Aperçu des produits pour anti-MAP4K1 (MAP4K1) Anticorps

Full name:
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 Anticorps (MAP4K1)
Chez www.anticorps-enligne.fr sont 131 Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) Anticorps de 18 de différents fournisseurs disponibles. De plus, nous expédions MAP4K1 Protéines (6) et et beaucoup plus de produits pour cette protéine. Un total de 145 MAP4K1 produits sont actuellement listés.
Synonymes:
Hpk1, mHPK1
afficher tous les anticorps Gène GeneID UniProt
MAP4K1 292763  
MAP4K1 11184 Q92918
MAP4K1 26411 P70218

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anti-MAP4K1 Anticorps mieux référencés

  1. Human Polyclonal MAP4K1 Primary Antibody pour EIA - ABIN358386 : Hu, Qiu, Wang, Meyer, Tan: Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade. dans Genes & development 1996 (PubMed)
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  2. Human Polyclonal MAP4K1 Primary Antibody pour EIA - ABIN358384 : Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: Large-scale characterization of HeLa cell nuclear phosphoproteins. dans Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
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  3. Human Polyclonal MAP4K1 Primary Antibody pour IHC (p), WB - ABIN392502 : Sawasdikosol, Russo, Burakoff: Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription. dans Blood 2003 (PubMed)
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  4. Cow (Bovine) Polyclonal MAP4K1 Primary Antibody pour WB - ABIN2773872 : Brenner, Golks, Becker, Müller, Frey, Novak, Melamed, Kiefer, Krammer, Arnold: Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes. dans Blood 2007 (PubMed)

Plus d’anticorps contre MAP4K1 partenaires d’interaction

Human Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) interaction partners

  1. CUL7 (Montrer CUL7 Anticorps)/Fbxw8 (Montrer FBXW8 Anticorps) ubiquitin ligase-mediated HPK1 degradation revealed a direct link and novel role of CUL7 (Montrer CUL7 Anticorps)/Fbxw8 (Montrer FBXW8 Anticorps) ubiquitin ligase in the MAPK (Montrer MAPK1 Anticorps) pathway, which plays a critical role in cell proliferation and differentiation.

  2. HPK1 is critically involved in LFA-1 (Montrer ITGAL Anticorps)-mediated polymorphonuclear neutrophils trafficking during acute inflammation.

  3. results indicate that uncleaved HPK1 is a positive regulator of vitamin D-induced differentiation in acute myeloid leukemia (Montrer BCL11A Anticorps) cells, but the cleaved HPK1 fragment inhibits differentiation

  4. Pdcd4 (Montrer PDCD4 Anticorps) knockdown up-regulates MAP kinase (Montrer MAPK1 Anticorps) kinase kinase kinase 1 (MAP4K1) expression and increases phosphorylation of c-Jun (Montrer JUN Anticorps).

  5. QVD and 1,25D-induced differentiation was accompanied by increased signaling by Hematopoietic Progenitor Kinase 1(HPK1), and the expression of transcription factors known to be involved in monocytic differentiation was increased.

  6. HPK1 negatively regulates T cell activation by reducing the persistence of signaling microclusters.

  7. The purpose of the study was to investigate the potential contribution of HPK1, MEKK1 (Montrer MAP3K1 Anticorps), TAK1 (Montrer MAP3K7 Anticorps), p-MKK4 (Montrer MAP2K4 Anticorps) to the development of extramammary Paget disease

  8. The catalytic activity of a hematopoietic cell-restricted, Ste20-related S/TPK, HPK1, is positively regulated by exposure to physiological concentrations of PGE2. HPK1 is a negative regulator of PGE2-induced FOS gene transcription.

  9. PP4 (Montrer ANXA5 Anticorps) is a positive regulator for HPK1 and the HPK1-JNK (Montrer MAPK8 Anticorps) signaling pathway

  10. Full activation of HPK1 is dependent on autophosphorylation of threonine 165 and phosphorylation of serine 171, which is a target site for protein kinase D (PKD) in vitro.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 (MAP4K1) interaction partners

  1. Introduction of three 4-R-hydroxyproline residues stabilizes the SH3m-cortactin (Montrer CTTN Anticorps) binding of HPK1 peptide.

  2. a novel negative feedback regulation of BCR (Montrer BCR Anticorps) signaling by HPK1-mediated phosphorylation, ubiquitination, and subsequent degradation of the activated BLNK (Montrer BLNK Anticorps)

  3. HPK1 associates with SKAP1 (Montrer SKAP1 Anticorps) to negatively regulate Rap1 (Montrer TERF2IP Anticorps)-mediated B-lymphocyte (Montrer AKAP17A Anticorps) adhesion.

  4. HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion.

  5. Hpk1 supports apoptosis of T lymphocytes by inhibiting the antiapoptotic action of NF-kappaB (Montrer NFKB1 Anticorps) and inducing the proapoptotic activity of JNK (Montrer MAPK8 Anticorps).

  6. Mona/Gads (Montrer GRAP2 Anticorps) SH3C binding to hematopoietic progenitor kinase 1 (HPK1) combines an atypical SH3 binding motif, R/KXXK, with a classical PXXP motif embedded in a polyproline type II (PPII) helix

  7. suppression or activation of NFkappaB by HPK1 determines sensitivity to activation-induced cell death

  8. HPK1-C as a suppressor of antiapoptotic Bcl-2 (Montrer BCL2 Anticorps) proteins and provide a molecular basis for our understanding of CD95L (Montrer FASL Anticorps)-independent activation-induced cell death of lymphocytes.

  9. Our data reveal a novel role for HPK1 as a negative regulator of dendritic cell functions

MAP4K1 profil antigène

Antigen Summary

May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation.

Alternative names and synonyms associated with MAP4K1

  • mitogen activated protein kinase kinase kinase kinase 1 (Map4k1) anticorps
  • mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1) anticorps
  • mitogen-activated protein kinase kinase kinase kinase 1 (Map4k1) anticorps
  • Hpk1 anticorps
  • mHPK1 anticorps

Protein level used designations for MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1 , MAPK/ERK kinase kinase kinase 1 , MEK kinase kinase 1 , MEKKK 1 , hematopoietic progenitor kinase 1 , HPK , mitogen activated protein kinase kinase kinase kinase 1

GENE ID SPECIES
292763 Rattus norvegicus
522002 Bos taurus
11184 Homo sapiens
26411 Mus musculus
484527 Canis lupus familiaris
100516374 Sus scrofa
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