Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher tous les synonymes
This study indicates that CISH functions as a conserved in vivo target and regulator of STAT5 (Montrer STAT5B Kits ELISA) in the control of embryonic hematopoiesis.
the type II SOCS genes (CISH, SOCS1 (Montrer SOCS1 Kits ELISA)-3) are particularly relevant to immune regulation in fish
Studies indicate that suppressors of cytokine signaling (SOCS) proteins CIS, SOCS1 (Montrer SOCS1 Kits ELISA), and SOCS3 (Montrer SOCS3 Kits ELISA) can be considered the third immunocheckpoint molecules since they regulate cytokine signals that control the polarization of CD4 (Montrer CD4 Kits ELISA)(+) T cells and the maturation of CD8 (Montrer CD8A Kits ELISA)(+) T cells.
CISH rs414171 and rs6768300 variants might be associated with protection from pulmonary tuberculosis in Zahedan, Southeast Iran.
This study showed that there was significantly increased levels of CIS mRNA in elderly and Alzheimer's disease brains.
Data indicate that CIS protein stability is regulated through multiple mechanisms, including ubiquitination and interaction with Elongin B (Montrer TCEB2 Kits ELISA)/C proteins, whereas CIS functional inhibition of PRLR (Montrer PRLR Kits ELISA) signaling is dependent on the Elongin B (Montrer TCEB2 Kits ELISA)/C interaction.
SOCS single nucleotide polymorphism is associated with breast cancer.
Study in Chinese Han population confirms that previously identified variants of CISH are associated with susceptibility to pulmonary tuberculosis.
CISH gene polymorphisms at -292 (rs414171) are associated with HBV clearance in HBeAg-positive CHB patients in the immune active phase, and AA is a favorable genotype for this effect.
Two SNPs (rs414171 and rs2239751) in the CISH gene were associated with persistent HBV infection in Han Chinese population
two genetic variants in CISH gene appear to increase susceptibility to TB in Chinese Han population
CISH promoter rs414171 and rs809451 polymorphisms may play a vital role in mediating individual susceptibility to tuberculosis
this study identifies CIS as a critical negative regulator of IL-15 (Montrer IL15 Kits ELISA) signaling in NK cells
Data show that cytokine inducible SH2-containing protein Cish is induced upon T cell receptor stimulation and in the tumor microenvironment.
Results show that CISH has no non-redundant functions in beta cell proliferation or glucose homeostasis during pregnancy in mice. Socs2 (Montrer SOCS2 Kits ELISA) might compensate for the loss of Cish during pregnancy.
CIS has a critical role in controlling the proallergic generation of helper T cells.
CISH expression at the later stage of dendritic cell development triggers the shutdown of DC progenitor cell proliferation and facilitates DC differentiation into a potent stimulator of CTLs.
CIS and SOCS3 (Montrer SOCS3 Kits ELISA) play a role as negative feedback inhibitors of PRL (Montrer PRL Kits ELISA) action; Inhibition of CIS and SOCS3 (Montrer SOCS3 Kits ELISA) expression by glucocorticoids contributes to the positive effect of glucocorticoids on PRL (Montrer PRL Kits ELISA)-induced STAT5 (Montrer STAT5A Kits ELISA) activation.
Induction of CIS in response to EPO (Montrer EPO Kits ELISA) stimulation depends on Stat5 (Montrer STAT5A Kits ELISA) but not MAP kinase (Montrer MAPK1 Kits ELISA) or PI 3 (Montrer PI3 Kits ELISA)-kinase. Overexpression negatively regulates EPO (Montrer EPO Kits ELISA)-mediated cell proliferation, Stat5 (Montrer STAT5A Kits ELISA) phosphorylation, & activation of a Stat (Montrer STAT1 Kits ELISA)-dependent luciferase reporter.
CIS negatively regulates signaling at two levels, apoptosis and proliferation, and thereby sets a threshold for signal transduction
IL-6 (Montrer IL6 Kits ELISA) inhibits hepatic GH signaling by upregulating Cis and Socs-3 (Montrer SOCS3 Kits ELISA), which may involve activation of STAT3 (Montrer STAT3 Kits ELISA).
histone acetylation and chromatin remodeling events occurring during transcriptional activation of the endogenous murine Cis gene, a STAT5 (Montrer STAT5A Kits ELISA) target gene
The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
cytokine inducible SH2-containing protein
, cytokine-inducible SH2-containing protein
, cytokine inducible SH2 containing protein
, cytokine inducible SH2-containing protein A
, twinfilin, actin-binding protein, homolog 1, like
, Cytokine-inducible SH2-containing protein
, cytokine-inducible inhibitor of signaling type 1B
, suppressor of cytokine signaling
, cytokine-inducible SH2 protein
, cytokine inducible SH2-containing protein 1