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Aperçu des produits pour anti-CD247 (CD247) Anticorps

Full name:
anti-CD247 Molecule Anticorps (CD247)
Chez www.anticorps-enligne.fr sont 285 CD247 Molecule (CD247) Anticorps de 24 de différents fournisseurs disponibles. De plus, nous expédions CD247 Protéines (12) et CD247 Kits (6) et beaucoup plus de produits pour cette protéine. Un total de 314 CD247 produits sont actuellement listés.
Synonymes:
4930549J05Rik, A430104F18Rik, AW552088, Cd3, Cd3-eta, CD3-ZETA, CD3H, CD3Q, Cd3z, Cd3zeta, CD247, im:7156386, LOC100136514, LOC100136549, LOC100305023, T3Z, Tcrk, TCRZ, TCRzeta

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anti-Mouse (Murine) CD247 Anticorps:

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anti-CD247 Anticorps mieux référencés

  1. Human Polyclonal CD247 Primary Antibody pour IHC (fro), IHC (p) - ABIN115429 : Henry, Bennett, Piggott, Levett, May, Westley: Expression of the pNR-2/pS2 protein in diverse human epithelial tumours. dans British journal of cancer 1991 (PubMed)
    Show all 5 references for ABIN115429

  2. Human Polyclonal CD247 Primary Antibody pour WB - ABIN4620516 : Miyagawa, Yamai, Sakaguchi, Kiyohara, Tsukamoto, Kimoto, Nakamura, Lee, Tsai, Chiang, Shimoda, Harada, Tahira, Hayashi, Horiuchi: Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus. dans Rheumatology (Oxford, England) 2008 (PubMed)
    Show all 3 references for ABIN4620516

  3. Mouse (Murine) Monoclonal CD247 Primary Antibody pour FACS - ABIN4898315 : Lin, Xu, Jin, Zhong, Di, Lin: CXCL12 enhances exogenous CD4+CD25+ T cell migration and prevents embryo loss in non-obese diabetic mice. dans Fertility and sterility 2009 (PubMed)
    Show all 2 references for ABIN4898315

  4. Human Monoclonal CD247 Primary Antibody pour IP, WB - ABIN967304 : Hussey, Clayton, Diener, McConkey, Howard, Rodewald, DAdamio, Dallenbach, Stein, Schmidt: Overexpression of CD3 eta during thymic development does not alter the negative selection process. dans Journal of immunology (Baltimore, Md. : 1950) 1993 (PubMed)

  5. Human Monoclonal CD247 Primary Antibody pour EIA, IHC (fro) - ABIN118361 : van Oers, Teh, Irving, Tiong, Weiss, Teh: Production and characterization of monoclonal antibodies specific for the murine T cell receptor zeta chain. dans Journal of immunological methods 1994 (PubMed)

  6. Mouse (Murine) Monoclonal CD247 Primary Antibody pour FACS - ABIN4898307 : Lemay, Rintoul, Kus, Paterson, Garcia, Falls, Ferreira, Bridle, Conrad, Tang, Diallo, Arulanandam, Le Boeuf, Garson, Vanderhyden, Stojdl, Lichty, Atkins, Parato, Bell, Auer: Harnessing oncolytic virus-mediated antitumor immunity in an infected cell vaccine. dans Molecular therapy : the journal of the American Society of Gene Therapy 2012 (PubMed)

Plus d’anticorps contre CD247 partenaires d’interaction

Zebrafish CD247 Molecule (CD247) interaction partners

  1. The structure of the adaptor protein cd3zeta has been identified in the zebrafish genome.

Mouse (Murine) CD247 Molecule (CD247) interaction partners

  1. Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 (Montrer CCR7 Anticorps) and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice

  2. There is an early (within seconds) interaction between CD3zeta and the coreceptor CD8 that is independent of the binding of CD8 to MHC.

  3. The resting TCR localized in the disordered domain of giant plasma membrane (PM) vesicles (GPMVs) and PM spheres (PMSs) and single and nanoclustered TCRs are found in the high-density fractions in sucrose gradients.

  4. When Ly108 (Montrer SLAMF6 Anticorps) is engaged in trans during cell-cell interactions, Ly108 (Montrer SLAMF6 Anticorps)-CD3zeta interactions are promoted in a manner that uniquely depends on Ly108 (Montrer SLAMF6 Anticorps) TM domain, leading to more efficient CD3zeta dephosphorylation.

  5. Two transcription factor binding sites and a long non-coding RNA are identified within the Cd247 gene.

  6. Zfat (Montrer ZFAT Anticorps)-deficiency results in a loss of CD3zeta phosphorylation with dysregulation of ERK (Montrer EPHB2 Anticorps) and Egr (Montrer EGR1 Anticorps) activities leading to impaired positive selection.

  7. The results of this study supported the model that the procognitive function of CD3zeta may be mediated through its involvement in the NMDAR (Montrer GRIN1 Anticorps) downstream signaling pathway leading to CaMKII (Montrer CAMK2G Anticorps)-dependent LTP (Montrer SCP2 Anticorps) induction.

  8. T cell CD3zeta deficiency enables multiorgan tissue inflammation.

  9. Tyrosine phosphorylation of the TCR-zeta cytoplasmic domain regulates its association with the plasma membrane

  10. The data of this study suggested that CD3zeta mediates the ZAP-70 (Montrer ZAP70 Anticorps)/Syk (Montrer SYK Anticorps) kinase activation triggered by ephrinA-activated pathway to regulate early neuronal morphogenesis.

Human CD247 Molecule (CD247) interaction partners

  1. Linkage and association studies revealed a chromosomal region in which a novel type 1 diabetes (T1D)/autoimmune thyroid disease (AITD) susceptibility gene, CD247, is located and showed association between T1D/AITD and several variants in this gene. These results suggests that common susceptibility genes act in concert with variants of CD247 to generate genetic risk for T1D/AITD in this population.

  2. Suggest 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-zeta chain down-regulation via caspase-3 (Montrer CASP3 Anticorps) activation in oral cancer.

  3. SRSF1 (Montrer SRSF1 Anticorps) regulates CD3zeta expression in human T cells and may contribute to the T cell defect in systemic lupus erythematosus.

  4. In localized colorectal cancer carriers, mRNA-based CD3Z/CD8 (Montrer CD8A Anticorps) profiling of tumor immune response may have stage, site and tissue-specific prognostic significance, along with ESR1 (Montrer ESR1 Anticorps) expression.

  5. Our study independently confirms and extends the association of SLE with CD247, which is shared by various autoimmune disorders and supports a common T-cell-mediated mechanism.

  6. we observed decreased CD3 (Montrer CD3 Anticorps) surface expression, reduced ZAP-70 (Montrer ZAP70 Anticorps) abundance and increased histone H3 (Montrer HIST3H3 Anticorps)-acetylation in activated T lymphocytes after 5 minutes of clinorotation and a transient downregulation of CD3 (Montrer CD3 Anticorps) and stable downregulation of IL-2R

  7. T cell receptor (TCR)-CD3 (Montrer CD3 Anticorps) complex and the Lck (Montrer LCK Anticorps) kinase were required for Ca(2 (Montrer CA2 Anticorps)+) mobilization but not for apoptosis induction in Jurkat cells.

  8. These findings confirm the role of PTPN22 (Montrer PTPN22 Anticorps) and CD28 (Montrer CD28 Anticorps) involved in the T cell activation pathway in the development of T1D in Tunisian families. Interestingly, ZAP70 (Montrer ZAP70 Anticorps) and TCRbeta/CD3z seem to contribute to the susceptibility to the disease in our population.

  9. a CD247 defect leads to the accumulation of naive, hyporesponsive gammadelta and alphabeta T cells in thymoma patient resulting in a novel type of acquired T cell immunodeficiency and immune dysregulation of clinical significance.

  10. CD247 downregulation was associated with disease severity, complications, and the occurrence of future cardiovascular events, suggesting its potential use not only as a diagnostic but also as a prognostic biomarker.

Pig (Porcine) CD247 Molecule (CD247) interaction partners

CD247 profil antigène

Antigen Summary

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with CD247

  • CD247 antigen like (cd247l) anticorps
  • CD3zeta-2 (LOC100136514) anticorps
  • CD3zeta-1 (LOC100136549) anticorps
  • CD3 zeta (LOC100305023) anticorps
  • CD247 molecule (CD247) anticorps
  • CD247 antigen (cd247) anticorps
  • CD247 antigen (Cd247) anticorps
  • Cd247 molecule (Cd247) anticorps
  • 4930549J05Rik anticorps
  • A430104F18Rik anticorps
  • AW552088 anticorps
  • Cd3 anticorps
  • Cd3-eta anticorps
  • CD3-ZETA anticorps
  • CD3H anticorps
  • CD3Q anticorps
  • Cd3z anticorps
  • Cd3zeta anticorps
  • CD247 anticorps
  • im:7156386 anticorps
  • LOC100136514 anticorps
  • LOC100136549 anticorps
  • LOC100305023 anticorps
  • T3Z anticorps
  • Tcrk anticorps
  • TCRZ anticorps
  • TCRzeta anticorps

Protein level used designations for anti-CD247 Molecule (CD247) Anticorps

CD247 antigen like , cd3zetal , CD3zeta-like , CD247 antigen-like , CD3zeta-2 , T-cell surface glycoprotein CD3 zeta chain , CD3zeta-1 , CD3 zeta , CD247 molecule , cd3zeta , CD3 antigen, zeta polypeptide , CD3-zeta/eta , T-cell receptor T3 eta chain , CD247 antigen, zeta subunit , CD3Z antigen, zeta polypeptide (TiT3 complex) , CD3zeta chain , T-cell antigen receptor complex, zeta subunit of CD3 , T-cell receptor T3 zeta chain , TCR zeta chain , CD247 antigen , T-cell receptor CD3 subunit zeta , T-cell receptor CD3, subunit zeta , CD3 zeta chain , CD3 Zeta chain

GENE ID SPECIES
100101465 Danio rerio
100136514 Salmo salar
100136549 Salmo salar
100305023 Ictalurus punctatus
748272 Pan troglodytes
100101654 Danio rerio
12503 Mus musculus
919 Homo sapiens
25300 Rattus norvegicus
397302 Sus scrofa
100008617 Oryctolagus cuniculus
443436 Ovis aries
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