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Human Leptin Kit ELISA pour Sandwich ELISA - ABIN625035
Jiménez-Pavón, Ortega, Artero, Labayen, Vicente-Rodriguez, Huybrechts, Moreno, Manios, Béghin, Polito, De Henauw, Sjöström, Castillo, González-Gross, Ruiz: Physical activity, fitness, and serum leptin concentrations in adolescents. dans The Journal of pediatrics 2012
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Mouse (Murine) Leptin Kit ELISA pour Sandwich ELISA - ABIN625156
Jiao, Feng, Ma, Nie, Paul, Li, Xu: Constitutive Activation of IKKβ in Adipose Tissue Prevents Diet-Induced Obesity in Mice. dans Endocrinology 2011
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Rat (Rattus) Leptin Kit ELISA pour Sandwich ELISA - ABIN625206
Zhang, Wang, Long, Wang, Li, Gao, Tian: Alteration of sweet taste in high-fat diet induced obese rats after 4 weeks treatment with exenatide. dans Peptides 2013
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Human Leptin Kit ELISA pour Sandwich ELISA - ABIN411318
Masuzaki, Ogawa, Sagawa, Hosoda, Matsumoto, Mise, Nishimura, Yoshimasa, Tanaka, Mori, Nakao: Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. dans Nature medicine 1997
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Pig (Porcine) Leptin Kit ELISA pour Sandwich ELISA - ABIN415853
Walsh, Sweeney, Bahar, ODoherty: Multi-functional roles of chitosan as a potential protective agent against obesity. dans PLoS ONE 2013
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Rat (Rattus) Leptin Kit ELISA pour Sandwich ELISA - ABIN416359
Zhang, Liu, Wang, Sun, Su, Zhang, Li, Yang: Puerarin improves insulin resistance and modulates adipokine expression in rats fed a high-fat diet. dans European journal of pharmacology 2010
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Human Leptin Kit ELISA pour Sandwich ELISA - ABIN612724
Karakus, Gelisgen, Topcuoglu, Guralp, Topcuoglu, Simsek, Uludag, Uzun: The effects of 17β-estradiol plus drospirenone on anthropometric and biochemical measures of adiposity in menopausal women. dans Archives of gynecology and obstetrics 2012
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Mouse (Murine) Leptin Kit ELISA pour Sandwich ELISA - ABIN365180
Olea, Ribeiro, Gallego-Martin, Yubero, Rigual, Masa, Obeso, Conde, Gonzalez: The Carotid Body Does Not Mediate the Acute Ventilatory Effects of Leptin. dans Advances in experimental medicine and biology 2015
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Rat (Rattus) Leptin Kit ELISA pour Sandwich ELISA - ABIN365192
Kumar, Kaur: Intermittent fasting dietary restriction regimen negatively influences reproduction in young rats: a study of hypothalamo-hypophysial-gonadal axis. dans PLoS ONE 2013
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Cow (Bovine) Leptin Kit ELISA pour Competition ELISA - ABIN364601
Osorio, Trevisi, Ballou, Bertoni, Drackley, Loor: Effect of the level of maternal energy intake prepartum on immunometabolic markers, polymorphonuclear leukocyte function, and neutrophil gene network expression in neonatal Holstein heifer calves. dans Journal of dairy science 2013
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neuronal Rap1 (Montrer TERF2IP Kits ELISA) critically regulates leptin sensitivity
Upregulation of leptin levels in both the vessel wall and the circulation after vessel injury promoted the migration of Sca-1 (Montrer Ly6a Kits ELISA)(+) progenitor cells via leptin receptor (Montrer LEPR Kits ELISA)-dependent signal transducer and activator of transcription 3 (Montrer STAT3 Kits ELISA)- Rac1/Cdc42 (Montrer CDC42 Kits ELISA)-ERK (Montrer EPHB2 Kits ELISA) (extracellular signal-regulated kinase)-FAK (Montrer PTK2 Kits ELISA) pathways, which enhanced neointimal formation.
Depletion of CLPABP disturbed the normal subcellular localization of HuR (Montrer ELAVL1 Kits ELISA) to stress granules, and overexpression of CLPABP induced instability of leptin mRNA by inhibiting HuR (Montrer ELAVL1 Kits ELISA) function.
These results confirm and extend the previous evidence that LEP has a general and important role in the response of mammalian cells to irradiation.
leptin is involved in the proliferation and activation of microglia, which in turn enhances the development of neuropathic pain after avulsion of the cervical roots.
Suggest that intact endothelial leptin signaling limits neointima formation and that obesity represents a state of endothelial leptin resistance.
these studies demonstrate marked differences in the acute insulin (Montrer INS Kits ELISA)-independent effects by which leptin reverses fasting hyperglycemia and ketoacidosis in a rodent model of DKA versus the chronic pleotropic effects by which leptin reverses hyperglycemia in a non-DKA rodent model of T1D.
High fat diet attenuates leptin signaling throughout the brain, but some brain regions maintain their ability to sense leptin. Weight loss restores leptin sensing to some degree in most (but not all) brain regions, while other brain regions display hypersensitivity to leptin following weight loss
CNS-specific Tak1 (Montrer NR2C2 Kits ELISA) deletion prevented ER-stress-induced hypothalamic leptin resistance and hyperphagic obesity under a high-fat diet (HFD). Thus, TAK1 (Montrer NR2C2 Kits ELISA) is a crucial regulator of ER stress in vivo, which could be a target for alleviation of ER stress and its associated disease conditions.
These data further implicate IL-6 (Montrer IL6 Kits ELISA) in fatty liver disease modulation in the context of DIO, and indicate that continuous stimulation with IL-6 (Montrer IL6 Kits ELISA) attenuates the IL-6 (Montrer IL6 Kits ELISA)-receptor response, which is associated with high serum levels of leptin.
disturbance of reciprocal relationships between adipsin (Montrer CFD Kits ELISA) and leptin in obesity is associated with the development of insulin (Montrer INS Kits ELISA) resistance
The leptin SNP rs7799039 (G2548A) was associated to high sensitivity-C-reactive protein (Montrer CRP Kits ELISA) levels at both ages.
Leptin-induced transphosphorylation of vascular endothelial growth factor receptor (Montrer RYK Kits ELISA) increases Notch (Montrer NOTCH1 Kits ELISA) and stimulates endothelial cell angiogenic transformation
High leptin/adiponectin (Montrer ADIPOQ PLURAL_@2013@) ratio in pregnancy, particularly in those with gestational diabetes, is associated with an unfavorable CVD risk profile during follow-up.
leptin-adiponectin (Montrer ADIPOQ PLURAL_@2013@) imbalance, as reflected by an increase in leptin/adiponectin (Montrer ADIPOQ PLURAL_@2013@) ratio, was found to be a better diagnostic biomarker for MS than leptin or adiponectin (Montrer ADIPOQ PLURAL_@2013@) alone.
Leptin knockdown suppressed MUC5AC production and secretion induced by IL-13 (Montrer IL13 Kits ELISA) in human bronchial epithelial cells.
Leptin levels increase significantly within 3 months of fetal pancreatic stem cell transplant in patients with type 1 diabetes mellitus.
High leptin expression is associated with lymph node metastasis in breast cancer.
High leptin serum level is associated with lung cancer.
IL-23 (Montrer IL23A Kits ELISA) R (rs7517847) and LEP (rs7799039) polymorphisms were associated with an increased risk but not affecting the clinical presentation of HCC (Montrer FAM126A Kits ELISA) among Egyptian patients
study has allowed a transcriptional characterization of LEP and LEPR (Montrer LEPR Kits ELISA) isoforms on a range of tissues. Their expression patterns seem to indicate that both molecules develop peripheral roles apart from their known hypothalamic signal transduction function
The lack of effect of heat stress on the expression of leptin suggests that this peptide may not be involved in the reduction of feed intake of HS acclimated pigs.
A high variability of the LEP was detected in the different analysed populations providing new data for the existence of two domestication centres in Asia.
The presence of leptin and ObR (Montrer LEPR Kits ELISA)-b varies across parities and is more intense in the uterus, ovaries and hypothalamus of females that were cycling before culling than in those having cystic ovaries.
Studied 3'UTR (Montrer UTS2R Kits ELISA) leptin polymorphism regulatory sequences' affect on gene expression and their association with production traits.
These results suggest that LEPR, MC4R, PIK3C3 and VRTN are useful markers for accurately predicting breeding values in Duroc pigs.
Data showing changes in expression patterns of LEP/LEPR (Montrer LEPR Kits ELISA) in endometrium/chorioallantoic membrane during placentation/fetal development suggest role for LEP/LEPR (Montrer LEPR Kits ELISA) complex at early stages of pregnancy, possibly affecting the attachment process.
Another funning discovery is ob-Rb (Montrer LEPR Kits ELISA) mRNA in porcine endometrium was mainly negative-regulated by leptin
Characterization of a distinctive pattern of periovulatory leptin secretion and its relationship with ovulation rate and luteal function in swine with obesity/leptin resistance
Leptin and leptin receptor (Montrer LEPR Kits ELISA) are expressed in porcine luteal cells, and there is a modulatory effect of LH, estradiol (E) and progesterone (P) on leptin mRNA expression as well as E and P on leptin secretion by those cells obtained in early pregnancy.
Consistent with this, leptin enhanced GnRH (Montrer GNRH1 Kits ELISA)-induced secretion of LH measured by ELISA. We suggest that leptin enhances membrane expression of voltage-gated Na(+) and Ca(2 (Montrer CA2 Kits ELISA)+) channels, which results in a modulation of the action potential properties and an increase in hormone release from gonadotropes.
The effects of a single nucleotide polymorphism of leptin on weight gain and body composition are reported.
A leptin SNP (LEPg.978) was significantly associated with a weight at one year.
The results of this study suggest that leptin physiology could be a candidate for mechanisms that contribute to feed intake and feed efficiency variation in beef cattle.
Leptin concentrations could be a useful physiological marker for growth and feed efficiency of finishing beef cattle.
Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin-NPY (Montrer NPY Kits ELISA) and insulin (Montrer INS Kits ELISA) signaling pathways.
Leptin R25C genotype impacted most traits associated with fatness.
The absence of A80V polymorphism (C --> T at position 95691973 bp of leptin gene) has been established in the genotypes of Ayrshire cattle as compared to Holstein cattle.
Data indicate that increased body weight gain during juvenile development accelerates sexual maturation in heifers, coincident with reciprocal changes in circulating concentrations of leptin and hypothalamic neuropeptide Y (NPY (Montrer NPY Kits ELISA)) release.
SNP LEP significantly affected milk, protein and fat yield (P<0.05), and age at first calving (P<0.01) in analyzed population of cows. SNP LEPR (Montrer LEPR Kits ELISA)/T945M affected significantly calving interval (P<0.01) only
polymorphisms of the LEP gene might be important genetic factors influencing growth traits, and these genetic markers may be useful for future marker-assisted selection programs in goat breeding and production
study suggests that increased CSF (Montrer CSF2 Kits ELISA) leptin, likely from blood-brain barrier breakdown, combined with elevated serum GH and IGF-1 (Montrer IGF1 Kits ELISA) after traumatic brain injury, leads to accelerated fracture healing
We conclude that offspring from mothers consuming a high fat diet exhibit an adverse cardiovascular profile in adulthood because of altered central hypothalamic sensitivity to leptin and ghrelin (Montrer GHRL Kits ELISA).
Niacin Reduces serum level and adipose mRNA expression of leptin and up-regulates PPARgamma (Montrer PPARG Kits ELISA) and CD36 (Montrer CD36 Kits ELISA) mRNA expression in hypercholesterolemic rabbits.
Positive correlations were found between leptin and total lipids, triglycerides, VLDLs, Total-Chol, and LDLs.
Leptin metabolism in obese ponies following a return to free feeding after a period of food deprivation is reported.
Plasma levels of leptin (as well as glucose, insulin, and growth hormone) are highly correlated with the duration of winter anovulatory phase.
GHRL (Montrer GHRL Kits ELISA), LEP, ADIP (Montrer SSX2IP Kits ELISA), INS (Montrer INS Kits ELISA) and CORT (Montrer CORT Kits ELISA) concentrations were measured using radioimmunoassay
positive correlation between leptin and estradiol led us to suggest that leptin hormone plays an important role in ovulation of the first postpartum estrus in mares
The effects of exogenous human kisspeptin-10 (KP10) were studied on three important adipokines, namely, adiponectin (Montrer ADIPOQ Kits ELISA), leptin, and resistin (Montrer RETN Kits ELISA) in a set of four chair-restraint habituated intact adult male rhesus monkeys.
results do not support a role for reduced leptin secretion in anovulation induced by dietary restriction
This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
, leptin (murine obesity homolog)
, leptin (obesity homolog, mouse)
, obese protein
, obese, mouse, homolog of