2R4 Primary Antibody pour IP, WB - ABIN1042656 : Fellner, Lackner, Hombauer, Piribauer, Mudrak, Zaragoza, Juno, Ogris: A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo. dans Genes & development 2003 (PubMed)

  4. Human Polyclonal PPP2R4 Primary Antibody pour ELISA, WB - ABIN4347103 : Gushiken, Patel, Liu, Pradhan, Bergeron, Peng, Vijayan: Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling. dans The Journal of biological chemistry 2008 (PubMed)

Plus d’anticorps contre PPP2R4 partenaires d’interaction

Mouse (Murine) Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) interaction partners

  1. data indicate that PTPalpha (Montrer PTPRA Anticorps) and FAK (Montrer PTK2 Anticorps), which are enriched in FAs (Montrer FAS Anticorps), interact with IP3R1 (Montrer ITPR1 Anticorps) at adjacent ER sites to spatially sequester IL-1 (Montrer IL1A Anticorps)-induced Ca(2 (Montrer CA2 Anticorps)+) signalling

  2. oocyte-specific deletion of Ppp2r1a (Montrer PPP2R1A Anticorps) led to severe female subfertility without affecting follicle survival, growth, and ovulation.

  3. A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells.

  4. PP2A (Montrer PPP2R2B Anticorps) (Protein Phosphatase 2A(Twins)) counteracts Plk4 (Montrer PLK4 Anticorps) autophosphorylation, thus stabilizing Plk4 (Montrer PLK4 Anticorps) and promoting centriole duplication

  5. PP2A (Montrer PPP2R2B Anticorps)-A alpha transcriptional regulation is mediated by multiple factors including AP-2alpha (Montrer TFAP2A Anticorps), CREB (Montrer CREB1 Anticorps), ETS-1 (Montrer ETS1 Anticorps), and SP-1 (Montrer SP1 Anticorps)

  6. Data show that DSB promote PP2A to associate with Ku 70 and Ku 86.

  7. protein phosphatase 2A overexpression in NIH 3T3 cells

  8. T-cell receptor (TCR)-dependent tyrosine phosphorylation may be the mechanism by which the regulatory subunit of PP2A (Montrer PPP2R2B Anticorps) prevents the inhibitory function of CTLA-4 (Montrer CTLA4 Anticorps), before TCR-CTLA-4 (Montrer CTLA4 Anticorps) coligation.

  9. PP-2A regulation of paxillin (Montrer PXN Anticorps) phosphorylation may have a role in controlling tumor cell adherence and motility.

  10. PP2A (Montrer PPP2R2B Anticorps) may contribute to melanoma cell radioresistance: the truncated isoform of the PP2A (Montrer PPP2R2B Anticorps) B56gamma regulatory subunit reduces irradiation-induced Mdm2 (Montrer MDM2 Anticorps) phosphorylation

Human Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4) interaction partners

  1. The results of this study demonstrated that HBx of hepatitis B virus impairs interferon (Montrer IFNA Anticorps) signaling via increased expression of SOCS3 (Montrer SOCS3 Anticorps) and PP2A.

  2. The current study describes a novel pathogenic mechanism of action for human polyomavirus 6 small tumor (sT) antigen which involves binding to protein phosphatase 2A (PP2A) via its WFG motif and zinc binding sites for activation of PP2A's downstream oncogenic pathways (MEK (Montrer MAP2K1 Anticorps)/ERK (Montrer EPHB2 Anticorps)/c-Jun (Montrer JUN Anticorps)).

  3. The aim of this review is to shed light on the role of four different phosphatases (PTEN (Montrer PTEN Anticorps), PP2A, CDC25 (Montrer RASGRF1 Anticorps) and DUSP1 (Montrer DUSP1 Anticorps)) in five different solid tumors (breast cancer, lung cancer, pancreatic cancer, prostate cancer and ovarian cancer), in order to better understand the most frequent and aggressive primary cancer of the central nervous system, glioblastoma.

  4. Oncoprotein CIP2A (Montrer KIAA1524 Anticorps) is stabilized via interaction with tumor suppressor PP2A/B56

  5. Such effect by miR (Montrer MLXIP Anticorps)-429 was again abolished with AMPKalpha1 (Montrer PRKAA1 Anticorps) silence or mutation. Together, we propose that PP2A-c silence by miR (Montrer MLXIP Anticorps)-429 activates AMPK (Montrer PRKAA1 Anticorps) and protects osteoblastic cells from Dex.

  6. PTPalpha (Montrer PTPRA Anticorps) is identified as a novel substrate of N-Acetylglucosaminyltransferase V (GnT-V (Montrer MGAT5 Anticorps)) and could be a factor regulating promotion of migration in breast cancer cells

  7. This article reviews the involvement of PP2A in the regulation of three cell signaling pathways: wnt (Montrer WNT2 Anticorps), mTOR (Montrer FRAP1 Anticorps) and MAP kinase (Montrer MAPK1 Anticorps), as well as the G1-->S transition, DNA synthesis and mitotic initiation. These processes are all crucial for proper cell survival and proliferation and are often deregulated in cancer and other diseases. [review]

  8. PP2A-B55 (Montrer MINK1 Anticorps) substrates were identified and assigned their temporal order in mitotic exit.

  9. Our results provide a novel mechanistic insight into the activation of Myc (Montrer MYC Anticorps) by 27-HC via transcriptional repression of PP2A, SCP1 (Montrer SYCP1 Anticorps) and FBW7 (Montrer FBXW7 Anticorps) to increase Myc (Montrer MYC Anticorps) protein stability in breast cancer cells.

  10. Data show that the truncation promotes glycogen synthase kinase-3beta (GSK-3beta (Montrer GSK3b Anticorps)) nuclear translocation and enhances its interaction with protein phosphatase 2A (PP2A), leading to dephosphorylation.

PPP2R4 profil antigène

Antigen Summary

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with PPP2R4

  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform (Ppp2r1a) anticorps
  • protein phosphatase 2A activator, regulatory subunit 4 (PPP2R4) anticorps
  • protein phosphatase 2A, regulatory subunit B (PR 53) (Ppp2r4) anticorps
  • 2610042B21Rik anticorps
  • 6330556D22Rik anticorps
  • C77440 anticorps
  • N28142 anticorps
  • PP2A anticorps
  • PR53 anticorps
  • PR65 anticorps
  • PTPA anticorps
  • PTPRA anticorps

Protein level used designations for PPP2R4

PP2A subunit A isoform PR65-alpha , PP2A subunit A isoform R1-alpha , protein phosphatase PP2A , serine/threonine protein phosphatase A subunit type 2A , serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform , PP2A phosphatase activator , PP2A subunit B' isoform PR53 , phosphotyrosyl phosphatase activator , protein phosphatase 2A, regulatory subunit B' (PR 53) , serine/threonine-protein phosphatase 2A activator , serine/threonine-protein phosphatase 2A regulatory subunit B' , PP2A, subunit B', PR53 isoform , PTPA , serine/threonine-protein phosphatase 2A regulatory subunit 4 , protein tyrosine phosphatase, receptor type, A

GENE ID SPECIES
51792 Mus musculus
5524 Homo sapiens
514460 Bos taurus
100009404 Oryctolagus cuniculus
110854 Mus musculus
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