Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Sélectionnez vos espèces et l'application
anti-Human TLR4 Anticorps:
anti-Mouse (Murine) TLR4 Anticorps:
anti-Rat (Rattus) TLR4 Anticorps:
Vous arrivez à notre recherche pré-filtrée.
Human Monoclonal TLR4 Primary Antibody pour BP, CyTOF - ABIN4360167
Degraaf, Zasłona, Bourdonnay, Peters-Golden: Prostaglandin E2 reduces Toll-like receptor 4 expression in alveolar macrophages by inhibition of translation. dans American journal of respiratory cell and molecular biology 2014
Show all 24 Pubmed References
Human Monoclonal TLR4 Primary Antibody pour ChIP, CyTOF - ABIN252522
Kessel, Toubi, Pavlotzky, Mogilner, Coran, Lurie, Karry, Sukhotnik et al.: Treatment with glutamine is associated with down-regulation of Toll-like receptor-4 and myeloid differentiation factor 88 expression and decrease in intestinal mucosal injury caused by ... dans Clinical and experimental immunology 2008
Show all 63 Pubmed References
Human Monoclonal TLR4 Primary Antibody pour FACS - ABIN251961
Allam, Peng, Appel, Wenghoefer, Niederhagen, Bieber, Bergé, Novak: Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells. dans The Journal of allergy and clinical immunology 2008
Show all 22 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody pour FACS - ABIN252065
Konno, Wakabayashi, Akashi-Takamura, Ishii, Kobayashi, Takahashi, Kusumoto, Saitoh, Yoshizawa, Miyake: A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression. dans Biochemical and biophysical research communications 2005
Show all 24 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody pour BP, CyTOF - ABIN4360119
Basak, Pathak, Bhattacharyya, Mandal, Pathak, Kundu et al.: NF-kappaB- and C/EBPbeta-driven interleukin-1beta gene expression and PAK1-mediated caspase-1 activation play essential roles in interleukin-1beta release from Helicobacter pylori ... dans The Journal of biological chemistry 2005
Show all 22 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody pour BP, CyTOF - ABIN4360113
Rallabhandi, Bell, Boukhvalova, Medvedev, Lorenz, Arditi, Hemming, Blanco, Segal, Vogel: Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling. dans Journal of immunology (Baltimore, Md. : 1950) 2006
Show all 44 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody pour FACS - ABIN4360117
Mempel, Voelcker, Köllisch, Plank, Rad, Gerhard, Schnopp, Fraunberger, Walli, Ring, Abeck, Ollert et al.: Toll-like receptor expression in human keratinocytes: nuclear factor kappaB controlled gene activation by Staphylococcus aureus is toll-like receptor 2 but not toll-like receptor 4 or platelet ... dans The Journal of investigative dermatology 2003
Show all 23 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody pour FACS, ICC - ABIN4360164
Cognasse, Hamzeh, Chavarin, Acquart, Genin, Garraud: Evidence of Toll-like receptor molecules on human platelets. dans Immunology and cell biology 2005
Show all 21 Pubmed References
Dog (Canine) Monoclonal TLR4 Primary Antibody pour BP, ELISA - ABIN4360158
Scheel, Papavlassopoulos, Blunck, Gebert, Hartung, Zähringer, Seydel, Schromm: Cell activation by ligands of the toll-like receptor and interleukin-1 receptor family depends on the function of the large-conductance potassium channel MaxiK in human macrophages. dans Infection and immunity 2006
Show all 18 Pubmed References
Human Monoclonal TLR4 Primary Antibody pour FACS - ABIN4360193
Zanoni, Navone, Lunardi, Tridente, Bason, Sivori, Beri, Dolcino, Valletta, Corrocher, Puccetti: In celiac disease, a subset of autoantibodies against transglutaminase binds toll-like receptor 4 and induces activation of monocytes. dans PLoS medicine 2006
Show all 16 Pubmed References
TLR4 gene polymorphism plays a role in the common pathophysiology of CP and COPD (Montrer ARCN1 Anticorps), indicating that CP patients with TLR4 gene rs1927907 polymorphism may be more susceptible to COPD (Montrer ARCN1 Anticorps)
In conclusion, we could not detect any direct link between genotypes or allele frequencies of SNP rs4986790 in the TLR4 gene and POAG. In contrast, genotype (A/A) may be protective against POAG especially among individuals with no family history of glaucoma.
TLR4 rs4986790 and rs4986791 gene polymorphism is a risk for UTI (Montrer AMBP Anticorps) development.
This study showed that the induction level of IL-32 (Montrer IL32 Anticorps) was increased in chronic rhinosinusitis with nasal polyps compared to normal nasal mucosa and that LPS (Montrer IRF6 Anticorps)-induced IL-32 (Montrer IL32 Anticorps) expression in nasal polyp-derived fibroblasts was regulated via the TLR4/JNK (Montrer MAPK8 Anticorps)/AKT (Montrer AKT1 Anticorps)/CREB (Montrer CREB1 Anticorps) signaling pathway.
monocytes interact specifically with Chitosan-Fibrinogen (Ch-Fg) via TLR-4, triggering particular intracellular signalling pathways (ERK (Montrer EPHB2 Anticorps) and JNK (Montrer MAPK8 Anticorps), but not p38 (Montrer CRK Anticorps)), downstream of TLR-4. Functionally, Ch-Fg induced monocytes to produce the osteogenic mediator BMP-2 (Montrer BMP2 Anticorps).
TLR4 negatively regulates the proliferation of keratinocytes and its overexpression reduces tumor growth of SCC (Montrer CYP11A1 Anticorps) cells
The results highlight the importance of the inflammatory mediators, IFN-gamma (Montrer IFNG Anticorps) and TLR4, in the pathogenesis of aseptic loosening; increased pro-inflammatory status was associated with early time to revision, whereas IL-4 (Montrer IL4 Anticorps) correlated with longer implant survival
Biglycan stimulation of endothelial cells increased the interaction between NF-kB and the HIF-1alpha promoter, leading to enhanced promoter activity and increased HIF-1alpha mRNA levels, as well as augmented HIF-1 activity that resulted in VEGF expression.
cathelicidin selectively modulated synthesis of TLR4 and 9 in intestinal epithelium, but only when cells were exposed to virulence factors, mostly from apical surfaces.
The emerging role of TLR4 in myocardial inflammation and ways to inhibit its signal transduction in myocardial diseases have been summarized. (Review)
M. scrofulaceum induces a semimature DC phenotype that is characterized by PD-L2 (Montrer PDCD1LG2 Anticorps) over-expression and elevated synthesis of IL-10 (Montrer IL10 Anticorps), most likely through TLR4 and Raf-1 (Montrer RAF1 Anticorps) signaling pathway-dependent DC-SIGN (Montrer CD209 Anticorps) stimulation.
TLR4 deficiency prevented indomethacin-induced small intestinal damage
This study supports a role for TLR2 (Montrer TLR2 Anticorps) and TLR4 in periodontal disease and atherosclerosis, corroborating an intricate association between two inflammatory diseases.
Hemorrhagic shock primes for lung vascular endothelial cell pyroptosis following lipopolysaccharide exposure through TLR4, which activates Nlrp3 (Montrer NLRP3 Anticorps), and subsequently induces caspase-1 (Montrer CASP1 Anticorps) activation.
The results indicate that adipose-derived mesenchymal stem cells (ADSCs) can increase the survival of fat transplants through the modulation of inflammatory and oxidative responses via Nrf2 (Montrer NFE2L2 Anticorps) and TLR4, suggesting potential strategies to improve the use of ADSCs for cell therapy.
Furthermore, it was observed that inflammatory cytokine levels were reduced in TLR2 (Montrer TLR2 Anticorps)-/- mice after Treg transfer. Thus, these data indicate that TLR2 (Montrer TLR2 Anticorps)/TLR4 regulate F. nucleatum-induced inflammatory cytokines through Tregs in vivo.
Evaluation of the adjuvant effect of agonists of toll-like receptor 4 and 7/8 in a vaccine against leishmaniasis
These effects were attenuated in BMDMs isolated from TLR4(-/-) mice.
strains that preferentially activate TLR2 (Montrer TLR2 Anticorps), and others that also activate TLR4
Dichotomous effects of TLR4 on adipose tissue functionality, with an important positive role of TLR4 during a chronic high fat diet challenge due to the lack of adipose tissue remodeling and a negative role of TLR4 as a mediator of insulin (Montrer INS Anticorps) resistance in the adipocyte during an acute challenge with saturated fatty acids.
STA3 (Montrer ARHGEF3 Anticorps) facilitates TLR4-dependent IL-6 (Montrer IL6 Anticorps) and IL-8 (Montrer IL8 Anticorps) production via IL-6 (Montrer IL6 Anticorps) receptor-positive feedback in endometrial cells.
Studied genetic diversity of the Toll-like receptor gene TLR4 in Czech Red and Czech Red Pied cattle. Found 8 SNPs, which were grouped into 18 haplotypes.
TLR4 polymorphisms are associated with lower reproductive Performance.
As a pilot study, the present results revealed that identified SNPs in IL8 (Montrer IL8 Anticorps) and TLR4 genes can be used as a genetic marker and predisposing factor for resistance/susceptibility to digital dermatitis in dairy cows. However, TLR4 gene may be a potential candidate for such disease.
Transcription levels of TLR2 (Montrer TLR2 Anticorps), TLR4, and CD14 (Montrer CD14 Anticorps) in Holstein cows with retained placenta significantly decreased between the first and the seventh day postpartum.
Bovine viral diarrhea virus type 2 infection modulates TLR4 responsiveness in differentiated myeloid cells.
TLR2 (Montrer TLR2 Anticorps) and TLR4 mediate innate response against Cryptosporidium parvum in bovine intestinal epithelial cells.
TLR4 polymorphisms are associated with susceptibility to Mycobacterium avium ssp. paratuberculosis infection in Holsteins
positive correlation between lower neutrophil apoptosis and higher expression of TLR2 (Montrer TLR2 Anticorps) and TLR4 with the formation of NETs and change in surface architecture.
Studied SNPs in the bovine toll-like receptor 4 (TLR4) and monocyte chemo attractant protein-1(CCL2 (Montrer CCL2 Anticorps)) genes.
TLR2 (Montrer TLR2 Anticorps), 3, 4, and 8 mRNA expression is strongly upregulated and correlates with the progression of atherosclerosis in the aorta. Fluvastatin significantly inhibited this progress and reduced inflammation via TLR downregulation.
The expression of TLR4 protein and mRNA, the level of activated NF-kappaB (Montrer NFKB1 Anticorps) (p65 (Montrer SYT1 Anticorps)) were respectively detected.
Lipopolysaccharide upregulates the expression of rabbit TLR2 (Montrer TLR2 Anticorps) and 4 in the uterine body and horn, and the expression of TLR4 in the ovary.
Polydatin might have a protective effect on lung ischemia/reperfusion injury by down-regulating TLR4 and NF-kappaB (Montrer NFKB1 Anticorps) expression, then inhibiting the release of mediators of inflammation as ICAM-1 (Montrer ICAM1 Anticorps).
TLR4 expression is upregulated in the brain after experimental subarachnoid haemorrhage
The elevated expression of TLR4 was detected after SAH (Montrer ACSM3 Anticorps) and peaked on day 3 and 5. TLR4 is increasingly expressed in a parallel time course to the development of cerebral vasospasm in a rabbit experimental model of SAH (Montrer ACSM3 Anticorps).
These results further confirm the involvement of the TLR4 signaling pathway in resistance to E. coli F18 (Montrer MAMLD1 Anticorps) in Meishan weaned piglets.
Data suggest expression of TLR4 and NFKB (nuclear factor kappa B) are regulated by dietary factors affecting innate immunity; here, Lactobacillus acidophilus in feed down-regulates expression of TLR4 and NFKB in mononuclear cells after LPS (Montrer IRF6 Anticorps) challenge.
At 30 days after autotransplantation of a pig kidney, mRNA expression increases for TLR4.
Data suggest TLR2 (Montrer TLR2 Anticorps), TLR4, and calcium signaling in enterocytes play principal roles in mucosal immunity against enterotoxigenic Escherichia coli; probiotic Lactobacillus delbrueckii and its extracellular polysaccharides appear to stimulate TLR2 (Montrer TLR2 Anticorps)/TLR4.
TLR2 (Montrer TLR2 Anticorps) is required for the suppression of TLR4 signaling activation.
The current study screened for single nucleotide polymorphisms (SNPs) in the TLR4 gene and tested their association with Salmonella fecal shedding.
The role of TLR2 (Montrer TLR2 Anticorps), TLR4 and RP105 (Montrer CD180 Anticorps)/MD1 (Montrer LY86 Anticorps) in the immunoregulatory effect of acidic exopolysaccharides from Lactobacillus plantarum N14 (Montrer CLPTM1 Anticorps), is reported.
Data suggest expression of TLR4 in liver can be regulated by dietary factors; here, supplementation with aspartate down-regulates expression of TLR4 in liver in a model of liver disease.
Fish Oil attenuates the activation of the HPA (Montrer HPSE Anticorps) axis induced by LPS (Montrer IRF6 Anticorps) challenge. So it may be associated with decreasing the production of brain or peripheral proinflammatory cytokines through inhibition of TLR4 and NOD signaling pathways in weaned pigs.
Single nucleotide polymorphisms in TLR4 is associated with immune response to gram-negative bacterial infections.
The research findings suggest that Th17 cells are involved in active equine inflammatory bowel disease, and that TLR4 expression was increased in affected horses.
A low steady expression of TLR4, MD-2 (Montrer LY96 Anticorps) and CD14 (Montrer CD14 Anticorps) mRNA was demonstrated for the intestinal samples with no variation between the intestinal segments analysed.
In the present study, the authors show that TLR4 expression is significantly decreased following the exogenous expression of BPV-1 E2 and E7 in primary equine fibroblasts.
evidence that pulmonary intravascular macrophages are equipped with TLR4 to handle and rapidly respond to circulating endotoxins
TLR4/MD-2 (Montrer LY96 Anticorps) complex is responsible for recognition of Rhodococcus spheroides lipopolysaccharide as an agonist in equine cells.
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
, homolog of Drosophila toll
, lipopolysaccharide response
, Toll-like receptor4 protein
, Toll-like receptor 4-like protein