anti-Humain C1S anticorps pour Enzyme Immunoassay

Recommended C1S Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Complement Component 1, S Subcomponent (C1S) Anticorps
  • C1S
  • r-gsp
  • AA959438
  • AI255193
  • AI327365
  • C1sa
  • complement component 1, s subcomponent
  • C1S
  • c1s
  • LOC100222051
  • C1s
Reactivité
Humain
80
21
21
3
1
Hôte
Souris
46
30
4
Clonalité
Monoclonal
Conjugué
Cet anticorp C1S est non-conjugé
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Functional Studies (Func), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
51
26
24
13
13
11
7
5
3
3
2
2
2
1
1
1
1
1
1
1
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N° du produit ABIN1105612
484,00 €
Plus frais de livraison 40,00 € et TVA
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN614875 EIA IHC (p) Goat IgG Connectez-vous pour afficher Polyclonal
1 ABIN1105613 Func EIA IHC (fro) IHC (p) IP WB Mouse IgG2a activated Connectez-vous pour afficher M241 2

anti-C1S anticorps pour Enzyme Immunoassay mieux référencés

anti-C1S Anticorps

Application / Reactivité Humain
Blocking Peptide (BP) 1 Anticorps
Cell Culture (CC) 1 Anticorps
ELISA 26 Anticorps
ELISA (Detection) 1 Anticorps
Enzyme Immunoassay (EIA) 3 Anticorps
Flow Cytometry (FACS) 11 Anticorps
Functional Studies (Func) 2 Anticorps
Immunoassay (IA) 2 Anticorps
Immunocytochemistry (ICC) 3 Anticorps
Immunodiffusion (ID) 1 Anticorps
Immunofluorescence (IF) 7 Anticorps
Immunofluorescence (fixed cells) (IF/ICC) 2 Anticorps
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Anticorps
Immunohistochemistry (IHC) 24 Anticorps
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Anticorps
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Anticorps
Immunoprecipitation (IP) 6 Anticorps
Inhibition Assay (InhA) 1 Anticorps
Neutralization (Neut) 1 Anticorps

General

Antigène Complement Component 1, S Subcomponent (C1S) Anticorps
Reactivité Humain
(80), (21), (21), (3), (1)
Hôte Souris
(46), (30), (4)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp C1S est non-conjugé
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Functional Studies (Func), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(51), (26), (24), (13), (13), (11), (7), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 références disponible
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Détail du produit anti-C1S anticorps

Détail du antigène C1S Information d'application Stockage ProductDetails: References for anti-C1S antibody (ABIN1105612) Images
Specificité Monoclonal antibody M81 reacts with an epitope on human C protein activated C1s, a subcomponent of the first component of C (C1). The epitope recognised by the antibody M81 is domain IV and/or V of the gamma-domain of activated C1s. It blocks C4 activation and C4 binding to activated C1s. The antibody reacts around the binding site of C1s and reacts with both active and inactive C1s.
Réactivité croisée (Details) Species reactivity (tested):Human
Purification Protein G
Clone M81
Isotype IgG1

Détail du antigène C1S

Détail du produit anti-C1S anticorps Information d'application Stockage ProductDetails: References for anti-C1S antibody (ABIN1105612) Images Haut de la page
Antigène
Autre désignation C1s (C1S Antibody Extrait)
Sujet Activated C1s is a glycosylated single-polypeptide zymogen, MW 85 kD. Activation of the proenzyme C1s occurs through cleavage by the active form of C1r. The activated protease, activated C1s, consists of a disulfide-linked H chain and a L chain. Activated C1s is a serine protease and its catalytic site is located in the L chain. Activation of the classical C pathway is triggered by activated C1s which cleaves C4 and C2 to form the C3 convertase, C4bC2a.Synonyms: C1 esterase, Complement 1s, Complement C1s, Complement C1s subcomponent, Complement component 1 subcomponent s
ID gène 716
NCBI Accession NP_001725
UniProt P09871
Domaine de recherche Immunology, Innate Immunity, Complement Factors
Pathways Système du Complément

Information d'application

Détail du produit anti-C1S anticorps Détail du antigène C1S Stockage ProductDetails: References for anti-C1S antibody (ABIN1105612) Images Haut de la page
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Stockage

Détail du produit anti-C1S anticorps Détail du antigène C1S Information d'application ProductDetails: References for anti-C1S antibody (ABIN1105612) Images Haut de la page
Concentration 0.1 mg/mL
Buffer PBS, 0.1 % bovine serum albumin
Stock 4 °C
Stockage commentaire Store at 2 - 8 °C.

ProductDetails: References for anti-C1S antibody (ABIN1105612)

Détail du produit anti-C1S anticorps Détail du antigène C1S Information d'application Stockage Images Haut de la page
Background publications

Nakagawa, Sakiyama, Tsuchida, Yamaguchi, Toyoguchi, Masuda, Moriya: "Complement C1s activation in degenerating articular cartilage of rheumatoid arthritis patients: immunohistochemical studies with an active form specific antibody." dans: Annals of the rheumatic diseases, Vol. 58, Issue 3, pp. 175-81, 1999

Matsumoto, Nagaki, Kitamura, Kuramitsu, Nagasawa, Seya: "Probing the C4-binding site on C1s with monoclonal antibodies. Evidence for a C4/C4b-binding site on the gamma-domain." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 8, pp. 2743-50, 1989