anti-Humain IL5 anticorps pour ELISpot

Recommended IL5 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Interleukin 5 (IL5) Anticorps
  • IL5
  • Il-5
  • IL-5
  • TRF
  • EDF
  • Pro-TRH
  • interleukin 5
  • Interleukin 5
  • interleukin 5 (colony-stimulating factor, eosinophil)
  • interleukin-5-like
  • thyrotropin-releasing hormone
  • IL5
  • Il5
  • IL-5
  • LOC100358075
  • TRH
Reactivité
Humain
191
139
27
20
17
3
2
2
1
1
1
Hôte
Rat
123
103
31
2
Clonalité
Monoclonal
Conjugué
Cet anticorp IL5 est non-conjugé
39
14
7
7
6
6
5
5
5
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
ELISpot, Neutralization (Neut), ELISA
125
124
107
23
22
13
11
10
10
9
9
7
6
6
5
4
4
4
2
2
1
1
Options
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N° du produit ABIN1177282
Produit non disponible pour cette région.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN2748992 ELISpot ICS Neut ELISA WB Mouse IgG1 Connectez-vous pour afficher QS-5
1 ABIN1177353 ELISpot ELISA Connectez-vous pour afficher
1 ABIN1448856 ELISpot Connectez-vous pour afficher

General

Antigène Interleukin 5 (IL5) Anticorps
Reactivité Humain
(191), (139), (27), (20), (17), (3), (2), (2), (1), (1), (1)
Hôte Rat
(123), (103), (31), (2)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp IL5 est non-conjugé
(39), (14), (7), (7), (6), (6), (5), (5), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISpot, Neutralization (Neut), ELISA
(125), (124), (107), (23), (22), (13), (11), (10), (10), (9), (9), (7), (6), (6), (5), (4), (4), (4), (2), (2), (1), (1)
Pubmed 2 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-IL5 anticorps

Détail du antigène IL5 Information d'application Stockage References for anti-IL5 antibody (ABIN1177282) Images
Marque BD Pharmingen™
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Stérilité 0.2 μm filtered
niveau d'endotoxine Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
Immunogène Recombinant Human IL-5
Clone JES1-5A10
Isotype IgG2a

Détail du antigène IL5

Détail du produit anti-IL5 anticorps Information d'application Stockage References for anti-IL5 antibody (ABIN1177282) Images Haut de la page
Antigène
Autre désignation IL-5 (IL5 Antibody Extrait)
Sujet The JES1-5A10 monoclonal antibody specifically binds to the human Interleukin-5 (IL-5). IL-5 is a cytokine that is also known as T-cell replacing factor (TRF), Eosinophil differentiation factor (EDF), and B cell differentiation factor I. IL-5 is produced by T cells, mast cells, and eosinophils. IL-5 controls the generation, differentiation, activation and localization of eosinophils. IL-5 also activates and promotes the differentiation of basophils. IL-5 plays an important role in regulating cell-mediated immunity against parasitic infections and some tumors. High level IL-5 production is involved in some allergic diseases including asthma. IL-5 exerts its biological effects by binding to and signaling through high-affinity heterodimeric IL-5 receptors comprised of transmembrane IL-5 receptor alpha (IL-5Ralpha, aka, CD125) and beta common (betac, aka, CD131) chains. The betac chain serves as the common signaling subunit for the IL-5 receptor heterodimer as well as for the heterodimeric IL-3 and GM-CSF receptors. The immunogen used to generate the JES1-5A10 hybridoma was recombinant human IL-5. The JES1-5A10 antibody has been reported to cross react with IL-5 from rhesus monkey. This is a neutralizing antibody.
Synonyms: EDF, Eosinophil differentiation factor, TRF, T-cell replacing factor
Domaine de recherche Cancer
Pathways Signalistation JAK/STAT, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour

Information d'application

Détail du produit anti-IL5 anticorps Détail du antigène IL5 Stockage References for anti-IL5 antibody (ABIN1177282) Images Haut de la page
Restrictions For Research Use only

Stockage

Détail du produit anti-IL5 anticorps Détail du antigène IL5 Information d'application References for anti-IL5 antibody (ABIN1177282) Images Haut de la page
Format Liquid
Concentration 1.0 mg/mL
Buffer No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
Agent conservateur Azide free
Stock 4 °C
Stockage commentaire Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

References for anti-IL5 antibody (ABIN1177282)

Détail du produit anti-IL5 anticorps Détail du antigène IL5 Information d'application Stockage Images Haut de la page
Produit citée dans:

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." dans: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, 1992

Butterfield, Leiferman, Abrams, Silver, Bower, Gonchoroff, Gleich: "Elevated serum levels of interleukin-5 in patients with the syndrome of episodic angioedema and eosinophilia." dans: Blood, Vol. 79, Issue 3, pp. 688-92, 1992