anti-Humain EPO anticorps pour Functional Studies

Recommended EPO Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Erythropoietin (EPO) Anticorps
  • EPO
  • EP
  • MVCD2
  • erythropoietin
  • EPO
  • epo
  • Epo
Reactivité
Humain
339
76
43
7
4
3
3
2
2
1
1
1
1
1
1
Hôte
Lapin
192
171
15
5
3
1
Clonalité
Polyclonal
Conjugué
Cet anticorp EPO est non-conjugé
28
21
16
10
6
6
6
5
5
5
5
5
5
5
5
4
4
4
4
3
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
249
216
66
60
57
51
30
13
10
10
7
5
4
3
2
2
2
2
2
1
1
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N° du produit ABIN112633
473,00 €
Plus frais de livraison 40,00 € et TVA
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN2473500 Func IHC (p) ELISA WB Rabbit IgG Connectez-vous pour afficher Polyclonal 2
1 ABIN609568 Func IHC (p) ELISA WB Rabbit IgG Connectez-vous pour afficher Polyclonal
1 ABIN198266 Func IHC (p) ELISA WB Rabbit IgG Connectez-vous pour afficher Polyclonal
1 ABIN260347 Func IHC (p) IHC ELISA WB Rabbit Connectez-vous pour afficher Polyclonal
1 ABIN640564 Func IHC (p) ELISA WB Rabbit IgG Connectez-vous pour afficher

General

Antigène Erythropoietin (EPO) Anticorps
Reactivité Humain
(339), (76), (43), (7), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Hôte Lapin
(192), (171), (15), (5), (3), (1)
Clonalité
Polyclonal
Conjugué Cet anticorp EPO est non-conjugé
(28), (21), (16), (10), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(249), (216), (66), (60), (57), (51), (30), (13), (10), (10), (7), (5), (4), (3), (2), (2), (2), (2), (2), (1), (1)
Pubmed 2 références disponible
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Détail du produit anti-EPO anticorps

Détail du antigène EPO Information d'application Stockage References for anti-EPO antibody (ABIN112633) Images
Specificité This antibody reacts with Erythropoietin, the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological levels of circulating erythrocyte mass. It is often used as a drug to treat anemia.
Purification Affinity Chromatography on Protein A
Immunogène CHO cell-derived, recombinant Human Erythropoietin.

Détail du antigène EPO

Détail du produit anti-EPO anticorps Information d'application Stockage References for anti-EPO antibody (ABIN112633) Images Haut de la page
Antigène
Autre désignation Erythropoietin / EPO (EPO Antibody Extrait)
Sujet Human erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.Synonyms: Epoetin
ID gène 2056
NCBI Accession NP_000790
UniProt P01588
Pathways Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity

Information d'application

Détail du produit anti-EPO anticorps Détail du antigène EPO Stockage References for anti-EPO antibody (ABIN112633) Images Haut de la page
Indications d'application ELISA: 0.5-1 μg/mL. Western Blot: 1-2 μg/mL (Reducing and Non-Reducing Conditions). Functional Assays: The ND50 was determined to be approximately 1-3 μg/mL, in thepresence of 0.3 units/mL of rhEpo, using a Human factor dependant cell line. Immunohistochemistry on Paraffin Sections: 15 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-EPO anticorps Détail du antigène EPO Information d'application References for anti-EPO antibody (ABIN112633) Images Haut de la page
Concentration 1.0 mg/mL
Buffer PBS, pH 7.2, 0.09 % Sodium Azide, 5 % Trehalose
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-EPO antibody (ABIN112633)

Détail du produit anti-EPO anticorps Détail du antigène EPO Information d'application Stockage Images Haut de la page
Background publications

Krystal: "A simple microassay for erythropoietin based on 3H-thymidine incorporation into spleen cells from phenylhydrazine treated mice." dans: Experimental hematology, Vol. 11, Issue 7, pp. 649-60, 1983

Kessler: "Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 115, Issue 6, pp. 1617-24, 1976