anti-Souris EPO anticorps pour Flow Cytometry

Recommended EPO Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Erythropoietin (EPO) Anticorps
  • EPO
  • EP
  • MVCD2
  • erythropoietin
  • EPO
  • epo
  • Epo
Reactivité
Souris
340
75
43
7
4
3
3
2
2
1
1
1
1
1
1
Hôte
Rat
192
172
14
5
3
1
Clonalité
Monoclonal
Conjugué
Cet anticorp EPO est non-conjugé
28
21
16
10
6
6
6
5
5
5
5
5
5
5
5
4
4
4
4
3
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
250
216
67
60
56
51
30
13
11
10
7
6
4
3
2
2
2
2
2
1
1
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N° du produit ABIN2664956
Produit non disponible pour cette région.

General

Antigène Erythropoietin (EPO) Anticorps
Reactivité Souris
(340), (75), (43), (7), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Hôte Rat
(192), (172), (14), (5), (3), (1)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp EPO est non-conjugé
(28), (21), (16), (10), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(250), (216), (67), (60), (56), (51), (30), (13), (11), (10), (7), (6), (4), (3), (2), (2), (2), (2), (2), (1), (1)
Pubmed 8 références disponible
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Détail du produit anti-EPO anticorps

Détail du antigène EPO Information d'application Stockage References for anti-EPO antibody (ABIN2664956) Images
Purification The antibody was purified by affinity chromatography.
Clone M029F6
Isotype IgG2b

Détail du antigène EPO

Détail du produit anti-EPO anticorps Information d'application Stockage References for anti-EPO antibody (ABIN2664956) Images Haut de la page
Antigène
Autre désignation EPO (EPO Antibody Extrait)
Sujet EPO is a glycoprotein that is glycosylated up to 40-60 % , which causes its molecular weight to vary from 30-34 kD depending on the carbohydrate percentage. Hypoxia induces erythropoiesis, and hypoxia inducible factor (HIF) is directly involved in EPO expression. HIF-Prolyl hydroxylase (HIF-PH) is a sensor of levels of iron, oxygen, and metabolic activity. High levels of HIF protein induces EPO production in the kidneys and liver, and mobilizes iron to support erythropoiesis. EPO has been used in the treatment of anemia associated with chronic kidney disease, treatment of cancer patients on chemotherapy, and antiviral HIV therapy.
Domaine de recherche Cancer, Organogenesis, Hematopoietic Progenitors, Angiogenesis
Pathways Signalistation JAK/STAT, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity

Information d'application

Détail du produit anti-EPO anticorps Détail du antigène EPO Stockage References for anti-EPO antibody (ABIN2664956) Images Haut de la page
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Stockage

Détail du produit anti-EPO anticorps Détail du antigène EPO Information d'application References for anti-EPO antibody (ABIN2664956) Images Haut de la page
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C
Stockage commentaire The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-EPO antibody (ABIN2664956)

Détail du produit anti-EPO anticorps Détail du antigène EPO Information d'application Stockage Images Haut de la page
Background publications

Alnaeeli, Wang, Piknova, Rogers, Li, Noguchi: "Erythropoietin in brain development and beyond." dans: Anatomy research international, Vol. 2012, pp. 953264, 2012

Kassouf, Hughes, Taylor, McGowan, Soneji, Green, Vyas, Porcher: "Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells." dans: Genome research, Vol. 20, Issue 8, pp. 1064-83, 2010

Paliege, Rosenberger, Bondke, Sciesielski, Shina, Heyman, Flippin, Arend, Klaus, Bachmann: "Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization." dans: Kidney international, Vol. 77, Issue 4, pp. 312-8, 2010

Sinclair, Coxon, McCaffery, Kaufman, Paweletz, Liu, Busse, Swift, Elliott, Begley: "Functional erythropoietin receptor is undetectable in endothelial, cardiac, neuronal, and renal cells." dans: Blood, Vol. 115, Issue 21, pp. 4264-72, 2010

Snow, Orkin: "Translational isoforms of FOG1 regulate GATA1-interacting complexes." dans: The Journal of biological chemistry, Vol. 284, Issue 43, pp. 29310-9, 2009

Chin, Yu, Beleslin-Cokic, Liu, Shen, Mohrenweiser, Noguchi: "Production and processing of erythropoietin receptor transcripts in brain." dans: Brain research. Molecular brain research, Vol. 81, Issue 1-2, pp. 29-42, 2000

Shoemaker, Mitsock: "Murine erythropoietin gene: cloning, expression, and human gene homology." dans: Molecular and cellular biology, Vol. 6, Issue 3, pp. 849-58, 1986

McDonald, Lin, Goldwasser: "Cloning, sequencing, and evolutionary analysis of the mouse erythropoietin gene." dans: Molecular and cellular biology, Vol. 6, Issue 3, pp. 842-8, 1986

Images

Détail du produit anti-EPO anticorps Détail du antigène EPO Information d'application Stockage References for anti-EPO antibody (ABIN2664956) Haut de la page
Supplier Images
Western Blotting (WB) image for anti-Erythropoietin (EPO) antibody (ABIN2664956) anti-Erythropoietin (EPO) antibody