anti-Humain CREB1 anticorps pour Enzyme Immunoassay

Recommended CREB1 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
CAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
  • creb
  • CREB1
  • Creb1
  • CREB
  • 2310001E10Rik
  • 3526402H21Rik
  • AV083133
  • Creb
  • Creb-1
  • creb1
  • zgc:55598
  • cAMP responsive element binding protein 1
  • cAMP responsive element binding protein 1a
  • cyclic AMP response element binding protein
  • CREB1
  • creb1
  • Creb1
  • LOC100351999
  • creb1a
  • CREB
Épitope
pSer133
141
38
38
37
22
20
16
15
15
9
8
7
7
6
6
5
5
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
548
329
299
41
38
36
30
27
26
26
19
17
15
12
7
7
7
2
1
1
1
1
Hôte
Lapin
449
101
11
1
Clonalité
Polyclonal
Conjugué
Cet anticorp CREB1 est non-conjugé
18
15
15
7
7
6
6
6
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
441
225
192
100
91
47
44
42
31
11
10
10
4
3
3
2
2
1
1
1
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N° du produit ABIN358113
407,00 €
Plus frais de livraison 40,00 € et TVA
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
1 ABIN116948 EMSA EIA IP WB Rabbit N-Term Connectez-vous pour afficher Polyclonal 1
1 ABIN126754 EIA WB Mouse IgG1 pSer133 Connectez-vous pour afficher 1-00E-010
1 ABIN265371 EIA IHC (p) WB Rabbit Connectez-vous pour afficher Polyclonal
1 ABIN5556654 EIA IP WB Rabbit pSer133 Connectez-vous pour afficher Polyclonal
1 ABIN5556215 EIA FACS IF WB Rabbit Ig Fraction AA 112-140, Middle Region Connectez-vous pour afficher Polyclonal
1 ABIN782353 EIA IF IHC (p) WB Mouse IgG1 AA 1-342 Connectez-vous pour afficher 3F1-1B2
1 ABIN782354 EIA IHC (p) WB Mouse IgG2a AA 1-342 Connectez-vous pour afficher 5F2
1 ABIN1106831 EIA IF IHC (p) WB Mouse IgG1 Connectez-vous pour afficher 5G3 4
1 ABIN452618 EIA Mouse IgG1 pSer133 Connectez-vous pour afficher A3A4
1 ABIN452620 EIA Mouse IgG2b pSer133 Connectez-vous pour afficher B1C4

General

Antigène CAMP Responsive Element Binding Protein 1 (CREB1) Anticorps
Épitope pSer133
(141), (38), (38), (37), (22), (20), (16), (15), (15), (9), (8), (7), (7), (6), (6), (5), (5), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivité Humain
(548), (329), (299), (41), (38), (36), (30), (27), (26), (26), (19), (17), (15), (12), (7), (7), (7), (2), (1), (1), (1), (1)
Hôte Lapin
(449), (101), (11), (1)
Clonalité
Polyclonal
Conjugué Cet anticorp CREB1 est non-conjugé
(18), (15), (15), (7), (7), (6), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(441), (225), (192), (100), (91), (47), (44), (42), (31), (11), (10), (10), (4), (3), (3), (2), (2), (1), (1), (1)
Pubmed 5 références disponible
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Détail du produit anti-CREB1 anticorps

Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN358113) Images
Specificité This antibody detects CREB pSer133. Predicted to cross react with Mouse (100 % Antigen Homology).
Purification Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogène This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S133 of human CREB.
Isotype Ig

Détail du antigène CREB1

Détail du produit anti-CREB1 anticorps Information d'application Stockage References for anti-CREB1 antibody (ABIN358113) Images Haut de la page
Antigène
Autre désignation CREB1 (CREB1 Antibody Extrait)
Sujet CREB is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, (CRE), a sequence present in many viral and cellular promoters. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.Synonyms: CREB-1, Cyclic AMP-responsive element-binding protein 1, cAMP-responsive element-binding protein 1
Poids moléculaire 36688 Da
ID gène 1385, 9606
UniProt P16220
Pathways Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation

Information d'application

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Stockage References for anti-CREB1 antibody (ABIN358113) Images Haut de la page
Indications d'application ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Stockage

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application References for anti-CREB1 antibody (ABIN358113) Images Haut de la page
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-CREB1 antibody (ABIN358113)

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage Images Haut de la page
Background publications

Samten, Howard, Weis, Wu, Shams, Townsend, Safi, Barnes: "Cyclic AMP response element-binding protein positively regulates production of IFN-gamma by T cells in response to a microbial pathogen." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 10, pp. 6357-63, 2005

Zhang, Odom, Koo, Conkright, Canettieri, Best, Chen, Jenner, Herbolsheimer, Jacobsen, Kadam, Ecker, Emerson, Hogenesch, Unterman, Young, Montminy: "Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 12, pp. 4459-64, 2005

Cho, Choi, Kim, Baek, Chung, Moon, Kim, Lee, Koo, Yoon: "Prostaglandin E2 induces MUC8 gene expression via a mechanism involving ERK MAPK/RSK1/cAMP response element binding protein activation in human airway epithelial cells." dans: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 6676-81, 2005

Bailey, Tyson-Capper, Gilmore, Robson, Europe-Finner: "Identification of human myometrial target genes of the cAMP pathway: the role of cAMP-response element binding (CREB) and modulator (CREMalpha and CREMtau2alpha) proteins." dans: Journal of molecular endocrinology, Vol. 34, Issue 1, pp. 1-17, 2005

Perry, Sklan, Soreq: "CREB regulates AChE-R-induced proliferation of human glioblastoma cells." dans: Neoplasia (New York, N.Y.), Vol. 6, Issue 3, pp. 279-86, 2004

Images

Détail du produit anti-CREB1 anticorps Détail du antigène CREB1 Information d'application Stockage References for anti-CREB1 antibody (ABIN358113) Haut de la page
Supplier Images
 image for anti-CAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody (ABIN358113) anti-CAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody
 image for anti-CAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody (ABIN358113) anti-CAMP Responsive Element Binding Protein 1 (CREB1) (pSer133) antibody (Image 2)