Aperçu des produits pour anti-Dystrobrevin Binding Protein 1 (DTNBP1) Anticorps

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anti-Dystrobrevin Binding Protein 1 Anticorps (DTNBP1)
Chez www.anticorps-enligne.fr sont 119 Dystrobrevin Binding Protein 1 (DTNBP1) Anticorps de 16 de différents fournisseurs disponibles. De plus, nous expédions Dystrobrevin Binding Protein 1 Protéines (17) et Dystrobrevin Binding Protein 1 Kits (9) et beaucoup plus de produits pour cette protéine. Un total de 152 Dystrobrevin Binding Protein 1 produits sont actuellement listés.
Synonymes:
5430437B18Rik, AW048963, Bloc1s8, CG6856, DBND, Ddysb, Dmel\\CG6856, DTNBP1, dysbindin, HPS7, MGC83903, MGC85477, My031, sdy, zgc:56462

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anti-Dystrobrevin Binding Protein 1 Anticorps mieux référencés

  1. Human Polyclonal DTNBP1 Primary Antibody pour EIA, WB - ABIN952010 : Haukvik, Saetre, McNeil, Bjerkan, Andreassen, Werge, Jönsson, Agartz: An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes. dans Progress in neuro-psychopharmacology & biological psychiatry 2010 (PubMed)
    Show all 3 references for 952010

  2. Human Polyclonal DTNBP1 Primary Antibody pour EIA, IHC (p) - ABIN357845 : Benson, Newey, Martin-Rendon, Hawkes, Blake: Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain. dans The Journal of biological chemistry 2001 (PubMed)
    Show all 3 references for 357845

  3. Human Polyclonal DTNBP1 Primary Antibody pour IHC, IHC (p) - ABIN4306530 : Gokhale, Mullin, Zlatic, Easley, Merritt, Raj, Larimore, Gordon, Peden, Sanyal, Faundez: The N-ethylmaleimide-sensitive factor and dysbindin interact to modulate synaptic plasticity. dans The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 (PubMed)
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Plus d’anticorps contre Dystrobrevin Binding Protein 1 partenaires d’interaction

Fruit Fly (Drosophila melanogaster) Dystrobrevin Binding Protein 1 (DTNBP1) interaction partners

  1. Results indicate that perturbations downstream of DTNBP1, confer susceptibility to copper, a metal that in excess (Montrer RCC1 Anticorps) is a neurotoxin and whose depletion constitutes a micronutrient deficiency.

  2. Loss-of-function alleles of dysbindin or Blos1 (Montrer BLOC1S1 Anticorps) impaired neurotransmitter release and synaptic function and plasticity.

  3. optimal binding ratio between Dysb and Ebony might contribute to such non-linear effects. Thus, Ddysb-dependent regulation of Ebony could be one of the mechanisms that mediate dopamine signal

  4. study found that dysbindin (CG6856) is required presynaptically for the retrograde, homeostatic modulation of neurotransmission, and functions in a dose-dependent manner downstream or independently of calcium influx

Human Dystrobrevin Binding Protein 1 (DTNBP1) interaction partners

  1. Study analyzed human-specific dysbindin-1B expression in multiple brain areas in mouse models and showed that dysbindin-1B exerts a dominant-negative effect on the BLOC-1 (Montrer BLOC1S1 Anticorps) complex; this effect may lead to cognitive impairment.

  2. This study demonstrated that BDNF (Montrer BDNF Anticorps) and dysbindin-1 linked to risk for schizophrenia function together to regulate interneuron development and cortical network activity.

  3. This is the first study to suggest that known and newly described polymorphisms in COMT (Montrer COMT Anticorps), BDNF (Montrer BDNF Anticorps), and DTNBP1, genes associated with executive and memory functions in healthy individuals and other clinical populations may modulate cognitive outcome in patients with brain tumors

  4. Data suggest that, in cardiomyocytes, TRIM32 attenuates activation of SRF signaling and hypertrophy due to dysbindin; TRIM24 promotes these effects. TRIM32 promotes dysbindin degradation; TRIM24 protects dysbindin from degradation. (TRIM = tripartite motif-containing protein; SRF = serum response factor)

  5. Authors report the examination of DNA methylation status of DTNBP1 promoter region, one of the most credible candidate genes affected in SCZ.

  6. DTNBP1 is likely to play a role in development of auditory related, visual and olfactory hallucinations

  7. dysbindin-1A protein levels are highly regulated in the nucleus and that dysbindin-1A regulates transcription factor NF-kappa B (Montrer NFKB1 Anticorps) activity to promote the expression of MMP-9 (Montrer MMP9 Anticorps) and TNF-alpha (Montrer TNF Anticorps)

  8. Study demonstrated that dysbindin-1B, rather than dysbindin-1A and dysbindin-1C, has the ability to aggregate

  9. The present findings intransgenic mice expressing human DTNBP1 support the role of dysbindin-1 in psychiatric disorders.

  10. Findings add further evidence suggesting an association between dysbindin gene variability and cognitive abnormalities in schizophrenia.

Mouse (Murine) Dystrobrevin Binding Protein 1 (DTNBP1) interaction partners

  1. loss of DTNBP1 in pyramidal neurons diminished activity-dependent secretion of brain-derived neurotrophic factor (BDNF (Montrer BDNF Anticorps)).

  2. Dysbindin-1 modulates thus D2 and D3 receptor (Montrer DRD3 Anticorps) signaling, supporting a link to schizophrenia

  3. Results indicate that perturbations downstream of DTNBP1, confer susceptibility to copper, a metal that in excess (Montrer RCC1 Anticorps) is a neurotoxin and whose depletion constitutes a micronutrient deficiency.

  4. Results suggest that Dtnbp1 deficiency may lead to increased vulnerability to schizophrenia under environmental conditions where circadian rhythms are altered

  5. Snapin-dysbindin interaction regulates synaptic vesicle positional priming through BLOC-1/AP-3-dependent sorting.

  6. Dysbindin has three isoforms associating with different complexes in the P2 fraction of mouse brain.

  7. Dysbindin-1C deficiency causes impaired autophagy, which is likely implicated in the pathogenesis of schizophrenia.

  8. The neurite outgrowth defect induced by knockdown of DISC1 (Montrer DISC1 Anticorps) was partially reversed by coexpression of dysbindin.

  9. dysbindin-1C, rather than dysbindin-1A, regulates adult hippocampal neurogenesis in a non-cell autonomous manner

  10. loss of function mutations in the genes encoding dysbindin and its interacting BLOC-1 (Montrer PLDN Anticorps) subunits

Dystrobrevin Binding Protein 1 (DTNBP1) profil antigène

Antigen Summary

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with Dystrobrevin Binding Protein 1 (DTNBP1)

  • dystrobrevin binding protein 1 (DTNBP1) anticorps
  • dysbindin (dysb) anticorps
  • Dysbindin (dtbp1) anticorps
  • dystrobrevin binding protein 1a (dtnbp1a) anticorps
  • dystrobrevin binding protein 1 (dtnbp1) anticorps
  • dystrobrevin binding protein 1 (Dtnbp1) anticorps
  • 5430437B18Rik anticorps
  • AW048963 anticorps
  • Bloc1s8 anticorps
  • CG6856 anticorps
  • DBND anticorps
  • Ddysb anticorps
  • Dmel\\CG6856 anticorps
  • DTNBP1 anticorps
  • dysbindin anticorps
  • HPS7 anticorps
  • MGC83903 anticorps
  • MGC85477 anticorps
  • My031 anticorps
  • sdy anticorps
  • zgc:56462 anticorps

Protein level used designations for DTNBP1

dysbindin , CG6856-PA , CG6856-PB , dysb-PA , dysb-PB , Dysbindin , BLOC-1 subunit 8-A , biogenesis of lysosome-related organelles complex 1 subunit 8-A , dysbindin-A , dystrobrevin binding protein 1 , dystrobrevin-binding protein 1-A , BLOC-1 subunit 8 , Hermansky-Pudlak syndrome 7 protein , biogenesis of lysosomal organelles complex-1, subunit 8 , biogenesis of lysosome-related organelles complex 1 subunit 8 , dysbindin-1 , HPS7 protein homolog , dystrobrevin-binding protein 1 , hermansky-Pudlak syndrome 7 protein homolog , sandy , distrobrevin binding protein 1

GENE ID SPECIES
100145862 Ovis aries
40052 Drosophila melanogaster
100195576 Salmo salar
394109 Danio rerio
446421 Xenopus laevis
447615 Xenopus laevis
747324 Pan troglodytes
100216117 Xenopus (Silurana) tropicalis
84062 Homo sapiens
94245 Mus musculus
420840 Gallus gallus
100049697 Sus scrofa
506612 Bos taurus
641528 Rattus norvegicus
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