Aperçu des produits pour anti-NFAT1 (NFAT1) Anticorps

Full name:
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Anticorps (NFAT1)
Chez www.anticorps-enligne.fr sont 153 Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) Anticorps de 21 de différents fournisseurs disponibles. De plus, nous expédions NFAT1 Protéines (7) et NFAT1 Kits (6) et beaucoup plus de produits pour cette protéine. Un total de 172 NFAT1 produits sont actuellement listés.
Synonymes:
AI607462, NF-ATc2, NFAT1, NFAT1-D, NFATC2, NFATP
afficher tous les anticorps Gène GeneID UniProt
NFAT1 18019 Q60591
NFAT1 4773 Q13469
NFAT1 311658  

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anti-NFAT1 Anticorps mieux référencés

  1. Human Monoclonal NFAT1 Primary Antibody pour ChIP, ELISA - ABIN152663 : Bonnet, Rochefort, Sutendra, Archer, Haromy, Webster, Hashimoto, Bonnet, Michelakis: The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. dans Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
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  2. Dog (Canine) Monoclonal NFAT1 Primary Antibody pour IF, IP - ABIN968123 : Boise, Petryniak, Mao, June, Wang, Lindsten, Bravo, Kovary, Leiden, Thompson: The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB. dans Molecular and cellular biology 1993 (PubMed)
    Show all 5 references for 968123

  3. Cow (Bovine) Polyclonal NFAT1 Primary Antibody pour WB - ABIN2779960 : Glud, Sørensen, Andrulis, Wang, Kondo, Jessen, Krenacs, Stelkovics, Wabl, Serfling, Palmetshofer, Pedersen: A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus. dans Blood 2005 (PubMed)
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  4. Human Polyclonal NFAT1 Primary Antibody pour EIA - ABIN358367 : Golks, Tran, Goetschy, Guerini: Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation. dans The EMBO journal 2007 (PubMed)
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  5. Human Monoclonal NFAT1 Primary Antibody pour IF, IP - ABIN967558 : Crabtree: Contingent genetic regulatory events in T lymphocyte activation. dans Science (New York, N.Y.) 1989 (PubMed)
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  6. Human Polyclonal NFAT1 Primary Antibody pour ELISA, IHC - ABIN4339294 : Celil Aydemir, Lee, Won Kim, Gardner, Prince, Mok Ahn, Lee, Young-In Lee: Nuclear factor of activated T cell mediates proinflammatory gene expression in response to mechanotransduction. dans Annals of the New York Academy of Sciences 2007 (PubMed)

Plus d’anticorps contre NFAT1 partenaires d’interaction

Mouse (Murine) Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) interaction partners

  1. These results support the idea that NFAT1 is necessary to fully suppress effector responses during Plasmodium-induced CD4 (Montrer CD4 Anticorps)(+) T cell exhaustion.

  2. These results demonstrate a repressor role for NFAT1 in cell cycle progression and Cyclin E (Montrer CCNE1 Anticorps) expression in B lymphocytes, and suggest a potential function for NFAT1 protein in B cell malignancies.

  3. Overexpression of either ca-Nfatc2 or ca-Nfatc1 (Montrer NFATC1 Anticorps) in mouse islets enhanced insulin (Montrer INS Anticorps) secretion, whereas only ca-Nfatc2 was able to promote b-cell proliferation, suggesting distinct molecular pathways mediating insulin (Montrer INS Anticorps) secretion vs. b-cell proliferation are regulated by NFAT (Montrer NFATC1 Anticorps)

  4. our results suggest the NFAT1 plays a pivotal role as a genetic switch in CD4 (Montrer CD4 Anticorps)(+)/CD8 (Montrer CD8A Anticorps)(+) T cell tolerance by regulating AICD process in the T cell mediated skin inflammation.

  5. It is a non-Hsp gene, which is essential for HSF1 (Montrer HSF1 Anticorps)-mediated maintenance of whole body homeostasis

  6. NFAT (Montrer NFATC1 Anticorps) directs signaling enzymes to gene promoters in islets.

  7. FOXP3 (Montrer FOXP3 Anticorps) can inhibit NFAT (Montrer NFATC1 Anticorps) driven expression of CD40L (Montrer CD40LG Anticorps) and IL-17 (Montrer IL17A Anticorps) in CD4 (Montrer CD4 Anticorps) T cells through its interaction with NFAT1 and inhibition of this interaction by a short synthetic peptide can modulate effector T cell activity

  8. Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis.

  9. our findings reveal a new signaling pathway in microglia that couples TLR4 (Montrer TLR4 Anticorps) activation with the translocation of NFAT1 into mitochondria to control the microglial activation during brain infection.

  10. In Nfat1(-/-) CD4 (Montrer CD4 Anticorps)(+) T cells, the expression of anti-inflammatory lymphokines was mediated by NFAT2 (Montrer NFATC1 Anticorps), thus directly enabling protective IL expression.

Human Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) interaction partners

  1. An interaction of NFAT1 and the beta-catenin (Montrer CTNNB1 Anticorps) pathway, validate lysophosphatidic acid as an in vivo activator of beta-catenin (Montrer CTNNB1 Anticorps)-dependent transcription during allograft fibrogenesis.

  2. the expression of NFATc2 promotes melanoma dedifferentiation and immune escape

  3. NFAT1 is stimulated by subplasmalemmal Ca2 (Montrer CA2 Anticorps)+ microdomains, whereas NFAT4 (Montrer NFATC3 Anticorps) additionally requires Ca2 (Montrer CA2 Anticorps)+ mobilization from the inner nuclear envelope by nuclear InsP3 receptors.

  4. NFAT1 overexpression is associated with Melanoma Tumor Growth and Metastasis.

  5. These results demonstrate a repressor role for NFAT1 in cell cycle progression and Cyclin E (Montrer CCNE1 Anticorps) expression in B lymphocytes, and suggest a potential function for NFAT1 protein in B cell malignancies.

  6. revealed more than 170 NFAT (Montrer NFATC1 Anticorps)-associated proteins, half of which are involved in transcriptional regulation. Among them are many hitherto unknown interaction partners of NFATc1 (Montrer NFATC1 Anticorps) and NFATc2 in T cells, such as Raptor (Montrer RPTOR Anticorps), CHEK1 (Montrer CHEK1 Anticorps), CREB1 (Montrer CREB1 Anticorps), RUNX1 (Montrer RUNX1 Anticorps), SATB1 (Montrer SATB1 Anticorps), Ikaros (Montrer IKZF1 Anticorps), and Helios (Montrer ZNFN1A2 Anticorps).

  7. NFAT1 silencing could suppress cell migration and invasion through MMP-3 (Montrer MMP3 Anticorps).

  8. FOXP1 (Montrer FOXP1 Anticorps) has protein-protein interaction with NFAT1 on DNA and enhances breast cancer cell migration by repressing NFAT1 transcriptional activity.

  9. we describe a novel mechanism by which GSK-3beta (Montrer GSK3b Anticorps) fine-tunes NFATc2 and STAT3 (Montrer STAT3 Anticorps) transcriptional networks to integrate upstream signaling events that govern pancreatic cancer progression and growth.

  10. Up-regulation of Store-operated Ca2 (Montrer CA2 Anticorps)+ Entry and Nuclear Factor of Activated T Cells Promote the Acinar Phenotype of the Primary Human Salivary Gland Cells.

NFAT1 profil antigène

Antigen Summary

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Alternative names and synonyms associated with NFAT1

  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (NFATC2) anticorps
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (nfatc2) anticorps
  • nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 (Nfatc2) anticorps
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (Nfatc2) anticorps
  • AI607462 anticorps
  • NF-ATc2 anticorps
  • NFAT1 anticorps
  • NFAT1-D anticorps
  • NFATC2 anticorps
  • NFATP anticorps

Protein level used designations for NFAT1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 , nuclear factor of activated T-cells, cytoplasmic 2-like , NF-ATp , NFAT pre-existing subunit , T-cell transcription factor NFAT1 , nuclear factor of activated T-cells, cytoplasmic 2 , NF-ATc2 , NFAT transcription complex, preexisting component , T cell transcription factor NFAT1 , nuclear factor of activated T-cells, preexisting component , preexisting nuclear factor of activated T-cells 2

GENE ID SPECIES
100052657 Equus caballus
469972 Pan troglodytes
100450332 Pongo abelii
100464798 Ailuropoda melanoleuca
100542144 Meleagris gallopavo
100556205 Anolis carolinensis
100599959 Nomascus leucogenys
710601 Macaca mulatta
100414856 Callithrix jacchus
100490186 Xenopus (Silurana) tropicalis
18019 Mus musculus
4773 Homo sapiens
311658 Rattus norvegicus
485930 Canis lupus familiaris
100134969 Sus scrofa
530401 Bos taurus
419346 Gallus gallus
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