Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Sélectionnez vos espèces et l'application
anti-Mouse (Murine) IL15 Anticorps:
anti-Human IL15 Anticorps:
anti-Rat (Rattus) IL15 Anticorps:
Vous arrivez à notre recherche pré-filtrée.
Human Monoclonal IL15 Primary Antibody pour CyTOF, FACS - ABIN4900389
Marra, Mathew, Grigoriadis, Wu, Kyle-Cezar, Watkins, Rashid, De Rinaldis, Hessey, Gazinska, Hayday, Tutt: IL15RA drives antagonistic mechanisms of cancer development and immune control in lymphocyte-enriched triple-negative breast cancers. dans Cancer research 2014
Show all 6 Pubmed References
Human Monoclonal IL15 Primary Antibody pour CyTOF, FACS - ABIN4900390
Ong, Hamid, Travers, Strickland, Al Kerithy, Boguniewicz, Leung: Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis. dans Journal of immunology (Baltimore, Md. : 1950) 2001
Show all 6 Pubmed References
Human Monoclonal IL15 Primary Antibody pour FACS - ABIN4897621
Anguille, Van Acker, Van den Bergh, Willemen, Goossens, Van Tendeloo, Smits, Berneman, Lion: Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner. dans PLoS ONE 2015
Show all 5 Pubmed References
Human Monoclonal IL15 Primary Antibody pour - ABIN1383961
Bernard, Harb, Mortier, Quéméner, Meloen, Vermot-Desroches, Wijdeness, van Dijken, Grötzinger, Slootstra, Plet, Jacques: Identification of an interleukin-15alpha receptor-binding site on human interleukin-15. dans The Journal of biological chemistry 2004
Show all 4 Pubmed References
Human Polyclonal IL15 Primary Antibody pour FACS, WB - ABIN4900388
Tejman-Yarden, Zlotnik, Lewis, Etzion, Chaimovitz, Douvdevani: Renal cells express a functional interleukin-15 receptor. dans Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2005
Show all 4 Pubmed References
Human Monoclonal IL15 Primary Antibody pour FACS - ABIN4897620
Ferlazzo, Pack, Thomas, Paludan, Schmid, Strowig, Bougras, Muller, Moretta, Münz: Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. dans Proceedings of the National Academy of Sciences of the United States of America 2004
Show all 4 Pubmed References
Human Polyclonal IL15 Primary Antibody pour Func, IHC (p) - ABIN2474939
Miller: T4 DNA polymerase (gene 43) is required in vivo for repair of gaps in recombinants. dans Journal of virology 1975
Show all 2 Pubmed References
Human Polyclonal IL15 Primary Antibody pour ELISA, WB - ABIN4324547
Schneider, Mohebiany, Ifergan, Beauseigle, Duquette, Prat, Arbour: B cell-derived IL-15 enhances CD8 T cell cytotoxicity and is increased in multiple sclerosis patients. dans Journal of immunology (Baltimore, Md. : 1950) 2011
T cells in chimpanzees infected with human immunodeficiency virus express surface interleukin-15.
CD3 (Montrer CD3 Anticorps)(-) CD8 (Montrer CD8A Anticorps)(+) NK cells play a vital role in controlling HIV-1 infection by producing high levels of IFN-gamma (Montrer IFNG Anticorps), and that IL-15 elicits IFN-gamma (Montrer IFNG Anticorps) production in this subpopulation of NK cells in HIV-1-infected chimpanzees. [Il-15, CD8 (Montrer CD8A Anticorps) antigen, IFN-gamma (Montrer IFNG Anticorps)]
results demonstrate that IL-15 and RANKL (Montrer TNFSF11 Anticorps) induce osteoclastogenesis synergistically, and IL-15 might play a novel and major role in destructive inflammatory bone diseases
This study provides mechanistic insight into how IL-15 controls the generation of memory CD8 (Montrer CD8A Anticorps) T cells and influences their trafficking and ability to take up residence within peripheral tissues.
findings extend understanding of the differential modes of action between IL-2 (Montrer IL2 Anticorps) and IL-15, and highlight how, although sharing the CD122 (Montrer IL2RB Anticorps)/CD132 (Montrer IL2RG Anticorps) receptor, they elicit such different immune actions
IL-15 induced by inflammatory signals in response to lymphodepletion drives lymphocyte responses, as memory CD8 (Montrer CD8A Anticorps) T cells proliferated in an IL-15-dependent manner.
these findings unveil a role for IL-15 as a critical mediator in defense against systemic candidiasis and hold promise for the design of IL-15-based antifungal immunotherapies.
developmental arrest of Natural killer cells results from a lack of IL-15 availability in the microenvironment.
IL-15 impacts butyrate-producing bacteria and lowers butyrate levels in the absence of overt pathology, which represent events that precede and promote intestinal inflammatory diseases.
endogenous IL-15 does not directly augment the pathogenesis of sepsis but enables the development of septic shock by maintaining NK cell numbers and integrity.
this study shows that IL-15-mediated control of the precursor population affects the development of virus-specific CD8 (Montrer CD8A Anticorps)+ T-cell memory
this study shows that unleashed trans-presentation of IL-15 on MyD88 (Montrer MYD88 Anticorps)-deficient fibroblastic reticular cells during viral infection fosters the activation of cytotoxic and non-cytotoxic group 1 innate lymphoid cells and accelerates clearance of the virus
High IL15 expression is associated with endometriosis.
IL-15 drives bystander activation of CD8 (Montrer CD8A Anticorps)+ T cells, which predicts disease progression in untreated HIV-1-infected patients and suggests that elevated IL-15 may also drive CD8 (Montrer CD8A Anticorps)+ T cell expansion that is linked to increased morbidity and mortality in treated patients
Sustained virologic response was significantly associated with IL15 rs10833 in chronic hepatitis C patients, treated with pegylated interferon-alpha (Montrer IFNA Anticorps) and ribavirin.
IL-15 mRNA and protein levels significantly increased in rhHBcAg stimulation group compared with non-stimulated group.
this work provides evidence that the sushi-IL-15Ralpha/IL-15 fusion protein RLI (Montrer ABCE1 Anticorps) enhances antitumor activity of anti-PD-1 (Montrer PDCD1 Anticorps) treatment and is a promising approach to stimulate host immunity
These results reveal a novel role of IL-7 (Montrer IL7 Anticorps) and IL-15 in maintaining human T cell function, provide an explanation for T cell dysfunction in humanized mice, and have significant implications for in vitro studies with human T cells.
This analysis revealed highly connected functional interaction networks with two candidate genes, IL15 and SEC14L5 highly enriched in networks. Overall, from these results, we concluded that these genes can be recommended as some of the potential targets for Post-Traumatic Stress Disorder.
These data support a potential role for IL-15 in the pathogenesis of HIV-associated immune activation.
Cutaneous T-cell lymphoma (CTCL (Montrer TSPYL2 Anticorps)) pathogenesis remains unknown, and there are no curative therapies. Our findings not only demonstrate a critical role for IL15-mediated inflammation in cutaneous T-cell lymphomagenesis, but also uncover a new oncogenic regulatory loop in CTCL (Montrer TSPYL2 Anticorps) involving IL15, HDAC1 (Montrer HDAC1 Anticorps), HDAC6 (Montrer HDAC6 Anticorps), and miR (Montrer MLXIP Anticorps)-21 that shows differential sensitivity to isotype-specific HDAC (Montrer HDAC3 Anticorps) inhibitors
Myokine IL-15 regulates the crosstalk of co-cultured porcine skeletal muscle satellite cells and preadipocytes.
results demonstrate that porcine reproductive and respiratory syndrome virus (PRRSV)infection could induce IL-15 production in macrophages/dendritic cells; data further show that upregulation of IL-15 by PRRSV requires PKC (Montrer FYN Anticorps) and NF-kappaB (Montrer NFKB1 Anticorps) pathways
IFN-gamma (Montrer IFNG Anticorps) targets the adipocyte to induce IL-15 expression, thus indicating a possible role for the adipocyte in the regulation of T-cell function and muscle metabolism during the innate immune response
When induced by IFN-gamma (Montrer IFNG Anticorps) or other inflammatory mediators, IL-15 may be a significant homeorhetic factor that mobilizes and directs energy away from the adipocyte to other cells during the acute phase of the inflammatory response.
Increased function and survival of IL-15-transduced dendritic cells are mediated by up-regulation of IL-15Ralpha and Bcl-2 (Montrer BCL2 Anticorps).
IL 15 generates a dramatic expansion of short-lived memory CD8 (Montrer CD8A Anticorps) T cells and natural killer in immunocompetent macaques and has long-term effects on the balance of CD4 (Montrer CD4 Anticorps)(+) and CD8 (Montrer CD8A Anticorps)(+) T cells.
These data suggest that therapeutic use of IL-15 in the setting of antiretroviral therapy might facilitate specific restoration of the CD4 (Montrer CD4 Anticorps) + T cell compartment.
IL-15 secretion significantly correlates with the up-regulated expression of CD4 (Montrer CD4 Anticorps) on memory CD4 (Montrer CD4 Anticorps) T cells that is associated with increased permissiveness to simian immunodeficiency virus infection.
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.