anti-Humain CREB1 anticorps pour Dot Blot

Recommended CREB1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
CAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein 1a
  • cyclic AMP response element binding protein
  • CREB1
  • creb1
  • Creb1
  • LOC100351999
  • creb1a
  • CREB
Épitope
pSer133
141
38
38
37
22
20
16
15
15
9
8
7
7
6
6
5
5
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain, Souris, Rat (Rattus)
548
328
298
41
38
36
30
27
26
26
19
17
15
12
7
7
7
2
1
1
1
1
Hôte
Lapin
449
101
11
1
Clonalité
Polyclonal
Conjugué
Cet anticorp CREB1 est non-conjugé
18
15
15
7
7
6
6
6
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
Application
Dot Blot (DB), Western Blotting (WB)
441
225
192
100
92
47
44
42
31
11
11
10
4
3
3
2
2
1
1
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N° du produit ABIN265094
517,00 €
Plus frais de livraison 40,00 € et TVA

General

Antigène CAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
Épitope pSer133
(141), (38), (38), (37), (22), (20), (16), (15), (15), (9), (8), (7), (7), (6), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain, Souris, Rat (Rattus)
(548), (328), (298), (41), (38), (36), (30), (27), (26), (26), (19), (17), (15), (12), (7), (7), (7), (2), (1), (1), (1), (1)
Hôte Lapin
(449), (101), (11), (1)
Clonalité
Polyclonal
Conjugué Cet anticorp CREB1 est non-conjugé
(18), (15), (15), (7), (7), (6), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Dot Blot (DB), Western Blotting (WB)
(441), (225), (192), (100), (92), (47), (44), (42), (31), (11), (11), (10), (4), (3), (3), (2), (2), (1), (1)
Pubmed 6 références disponible
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Détail du produit anti-CREB1 anticorps

Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN265094) Images
Specificité This antibody reacts to CREB (pSer133).
Purification Immunoaffinity Chromatography.
Immunogène Synthetic phosphopeptide corresponding to amino acid residues surrounding the phosphorylated Ser133 of CREB.
Isotype IgG

Détail du antigène CREB1

Détail du produit anti-CREB1 anticorps Information d'application Stockage References for anti-CREB1 antibody (ABIN265094) Images Haut de la page
Antigène
Autre désignation CREB1 (CREB1 Antibody Extrait)
Sujet It is well known that the control of gene expression involves activation of protein kinase cascades that regulate transcription factors within the nucleus. The cyclic AMP response element binding protein (CREB) is one of the best characterized stimulusinduced transcription factors. This transcription factor is a component of intracellular signaling events that regulate a wide range of biological functions, from spermatogenesis to circadian rhythms and memory. A variety of protein kinases including protein kinase A (PKA), mitogenactivated protein kinases (MAPKs), and Ca2+/calmodulin-dependent protein kinases (CaMKs) phosphorylate CREB at serine 133 (Ser133), and phosphorylation of Ser133 is required for CREB mediated transcription.Synonyms: CREB-1, Cyclic AMP-responsive element-binding protein 1, cAMP-responsive element-binding protein 1
ID gène 1385
NCBI Accession NP_004370
UniProt P16220
Pathways Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation

Information d'application

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Stockage References for anti-CREB1 antibody (ABIN265094) Images Haut de la page
Indications d'application Suitable for use in Western Blot and Dot Blot (1/1000). Positive Control/Tissue Expression: Rat brain lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application References for anti-CREB1 antibody (ABIN265094) Images Haut de la page
Buffer HEPES ( pH 7.5) solution containing 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock -20 °C
Stockage commentaire Store the antibody (in aliquots) at -20 °C to -70 °C.

References for anti-CREB1 antibody (ABIN265094)

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage Images Haut de la page
Background publications

Johannessen, Delghandi, Moens: "What turns CREB on?" dans: Cellular signalling, Vol. 16, Issue 11, pp. 1211-27, 2004

Shaywitz, Greenberg: "CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals." dans: Annual review of biochemistry, Vol. 68, Issue 2, pp. 821-61, 2000

Abel, Kandel: "Positive and negative regulatory mechanisms that mediate long-term memory storage." dans: Brain research. Brain research reviews, Vol. 26, Issue 2-3, pp. 360-78, 1998

Silva, Kogan, Frankland, Kida: "CREB and memory." dans: Annual review of neuroscience, Vol. 21, pp. 127-48, 1998

Montminy: "Transcriptional regulation by cyclic AMP." dans: Annual review of biochemistry, Vol. 66, pp. 807-22, 1997

Bird: "The essentials of DNA methylation." dans: Cell, Vol. 70, Issue 1, pp. 5-8, 1992

Images

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN265094) Haut de la page
Supplier Images
 image for anti-CAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody (ABIN265094) anti-CAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody