anti-Souris Ephrin B2 anticorps pour Immunofluorescence

Recommended Ephrin B2 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Ephrin B2 (EFNB2) Anticorps
  • EFNB2
  • efnb2
  • ephrin-B2
  • htkl
  • eplg5
  • htk-l
  • lerk5
  • ephrinB2
  • efnb2a
  • MGC68890
  • efnb2b
  • ELF-2
  • Epl5
  • Eplg5
  • Htk-L
  • LERK-5
  • Lerk5
  • NLERK-1
  • EPLG5
  • HTKL
  • LERK5
  • ephrin-B2
  • ephrin-B2 precursor
  • ephrin B2
  • EFNB2
  • efnb2
  • efnb2-a
  • LOC100357479
  • Efnb2
Épitope
AA 328-332
15
11
10
10
10
5
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
104
49
30
5
5
5
3
3
3
2
2
1
1
Hôte
Lapin
90
18
2
Clonalité
Polyclonal
Conjugué
Cet anticorp Ephrin B2 est non-conjugé
3
3
3
3
3
3
Application
Immunofluorescence (IF), Western Blotting (WB)
91
39
35
25
10
8
3
2
2
2
1
Fournisseur
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N° du produit ABIN197418
$ 368.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN362834 IF WB Rabbit IgG AA 328-332 Connectez-vous pour afficher Polyclonal 4
1 ABIN2881211 IF IHC WB Rabbit IgG Connectez-vous pour afficher Polyclonal
1 ABIN274040 IF WB Rabbit IgG Connectez-vous pour afficher Polyclonal
1 ABIN274041 IF WB Rabbit IgG Connectez-vous pour afficher Polyclonal

General

Antigène Ephrin B2 (EFNB2) Anticorps
Épitope AA 328-332
(15), (11), (10), (10), (10), (5), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(104), (49), (30), (5), (5), (5), (3), (3), (3), (2), (2), (1), (1)
Hôte Lapin
(90), (18), (2)
Clonalité
Polyclonal
Conjugué Cet anticorp Ephrin B2 est non-conjugé
(3), (3), (3), (3), (3), (3)
Application Immunofluorescence (IF), Western Blotting (WB)
(91), (39), (35), (25), (10), (8), (3), (2), (2), (2), (1)
Pubmed 3 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-Ephrin B2 anticorps

Détail du antigène Ephrin B2 Information d'application Stockage References for anti-Ephrin B2 antibody (ABIN197418) Images
Specificité This antibody AP02708PU detects endogenous levels of total Ephrin-B2 protein.
Purification Immunoaffinity Chromatography using epitope-specific immunogen.
Immunogène Peptide Sequence around amino acids 328~332 (N-I-Y-Y-K) derived from Human Ephrin-B2.

Détail du antigène Ephrin B2

Détail du produit anti-Ephrin B2 anticorps Information d'application Stockage References for anti-Ephrin B2 antibody (ABIN197418) Images Haut de la page
Antigène
Autre désignation Ephrin-B2 (EFNB2 Antibody Extrait)
Sujet Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP)and also interacts with PRKCABP and GRIP1. This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. Ephrin-B2 also binds EphA4, EphB1, EphB2, EphB3 and EphB4. Ephrin-B2 can be detected on monocytes, mesangial cells, CD34+ stem cells, bone marrow fibroblasts, activated melanocytes and melanoma cells, and pre-artery endothelial cells.Synonyms: EFNB2, EPH-related receptor tyrosine kinase ligand 5, EPLG5, HTK ligand, HTK-L, HTKL, LERK-5, LERK5
ID gène 1948
NCBI Accession NP_004084
UniProt P52799
Pathways Signalisation RTK, Regulation of Muscle Cell Differentiation

Information d'application

Détail du produit anti-Ephrin B2 anticorps Détail du antigène Ephrin B2 Stockage References for anti-Ephrin B2 antibody (ABIN197418) Images Haut de la page
Indications d'application Western blot: 1/500-1/1000. Immunofluorescence: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-Ephrin B2 anticorps Détail du antigène Ephrin B2 Information d'application References for anti-Ephrin B2 antibody (ABIN197418) Images Haut de la page
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock -20 °C
Stockage commentaire Store the antibody (in aliquots) at -20 °C.

References for anti-Ephrin B2 antibody (ABIN197418)

Détail du produit anti-Ephrin B2 anticorps Détail du antigène Ephrin B2 Information d'application Stockage Images Haut de la page
Background publications

Chrencik, Brooun, Kraus, Recht, Kolatkar, Han, Seifert, Widmer, Auer, Kuhn: "Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity." dans: The Journal of biological chemistry, Vol. 281, Issue 38, pp. 28185-92, 2006

Kertesz, Krasnoperov, Reddy, Leshanski, Kumar, Zozulya, Gill: "The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth." dans: Blood, Vol. 107, Issue 6, pp. 2330-8, 2006

Noren, Lu, Freeman, Koolpe, Pasquale: "Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 15, pp. 5583-8, 2004

Images

Détail du produit anti-Ephrin B2 anticorps Détail du antigène Ephrin B2 Information d'application Stockage References for anti-Ephrin B2 antibody (ABIN197418) Haut de la page
Supplier Images
 image for anti-Ephrin B2 (EFNB2) (AA 328-332) antibody (ABIN197418) anti-Ephrin B2 (EFNB2) (AA 328-332) antibody
 image for anti-Ephrin B2 (EFNB2) (AA 328-332) antibody (ABIN197418) anti-Ephrin B2 (EFNB2) (AA 328-332) antibody (Image 2)