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Aperçu des produits pour anti-STAT1 (STAT1) Anticorps

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anti-Signal Transducer and Activator of Transcription 1, 91kDa Anticorps (STAT1)
Chez sont 604 Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Anticorps de 36 de différents fournisseurs disponibles. De plus, nous expédions STAT1 Kits (46) et STAT1 Protéines (21) et beaucoup plus de produits pour cette protéine. Un total de 715 STAT1 produits sont actuellement listés.
2010005J02Rik, AA408197, CANDF7, DD6G4-4, dZ182H3.3, H2RSP, IMUP, IMUP-1, IMUP-2, ISGF-3, si:by51f19.1, si:by134g18.2, si:dz73o4.2, si:dz182h3.3, si:dz199m19.1, STAT, STAT1, STAT4, STAT91, XStat1
afficher tous les anticorps Gène GeneID UniProt
STAT1 72275  
STAT1 25124  
STAT1 6772 P42224

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anti-STAT1 Anticorps mieux référencés

  1. Human Polyclonal STAT1 Primary Antibody pour EIA, IHC (p) - ABIN358231 : Garcin, Marq, Iseni, Martin, Kolakofsky: A short peptide at the amino terminus of the Sendai virus C protein acts as an independent element that induces STAT1 instability. dans Journal of virology 2004 (PubMed)
    Show all 5 references for ABIN358231

  2. Human Polyclonal STAT1 Primary Antibody pour EIA, IF - ABIN500815 : Leonard, OShea: Jaks and STATs: biological implications. dans Annual review of immunology 1998 (PubMed)
    Show all 4 references for ABIN500815

  3. Human Monoclonal STAT1 Primary Antibody pour IHC (p), IP - ABIN269146 : Kovarik, Boudny, Kocak, Lauerova, Fait, Vagundova: Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. dans International journal of molecular medicine 2003 (PubMed)
    Show all 2 references for ABIN269146

  4. Human Polyclonal STAT1 Primary Antibody pour IF, IHC - ABIN1533008 : Durbin, Hackenmiller, Simon, Levy: Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. dans Cell 1996 (PubMed)
    Show all 2 references for ABIN1533008

  5. Cow (Bovine) Polyclonal STAT1 Primary Antibody pour WB - ABIN2777895 : Battle, Lynch, Frank: Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis. dans Cancer research 2006 (PubMed)
    Show all 2 references for ABIN2777895

  6. Human Polyclonal STAT1 Primary Antibody pour ELISA, WB - ABIN1533729 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... dans Nature 2005 (PubMed)

Plus d’anticorps contre STAT1 partenaires d’interaction

Mouse (Murine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. IFN-I can mediate ISG expression inmixed glial cell cultures (MGCs) via ISGF3 (Montrer IRF9 Anticorps)-independent signaling pathways but with reduced efficiency, with delayed and prolonged kinetics, and is more dependent on STAT1 and STAT2 (Montrer STAT2 Anticorps) than IRF9 (Montrer IRF9 Anticorps); and 2) signaling pathways not involving STAT1, STAT2 (Montrer STAT2 Anticorps), or IRF9 (Montrer IRF9 Anticorps) play a minor role only in mediating IFN-alpha (Montrer IFNA Anticorps)-stimulated genes expression in MGCs.

  2. These results demonstrate a novel mechanism by which STAT1 negatively regulates ULK1 (Montrer ULK1 Anticorps) expression and autophagy.

  3. a novel negative feedback loop mediated by STAT3 (Montrer STAT3 Anticorps)-SOCS3 (Montrer SOCS3 Anticorps), which is tightly controlled by SENP1 (Montrer SENP1 Anticorps) via de-SUMOylation of protein tyrosine phosphatase 1B (PTP1B (Montrer PTPN1 Anticorps)), in IFN-gamma (Montrer IFNG Anticorps) signaling, is reported.

  4. In a mouse model of spontaneous osteopenia caused by hyperactivation of STAT1/3 signaling downstream of gp130 (gp130 (Montrer LRPPRC Anticorps)(Y757F/Y757F)), STAT1 deletion rescued the osteopenic phenotype, indicating a beneficial effect of promoting STAT3 (Montrer STAT3 Anticorps) signaling over STAT1 downstream of gp130 (Montrer LRPPRC Anticorps) in this low bone mass condition, and this may have therapeutic value.

  5. this study shows that STAT-1 and STAT-3 (Montrer STAT3 Anticorps) interplay to regulate indoleamine 2,3-dioxygenase activity and immunosuppression in response to of IL-27 (Montrer IL27 Anticorps) in neonatal macrophages

  6. this study shows that binding motifs for the transcription factors STAT1 and IRF1 (Montrer IRF1 Anticorps) are associated with robust and IL-4 (Montrer IL4 Anticorps)-resistant responses to IFN-gamma (Montrer IFNG Anticorps) in macrophages

  7. Study showed that suppression of STAT3 (Montrer STAT3 Anticorps), STAT5 (Montrer STAT5A Anticorps), and STAT6 (Montrer STAT6 Anticorps) and overexpression of the proapoptotic factor STAT1, which provides p53 (Montrer TP53 Anticorps)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (Montrer ERBB2 Anticorps) tyrosine kinase receptor (Montrer KDR Anticorps) overexpression promotes neuronal survival through activation of STAT-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1

  8. STAT signaling plays a central role during retinal degeneration in the rd10 (Montrer PDE6B Anticorps) mouse model.

  9. Donor interleukin-22 (Montrer IL22 Anticorps) and host type I interferon (Montrer IFNA Anticorps) signaling pathway participate in intestinal graft-versus-host disease via STAT1 activation and CXCL10 (Montrer CXCL10 Anticorps).

  10. OGG1 (Montrer OGG1 Anticorps) acts as a STAT1 coactivator and has transcriptional activity in the presence of endotoxin

Human Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. the dual regulation of STAT1 by IKKalpha (Montrer CHUK Anticorps) in antiviral signaling suggests a role for IKKalpha (Montrer CHUK Anticorps) in the fine-tuning of antiviral signaling in response to non-self RNA.

  2. This study demonstrated the first coiled-coil domain mutation of STAT1 as a genetic cause of autosomal-dominant Mendelian susceptibility to mycobacterial diseases

  3. STAT1 suppression by S100A6 (Montrer S100A6 Anticorps) may represent a promising therapeutic target to facilitate reendothelialization in damaged vessels.

  4. Our data demonstrate an important connection between mRNA translation and KRAS tumorigenesis under the control of STAT1, which can determine the susceptibility of KRAS tumors to pharmacologic inhibition of mRNA translation initiation.

  5. study demonstrated that miR (Montrer MLXIP Anticorps)-9 could inhibit activation of the NLRP3 (Montrer NLRP3 Anticorps) inflammasome and attenuate atherosclerosis-related inflammation, likely through the JAK1 (Montrer JAK1 Anticorps)/STAT1 signaling pathway. Therefore, miR (Montrer MLXIP Anticorps)-9 may serve as a potential therapeutic target for atherosclerosis.

  6. the deubiquitinase USP2a translocates into the nucleus and binds to pY701-STAT1, and inhibits K48-linked ubiquitination and degradation of pY701-STAT1

  7. Demonstrate STAT1-dependent transcriptional activation of TLR8 (Montrer TLR8 Anticorps) with estrogen stimulation.

  8. STAT1 binding sites were identified on the putative miR-7 (Montrer LILRB1 Anticorps) promoter and stimulation of fibroblasts with the inflammatory cytokine, interferon-gamma (IFN-gamma (Montrer IFNG Anticorps)), significantly increased miR-7 (Montrer LILRB1 Anticorps) transcriptional activity and resulted in upregulated miR-7 (Montrer LILRB1 Anticorps) and loss of EGFR (Montrer EGFR Anticorps).

  9. These results demonstrate a novel mechanism by which STAT1 negatively regulates ULK1 (Montrer ULK1 Anticorps) expression and autophagy.

  10. In insulitic islets from living patients with recent-onset T1D, most of the overexpressed ISGs, including GBP1 (Montrer GBP1 Anticorps), TLR3 (Montrer TLR3 Anticorps), OAS1 (Montrer OAS1 Anticorps), EIF2AK2 (Montrer EIF2AK2 Anticorps), HLA-E (Montrer HLAE Anticorps), IFI6 (Montrer IFI6 Anticorps), and STAT1, showed higher expression in the islet core compared with the peri (Montrer PLIN1 Anticorps)-islet area containing the surrounding immune cells.

Pig (Porcine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon (Montrer IFNA Anticorps) response by inducing STAT1 degradation.

  2. this study shows that weaning caused severe inflammation associated with the suppression of STAT1 in the jejunum of piglets

  3. Data indicate that transmissible gastroenteritis virus (TGEV) infection activates the janus kinase signal transducer and activator of the transcription 1 (JAK (Montrer JAK3 Anticorps)-STAT1) signaling pathway.

  4. Taken together, results of these experiments describe for the first time a novel mechanism by which foot-and-mouth disease virus evolves to inhibit IFN signaling via blocking STAT1/STAT2 (Montrer STAT2 Anticorps) nuclear translocation.

  5. Nsp1beta inhibits interferon-activated (Montrer MNDA Anticorps) STAT1/STAT2 (Montrer STAT2 Anticorps) signal transduction by inducing karyopherin-alpha1 degradation.

  6. STAT1 is involved in mediating the action of ghrelin (Montrer GHRL Anticorps) on ovarian cell functions.

  7. the majority of the STAT1/STAT2 (Montrer STAT2 Anticorps)/IRF9 (Montrer IRF9 Anticorps) (IFN regulatory factor 9) heterotrimers remained in the cytoplasm of PRRSV-infected cells, which indicates that the nuclear translocation of the heterotrimers was blocked

  8. Cell-type-specific expression of STAT1 highlight the complex interplay between endometrium and conceptus for pregnancy recognition and implantation.

  9. Nitric oxide-dependent increase in caspase-8 (Montrer CASP8 Anticorps) mRNA levels is associated with phosphorylation of STAT-1 at Ser (Montrer SIGLEC1 Anticorps)-727 and STAT1 binding to the caspase-8 (Montrer CASP8 Anticorps) promoter in cultured lung endothelial cells.

  10. Activated STAT1 may be associated with or perhaps contribute to the structural and inflammatory changes in pacing-induced sustained atrial fibrillation.

Cow (Bovine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. Report interferon-tau dependent STAT1 regulation of SOCS (Montrer CISH Anticorps) genes in bovine endometrium during estrus cycle and embryo implantation.

  2. the interaction between STAT1 SNP and SNP19069 was highly significant for survival rate

  3. results show for the first time that interleukin-6 (Montrer IL6 Anticorps) (IL), in the presence of its soluble receptor (Montrer IFNAR1 Anticorps) (sIL (Montrer STIL Anticorps)-6R), induces activation of JAK1 (Montrer JAK1 Anticorps), JAK2 (Montrer JAK2 Anticorps), and STAT1/STAT3 (Montrer STAT3 Anticorps) proteins in bovine articular chondrocytes

  4. Results from this study are consistent with previous studies on the role of STAT1 in regulating the transcription of genes involved in milk protein (Montrer CSN2 Anticorps) synthesis and fat metabolism.

  5. Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 and, to a lesser extent, STAT2 (Montrer STAT2 Anticorps).

STAT1 profil antigène

Antigen Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT1

  • signal transducer and activator of transcription 1, 91kDa (STAT1) anticorps
  • RIKEN cDNA 2200002D01 gene (2200002D01Rik) anticorps
  • signal transducer and activator of transcription 1 (Stat1) anticorps
  • signal transducer and activator of transcription 1, 91kDa (stat1) anticorps
  • signal transducer and activator of transcription 4 (stat4) anticorps
  • 2010005J02Rik anticorps
  • AA408197 anticorps
  • CANDF7 anticorps
  • DD6G4-4 anticorps
  • dZ182H3.3 anticorps
  • H2RSP anticorps
  • IMUP anticorps
  • IMUP-1 anticorps
  • IMUP-2 anticorps
  • ISGF-3 anticorps
  • si:by51f19.1 anticorps
  • si:by134g18.2 anticorps
  • si:dz73o4.2 anticorps
  • si:dz182h3.3 anticorps
  • si:dz199m19.1 anticorps
  • STAT anticorps
  • STAT1 anticorps
  • STAT4 anticorps
  • STAT91 anticorps
  • XStat1 anticorps

Protein level used designations for STAT1

signal transducer and activator of transcription 1-alpha/beta , HAI-2 related small protein , signal transducer and activator of transcription-1 , transcription factor ISGF-3 components p91/p84 , signal transducer and activator of transcription 4 , signal transducer and activator of transcription 1 , transcription factor ISGF-3 , activator of transcription , signal transduction

100307049 Ovis aries
72275 Mus musculus
20846 Mus musculus
25124 Rattus norvegicus
6772 Homo sapiens
424044 Gallus gallus
488449 Canis lupus familiaris
396655 Sus scrofa
510814 Bos taurus
398324 Xenopus laevis
100343893 Oryctolagus cuniculus
368519 Danio rerio
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