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Human AXL Kit ELISA pour Sandwich ELISA - ABIN624944
Hsiao, Lin, Hsieh, Chu, Shieh, Hsieh, Lee, Hung: Circulating growth arrest-specific 6 protein is associated with adiposity, systemic inflammation, and insulin resistance among overweight and obese adolescents. dans The Journal of clinical endocrinology and metabolism 2013
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The expression of MerTK (Montrer MERTK Kits ELISA) and AxlTK varied according to the deposition of immunoglobulin and complements on glomeruli. Both MerTK (Montrer MERTK Kits ELISA) and AxlTK expressions were increased on glomeruli and varied according to pathological classifications.
High expression level of AXL is associated with lung adenocarcinoma.
AXL is a strong adverse prognostic factor for esophageal squamous cell carcinoma
Our data demonstrate that AXL is a crucial therapeutic target of carvacrol-induced inhibition of NSCLC cell proliferation and migration.
These results show that TYRO3 (Montrer TYRO3 Kits ELISA), AXL and GAS6 (Montrer GAS6 Kits ELISA) are expressed at higher levels in LMS and expression of its ligands correlates to a worse PFS in LMS patients.
miR (Montrer MLXIP Kits ELISA)-34a reconstitution in DMPM cells significantly inhibited proliferation and tumorigenicity, induced an apoptotic response, and declined invasion ability, mainly through the down-regulation of c-MET and AXL and the interference with the activation of downstream signaling.
kinase AXL drives the mesenchymal gene signature and motility of ovarian tumor cells.
The AXL inhibitor R428 attenuated RTK and ERK (Montrer EPHB2 Kits ELISA) activation and reduced cell motility in Mes (Montrer ME1 Kits ELISA) cells in culture and reduced tumor growth
These results highlight the dual role of Axl during Zika virus infection of glial cells: promoting viral entry and modulating innate immune responses.
The expression of AXL was positively associated with GAS6 expression (P < 0.001), and tumor differentiation (P = 0.014) in advanced NSCLC with metastases. AXL expression displayed no association with gender, age, smoking history, pathology, T stage, N stage, CEA, and LDH.
These results demonstrate that AXL is essential for limiting the immunosuppressive effects of type I interferons and enabling the induction of protective antiviral adaptive immunity.
GAS6 (Montrer GAS6 Kits ELISA)-AXL signaling-mediated autophagy induction in murine macrophages ameliorates hepatic inflammatory responses by inhibiting NLRP3 (Montrer NLRP3 Kits ELISA) inflammasome activation.
Both Axl+/- and Axl-/- suckling mice supported the replication of Zika virus.
reciprocal activation of Axl and Mer (Montrer ERH Kits ELISA) receptor tyrosine kinases has a major impact on the outcome of renal inflammation.
Axl is critical for survival of T lymphocytes, especially during vascular remodeling in hypertension.
Axl, Mertk (Montrer MERTK Kits ELISA) and Tyro3 (Montrer TYRO3 Kits ELISA) receptors are not required for Zika virus entry and infection.
Axl plays an essential role in the regulation of NK cell development as well as natural killer effector function.
Matrix metalloproteases ADAM10 (Montrer ADAM10 Kits ELISA) and TACE (ADAM17 (Montrer ADAM17 Kits ELISA)) cleave AXL receptor tyrosine kinase (Axl) in lupus-prone leukocytes.
Gas6 (Montrer GAS6 Kits ELISA)/Axl and Akt (Montrer AKT1 Kits ELISA)/FoxO1a (Montrer FOXO1 Kits ELISA) were involved in protective effects of testosterone on VSMCs senescence and collagen synthesis.
Axl allows specific identification of airway macrophages, and that its expression is critical for macrophage functional compartmentalization in the airspaces or lung interstitium.
activation of receptor tyrosine kinase (Montrer RET Kits ELISA) Axl inhibits the osteogenic differentiation of vascular pericytes.
The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
, AXL transforming sequence/gene
, tyrosine-protein kinase receptor UFO
, adhesion-related kinase
, ufo oncogene homolog