Aperçu des produits pour anti-FLT1 (FLT1) Anticorps

Full name:
anti-Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) Anticorps (FLT1)
Chez www.anticorps-enligne.fr sont 504 Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) Anticorps de 37 de différents fournisseurs disponibles. De plus, nous expédions FLT1 Protéines (74) et FLT1 Kits (67) et beaucoup plus de produits pour cette protéine. Un total de 666 FLT1 produits sont actuellement listés.
Synonymes:
AI323757, FLT, FLT-1, FLT1, flt1b, sFlt1, VEGFR-1, VEGFR1

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anti-FLT1 Anticorps mieux référencés

  1. Human Monoclonal FLT1 Primary Antibody pour FACS - ABIN4897100 : Karrar, Broomé, Uzunel, Qureshi, Sumitran-Holgersson: Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction. dans Gut 2007 (PubMed)
    Show all 16 references for 4897100

  2. Human Monoclonal FLT1 Primary Antibody pour FACS - ABIN4897099 : de Groot, Piao, Tran, Gilbert, Wu, Liu, Bekele, Cloughesy, Mehta, Robins, Lassman, DeAngelis, Camphausen, Chen, Yung, Prados, Wen, Heymach: Myeloid biomarkers associated with glioblastoma response to anti-VEGF therapy with aflibercept. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2011 (PubMed)
    Show all 5 references for 4897099

  3. Human Polyclonal FLT1 Primary Antibody pour IF (p), IHC (p) - ABIN725795 : Cheng, Xiang, Yang, Ma, Zhao: Direct Effects of Bevacizumab on Rat Conjunctival Fibroblast. dans Cell biochemistry and biophysics 2015 (PubMed)
    Show all 3 references for 725795

  4. Human Polyclonal FLT1 Primary Antibody pour IHC (p), WB - ABIN115391 : Ahmed, Li, Dunk, Whittle, Rushton, Rollason: Colocalisation of vascular endothelial growth factor and its Flt-1 receptor in human placenta. dans Growth factors (Chur, Switzerland) 1996 (PubMed)
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  5. Mouse (Murine) Monoclonal FLT1 Primary Antibody pour FACS - ABIN4897105 : Fang, Wei, Pentinmikko, Leinonen, Salven: Generation of functional blood vessels from a single c-kit+ adult vascular endothelial stem cell. dans PLoS biology 2012 (PubMed)
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  6. Mouse (Murine) Monoclonal FLT1 Primary Antibody pour FACS - ABIN4897107 : Reddy, Zhou, Schadler, Jia, Kleinerman: Bone marrow subsets differentiate into endothelial cells and pericytes contributing to Ewing's tumor vessels. dans Molecular cancer research : MCR 2008 (PubMed)
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  7. Human Polyclonal FLT1 Primary Antibody pour IHC, ELISA - ABIN1533118 : Shibuya, Yamaguchi, Yamane, Ikeda, Tojo, Matsushime, Sato: Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family. dans Oncogene 1990 (PubMed)

  8. Human Polyclonal FLT1 Primary Antibody pour EIA, FACS - ABIN955511 : Wong, Buckman, Clemons, Verma, Dent, Trudeau, Roche, Ebos, Kerbel, Deboer, Sutherland, Emmenegger, Slingerland, Gardner, Pritchard: Phase I/II trial of metronomic chemotherapy with daily dalteparin and cyclophosphamide, twice-weekly methotrexate, and daily prednisone as therapy for metastatic breast cancer using vascular endothelial growth factor and soluble vascular endothelial growt dans Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010 (PubMed)

Plus d’anticorps contre FLT1 partenaires d’interaction

Mouse (Murine) Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. Flt1 has a role in blood vessel anastomosis during angiogenesis

  2. First-in-class selective PET tracers for imaging VEGFR-1 and VEGFR-2 (Montrer KDR Anticorps) were constructed and successfully validated in an orthotopic murine tumor model.

  3. these results suggest that VEGFR1 signaling plays a role in regulating the balance between macrophage phenotypes in streptozotocin -induced diabetic wounds, prevents impaired diabetic wound healing, and promotes angiogenesis/lymphangiogenesis.

  4. These data therefore support a tightly controlled, paracrine signaling mechanism of VEGF-B (Montrer VEGFB Anticorps) to VEGFR1.

  5. Flt1/VEGF-A (Montrer VEGFA Anticorps) signalling has stage-specific effects on vascular morphogenesis.

  6. IL-35 treatment reduced collagen-induced arthritis via inhibiting vascular endothelial growth factor and its receptors

  7. the VEGFR-1 tyrosine kinase (Montrer TYRO3 Anticorps) signaling has an effect on angiogenesis.

  8. data suggest that sFlt-1 may have a therapeutic effect on AS, resulting from suppression of VEGF signaling-mediated recruitment of circulating monocytes/macrophages

  9. that Flt-1 plays a critical role in cardiac hypertrophy induced by pressure overload via the activation of AKT (Montrer AKT1 Anticorps)

  10. Flt-1 appears to play a role in oxidative stress, which promotes apoptosis of trophoblasts

Human Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. variants near FLT1 may modulate preeclampsia susceptibility

  2. Flt1 has a role in blood vessel anastomosis during angiogenesis

  3. variants rs35832528 (E982A; P=2.49E-4; odds ratio=0.387) and rs141440705 (R54S; P=0.003; odds ratio=0.442) in Fms related tyrosine kinase 1 significantly associated with maternal protective genetic variants in Preeclampsia in the Finnish Population.

  4. Serum and urinary sFlt-1 and sFlt-1/PLGF (Montrer PGF Anticorps) ratios in severe preeclampsia patients were significantly higher than those in the mild preeclampsia group, and measurements from mild preeclampsia patients were significantly higher than controls

  5. FLT-1 rs7324510 C/A variant may be a new genetic risk factor for severity of rheumatoid arthritis. Examined factor highly predispose to more severe disease activity as well as higher sFLT-1 levels in rheumatoid arthritis.

  6. Molecular dynamics simulations of VEGFR-1 Wt and (p.Cys1110Ser) variant revealed exposure of the activation domain increasing the probability of phosphorylation events: a condition frequently reported in cancers.

  7. The normalized methylation values for the VEGFR1, VEGFR2 (Montrer KDR Anticorps) and VEGFR3 (Montrer FLT4 Anticorps) promoters tended to be higher in the tumour cell lines than in normal tonsil samples, whereas amounts of VEGFR1, VEGFR2 (Montrer KDR Anticorps) and VEGFR3 (Montrer FLT4 Anticorps) messenger RNA were significantly higher

  8. Both the TNF-alpha (Montrer TNF Anticorps)/IL-10 (Montrer IL10 Anticorps) and sFlt-1/PlGF (Montrer PGF Anticorps) ratios were higher in placental homogenate of early-onset Preeclampsia (PE) than late-onset PE and control groups. The more severe lesions and the imbalance between TNF-alpha (Montrer TNF Anticorps)/IL-10 (Montrer IL10 Anticorps) and PlGF (Montrer PGF Anticorps)/sFlt-1 in placentas from early-onset PE allows differentiation of early and late-onset PE and suggests higher placental impairment in early-onset PE

  9. this study shows that Fli-1 (Montrer FLI1 Anticorps) plays a major role in the regulation of granulocyte colony stimulating factor (Montrer CSF3 Anticorps)

  10. Patients with post-peripartum cardiomyopathy have significantly higher plasma sFlt1 concentration with a trend of somewhat higher levels of VEGF (Montrer VEGFA Anticorps) and significantly decreased VEGF (Montrer VEGFA Anticorps)/sFlt1 ratio compared to controls.

Cow (Bovine) Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. There is a possibility that steatosis can be suppressed by the CC genotype in VEGFR1.

  2. These results suggest that non-dominant follicles maintain a greater concentration of the mRNA expression of both membrane and soluble VEGF receptors; but follicular dominance is related to a reduction in the mRNA expression of sVEGFR1 and sVEGFR2.

  3. VEGFR-1 negatively regulates primary bovine retinal pericytes survival, and its blockade protects the blood-brain barrier integrity.

  4. gamma-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1

  5. VEGFR1 mRNA expression was lower at estrus and at the early I and early II luteal stages than at the other stages, whereas VEGFR1 protein expression did not change significantly throughout the estrous cycle (P<0.05)

  6. Alterations in the expression of VEGF-A (Montrer VEGFA Anticorps) and bFGF (Montrer FGF2 Anticorps) systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.

  7. inhibition of VEGFR-1 results in decrease in number of capillary connections indicating VEGFR-1 ligands promote branching angiogenesis.

  8. TGF-beta1 (Montrer TGFB1 Anticorps) induction of VEGFR-1 in endothelial cells explains pericyte protection of vessels and the selective vulnerability of neonatal vessels to oxygen(VEGFR-1)

  9. the activation of VEGFR-1 and VEGFR-2 (Montrer KDR Anticorps) heterodimer (VEGFR-1/R-2) is essential for PGI(2 (Montrer PTGIR Anticorps)) synthesis mediated by VEGF-A (Montrer VEGFA Anticorps)(165) and VEGF-A (Montrer VEGFA Anticorps)(121), which cannot be reproduced by the parallel activation of VEGFR-1 and VEGFR-2 (Montrer KDR Anticorps) homodimers with corresponding agonists

  10. PEDF (Montrer SERPINF1 Anticorps) and VEGFR-1 have roles in the negative regulation of angiogenesis

Pig (Porcine) Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. we analyzed the expression and cellular distribution of Flt-1(VEGFR-1) and Flk-1 (KDR/VEGFR-2 (Montrer KDR Anticorps))in newborn piglet brain

  2. data shows that members of the VEGF (Montrer VEGFA Anticorps)-VEGFR (Montrer KDR Anticorps) system are temporally and spatially well localized for playing key roles during umbilical cord formation and its intensive growth observed after day 75 of pregnancy

  3. The VEGFR1 was stably expressed during the whole lifespan of mesonephric glomeruli, and VEGFR1 is important for the maintenance of endothelial fenestrations.

  4. increased placental expression of the VEGF receptor system is associated with increased placental vascular density observed with the advancement of gestation in the pig.

  5. EGFR (Montrer EGFR Anticorps), VEGFR (Montrer KDR Anticorps) and FGFR (Montrer FGFR2 Anticorps) are expressed in porcine oviduct and endometrium during the time of implantation [review]

  6. VEGF ligand-receptor system may play an important role in the development and maintenance of the corpus luteum in pigs.

  7. VEGF (Montrer VEGFA Anticorps)/Flk-1 (Montrer KDR Anticorps)/Flt-1 system is activated during myocardial ischemia reperfusion injury.

  8. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (Montrer VEGFA Anticorps), pro-MMP-9 (Montrer MMP9 Anticorps), MMP-2 (Montrer MMP2 Anticorps), VEGFR-1, VEGFR-2 (Montrer KDR Anticorps), and TIMP-1 (Montrer TIMP1 Anticorps), which may contribute to the development of venous stenosis.

  9. in experimental intervertebral disc degeneration, VEGF receptors were expressed in the damaged disc and paradiscal tissues

Zebrafish Fms-Related tyrosine Kinase 1 (Vascular Endothelial Growth Factor/vascular Permeability Factor Receptor) (FLT1) interaction partners

  1. Flt1-tyrosine kinase (TK) activity contributed significantly in endothelial cells survival and vascular development during embryo angiogenesis in zebrafish by engaging PI3K/Akt (Montrer AKT1 Anticorps) pathway.

  2. Elevated Notch (Montrer NOTCH1 Anticorps) signaling downstream of perturbed VEGF (Montrer VEGFA Anticorps) signaling contributes to aberrant flt-1(-/-) blood vessel formation.

  3. Data indicate that the increase in FLT1/sFLT1 protein levels upon miR-10 (Montrer LILRB2 Anticorps) knockdown inhibited the angiogenic behavior of endothelial cells largely by antagonizing vascular endothelial growth factor receptor 2 (Montrer KDR Anticorps) signaling.

FLT1 profil antigène

Antigen Summary

This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.

Alternative names and synonyms associated with FLT1

  • fms-related tyrosine kinase 1 (FLT1) anticorps
  • vascular endothelial growth factor receptor 1 (CpipJ_CPIJ012087) anticorps
  • FMS-like tyrosine kinase 1 (Flt1) anticorps
  • FMS-related tyrosine kinase 1 (Flt1) anticorps
  • fms-related tyrosine kinase 1 (Flt1) anticorps
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (FLT1) anticorps
  • fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) (flt1) anticorps
  • vascular endothelial growth factor receptor-1 (FLT-1) anticorps
  • AI323757 anticorps
  • FLT anticorps
  • FLT-1 anticorps
  • FLT1 anticorps
  • flt1b anticorps
  • sFlt1 anticorps
  • VEGFR-1 anticorps
  • VEGFR1 anticorps

Protein level used designations for FLT1

fms-related tyrosine kinase 1 , vascular endothelial growth factor receptor 1 , embryonic receptor kinase 2 , tyrosine-protein kinase receptor FLT , vascular endothelial growth factor receptor-1 , vascular permeability factor receptor , fms-like tyrosine kinase 1 , fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) , tyrosine-protein kinase FRT , FLT-1 , FMS-like tyrosine kinase 1 , Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) , VEGF-receptor , flt-receptor , vascular endothelial growth factor 1 , vascular endothelial growth factor/vascular permeability factor receptor , ascular endothelial growth factor/vascular permeability factor receptor , VEGFR-1 , flt-1 type VEGF receptor , receptor tyrosine kinase Flt1b , soluble fms-like tyrosine kinase 1

GENE ID SPECIES
443088 Ovis aries
6044537 Culex quinquefasciatus
14254 Mus musculus
2321 Homo sapiens
54251 Rattus norvegicus
100732326 Cavia porcellus
503620 Bos taurus
403727 Canis lupus familiaris
374100 Gallus gallus
396763 Sus scrofa
544667 Danio rerio
443182 Ovis aries
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