anti-Chien SOCS1 anticorps pour Enzyme Immunoassay

Recommended SOCS1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Suppressor of Cytokine Signaling 1 (SOCS1) Anticorps
  • socs1
  • zgc:91868
  • jab
  • cis1
  • ssi1
  • tip3
  • cish1
  • ssi-1
  • socs-1
  • SOCS1
  • LOC100228306
  • socs1b
  • CIS1
  • CISH1
  • JAB
  • SOCS-1
  • SSI-1
  • SSI1
  • TIP3
  • Cish1
  • Cish7
  • Socs-1
  • suppressor of cytokine signaling 1a
  • suppressor of cytokine signaling 1
  • suppressor of cytokine signaling 1-like protein
  • socs1a
  • socs1
  • SOCS1
  • LOC100228306
  • socs1-b
  • Socs1
Épitope
C-Term
55
22
15
7
5
3
3
2
2
2
1
1
1
1
1
1
1
1
Reactivité
Boeuf (Vache), Chien, Humain, Souris, Rat (Rattus)
161
96
76
11
9
8
6
5
4
4
3
1
Hôte
Chèvre
143
19
13
Clonalité
Polyclonal
Conjugué
Cet anticorp SOCS1 est non-conjugé
11
7
6
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
148
54
37
32
13
13
12
6
5
5
4
2
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N° du produit ABIN5552634
357,50 €
Plus frais de livraison 40,00 € et TVA

General

Antigène Suppressor of Cytokine Signaling 1 (SOCS1) Anticorps
Épitope C-Term
(55), (22), (15), (7), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Boeuf (Vache), Chien, Humain, Souris, Rat (Rattus)
(161), (96), (76), (11), (9), (8), (6), (5), (4), (4), (3), (1)
Hôte Chèvre
(143), (19), (13)
Clonalité
Polyclonal
Conjugué Cet anticorp SOCS1 est non-conjugé
(11), (7), (6), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(148), (54), (37), (32), (13), (13), (12), (6), (5), (5), (4), (2)
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Détail du produit anti-SOCS1 anticorps

Détail du antigène SOCS1 Information d'application Stockage Images
Séquence C-VLRDYLSSFP FQI
Specificité Recognizes Suppressor Of Cytokine Signaling 1 (SOCS1) at C-term.
Réactivité croisée (Details) Species reactivity (expected):Rat, Canine (Dog) and Bovine.
Species reactivity (tested):Human, Mouse.
Purification Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogène Synthetic peptide from the C-Terminus of Human SOCS1 (NP_003736.1). Genename: SOCS1

Détail du antigène SOCS1

Détail du produit anti-SOCS1 anticorps Information d'application Stockage Images Haut de la page
Antigène
Autre désignation SOCS1 (SOCS1 Antibody Extrait)
Sujet SOCS1 represents a family of proteins that regulates responses to cytokines. The SOCS family comprises at least 8 members, SOCS1 to SOCS7 and CIS (cytokine inducible SH2 containing protein). Structurally, the SOCS proteins are composed of an N terminal region of variable length and amino acid composition, a central SH2 domain, and a previously unrecognized C terminal motif named the SOCS box. SOCS1 (also known as Janus kinase binding protein and STAT induced STAT inhibitor 1) was isolated independently by its ability to interact with Janus kinase 2 in a 2 hybrid screen and on the basis of antigenic similarity with the SH2 domain of STAT3. SOCS 1 inhibition of signal transduction appears to occur by binding to and inhibiting the catalytic activity of members of JAK family of cytoplasmic kinases (direct JAK2 kinase inhibition). Biochemical characterization as well as gene disruption studies indicate that SOCS1 is an important negative regulator of JAK-STAT signal pathway.Synonyms: JAB, JAK-binding protein, SOCS-1, SSI-1, SSI1, STAT-induced STAT inhibitor 1, Suppressor of cytokine signaling 1, TIP-3, TIP3, Tec-interacting protein 3
ID gène 8651
NCBI Accession NP_003736
UniProt O15524
Domaine de recherche Chromatin and Nuclear Signaling, Cytokines, Signaling
Pathways Signalistation JAK/STAT, Interferon-gamma Pathway, Signalisation TLR, Response to Growth Hormone Stimulus

Information d'application

Détail du produit anti-SOCS1 anticorps Détail du antigène SOCS1 Stockage Images Haut de la page
Indications d'application Peptide ELISA: Limit Dilution: 1/4000. Western blot: 1-3 μg/mL. In transfected HEK293 transiently expressing human SOCS1 bandsof approx.30 kDa and 20 kDa are observed. These bands are not observed in thenon-transfected HEK293. A similar pattern is observed in Mouse Spleen lysates. Thecalculated molecular size is 23.0 kDa according to Human NP_003736.1 and 23.0 kDa
Restrictions For Research Use only

Stockage

Détail du produit anti-SOCS1 anticorps Détail du antigène SOCS1 Information d'application Images Haut de la page
Concentration 0.5 mg/mL
Buffer Tris saline buffer, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.