Aperçu des produits pour anti-Prothrombin (F2) Anticorps

Full name:
anti-Coagulation Factor II (thrombin) Anticorps (F2)
Chez www.anticorps-enligne.fr sont 228 Coagulation Factor II (thrombin) (F2) Anticorps de 25 de différents fournisseurs disponibles. De plus, nous expédions Prothrombin Kits (123) et Prothrombin Protéines (50) et beaucoup plus de produits pour cette protéine. Un total de 409 Prothrombin produits sont actuellement listés.
Synonymes:
AA959438, AI255193, AI327365, C1sa, Cf-2, Cf2, F2, FII, HTRA, HTRA1, prothrombin, PT, RPRGL2, THPH1, thrombin, wu:fb57c10, wu:fd42e09, wu:fd59d01, zgc:66319

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anti-Prothrombin Anticorps mieux référencés

  1. Human Monoclonal Prothrombin Primary Antibody pour WB - ABIN394859 : Ikejiri, Wada, Sakamoto, Ito, Nishioka, Nakatani, Tsuji, Yamada, Nakamura, Ito, Nobori: The association of protein S Tokushima-K196E with a risk of deep vein thrombosis. dans International journal of hematology 2010 (PubMed)
    Show all 5 references for 394859

  2. Human Monoclonal Prothrombin Primary Antibody pour EIA, WB - ABIN954322 : Kazama, Pastuszyn, Wildgoose, Hamamoto, Kisiel: Isolation and characterization of proteolytic fragments of human factor VIIa which inhibit the tissue factor-enhanced amidolytic activity of factor VIIa. dans The Journal of biological chemistry 1993 (PubMed)
    Show all 3 references for 954322

  3. Human Monoclonal Prothrombin Primary Antibody pour EIA, WB - ABIN954323 : Bharadwaj, Iino, Kontoyianni, Smith, Foster, Kisiel: Factor VII central. A novel mutation in the catalytic domain that reduces tissue factor binding, impairs activation by factor Xa, and abolishes amidolytic and coagulant activity. dans The Journal of biological chemistry 1997 (PubMed)
    Show all 3 references for 954323

  4. Cow (Bovine) Polyclonal Prothrombin Primary Antibody pour IHC, WB - ABIN2776976 : Rossi, Za, Ciminello, Leone, De Stefano: The risk of symptomatic pulmonary embolism due to proximal deep venous thrombosis differs in patients with different types of inherited thrombophilia. dans Thrombosis and haemostasis 2008 (PubMed)

  5. Human Polyclonal Prothrombin Primary Antibody pour IHC, ELISA - ABIN1583288 : Fritze, Zhang, Li, Chai, Mulholland: Thrombin mediates vagal apoptosis and dysfunction in inflammatory bowel disease. dans Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2014 (PubMed)

Plus d’anticorps contre Prothrombin partenaires d’interaction

Zebrafish Coagulation Factor II (thrombin) (F2) interaction partners

  1. Prothrombin morpholino-injected zebrafish embryos yielded an early phenotype exhibiting severe abnormalities that later showed occasional bleeding

Rhesus Monkey Coagulation Factor II (thrombin) (F2) interaction partners

  1. The great similarity of prothrombin among rhesus, human, and porcine confirm the great value of the pig-to-rhesus xenotransplantation model.

Mouse (Murine) Coagulation Factor II (thrombin) (F2) interaction partners

  1. These findings imply that a thrombin-pericyte interaction in the brain could be a significant mechanism responsible for blood-brain barrier dysfunction under obesity-associated diabetic conditions and thus could represent a therapeutic target for central nervous system complications of diabetes.

  2. mutations were introduced into the endogenous fII gene, resulting in expression of prothrombin carrying 3 amino acid substitutions (R157A, R268A, and K281A) to limit activation events to yield only fIIa(Meizothrombin) Homozygous fII(MZ) mice are viable, express fII levels comparable with fII(Wild type) mice, and have reproductive success.

  3. Biglycan (Montrer BGN Anticorps) plays a protective role during the progression of atherosclerosis in ApoE (Montrer APOE Anticorps)-deficient mice by inhibiting thrombin generation.

  4. allosteric inhibitor SbO4L targets the glycoprotein Ibalpha (Montrer GP1BA Anticorps)-binding and heparin-binding site of thrombin

  5. thrombin/PAR-1 (Montrer MARK2 Anticorps) interaction regulated MCP-1 (Montrer CPT1B Anticorps), TF, MCSF (Montrer CSF1 Anticorps) and IL-6 (Montrer IL6 Anticorps) production.

  6. Observations illustrate the role of thrombin as a pleiotropic atherogenic molecule under conditions of hypercholesterolemia and suggest the utility of its inhibition with locally acting antithrombin (Montrer SERPINC1 Anticorps) nanoparticle therapeutics.

  7. Thrombin-PAR1 (Montrer F2R Anticorps) signaling, via nitric oxide and EPCR (Montrer PROCR Anticorps), promotes hematopoietic stem cell (HSC (Montrer FUT1 Anticorps)) mobilization.

  8. Primary tumor growth by colon cancer cells was reduced by reduction of circulating prothrombin. There were lower mitotic indices and invasiveness. This growth relied upon 2 targets of thrombin-mediated proteolysis, protease: PAR-1 and fibrinogen.

  9. Thrombin promotes sustained signaling and inflammatory gene expression through the CDC25 and Ras-associating domains of phospholipase C epsilon.

  10. thrombin/PAR1 (Montrer F2R Anticorps) pathway as a novel target for developing therapeutic strategies to restore synaptic function in the acute phase of ischemic stroke.

Human Coagulation Factor II (thrombin) (F2) interaction partners

  1. An in silico and in vitro approach to elucidate the impact of residues flanking the cleavage scissile bonds of FVIII (Montrer F8 Anticorps) by thrombin has been presented.

  2. These studies clarify the role of PKCdelta (Montrer PKCd Anticorps) in endothelial cell cytoskeleton regulation.

  3. Findings indicate functional effects of thrombin allostery and suggest that individual active site-directed thrombin inhibitors uniquely modulate exosite function.

  4. Acute Coronary Syndrome patients had an enhanced prothrombotic profile, demonstrated by an increased thrombin generation potential, factor XIa and D-dimer levels.

  5. we have found a novel homozygous mutation (p.Tyr510Asp) in the exon 13 of prothrombin gene in a Chinese proband. The mutation is responsible for the prothrombin deficiency reported here. Identification of the prothrombin deficiency in this family allowed mutation-specific prenatal screening.

  6. Individuals suffering from relapsing-remitting and secondary progressive multiple sclerosis had significantly higher prothrombin and factor X levels than healthy donors, whereas levels were unchanged in primary progressive MS and neuromyelitis optica patients.

  7. Prothrombin loading of vascular smooth muscle cell-derived exosomes regulates coagulation and calcification.

  8. Case Reports: prothrombin Padua 2 induces antithrombin (Montrer SERPINC1 Anticorps) resistance and is associated with an increased risk of venous thromboembolism. Codon 596 (CGG) of prothrombin is a hot spot for mutations, which constitute a new and relatively frequent cause of inherited thrombophilia.

  9. Thrombin cleavage sites were mapped to the Duffy binding-like delta1 (DBLdelta1) domain and interdomains 1 and 2 in the PfEMP1 of the parasite line IT4var19.

  10. Furthermore, thrombin treatment of the inflammatory matrix leads to dissolution of HC-HA cable structures and abolishes leukocyte adhesion. These data establish a novel mechanism whereby thrombin cleavage of HC1 regulates the adhesive properties of an inflammatory HA matrix.

Cow (Bovine) Coagulation Factor II (thrombin) (F2) interaction partners

  1. the weaker rapid interaction between prothrombin and membranes is the most important in vivo when considering the activation of prothrombin at the cell surface.

  2. novel pyranosic sulfated (Montrer SULF1 Anticorps) arabinan Ab1 exerts its anticoagulant activity on thrombin by a mechanism different from those found previously for other sulfated (Montrer SULF1 Anticorps) polysaccharides and glycosaminoglycans

  3. Exogenous delivery of thrombin enhances microvascular collateral development in response to ischemic insult, and accelerates tissue reperfusion.

  4. the signaling pathways of MAPK (Montrer MAPK1 Anticorps), MSK1 (Montrer RPS6KA5 Anticorps), and NF-kappaB (Montrer NFKB1 Anticorps) play important roles in thrombin-induced iNOS (Montrer NOS2 Anticorps) expression in alveolar macrophages

  5. High glucose enhances smooth muscle cell responsiveness to thrombin through transcriptional upregulation of PAR-4, mediated via PKC and NFkappaB.

  6. Thrombin induces a sustained contraction in the normal pulmonary artery, by activating PAR(1 (Montrer F2R Anticorps)) and thereby increasing the sensitivity of the myofilament to Ca(2 (Montrer CA2 Anticorps)+).

  7. kinetic and structural analysis of interactions between thrombin and the Factor XIII (Montrer UGDH Anticorps) activation peptide

  8. analysis of staphylocoagulase-mediated bovine prothrombin activation

  9. thrombin and factor Xa (Montrer F10 Anticorps) diffusion along the heparin molecule explains the effects of extended heparin chain lengths

  10. A comparison of recombinant thrombin to bovine thrombin as a hemostatic ancillary in patients undergoing peripheral arterial bypass and arteriovenous graft procedures.

Pig (Porcine) Coagulation Factor II (thrombin) (F2) interaction partners

  1. thrombin stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (Montrer UGDH Anticorps) and by receptor-mediated up-regulation of factor XIII (Montrer UGDH Anticorps) synthesis

  2. The great similarity of prothrombin among rhesus, human, and porcine confirm the great value of the pig-to-rhesus xenotransplantation model.

  3. In conclusion, thrombin activates pro-MMP-2 (Montrer MMP2 Anticorps) in the absence of elevated pro-MMP-2 (Montrer MMP2 Anticorps) expression and secretion in CSMCs, and thrombin induces CSMC mitogenesis involving its action on MMP-2 (Montrer MMP2 Anticorps)

  4. Thrombin stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1 (Montrer F2R Anticorps), RhoA (Montrer RHOA Anticorps), and myocardin (Montrer MYOCD Anticorps).

Prothrombin (F2) profil antigène

Antigen Summary

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Alternative names and synonyms associated with Prothrombin (F2)

  • coagulation factor II (thrombin) (f2) anticorps
  • coagulation factor II (thrombin) (F2) anticorps
  • cell division cycle 34 (Cdc34) anticorps
  • chymase 1, mast cell (CMA1) anticorps
  • coagulation factor II (F2) anticorps
  • complement component 1, s subcomponent (C1s) anticorps
  • HtrA serine peptidase 1 (Htra1) anticorps
  • HtrA serine peptidase 2 (HTRA2) anticorps
  • melanoma antigen family B, 17-like (LOC783975) anticorps
  • prothrombin-like (LOC100856539) anticorps
  • serine protease (HTRA) anticorps
  • THROMBIN protein (THROMBIN) anticorps
  • AA959438 anticorps
  • AI255193 anticorps
  • AI327365 anticorps
  • C1sa anticorps
  • Cf-2 anticorps
  • Cf2 anticorps
  • F2 anticorps
  • FII anticorps
  • HTRA anticorps
  • HTRA1 anticorps
  • prothrombin anticorps
  • PT anticorps
  • RPRGL2 anticorps
  • THPH1 anticorps
  • thrombin anticorps
  • wu:fb57c10 anticorps
  • wu:fd42e09 anticorps
  • wu:fd59d01 anticorps
  • zgc:66319 anticorps

Protein level used designations for F2

prothrombin , cell division cycle 34 homolog , serine protease , ubiquitin-conjugating enzyme Cdc34 , ubiquitin-conjugating enzyme E2 R1 , alpha-chymase , chymase , mast cell chymase , mast cell protease I , coagulation factor 2 , thrombin , prepro-coagulation factor II , prothrombin B-chain , C1 esterase , complement C1s-A subcomponent , complement component 1 subcomponent s-A , complement component C1SA

GENE ID SPECIES
325881 Danio rerio
712729 Macaca mulatta
299602 Rattus norvegicus
490628 Canis lupus familiaris
14061 Mus musculus
29251 Rattus norvegicus
2147 Homo sapiens
280685 Bos taurus
100144442 Sus scrofa
395306 Gallus gallus
100725988 Cavia porcellus
100307041 Ovis aries
50908 Mus musculus
100716225 Cavia porcellus
395990 Gallus gallus
783975 Bos taurus
100856539 Canis lupus familiaris
100008705 Oryctolagus cuniculus
100009146 Oryctolagus cuniculus
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