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Aperçu des produits pour anti-SRC (SRC) Anticorps

Full name:
anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) Anticorps (SRC)
Chez sont 433 V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) Anticorps de 29 de différents fournisseurs disponibles. De plus, nous expédions SRC Protéines (20) et SRC Kits (18) et beaucoup plus de produits pour cette protéine. Un total de 496 SRC produits sont actuellement listés.
ASV, AW259666, c-Src, C-src1, CG7524, D-src, D-Src64B, Dmel\CG7524, DmHD-358, Dm SRC1, dsrc, Dsrc64, Dsrc64B, HD-358, MRE5, p60-Src, PP60C-SCR, pp60c-src, SDR, src, SRC1, src64, SRC 64B, src64b

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anti-SRC Anticorps mieux référencés

  1. Human Polyclonal SRC Primary Antibody pour WB - ABIN1881832 : Kieslinger, Hiechinger, Dobreva, Consalez, Grosschedl: Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner. dans Cell stem cell 2010 (PubMed)
    Show all 5 references for ABIN1881832

  2. Human Polyclonal SRC Primary Antibody pour FACS, IF - ABIN1881833 : Pradhan, Alrehani, Patel, Khatlani, Vijayan: Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen. dans The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN1881833

  3. Human Polyclonal SRC Primary Antibody pour ICC, IF - ABIN408484 : Yilmaz, Oztay, Kayalar: Dasatinib attenuated bleomycin-induced pulmonary fibrosis in mice. dans Growth factors (Chur, Switzerland) 2016 (PubMed)
    Show all 4 references for ABIN408484

  4. Human Polyclonal SRC Primary Antibody pour IHC, ELISA - ABIN1533006 : Xu, Harrison, Eck: Three-dimensional structure of the tyrosine kinase c-Src. dans Nature 1997 (PubMed)
    Show all 2 references for ABIN1533006

  5. Human Polyclonal SRC Primary Antibody pour IHC, ELISA - ABIN1531972 : Benes, Wu, Elia, Dharia, Cantley, Soltoff: The C2 domain of PKCdelta is a phosphotyrosine binding domain. dans Cell 2005 (PubMed)
    Show all 2 references for ABIN1531972

  6. Human Monoclonal SRC Primary Antibody pour IF, WB - ABIN387822 : Chen, Li, Zhang, Yi, Chen, Wang, Zhang: Src-stimulated IRTKS phosphorylation enhances cell migration. dans FEBS letters 2011 (PubMed)
    Show all 2 references for ABIN387822

  7. Human Polyclonal SRC Primary Antibody pour ELISA, WB - ABIN1533137 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... dans Nature 2002 (PubMed)

  8. Cow (Bovine) Polyclonal SRC Primary Antibody pour WB - ABIN2779668 : Pechkovsky, Scaffidi, Hackett, Ballard, Shaheen, Thompson, Thannickal, Knight: Transforming growth factor beta1 induces alphavbeta3 integrin expression in human lung fibroblasts via a beta3 integrin-, c-Src-, and p38 MAPK-dependent pathway. dans The Journal of biological chemistry 2008 (PubMed)

Plus d’anticorps contre SRC partenaires d’interaction

Mouse (Murine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line has been reported.

  2. Data show that the essential oil (EO) decreased focal adhesion and invadopodia formation which was accompanied by a drastic downregulation of focal adhesion kinase (FAK) and proto-oncogene protein Src.

  3. miR (Montrer MLXIP Anticorps)-222-3p serves as an inhibitor of osteoclastogenesis and c-Src mediates its inhibition of cathepsin K (Montrer CTSK Anticorps) and TRAP.

  4. results suggest that LPS (Montrer TLR4 Anticorps)-stimulated macrophage mediators attenuate both FAK (Montrer PTK2 Anticorps) and Src activations in osteoblast, suggesting a novel role for TNFalpha (Montrer TNF Anticorps) on osteoblast performance

  5. Src has a role in priming Pyk2 (Montrer PTK2B Anticorps) (but not FAK (Montrer PTK2 Anticorps)) phosphorylation and subsequent activation downstream of integrins

  6. Heritable pulmonary arterial hypertension (PAH) results from increased SRC activation, cellular contraction, and vascular resistance, but antagonism of HTR2B prevents SRC phosphorylation and development of PAH.

  7. Periodic axial motility of epithelial basal cell projections is controlled by c-Src.

  8. mutation of the five Src-modified residues to aspartate but not phenylalanine allows Runx1 (Montrer RUNX1 Anticorps) to increase Cebpa (Montrer CEBPA Anticorps) and granulocyte colony formation by Runx1 (Montrer RUNX1 Anticorps)-deleted murine marrow.

  9. This study provides an additional mechanistic link between Angiotensin II and vasoconstriction via SFK-enhanced MLC phosphorylation in smooth muscle cells.

  10. Src/Syk (Montrer SYK Anticorps)-dependent signalling stabilises platelet adhesion to podoplanin (Montrer PDPN Anticorps)

Fruit Fly (Drosophila melanogaster) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo

  2. that Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway previously shown to promote axon retraction

  3. Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation.

  4. a novel essential role for Src in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo.

  5. Data show that the actin-Capping Protein (Montrer TMOD4 Anticorps) (CP) alphabeta heterodimer, which regulates actin (Montrer ACTB Anticorps) filament (F-actin (Montrer ACTB Anticorps)) polymerization, limits Src-induced apoptosis or tissue overgrowth by restricting JNK (Montrer MAPK8 Anticorps) activation.

  6. Dumbfounded/Neph1 (Montrer NEPH1 Anticorps), a key diaphragm constituent, is a target of the Src kinase (Montrer CSK Anticorps) Src64B. Loss of Src64B activity leads to a reduction in the number of diaphragms, and this effect is in part mediated by loss of Dumbfounded/Neph1 (Montrer NEPH1 Anticorps) tyrosine phosphorylation.

  7. Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B in the developing embryonic central nervous system.

  8. E4orf4 has a role in inducing PP2A (Montrer PPP2R2B Anticorps)- and Src-dependent cell death while inhibiting classic apoptosis pathways in Drosophila melanogaster

  9. Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified.

  10. Src64B overexpression induced the formation of specialized haemocytes (lamellocytes), but had no effect on circulating plasmatocyte concentration. Src64B overexpression induced F-actin (Montrer ACTB Anticorps) formation and Jun kinase (Montrer MAPK9 Anticorps) activation in plasmatocytes.

Human V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line has been reported.

  2. Stress-resistant translation of c-Src mRNA is mediated by eIF2A (Montrer EIF2S1 Anticorps).

  3. IL-1beta (Montrer IL1B Anticorps) constitutes a new step in the CFTR (Montrer CFTR Anticorps) signaling pathway, located upstream of c-Src, which is stimulated in cells with impaired CFTR (Montrer CFTR Anticorps) activity

  4. HDAC1 (Montrer HDAC1 Anticorps)- and SRC-mediated phosphorylation of RUNX3 (Montrer RUNX3 Anticorps) induced by oxidative stress is associated with the cytoplasmic localization of RUNX3 (Montrer RUNX3 Anticorps) and can lead to RUNX3 (Montrer RUNX3 Anticorps) inactivation and carcinogenesis.

  5. mechanistic studies, inhibition of SRC and PKCdelta (Montrer PKCd Anticorps) completely ablated the ability of MDA-7/IL-24 (Montrer IL24 Anticorps) to reduce the Bcl-x(L (Montrer BCL2L1 Anticorps))/(s) mRNA ratio and cell viability. These findings show that Bcl-x (Montrer BCL2L1 Anticorps)(s) expression is an important mediator of MDA-7/IL-24 (Montrer IL24 Anticorps)-induced cytotoxicity requiring the SRC/PKCdelta (Montrer PKCd Anticorps) signaling axis in NSCLC cells.

  6. Caspase-8 (Montrer CASP8 Anticorps) is phosphorylated on Tyr380 in a Src kinase (Montrer CSK Anticorps) dependent manner and this phosphorylation is required for transformation and it is enhanced by hypoxic conditions.

  7. data suggest that activation of FAK by the interaction between CD133 and Src promotes cell migration, providing clues to understand the migratory mechanism of CD133(+) tumor cells.

  8. results definitively show that LMP1 (Montrer PDLIM7 Anticorps) promotes IRF4 (Montrer IRF4 Anticorps) tyrosine phosphorylation and markedly stimulates its transcriptional activity through recruiting Src via P85

  9. FAK (Montrer PTK2 Anticorps)/SRC and paxillin (Montrer PXN Anticorps) play a role in the pathophysiological aspects of mobile tongue squamous cell carcinoma and could constitute therapeutic targets

  10. Data indicate that SRY-box 3 transcription factor SOX-3 (Montrer SOX3 Anticorps) targets Src kinase (Montrer CSK Anticorps) in epithelial ovarian cancer (EOC) cells.

Cow (Bovine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. RhoA (Montrer RHOA Anticorps) and membrane fluidity mediates the spatially polarized Src/FAK (Montrer PTK2 Anticorps) activation in response to shear stress.

  2. AngII activates PKD via a mechanism involving Src family kinases and PKC, to underlie increased aldosterone production.

  3. The Src gene possibly contributed to conducting association analysis and can be recognized as genetic marker in milk production traits and other performance for animal breeding and genetics.

  4. src has a role in activation of 5'-AMP (Montrer TMPRSS5 Anticorps)-activated kinase during hypoxia-reoxygenation of bovine aortic endothelial cells

  5. results indicate that integrin engagement disrupts VE-cadherin-containing adherens junctions via the activation of Src, but not Ras, possibly as a result of modulation of the actin network

  6. These results suggest that TGF-beta1 (Montrer TGFB1 Anticorps)-induced monolayer permeability involves focal adhesion and cytoskeletal rearrangement through both FAK (Montrer PTK2 Anticorps)/Src-dependent and -independent pathways.

Pig (Porcine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. The findings are consistent with previous studies that indicate a link between Na,K-ATPase (Montrer ATP1A1 Anticorps) activity and SFK signaling.

  2. Src kinase (Montrer CSK Anticorps) mediates hypoxia-induced caspase-1 (Montrer CASP1 Anticorps) activation in the cerebral cortex of newborn piglets

  3. Expression of mutant alpha1 Na/K-ATPase (Montrer ATP1A1 Anticorps) defective in conformational transition attenuates Src-mediated signal transduction

  4. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

SRC profil antigène

Antigen Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with SRC

  • v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC) anticorps
  • proto-oncogene tyrosine-protein kinase src (AaeL_AAEL002471) anticorps
  • proto-oncogene tyrosine-protein kinase src (CpipJ_CPIJ010659) anticorps
  • Rous sarcoma oncogene (Src) anticorps
  • Src oncogene at 64B (Src64B) anticorps
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (SRC) anticorps
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (Src) anticorps
  • v-src sarcoma viral oncogene (SRC) anticorps
  • ASV anticorps
  • AW259666 anticorps
  • c-Src anticorps
  • C-src1 anticorps
  • CG7524 anticorps
  • D-src anticorps
  • D-Src64B anticorps
  • Dmel\CG7524 anticorps
  • DmHD-358 anticorps
  • Dm SRC1 anticorps
  • dsrc anticorps
  • Dsrc64 anticorps
  • Dsrc64B anticorps
  • HD-358 anticorps
  • MRE5 anticorps
  • p60-Src anticorps
  • PP60C-SCR anticorps
  • pp60c-src anticorps
  • SDR anticorps
  • src anticorps
  • SRC1 anticorps
  • src64 anticorps
  • SRC 64B anticorps
  • src64b anticorps

Protein level used designations for SRC

proto-oncogene tyrosine-protein kinase SRC , proto-oncogene tyrosine-protein kinase src , neuronal proto-oncogene tyrosine-protein kinase Src , p60-Src , proto-oncogene c-Src , CG7524-PB , CG7524-PC , CG7524-PD , CG7524-PE , CG7524-PF , CG7524-PG , CG7524-PH , CG7524-PI , CG7524-PJ , Src proto oncogene sequence , Src64B-PB , Src64B-PC , Src64B-PD , Src64B-PE , Src64B-PF , Src64B-PG , Src64B-PH , Src64B-PI , Src64B-PJ , mRNA-like ncRNA in embryogenesis 5 , proto-oncogene tyrosine-protein kinase Src , protooncogene SRC, Rous sarcoma , tyrosine kinase pp60c-src , tyrosine-protein kinase SRC-1 , Rous sarcoma oncogene , c-Src , pp60c-src , tyrosine protein kinase c-src , tyrosine protein kinase pp60-c-src , v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog , src oncogene , v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog , non-tyrosine protein kinase

458229 Pan troglodytes
5574802 Aedes aegypti
6043642 Culex quinquefasciatus
20779 Mus musculus
48973 Drosophila melanogaster
6714 Homo sapiens
83805 Rattus norvegicus
485864 Canis lupus familiaris
535742 Bos taurus
100154503 Sus scrofa
396442 Gallus gallus
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