anti-Non-Human Primate CD28 anticorps pour Immunoprecipitation

Recommended CD28 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
CD28 Anticorps
  • Tp44
  • CD28RNA
  • CD28 molecule
  • CD28 antigen
  • Cd28 molecule
  • CD28
  • Cd28
Reactivité
Humain, Non-Human Primate
478
390
103
70
51
34
27
26
25
22
15
6
3
3
3
2
1
1
1
Hôte
Souris
510
194
91
70
40
29
12
1
Clonalité
Monoclonal
Conjugué
Cet anticorp CD28 est non-conjugé
111
94
72
37
20
19
18
18
17
16
16
12
12
12
12
11
10
10
8
7
6
6
6
6
6
5
4
3
3
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP), Western Blotting (WB)
760
210
185
148
143
139
128
127
88
72
26
13
13
9
8
5
4
3
3
3
3
3
2
2
2
1
1
1
1
1
1
Options
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N° du produit ABIN638435
198,00 €
Plus frais de livraison 40,00 € et TVA
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN775705 FACS Func ICC IHC (f) IP WB Mouse IgG1 Connectez-vous pour afficher CD28-2 5
1 ABIN457388 FACS Func ICC IHC (f) IP WB PerCP Mouse IgG1 Connectez-vous pour afficher CD28-2 6
1 ABIN349705 FACS Func ICC IHC (f) IP WB APC Mouse IgG1 Connectez-vous pour afficher CD28-2 6
1 ABIN349707 FACS Func ICC IHC (f) IP WB FITC Mouse IgG1 Connectez-vous pour afficher CD28-2 4
1 ABIN349710 FACS Func ICC IHC (f) IP WB PE Mouse IgG1 Connectez-vous pour afficher CD28-2 6

anti-CD28 anticorps pour Immunoprecipitation mieux référencés

anti-CD28 Anticorps

Application / Reactivité Non-Human Primate Humain
Flow Cytometry (FACS) 7 Anticorps 352 Anticorps
Functional Studies (Func) 6 Anticorps 48 Anticorps
Immunocytochemistry (ICC) 6 Anticorps 108 Anticorps
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 6 Anticorps
Immunoprecipitation (IP) 6 Anticorps
Western Blotting (WB) 6 Anticorps
Activation (Act) 1 Anticorps
Agonist (Agon) 3 Anticorps
Biochemical Assay (BCA) 3 Anticorps
Cell Culture (CC) 1 Anticorps
Cytometry by Time of Flight (CyTOF) 10 Anticorps
ELISA 123 Anticorps
ELISA (Detection) 1 Anticorps
Enzyme Immunoassay (EIA) 1 Anticorps

General

Antigène CD28 Anticorps
Reactivité Humain, Non-Human Primate
(478), (390), (103), (70), (51), (34), (27), (26), (25), (22), (15), (6), (3), (3), (3), (2), (1), (1), (1)
Hôte Souris
(510), (194), (91), (70), (40), (29), (12), (1)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp CD28 est non-conjugé
(111), (94), (72), (37), (20), (19), (18), (18), (17), (16), (16), (12), (12), (12), (12), (11), (10), (10), (8), (7), (6), (6), (6), (6), (6), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2)
Application Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP), Western Blotting (WB)
(760), (210), (185), (148), (143), (139), (128), (127), (88), (72), (26), (13), (13), (9), (8), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 7 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-CD28 anticorps

Détail du antigène CD28 Information d'application Stockage ProductDetails: References for anti-CD28 antibody (ABIN638435) Images
Specificité The antibody CD28.2 reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.
HLDA V., WS Code 5T CD28.05
Purification Purified from hybridoma culture supernatant by protein-A affinity chromatography.
Pureté > 95 % (by SDS-PAGE)
Stérilité 0.2 μm filtered
niveau d'endotoxine Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
Immunogène DC28.1.3.3 murine T cell hybridoma transfected with human CD28 cDNA
Clone CD28-2
Isotype IgG1

Détail du antigène CD28

Détail du produit anti-CD28 anticorps Information d'application Stockage ProductDetails: References for anti-CD28 antibody (ABIN638435) Images Haut de la page
Antigène
Autre désignation CD28 (CD28 Antibody Extrait)
Sujet CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
ID gène 940
Domaine de recherche Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells, Apoptosis/Necrosis
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Information d'application

Détail du produit anti-CD28 anticorps Détail du antigène CD28 Stockage ProductDetails: References for anti-CD28 antibody (ABIN638435) Images Haut de la page
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Stockage

Détail du produit anti-CD28 anticorps Détail du antigène CD28 Information d'application ProductDetails: References for anti-CD28 antibody (ABIN638435) Images Haut de la page
Concentration 1 mg/mL
Buffer Azide free phosphate buffered saline (PBS), approx. pH 7.4.
Conseil sur la manipulation Do not freeze.
Stock 4 °C
Stockage commentaire Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.

ProductDetails: References for anti-CD28 antibody (ABIN638435)

Détail du produit anti-CD28 anticorps Détail du antigène CD28 Information d'application Stockage Images Haut de la page
Produit citée dans:

Scharschmidt, Wegener, Heissmeyer, Rao, Krappmann: "Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling." dans: Molecular and cellular biology, Vol. 24, Issue 9, pp. 3860-73, 2004

Jeong, Qiao, Nascimbeni, Hu, Rehermann, Murthy, Liang: "Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates." dans: Journal of virology, Vol. 78, Issue 13, pp. 6995-7003, 2004

Marti, Krause, Post, Lyddane, Dupont, Sadelain, King: "Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 1, pp. 197-206, 2001

Galea-Lauri, Darling, Gan, Krivochtchapov, Kuiper, Gäken, Souberbielle, Farzaneh: "Expression of a variant of CD28 on a subpopulation of human NK cells: implications for B7-mediated stimulation of NK cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 1, pp. 62-70, 1999

Tazi, Moreau, Bergeron, Dominique, Hance, Soler: "Evidence that Langerhans cells in adult pulmonary Langerhans cell histiocytosis are mature dendritic cells: importance of the cytokine microenvironment." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 6, pp. 3511-5, 1999

Nunes, Klasen, Franco, Lipcey, Mawas, Bagnasco, Olive: "Signalling through CD28 T-cell activation pathway involves an inositol phospholipid-specific phospholipase C activity." dans: The Biochemical journal, Vol. 293 ( Pt 3), pp. 835-42, 1993

Background publications

Nunès, Klasen, Ragueneau, Pavon, Couez, Mawas, Bagnasco, Olive: "CD28 mAbs with distinct binding properties differ in their ability to induce T cell activation: analysis of early and late activation events." dans: International immunology, Vol. 5, Issue 3, pp. 311-5, 1993

Images

Détail du produit anti-CD28 anticorps Détail du antigène CD28 Information d'application Stockage ProductDetails: References for anti-CD28 antibody (ABIN638435) Haut de la page
Supplier Images
Flow Cytometry (FACS) image for anti-CD28 anticorps (CD28) (ABIN638435) Surface staining of human peripheral blood leukocytes with anti-human CD28 (CD28.2) p...