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anti-Human Aurora Kinase B Anticorps:
anti-Mouse (Murine) Aurora Kinase B Anticorps:
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Human Polyclonal Aurora Kinase B Primary Antibody pour ICC, IF - ABIN151760
Adams, Eckley, Vagnarelli, Wheatley, Gerloff, Mackay, Svingen, Kaufmann, Earnshaw: Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells. dans Chromosoma 2001
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Human Monoclonal Aurora Kinase B Primary Antibody pour IF, WB - ABIN968357
Chen, Jin, Tahir, Zhang, Liu, Sarthy, McGonigal, Liu, Rosenberg, Ng: Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells. dans The Journal of biological chemistry 2002
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Human Monoclonal Aurora Kinase B Primary Antibody pour IF, WB - ABIN968358
Lange, Rebollo, Herold, González: Cdc37 is essential for chromosome segregation and cytokinesis in higher eukaryotes. dans The EMBO journal 2002
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Human Polyclonal Aurora Kinase B Primary Antibody pour ICC, IF - ABIN152999
Qi, Tang, Yu: Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1. dans Molecular biology of the cell 2006
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Human Monoclonal Aurora Kinase B Primary Antibody pour ELISA, WB - ABIN1724660
Song, So, Cheng, Tang, Croft: Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion. dans Immunity 2005
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Human Monoclonal Aurora Kinase B Primary Antibody pour ELISA, WB - ABIN965626
Kapoor, Lavoie, Frappier: EBP2 plays a key role in Epstein-Barr virus mitotic segregation and is regulated by aurora family kinases. dans Molecular and cellular biology 2005
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Human Polyclonal Aurora Kinase B Primary Antibody pour ELISA, WB - ABIN129612
Mackay, Makise, Ullman: Defects in nuclear pore assembly lead to activation of an Aurora B-mediated abscission checkpoint. dans The Journal of cell biology 2010
Human Polyclonal Aurora Kinase B Primary Antibody pour EIA, WB - ABIN117978
Honda, Asato, Tanaka, Endo, Nishimura, Ito: Vidian nerve schwannoma with middle cranial fossa extension resected via a maxillary swing approach. dans Head & neck 2008
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Human Polyclonal Aurora Kinase B Primary Antibody pour WB - ABIN2441645
Bailey, Fields, Cheng, Lee, Wagenaar, Lagrois, Schmidt, Xia, Ma: WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission. dans The Journal of biological chemistry 2015
Human Polyclonal Aurora Kinase B Primary Antibody pour ELISA, WB - ABIN1043878
Wheatley, Henzing, Dodson, Khaled, Earnshaw: Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo. dans The Journal of biological chemistry 2004
Aurora A (Montrer AURKA Anticorps) and B kinases directly phosphorylate Lgl to promote its mitotic relocalization.
Regulation of Polo (Montrer PLK1 Anticorps) by Aurora B and Map205 is required for cytokinesis.
We propose that mutual inhibitions between Aurora B a (Montrer CDK1 Anticorps)nd Cyclin B regulate the duration of abscission and thereby the number of sister cells in each cyst.
Aurora B kinase activity is not required during contractile ring ingression, providing insight into the mechanism of cytokinesis.
Aurora B interacts with and requires the Cdc37 (Montrer CDC37 Anticorps)/Hsp90 (Montrer HSP90 Anticorps) complex for its stability.
INCENP (Montrer INCENP Anticorps) binds to the cohesion protector protein (Montrer PRDX2 Anticorps) MEI-S332, which is also an excellent in vitro substrate for Aurora B kinase.
The results of experiment indicated that specific knockdown of Aurora kinase B led to prostate carcinoma cells apoptosis and inhibited tumor growth.
decrease in Aurora B results in diminished binding of the chromokinesin Kif4A to chromosome arms.
Aurora B kinase interacts with and phosphorylates Sgo1 (Montrer SGOL1 Anticorps). Aurora B-mediated phosphorylation of Sgo1 (Montrer SGOL1 Anticorps) regulates the distribution of Sgo1 (Montrer SGOL1 Anticorps) between centromeres and chromosome arms.
AURKC (Montrer AURKC Anticorps) rs758099 TT and (CC + CT) genotypes were positively associated with increased intestinal type gastric cancer (GC)risk, but not with an increased diffuse type GC risk. Based on these results, we can conclude that AURKA (Montrer AURKA Anticorps) rs1047972 and AURKC (Montrer AURKC Anticorps) rs758099 polymorphisms could affect the risk of GC development.
Aurora-C (Montrer AURKC Anticorps) interactions with members of the Chromosome Passenger Complex (CPC), Survivin (Montrer BIRC5 Anticorps) and Inner Centromere Protein (INCENP (Montrer INCENP Anticorps)) in reference to known Aurora-B interactions to understand the functional significance of Aurora-C (Montrer AURKC Anticorps) overexpression in human cancer cells, is reported.
Aurora kinase (Montrer AURKA Anticorps) inhibitor danusertib negatively regulated AURKB/p70S6K (Montrer RPS6KB1 Anticorps)/RPL15 (Montrer RPL15 Anticorps) axis with the involvement of PI3K (Montrer PIK3CA Anticorps)/Akt (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps), AMPK (Montrer PRKAA1 Anticorps), and p38 MAPK (Montrer MAPK14 Anticorps) signaling pathways, leading to the induction of apoptosis and autophagy in human leukemia cells.
The kinase activity of Aurora B on serine 31 of histone H3.3 (Montrer H3F3A Anticorps) was biochemically confirmed with nucleosomal substrates in vitro.
in addition to its role in checkpoint signaling, MAD2 (Montrer MAD2L1 Anticorps) ensures chromosome stability through the regulation of AURORA B.
Ska promotes Aurora B activity to limit its own microtubule and kinetochore association.
partial co-localization of AKT3 (Montrer AKT3 Anticorps) with AURKB was observed during anaphase. Overall, this study suggests that AKT3 (Montrer AKT3 Anticorps) could repress the antiproliferative effects of AURKi, with a novel activity particularly suppressing the aneuploidy induction.
Aurkb phosphorylates Oct4 (Montrer POU5F1 Anticorps)(S229) during G2/M phase, leading to the dissociation of Oct4 (Montrer POU5F1 Anticorps) from chromatin, whereas PP1 (Montrer PPP1CC Anticorps) binds Oct4 (Montrer POU5F1 Anticorps) and dephosphorylates Oct4 (Montrer POU5F1 Anticorps)(S229) during M/G1 transition, which resets Oct4 (Montrer POU5F1 Anticorps)-driven transcription for pluripotency and the cell cycle.
Overexpression of Aurora B (Montrer AURKC Anticorps) also results in a reduced DNA damage response and decreased levels of the p53 (Montrer TP53 Anticorps) target p21(Cip1 (Montrer CDKN1A Anticorps)) in vitro and in vivo.
Chromsome stability is on of the tumor-suppressive functions of ARF (Montrer CDKN2A Anticorps) as well as regulation of Aurora B (Montrer AURKC Anticorps) expression in tumors.
Using this mutant we show for the first time that AURKC has functions that do not overlap with AURKB. These functions include regulating localized CPC activity and regulating chromosome alignment and K-MT attachments at metaphase of meiosis I (Met I).
reduced accumulation of Aurora B (Montrer AURKC Anticorps) at the inner centromere region in cells lacking Pds5B (Montrer PDS5B Anticorps) impairs its error correction function, promoting chromosome mis (Montrer AMH Anticorps)-segregation and aneuploidy
Aurora B (Montrer AURKC Anticorps) and Ring1B (Montrer RNF2 Anticorps) co-occupy active promoters in resting lymphocytes.
FBXL2 (Montrer FBXL2 Anticorps) mediates Aurora B (Montrer AURKC Anticorps) ubiquitination and degradation within the midbody, which is sufficient to induce mitotic arrest and apoptosis.
Inhibitions of Aurora B (Montrer AURKC Anticorps) and Cyclin-dependent kinase 1 (Montrer CDK1 Anticorps) activity in vertebrate cells also have opposite effects on the timing of abscission.
Aurora B (Montrer AURKC Anticorps) represses p21(Cip1 (Montrer CDKN1A Anticorps)), preventing delayed DNA replication, Cdk (Montrer CDK4 Anticorps) inhibition and premature mitotic exit.
Calmodulin protects Aurora B (Montrer AURKC Anticorps) on the midbody to regulate the fidelity of cytokinesis.
Alterations in PGRMC1 (Montrer PGRMC1 Anticorps) and/or AURKB localization account in part for the increased aneuploidy and low development competence of oocytes from ovaries with reduced antral follicle counts.
AURKB associated with metaphase chromosomes.
Aurora B kinase is essential for furrow induction and maturation in the zebrafish embryo.
This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding different isoforms have been found for this gene.
, aurora B
, aurora B kinase
, dAurora B
, aurora/IPL1-related kinase 2
, serine/threonine-protein kinase 12
, serine/threonine-protein kinase aurora-B
, aurora kinase B
, serine/threonine-protein kinase 12-like
, aurora 1
, aurora kinase B-Sv1
, aurora kinase B-Sv2
, aurora- and Ipl1-like midbody-associated protein 1
, aurora-related kinase 2
, protein phosphatase 1, regulatory subunit 48
, serine/threonine kinase 12
, serine/threonine-protein kinase 5
, aurora- and IPL1-like midbody-associated protein 1
, serine/threonine kinase 5
, Serine/threonine-protein kinase 12
, cellular island
, serine/threonine kinase a
, I-kappa-B kinase 2
, I-kappa-B-kinase beta
, inhibitor of kappaB kinase beta
, inhibitor of nuclear factor kappa B kinase beta subunit
, inhibitor of nuclear factor kappa-B kinase subunit beta
, nuclear factor NF-kappa-B inhibitor kinase beta