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Aperçu des produits pour anti-PKB (PKB) Anticorps

Full name:
anti-Protein Kinase B Anticorps (PKB)
Chez sont 0 Protein Kinase B (PKB) Anticorps de de différents fournisseurs disponibles. De plus, nous expédions PKB Kits (22) et beaucoup plus de produits pour cette protéine. Un total de 22 PKB produits sont actuellement listés.
afficher tous les anticorps Gène GeneID UniProt
Anti-Humain PKB PKB 2185 Q14289
Anti-Souris PKB PKB 11651 P31750
Anti-Rat PKB PKB 24185 P47196

Afficher tous les synonymes

Plus d’anticorps contre PKB partenaires d’interaction

Human Protein Kinase B (PKB) interaction partners

  1. Studies suggest that PYK2 (Montrer PTK2B Anticorps) is a common downstream effector of ErbB (Montrer EGFR Anticorps) and IL8 (Montrer IL8 Anticorps) receptors, and that PYK2 (Montrer PTK2B Anticorps) integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  2. Pyk2 (Montrer PTK2B Anticorps) is a key downstream signaling molecules of CCR7 (Montrer CCR7 Anticorps) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  3. Phosphoproteomic analysis identifies FAK2 (Montrer PTK2B Anticorps) as a potential therapeutic target for tamoxifen resistance in breast cancer.

  4. Pyk2 (Montrer PTK2B Anticorps)-focal adhesion targeting domain interacts with and binds to leupaxin (Montrer LPXN Anticorps).

  5. Src (Montrer SRC Anticorps) has a role in priming Pyk2 (Montrer PTK2B Anticorps) (but not FAK (Montrer PTK2 Anticorps)) phosphorylation and subsequent activation downstream of integrins

  6. Data strongly suggest that chemokine-stimulated associations between Vav1, SLP-76, and ADAP facilitate Rac1 activation and alpha4beta1-mediated adhesion, whereas Pyk2 opposes this adhesion by limiting Rac1 activation.

  7. FAK (Montrer PTK2 Anticorps) and PYK2 (Montrer PTK2B Anticorps) functioned redundantly to promote the Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) pathway by phosphorylating GSK3beta (Montrer GSK3b Anticorps)(Y216) to reinforce pathway output-beta-catenin (Montrer CTNNB1 Anticorps) accumulation and intestinal tumorigenesis.

  8. This study identified Pyk2 (Montrer PTK2B Anticorps) as a cellular component required for the intracellular trafficking of HPV16 during infection.

  9. These results suggest that melatonin exerts anti-migratory and anti-invasive effects on glioma cells in response to hypoxia via reactive oxygen species-alphavbeta3 integrin-FAK (Montrer PTK2 Anticorps)/Pyk2 (Montrer PTK2B Anticorps) signaling pathways.

  10. data suggest a novel role for FAK (Montrer PTK2 Anticorps) in GPVI (Montrer GP6 Anticorps)-dependent ROS (Montrer ROS1 Anticorps) formation and platelet activation and elucidate a proximal signaling role for FAK (Montrer PTK2 Anticorps) within the GPVI (Montrer GP6 Anticorps) pathway.

Mouse (Murine) Protein Kinase B (PKB) interaction partners

  1. Results suggest a role of ST6GalNAc I (Montrer ST6GALNAC1 Anticorps) in promoting the growth and invasion of hepatocarcinoma cells through regulating PI3K/AKT (Montrer AKT1 Anticorps)/NF-kappa B (Montrer NFKB1 Anticorps) signaling, and ST6GalNAc I (Montrer ST6GALNAC1 Anticorps) might be a marker for the prognosis and therapy of hepatocarcinoma.

  2. The data indicate that the balanced activities of two related serine/threonine kinases, AKT (Montrer AKT1 Anticorps) and SGK1 (Montrer SGK1 Anticorps), critically govern the embryo implantation process.

  3. These results suggest that DDI may improve insulin (Montrer INS Anticorps) sensitivity through the activation of Akt (Montrer AKT1 Anticorps) signaling, which leads to enhanced glucose uptake.

  4. observations revealed that the alteration of PKB-GSK-3beta axis, Plk-1, and Aurora kinase-A expressions in HSPC compartment due to DNA damage response was associated with the proliferative impairment and apoptosis during aplastic anemia.

  5. A20 (Montrer TNFAIP3 Anticorps) reduces lipid storage and inflammation in hypertrophic adipocytes via p38 (Montrer CRK Anticorps) and Akt (Montrer AKT1 Anticorps) signaling.

  6. the mTORC2 (Montrer CRTC2 Anticorps)/Akt (Montrer AKT1 Anticorps)/NFkappaB pathway-mediated activation of TRPC6 (Montrer TRPC6 Anticorps) participates in adriamycin-induced podocyte apoptosis.

  7. Ambient fine particulate matter-induced myocarditis is mediated by EGFR (Montrer EGFR Anticorps)/Akt (Montrer AKT1 Anticorps) signaling and overexpression of NLRP3 (Montrer NLRP3 Anticorps) and NLRP12 (Montrer NLRP12 Anticorps).

  8. GSK3b (Montrer GSK3b Anticorps) may up-regulate BK channels, an effect disrupted by lithium or additional expression of AKT (Montrer AKT1 Anticorps) and possibly participating in the regulation of cell volume and excitability.

  9. Akt1 regulates cell division and F-actin rearrangement in mouse fertilized eggs.

  10. The results suggest that KCa3.1 (Montrer KCNN4 Anticorps) activation contributes to dysfunctional tubular autophagy in diabetic nephropathy through PI3K/Akt (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps) signaling pathways.

Pig (Porcine) Protein Kinase B (PKB) interaction partners

  1. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 (Montrer AKT1 Anticorps) could positively regulate lactose synthesis.

  2. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  3. Host PI3K and Akt1 (Montrer AKT1 Anticorps) play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  4. Activity of AKT (Montrer AKT1 Anticorps) is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  5. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  6. findings show that megalin (Montrer LRP2 Anticorps) is the sensor that determines whether cells will be protected or injured by albumin (Montrer ALB Anticorps); it binds protein kinase B (PKB (Montrer AKT1 Anticorps)) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB (Montrer AKT1 Anticorps) in the luminal plasma membrane [

  7. protein kinase B (PKB/Akt (Montrer AKT1 Anticorps))was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  8. Akt (Montrer AKT1 Anticorps) signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

  9. in VSMCs exposed to hyperglycemia, IGF-I (Montrer IGF1 Anticorps) stimulation of Shc (Montrer SHC1 Anticorps) facilitates the transfer of Grb2 (Montrer GRB2 Anticorps) to p85 (Montrer ARHGEF7 Anticorps) resulting in enhanced PI3K activation and AKT (Montrer AKT1 Anticorps) phosphorylation leading to enhanced cell proliferation and migration

  10. There was no correlation of infarct size with expression or phosphorylation of AKT (Montrer AKT1 Anticorps) in ischemic postconditioning.

Goat Protein Kinase B (PKB) interaction partners

  1. Exogenous AKT (Montrer AKT1 Anticorps) was transcribed, and AKT (Montrer AKT1 Anticorps) was overexpressed, inducing the phosphorylation of p70S6K (Montrer RPS6KB1 Anticorps) (Thr389) and 4E-BP1 (Montrer EIF4EBP1 Anticorps) (Thr37/46) in goat fetal fibroblasts.

Cow (Bovine) Protein Kinase B (PKB) interaction partners

  1. These results demonstrate that activation of AKT (Montrer AKT1 Anticorps) is required for gonadotropin regulation of CTNNB1 (Montrer CTNNB1 Anticorps) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (Montrer CAV1 Anticorps) scaffolding domain residue phenylalanine 92 modulates Akt (Montrer AKT1 Anticorps) signaling

  3. TG2 (Montrer TGM2 Anticorps) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT (Montrer AKT1 Anticorps) signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt (Montrer AKT1 Anticorps) activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (Montrer GSK3b Anticorps), and NF-kappaB (Montrer NFKB1 Anticorps).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (Montrer NOX1 Anticorps), reactive oxygen species, and PI3-kinase (Montrer PIK3CA Anticorps) in stimulated NO release.

  6. PI3K/Akt (Montrer AKT1 Anticorps) and p53 (Montrer TP53 Anticorps) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (Montrer AKT1 Anticorps), mTOR (Montrer FRAP1 Anticorps), p70S6K (Montrer RPS6KB1 Anticorps), and ERK1/2 (Montrer MAPK1/3 Anticorps).

  8. Gab1 (Montrer GAB1 Anticorps) tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B (Montrer AKT1 Anticorps) and endothelial nitric-oxide synthase (Montrer NOS3 Anticorps) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (Montrer NOS3 Anticorps) phosphorylation and suppresses tumor necrosis factor alpha (Montrer TNF Anticorps)-induced endothelial cell apoptosis by activating AKT1 (Montrer AKT1 Anticorps).

  10. prostaglandin F2alpha phosphorylates TSC2 (Montrer TSC2 Anticorps) and activates mTOR (Montrer FRAP1 Anticorps) and ribosomal protein S6 (Montrer RPS6 Anticorps) kinase (Montrer RPS6KB1 Anticorps) signaling in an AKT (Montrer AKT1 Anticorps)-independent manner

PKB profil antigène

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PKB

  • protein tyrosine kinase 2 beta (PTK2B) anticorps
  • thymoma viral proto-oncogene 1 (Akt1) anticorps
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) anticorps
  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) anticorps
  • v-akt murine thymoma viral oncogene homolog 2 (AKT2) anticorps
  • AKT anticorps
  • CADTK anticorps
  • CAKB anticorps
  • FADK2 anticorps
  • FAK2 anticorps
  • PKB anticorps
  • PKB/Akt anticorps
  • PKBalpha anticorps
  • PTK anticorps
  • PYK2 anticorps
  • Rac anticorps
  • RAFTK anticorps

Protein level used designations for anti-Protein Kinase B (PKB) Anticorps

CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , AKT1 kinase , PKB alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1 , RAC-beta serine/threonine-protein kinase

2185 Homo sapiens
11651 Mus musculus
24185 Rattus norvegicus
100126861 Sus scrofa
100860904 Capra hircus
280991 Bos taurus
100294652 Ovis aries
449021 Canis lupus familiaris
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