Aperçu des produits pour anti-AXL (AXL) Anticorps

Full name:
anti-AXL Receptor tyrosine Kinase Anticorps (AXL)
Chez www.anticorps-enligne.fr sont 295 AXL Receptor tyrosine Kinase (AXL) Anticorps de 26 de différents fournisseurs disponibles. De plus, nous expédions AXL Kits (30) et AXL Protéines (20) et beaucoup plus de produits pour cette protéine. Un total de 362 AXL produits sont actuellement listés.
Synonymes:
AI323647, Ark, JTK11, Tyro7, Ufo

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anti-Human AXL Anticorps:

anti-Mouse (Murine) AXL Anticorps:

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anti-AXL Anticorps mieux référencés

  1. Human Polyclonal AXL Primary Antibody pour FACS, IHC (p) - ABIN391878 : Lee, Strunk, Spritz: A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes. dans Oncogene 1993 (PubMed)
    Show all 4 references for 391878

  2. Human Polyclonal AXL Primary Antibody pour EIA, WB - ABIN359786 : Janssen, Schulz, Steenvoorden, Schmidberger, Strehl, Ambros, Bartram: A novel putative tyrosine kinase receptor with oncogenic potential. dans Oncogene 1991 (PubMed)
    Show all 4 references for 359786

  3. Human Polyclonal AXL Primary Antibody pour EIA, WB - ABIN359784 : OBryan, Frye, Cogswell, Neubauer, Kitch, Prokop, Espinosa, Le Beau, Earp, Liu: axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase. dans Molecular and cellular biology 1991 (PubMed)
    Show all 4 references for 359784

  4. Human Polyclonal AXL Primary Antibody pour FACS, IHC (p) - ABIN391876 : Partanen, Mäkelä, Alitalo, Lehväslaiho, Alitalo: Putative tyrosine kinases expressed in K-562 human leukemia cells. dans Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 4 references for 391876

  5. Human Monoclonal AXL Primary Antibody pour FACS - ABIN4895642 : Zheng, Hedl, Abraham: TAM receptor-dependent regulation of SOCS3 and MAPKs contributes to proinflammatory cytokine downregulation following chronic NOD2 stimulation of human macrophages. dans Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

  6. Human Monoclonal AXL Primary Antibody pour FACS - ABIN4895644 : Yumoto, Eber, Wang, Cackowski, Decker, Lee, Nobre, Aguirre-Ghiso, Jung, Taichman: Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow. dans Scientific reports 2016 (PubMed)

  7. Mouse (Murine) Monoclonal AXL Primary Antibody pour FACS - ABIN4899408 : Fujimori, Grabiec, Kaur, Bell, Fujino, Cook, Svedberg, MacDonald, Maciewicz, Singh, Hussell: The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung. dans Mucosal immunology 2015 (PubMed)

Plus d’anticorps contre AXL partenaires d’interaction

Human AXL Receptor tyrosine Kinase (AXL) interaction partners

  1. we identify PROS1 (Montrer PROS1 Anticorps) as a driver of Oral Squamous Cell Carcinoma tumor growth and a modulator of AXL expression

  2. Studies indicate that aberrant AXL receptor tyrosine kinase (AXL) signaling and development of an epithelial-to-mesenchymal transition (EMT (Montrer ITK Anticorps)) phenotype underlie resistance of anaplastic lymphoma kinase (ALK (Montrer ALK Anticorps) F1174L)-driven neuroblastoma (Montrer ARHGEF16 Anticorps) (NB) cells to TAE684 and its derivatives.

  3. Studied axl kinase as a negative regulator of an alveolar epithelial cell phenotype; results found that inhibition of Axl kinase could form epithelial adhesion structure and augment surfactant protein production via the MET of human lung multi-potent cells.

  4. AXL is efficiently and sequentially cleaved by alpha- and gamma-secretases in various types of cancer cell lines. The AXL intracellular domain cleavage product translocates into the nucleus via a nuclear localization sequence that harbored a basic HRRKK motif.

  5. a relationship between AXL and the cellular response to DNA damage whereby abrogation of AXL signaling leads to accumulation of the DNA-damage markers gammaH2AX (Montrer H2AFX Anticorps), 53BP1 (Montrer TP53BP1 Anticorps), and RAD51 (Montrer RAD51 Anticorps).

  6. Small molecule and antibody inhibitors of AXL and MER (Montrer MERTK Anticorps) have recently been described, and some of these have already entered clinical trials. The optimal design of treatment strategies to maximize the clinical benefit of these AXL and MER (Montrer MERTK Anticorps) targeting agents are discussed in relation to the different cancer types and the types of resistance encountered.

  7. our results demonstrate that AR can promote melanoma metastasis via altering the miRNA-539-3p/USP13 (Montrer USP13 Anticorps)/MITF (Montrer MITF Anticorps)/AXL signal and targeting this newly identified signal with AR degradation enhancer ASC (Montrer PYCARD Anticorps)-J9 may help us to better suppress the melanoma metastasis.

  8. AXL can be an effective therapeutic target in combination with targeted therapy such as PARP (Montrer COL11A2 Anticorps) inhibitors in several different malignancies.

  9. AXL/TAZ (Montrer TAZ Anticorps)/YAP (Montrer YAP1 Anticorps) expression is associated with poor prognosis in male breast cancer patients.

  10. High AXL expression is associated with Paclitaxel resistance in breast Cancers.

Mouse (Murine) AXL Receptor tyrosine Kinase (AXL) interaction partners

  1. Both Axl+/- and Axl-/- suckling mice supported the replication of Zika virus.

  2. reciprocal activation of Axl and Mer (Montrer ERH Anticorps) receptor tyrosine kinases has a major impact on the outcome of renal inflammation.

  3. Axl is critical for survival of T lymphocytes, especially during vascular remodeling in hypertension.

  4. Axl, Mertk (Montrer MERTK Anticorps) and Tyro3 (Montrer TYRO3 Anticorps) receptors are not required for Zika virus entry and infection.

  5. Axl plays an essential role in the regulation of NK cell development as well as natural killer effector function.

  6. Matrix metalloproteases ADAM10 (Montrer ADAM10 Anticorps) and TACE (ADAM17 (Montrer ADAM17 Anticorps)) cleave AXL receptor tyrosine kinase (Axl) in lupus-prone leukocytes.

  7. Gas6 (Montrer GAS6 Anticorps)/Axl and Akt (Montrer AKT1 Anticorps)/FoxO1a (Montrer FOXO1 Anticorps) were involved in protective effects of testosterone on VSMCs senescence and collagen synthesis.

  8. Axl allows specific identification of airway macrophages, and that its expression is critical for macrophage functional compartmentalization in the airspaces or lung interstitium.

  9. results establish TAM (Montrer CCNA1 Anticorps) receptors as both controllers of microglial physiology and potential targets for therapeutic intervention in central nervous system disease

  10. These results suggest that TAM (Montrer CCNA1 Anticorps) receptors support NSCs survival, proliferation and differentiation by regulating expression of neurotrophins, especially the nerve growth factor.

Cow (Bovine) AXL Receptor tyrosine Kinase (AXL) interaction partners

  1. activation of receptor tyrosine kinase (Montrer RET Anticorps) Axl inhibits the osteogenic differentiation of vascular pericytes.

AXL profil antigène

Antigen Summary

The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with AXL

  • AXL receptor tyrosine kinase (AXL) anticorps
  • AXL receptor tyrosine kinase (Axl) anticorps
  • Axl receptor tyrosine kinase (Axl) anticorps
  • AI323647 anticorps
  • Ark anticorps
  • JTK11 anticorps
  • Tyro7 anticorps
  • Ufo anticorps

Protein level used designations for AXL

AXL oncogene , AXL transforming sequence/gene , tyrosine-protein kinase receptor UFO , adhesion-related kinase , ufo oncogene homolog

GENE ID SPECIES
100064907 Equus caballus
558 Homo sapiens
26362 Mus musculus
308444 Rattus norvegicus
484490 Canis lupus familiaris
100144875 Sus scrofa
516598 Bos taurus
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