anti-Souris EPH Receptor B4 anticorps pour Immunohistochemistry (Paraffin-embedded Sections)

Recommended EPH Receptor B4 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
EPH Receptor B4 (EPHB4) Anticorps
  • htk
  • myk1
  • ephB4a
  • tyro11
  • ephb4b
  • MGC130997
  • AI042935
  • Htk
  • MDK2
  • Myk1
  • Tyro11
  • HTK
  • MYK1
  • TYRO11
  • EPH receptor B4
  • Eph receptor B4
  • EPHB4
  • ephb4-a
  • ephb4
  • LOC100359286
  • Ephb4
Reactivité
Humain, Souris
160
67
10
1
1
1
1
Hôte
Lapin
70
66
48
20
2
Clonalité
Polyclonal
Conjugué
Cet anticorp EPH Receptor B4 est non-conjugé
8
6
6
5
5
4
4
4
4
3
3
3
3
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
140
106
47
28
21
18
6
5
4
4
3
2
2
1
1
Fournisseur
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N° du produit ABIN498286
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN1537708 IHC (p) WB Rabbit Ig AA 88-118, Center Connectez-vous pour afficher Polyclonal
1 ABIN2001181 IHC (p) ELISA Rabbit IgG AA 1-539 Connectez-vous pour afficher Polyclonal

General

Antigène EPH Receptor B4 (EPHB4) Anticorps
Reactivité Humain, Souris
(160), (67), (10), (1), (1), (1), (1)
Hôte Lapin
(70), (66), (48), (20), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp EPH Receptor B4 est non-conjugé
(8), (6), (6), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(140), (106), (47), (28), (21), (18), (6), (5), (4), (4), (3), (2), (2), (1), (1)
Fournisseur Connectez-vous pour afficher

Détail du produit anti-EPH Receptor B4 anticorps

Détail du antigène EPH Receptor B4 Information d'application Stockage Images
Specificité This antibody detects endogenous levels of EphB4 protein. (region surrounding Glu601)
Réactivité croisée (Details) Species reactivity (tested):Human and Mouse.
Purification Affinity Chromatography using epitope-specific immunogen

Détail du antigène EPH Receptor B4

Détail du produit anti-EPH Receptor B4 anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation EPHB4 (EPHB4 Antibody Extrait)
Sujet EphB4, also known as Htk, Myk1, Tyro11, and Mdk2, is a member of the Eph receptor family, which binds of the ephrin ligand family. Two classes of receptors exist, designated A and B, that have an extracellular domain made up of a globular domain, a cysteine-rich domain, and two fibronectin type III domains, followed by the transmembrane region and cytoplasmic region. The cytoplasmic region contains juxtamembrane motif with two tyrosines, which are the major autophosphorylation sites, along with a kinase domain, and a conserved sterile alpha motif (SAM) in the carboxyl terminus, which includes one conserved tyrosine. Ligand recognition and binding leads to activation of intrinsic kinase activity. Only membrane-bound or Fc-clustered ligands have been shown to activate the receptor in vitro. Soluble monomeric ligands can bind the receptor, but do not induce receptor autophosphorylation and activation. The Eph receptors and ephrin ligands display reciprocal expression in vivo. Developing and adult neural tissue express nearly all of the Eph receptors and ephrin ligands.Ephs and ephrins play a significant role in angiogenesis.Synonyms: Ephrin type-B receptor 4, HTK, TYRO11, Tyrosine-protein kinase TYRO11, Tyrosine-protein kinase receptor HTK
Poids moléculaire approx. 108.0 kDa
ID gène 2050
NCBI Accession NP_004435
UniProt P54760
Pathways Signalisation RTK

Information d'application

Détail du produit anti-EPH Receptor B4 anticorps Détail du antigène EPH Receptor B4 Stockage Images Haut de la page
Indications d'application Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-EPH Receptor B4 anticorps Détail du antigène EPH Receptor B4 Information d'application Images Haut de la page
Concentration 1.0 mg/mL
Buffer PBS, pH ~7.2, 0.05 % Sodium Azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Détail du produit anti-EPH Receptor B4 anticorps Détail du antigène EPH Receptor B4 Information d'application Stockage Haut de la page
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-EPH Receptor B4 (EPHB4) antibody (ABIN498286) Immunohistochemistry analysis of EphB4 Antibody in paraffin-embedded human bra...
Western Blotting (WB) image for anti-EPH Receptor B4 (EPHB4) antibody (ABIN498286) Western blot analysis of EphB4 Antibody in extracts from Jurkat cells.