Aperçu des produits pour anti-STAT1 (STAT1) Anticorps

Full name:
anti-Signal Transducer and Activator of Transcription 1, 91kDa Anticorps (STAT1)
Chez www.anticorps-enligne.fr sont 635 Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) Anticorps de 38 de différents fournisseurs disponibles. De plus, nous expédions STAT1 Kits (46) et STAT1 Protéines (21) et beaucoup plus de produits pour cette protéine. Un total de 747 STAT1 produits sont actuellement listés.
Synonymes:
2010005J02Rik, AA408197, CANDF7, DD6G4-4, dZ182H3.3, H2RSP, IMUP, IMUP-1, IMUP-2, ISGF-3, si:by51f19.1, si:by134g18.2, si:dz73o4.2, si:dz182h3.3, si:dz199m19.1, STAT, STAT1, STAT4, STAT91, XStat1
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STAT1 72275  
STAT1 25124  
STAT1 6772 P42224

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anti-STAT1 Anticorps mieux référencés

  1. Human Polyclonal STAT1 Primary Antibody pour EIA, IHC (p) - ABIN358231 : Garcin, Marq, Iseni, Martin, Kolakofsky: A short peptide at the amino terminus of the Sendai virus C protein acts as an independent element that induces STAT1 instability. dans Journal of virology 2004 (PubMed)
    Show all 5 references for 358231

  2. Human Polyclonal STAT1 Primary Antibody pour IF (p), IHC (p) - ABIN674889 : Wang, Wang, Song, Chu, Qu: Deficiency of interferon-gamma or its receptor promotes colorectal cancer development. dans Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2015 (PubMed)
    Show all 3 references for 674889

  3. Human Monoclonal STAT1 Primary Antibody pour IHC (p), IP - ABIN269146 : Kovarik, Boudny, Kocak, Lauerova, Fait, Vagundova: Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. dans International journal of molecular medicine 2003 (PubMed)
    Show all 2 references for 269146

  4. Cow (Bovine) Polyclonal STAT1 Primary Antibody pour IHC, WB - ABIN2780843 : Battle, Lynch, Frank: Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis. dans Cancer research 2006 (PubMed)
    Show all 2 references for 2780843

  5. Human Polyclonal STAT1 Primary Antibody pour IF, IHC - ABIN1533008 : Durbin, Hackenmiller, Simon, Levy: Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. dans Cell 1996 (PubMed)
    Show all 2 references for 1533008

  6. Human Polyclonal STAT1 Primary Antibody pour ELISA, WB - ABIN1533729 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... dans Nature 2005 (PubMed)

Plus d’anticorps contre STAT1 partenaires d’interaction

Mouse (Murine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. In cultured macrophages, LPS (Montrer TLR4 Anticorps)-induced expression of monocyte chemoattractant protein (MCP)-1 (Montrer CPT1B Anticorps) was suppressed by NaN3 through inhibition of STAT1 and IkappaBzeta (Montrer NFKBIZ Anticorps) activities.

  2. Quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting were used to detect the mRNA and protein expressions of p-p38MAPK (Montrer MAPK14 Anticorps), AAT (Montrer SERPINA1A Anticorps), signal transducer and activator of transcription 1 (STAT1) and activating transcription factor2 (ATF2 (Montrer ATF2 Anticorps))

  3. This secreted effector, toxoplasma inhibitor of STAT1-dependent transcription (TgIST), translocates to the host cell nucleus, where it recruits mouse Mi-2 (Montrer CHD4 Anticorps)/NuRD to STAT1-dependent promoters, resulting in altered chromatin and blocked transcription.

  4. Microbiome depletion as a result of broad-spectrum antibiotic treatment disrupts basal Stat1 signaling and alters T-cell homeostasis, leading to impaired progenitor maintenance and granulocyte maturation.

  5. We revealed that in mouse mesenchymal stem cells IFN-gamma-induced (Montrer SAMHD1 Anticorps) immunoregulation is mediated by early phosphorylation of signal transducer and activator of transcription (STAT) 1 and STAT3 (Montrer STAT3 Anticorps), which is significantly enhanced by an extracellular signal-regulated kinase 1/2 (Montrer MAPK3 Anticorps)-dependent mTOR (Montrer FRAP1 Anticorps) inhibition, thereby promoting pSTAT1 nuclear translocation.

  6. these results define a differential regulation of TLR-mediated activation and differentiation of MZ B cells by STAT1 and reveal a STAT1-dependent, but IFN-independent, antibody response during infection and inflammation.

  7. B cell-intrinsic IFN-gamma (Montrer IFNG Anticorps) receptor (IFN-gammaR (Montrer IFNGR1 Anticorps)) and STAT1 signaling are required for Spontaneously developed germinal centers and follicular T helper cell (Tfh cell) development.

  8. Inhibitor-sensitive tyrosine kinase (Montrer TYRO3 Anticorps) controls the population heterogeneity of basal STAT1 activity in Ube1l (Montrer UBA7 Anticorps) deficient fibroblasts.

  9. The studies presented here reveal that the ability of IFN-gamma (Montrer IFNG Anticorps) to inhibit parasite replication in astrocytes in vitro is dependent on signal transducer and activator of transcription 1 (STAT1) and that mice that specifically lack STAT1 in astrocytes are unable to limit parasite replication in the central nervous system (CNS).

  10. We found that STAT-1(-/-) MRL lpr (Montrer FAS Anticorps) mice, but not IRF-9 (Montrer IRF9 Anticorps)(-/-) or IFNAR-2 (Montrer IFNAR2 Anticorps)(-/-) mice, developed interstitial nephritis characterized by infiltration with RORgammat-positive lymphocytes, macrophages, and eosinophils. Despite pronounced interstitial kidney disease and abnormal kidney function, STAT-1(-/-) mice had decreased proteinuria, glomerulonephritis, and autoantibody production.

Human Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. MFSD2B, CCL20 (Montrer CCL20 Anticorps) and STAT1, or STARD7 (Montrer STARD7 Anticorps) and ZNF512 (Montrer ZNF512 Anticorps) genes may be risk or protect factors in prognosis of ADC (Montrer ADC Anticorps); HTR2B (Montrer HTR2B Anticorps), DPP4 (Montrer DPP4 Anticorps), and TGFBRAP1 (Montrer TGFBRAP1 Anticorps) genes may be risk factors in prognosis of SQC (Montrer QPCT Anticorps).

  2. In cultured macrophages, LPS (Montrer IRF6 Anticorps)-induced expression of monocyte chemoattractant protein (MCP)-1 (Montrer CCL2 Anticorps) was suppressed by NaN3 through inhibition of STAT1 and IkappaBzeta (Montrer NFKBIZ Anticorps) activities.

  3. Functional analysis of NK cells shows a significant impairment of cytolytic and degranulation activities in chronic mucocutaneous candidiasis patients with STAT1 GOF mutations

  4. Mechanistic investigations reveal that AJUBA (Montrer AJUBA Anticorps) specifically binds the FERM domain of JAK1 (Montrer JAK1 Anticorps) to dissociate JAK1 (Montrer JAK1 Anticorps) from the IFNgamma recepter, resulting in an inhibition of STAT1 phosporylation and concomitantly its nuclear translocation. Clinically, the level of AJUBA (Montrer AJUBA Anticorps) in CRC (Montrer CALR Anticorps) specimens is negatively correlated with the levels of IFIT2 (Montrer IFIT2 Anticorps) and pSTAT1

  5. Low STAT1 expression is associated with Pancreatic cancer.

  6. STAT1 and IRF1 (Montrer IRF1 Anticorps) collaborate to induce interferon-gamma (Montrer IFNG Anticorps) stimulated genes (ISGs), but the extent to which they act alone or together is unclear.This study provides strong evidence for widespread cooperation between STAT1 and IRF1 (Montrer IRF1 Anticorps) at ISGs, and suggests that in silico predictions reliably predict the effect of nucleotide variants on binding in vivo.

  7. IFITM1 (Montrer IFITM1 Anticorps) suppression blocks proliferation and invasion of aromatase (Montrer CYP19A1 Anticorps) inhibitor-resistant breast cancer in vivo by JAK (Montrer JAK3 Anticorps)/STAT1-mediated induction of p21 (Montrer CDKN1A Anticorps).

  8. This study reports a new role for SETD2 (Montrer SETD2 Anticorps) in promoting IFNalpha-induced antiviral immune response by directly methylating STAT1 on lysine 525 and catalyzing H3K36me3 on the promoters of some IFN-stimulated genes (ISGs such as ISG15 (Montrer ISG15 Anticorps)) to activate gene transcription. Thus, SETD2 (Montrer SETD2 Anticorps) enhances host antiviral immunity by strengthening IFNalpha signaling both post-translationally and epigenetically.

  9. STAT1 gain-of-function mutations underlie Autosomal dominant chronic mucocutaneous candidiasis, as well as an unexpectedly wide range of other clinical features, including not only a variety of infectious and autoimmune diseases, but also cerebral aneurysms and carcinomas that confer a poor prognosis.

  10. Six different heterozygous mutations in STAT1 were detected in the seven patients (Patients 3 and 4 shared identical mutations). Three of these mutations were recurrent variants (p.R274Q, p.K388E and p.P329L), whereas the other three (p.N357D, p.M202T, and p.T437I), involving both the coiled coil domain (CCD (Montrer RUNX2 Anticorps)) and DNA binding domain (DBD), have not been reported previously.

Pig (Porcine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon (Montrer IFNA Anticorps) response by inducing STAT1 degradation.

  2. this study shows that weaning caused severe inflammation associated with the suppression of STAT1 in the jejunum of piglets

  3. Data indicate that transmissible gastroenteritis virus (TGEV) infection activates the janus kinase signal transducer and activator of the transcription 1 (JAK (Montrer JAK3 Anticorps)-STAT1) signaling pathway.

  4. Taken together, results of these experiments describe for the first time a novel mechanism by which foot-and-mouth disease virus evolves to inhibit IFN signaling via blocking STAT1/STAT2 (Montrer STAT2 Anticorps) nuclear translocation.

  5. Nsp1beta inhibits interferon-activated (Montrer MNDA Anticorps) STAT1/STAT2 (Montrer STAT2 Anticorps) signal transduction by inducing karyopherin-alpha1 degradation.

  6. STAT1 is involved in mediating the action of ghrelin (Montrer GHRL Anticorps) on ovarian cell functions.

  7. the majority of the STAT1/STAT2 (Montrer STAT2 Anticorps)/IRF9 (Montrer IRF9 Anticorps) (IFN regulatory factor 9) heterotrimers remained in the cytoplasm of PRRSV-infected cells, which indicates that the nuclear translocation of the heterotrimers was blocked

  8. Cell-type-specific expression of STAT1 highlight the complex interplay between endometrium and conceptus for pregnancy recognition and implantation.

  9. Nitric oxide-dependent increase in caspase-8 (Montrer CASP8 Anticorps) mRNA levels is associated with phosphorylation of STAT-1 at Ser (Montrer SIGLEC1 Anticorps)-727 and STAT1 binding to the caspase-8 (Montrer CASP8 Anticorps) promoter in cultured lung endothelial cells.

  10. Activated STAT1 may be associated with or perhaps contribute to the structural and inflammatory changes in pacing-induced sustained atrial fibrillation.

Cow (Bovine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. Report interferon-tau dependent STAT1 regulation of SOCS (Montrer CISH Anticorps) genes in bovine endometrium during estrus cycle and embryo implantation.

  2. the interaction between STAT1 SNP and SNP19069 was highly significant for survival rate

  3. results show for the first time that interleukin-6 (Montrer IL6 Anticorps) (IL), in the presence of its soluble receptor (Montrer IFNAR1 Anticorps) (sIL (Montrer STIL Anticorps)-6R), induces activation of JAK1 (Montrer JAK1 Anticorps), JAK2 (Montrer JAK2 Anticorps), and STAT1/STAT3 (Montrer STAT3 Anticorps) proteins in bovine articular chondrocytes

  4. Results from this study are consistent with previous studies on the role of STAT1 in regulating the transcription of genes involved in milk protein (Montrer CSN2 Anticorps) synthesis and fat metabolism.

  5. Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 and, to a lesser extent, STAT2 (Montrer STAT2 Anticorps).

STAT1 profil antigène

Antigen Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT1

  • signal transducer and activator of transcription 1, 91kDa (STAT1) anticorps
  • RIKEN cDNA 2200002D01 gene (2200002D01Rik) anticorps
  • signal transducer and activator of transcription 1 (Stat1) anticorps
  • signal transducer and activator of transcription 1, 91kDa (stat1) anticorps
  • signal transducer and activator of transcription 4 (stat4) anticorps
  • 2010005J02Rik anticorps
  • AA408197 anticorps
  • CANDF7 anticorps
  • DD6G4-4 anticorps
  • dZ182H3.3 anticorps
  • H2RSP anticorps
  • IMUP anticorps
  • IMUP-1 anticorps
  • IMUP-2 anticorps
  • ISGF-3 anticorps
  • si:by51f19.1 anticorps
  • si:by134g18.2 anticorps
  • si:dz73o4.2 anticorps
  • si:dz182h3.3 anticorps
  • si:dz199m19.1 anticorps
  • STAT anticorps
  • STAT1 anticorps
  • STAT4 anticorps
  • STAT91 anticorps
  • XStat1 anticorps

Protein level used designations for STAT1

signal transducer and activator of transcription 1-alpha/beta , HAI-2 related small protein , signal transducer and activator of transcription-1 , transcription factor ISGF-3 components p91/p84 , signal transducer and activator of transcription 4 , signal transducer and activator of transcription 1 , transcription factor ISGF-3 , activator of transcription , signal transduction

GENE ID SPECIES
100307049 Ovis aries
72275 Mus musculus
20846 Mus musculus
25124 Rattus norvegicus
6772 Homo sapiens
424044 Gallus gallus
488449 Canis lupus familiaris
396655 Sus scrofa
510814 Bos taurus
398324 Xenopus laevis
100343893 Oryctolagus cuniculus
368519 Danio rerio
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