You are viewing an incomplete version of our website. Please click to reload the website as full version.

Aperçu des produits pour anti-PKB (PKB) Anticorps

Full name:
anti-Protein Kinase B Anticorps (PKB)
Chez www.anticorps-enligne.fr sont 8 Protein Kinase B (PKB) Anticorps de 5 de différents fournisseurs disponibles. De plus, nous expédions PKB Kits (22) et beaucoup plus de produits pour cette protéine. Un total de 30 PKB produits sont actuellement listés.
Synonymes:
AKT, CADTK, CAKB, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, PYK2, Rac, RAFTK

Réactivités les plus populaires pour anti-PKB (PKB) Anticorps

Sélectionnez vos espèces et l'application

anti-Human PKB Anticorps:

anti-Mouse (Murine) PKB Anticorps:

anti-Rat (Rattus) PKB Anticorps:

Tous anti-PKB Anticorps disponible

Vous arrivez à notre recherche pré-filtrée.

anti-PKB Anticorps mieux référencés

  1. Mouse (Murine) Polyclonal PKB Primary Antibody pour IHC, WB - ABIN350718 : Anai, Shojima, Katagiri, Ogihara, Sakoda, Onishi, Ono, Fujishiro, Fukushima, Horike, Viana, Kikuchi, Noguchi, Takahashi, Takata, Oka, Uchijima, Kurihara, Asano: A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis. dans The Journal of biological chemistry 2005 (PubMed)
    Show all 5 references for ABIN350718

Plus d’anticorps contre PKB partenaires d’interaction

Human Protein Kinase B (PKB) interaction partners

  1. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin, a process in part mediated through the PI3-kinase (Montrer PIK3CA Anticorps)-Akt/PKB (Montrer AKT1 Anticorps) cell survival pathway. These results provide further rationale for clinical investigation of relaxin as a potential therapeutic in preeclampsia.

  2. PTK2B polymorphism (rs28834970) could modify the risk of late-onset Alzheimer's disease (LOAD), and PTK2B polymorphism (rs28834970) and APOE may interact to increase LOAD risk in a Han Chinese population.

  3. Studies suggest that PYK2 (Montrer PTK2B Anticorps) is a common downstream effector of ErbB (Montrer EGFR Anticorps) and IL8 (Montrer IL8 Anticorps) receptors, and that PYK2 (Montrer PTK2B Anticorps) integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  4. Pyk2 (Montrer PTK2B Anticorps) is a key downstream signaling molecules of CCR7 (Montrer CCR7 Anticorps) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  5. Phosphoproteomic analysis identifies FAK2 (Montrer PTK2B Anticorps) as a potential therapeutic target for tamoxifen resistance in breast cancer.

  6. Pyk2 (Montrer PTK2B Anticorps)-focal adhesion targeting domain interacts with and binds to leupaxin (Montrer LPXN Anticorps).

  7. Src (Montrer SRC Anticorps) has a role in priming Pyk2 (Montrer PTK2B Anticorps) (but not FAK (Montrer PTK2 Anticorps)) phosphorylation and subsequent activation downstream of integrins

  8. Data strongly suggest that chemokine-stimulated associations between Vav1, SLP-76, and ADAP facilitate Rac1 activation and alpha4beta1-mediated adhesion, whereas Pyk2 opposes this adhesion by limiting Rac1 activation.

  9. FAK (Montrer PTK2 Anticorps) and PYK2 (Montrer PTK2B Anticorps) functioned redundantly to promote the Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) pathway by phosphorylating GSK3beta (Montrer GSK3b Anticorps)(Y216) to reinforce pathway output-beta-catenin (Montrer CTNNB1 Anticorps) accumulation and intestinal tumorigenesis.

  10. This study identified Pyk2 (Montrer PTK2B Anticorps) as a cellular component required for the intracellular trafficking of HPV16 during infection.

Mouse (Murine) Protein Kinase B (PKB) interaction partners

  1. A cell-culture study using an inhibitor of estrogen receptors and an in vivo experiment with ovariectomized mice suggested that the estrogenic activity of 8-PN contributed to recovery from disuse muscle atrophy through activation of an Akt (Montrer AKT1 Anticorps) phosphorylation pathway. These data strongly suggest that 8-PN is a naturally occurring compound that could be used as a nutritional supplement to aid recovery from disuse muscle atroph

  2. Analysis of the successful model also elucidates two dynamical motifs: neutralization of a negative regulator, which characterizes how Akt (Montrer AKT1 Anticorps) indirectly activates mTORC1, and seesaw enzyme regulation, which describes how activated and inhibited states of mTORC1 are controlled in concert to produce a nonlinear, ultrasensitive response

  3. Data show that Akt (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps) and MAPK (Montrer MAPK1 Anticorps) pathways were activated in ovine pulmonary adenocarcinoma (OPA) lung and envelope (Env (Montrer ERVW-1 Anticorps)) of Jaagsiekte sheep retrovirus (JSRV) transfected NIH 3T3 cells.

  4. Results suggest that SC79 compound activates Akt (Montrer AKT1 Anticorps)-Nrf2 (Montrer NFE2L2 Anticorps) signaling to protect osteoblasts from dexamethasone (Dex).

  5. In conclusion, we have identified that ARL15 acts as an insulin (Montrer INS Anticorps)-sensitizing effector molecule to upregulate the phosphorylation of members of the canonical IR/IRS1 (Montrer IRS1 Anticorps)/PDPK1 (Montrer PDPK1 Anticorps)/AKT (Montrer AKT1 Anticorps) insulin (Montrer INS Anticorps) pathway by interacting with its GAP ASAP2 (Montrer ASAP2 Anticorps) and activating PDPK1 (Montrer PDPK1 Anticorps). This research may provide new insights into GTPase (Montrer RACGAP1 Anticorps)-mediated insulin (Montrer INS Anticorps) signalling regulation and facilitate the development of new pharmacotherapeutic targets for insulin (Montrer INS Anticorps) sensitizati

  6. Taken together, our findings imply that KLF15 possesses potential anti-hypertrophic and anti-fibrotic functions, possibly via regulation of cell death pathways and the inhibition of Akt/mTOR axis. KLF15 may constitute an efficient candidate drug for the treatment of heart failure and other cardiovascular diseases.

  7. Menin (Montrer MEN1 Anticorps) binds on the promoter of Inhbb (Montrer INHBB Anticorps) gene where it favours the recruitment of Ezh2 (Montrer EZH2 Anticorps) via an indirect mechanism involving Akt (Montrer AKT1 Anticorps)-phosphorylation.

  8. A role of AKT (Montrer AKT1 Anticorps) in the regulatory T cell differentiation process. TGF-beta (Montrer TGFB1 Anticorps) induces the phosphorylation of Akt (Montrer AKT1 Anticorps) in CD4 (Montrer CD4 Anticorps)+ T cells.

  9. 4-PBA reverses autophagic dysfunction and improves insulin (Montrer INS Anticorps) sensitivity in adipose tissue of obese mice via Akt (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps) signaling partly, which could be regarded as novel opportunities for treatment of insulin (Montrer INS Anticorps) resistance.

  10. These studies reveal a novel mechanism in which CYP2J2 (Montrer CYP2J2 Anticorps) and epoxyeicosatrienoic acids enhanced Akt1 (Montrer AKT1 Anticorps) nuclear translocation through interaction with AMPKalpha2beta2gamma1 and protect against cardiac hypertrophy.

Pig (Porcine) Protein Kinase B (PKB) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (Montrer AKT1 Anticorps)-mTOR (Montrer FRAP1 Anticorps)-FOXO1 (Montrer FOXO1 Anticorps) signaling and suppressing the activation of TLR4 (Montrer TLR4 Anticorps) and/or NOD2 (Montrer NOD2 Anticorps) signaling pathways.

  2. Data show that homocysteine (Hcy) can ameliorate the endothelium-independent hypoxic coronary vasoconstriction, in which the inhibition of PI3K/Akt (Montrer AKT1 Anticorps) signaling pathway may be involved.

  3. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 (Montrer AKT1 Anticorps) could positively regulate lactose synthesis.

  4. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  5. Host PI3K and Akt1 (Montrer AKT1 Anticorps) play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  6. Activity of AKT (Montrer AKT1 Anticorps) is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  7. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  8. findings show that megalin (Montrer LRP2 Anticorps) is the sensor that determines whether cells will be protected or injured by albumin (Montrer ALB Anticorps); it binds protein kinase B (PKB (Montrer AKT1 Anticorps)) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB (Montrer AKT1 Anticorps) in the luminal plasma membrane [

  9. protein kinase B (PKB/Akt (Montrer AKT1 Anticorps))was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  10. Akt (Montrer AKT1 Anticorps) signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

Goat Protein Kinase B (PKB) interaction partners

  1. Exogenous AKT (Montrer AKT1 Anticorps) was transcribed, and AKT (Montrer AKT1 Anticorps) was overexpressed, inducing the phosphorylation of p70S6K (Montrer RPS6KB1 Anticorps) (Thr389) and 4E-BP1 (Montrer EIF4EBP1 Anticorps) (Thr37/46) in goat fetal fibroblasts.

Cow (Bovine) Protein Kinase B (PKB) interaction partners

  1. These results demonstrate that activation of AKT (Montrer AKT1 Anticorps) is required for gonadotropin regulation of CTNNB1 (Montrer CTNNB1 Anticorps) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (Montrer CAV1 Anticorps) scaffolding domain residue phenylalanine 92 modulates Akt (Montrer AKT1 Anticorps) signaling

  3. TG2 (Montrer TGM2 Anticorps) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT (Montrer AKT1 Anticorps) signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt (Montrer AKT1 Anticorps) activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (Montrer GSK3b Anticorps), and NF-kappaB (Montrer NFKB1 Anticorps).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (Montrer NOX1 Anticorps), reactive oxygen species, and PI3-kinase (Montrer PIK3CA Anticorps) in stimulated NO release.

  6. PI3K/Akt (Montrer AKT1 Anticorps) and p53 (Montrer TP53 Anticorps) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (Montrer AKT1 Anticorps), mTOR (Montrer FRAP1 Anticorps), p70S6K (Montrer RPS6KB1 Anticorps), and ERK1/2 (Montrer MAPK1/3 Anticorps).

  8. Gab1 (Montrer GAB1 Anticorps) tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B (Montrer AKT1 Anticorps) and endothelial nitric-oxide synthase (Montrer NOS3 Anticorps) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (Montrer NOS3 Anticorps) phosphorylation and suppresses tumor necrosis factor alpha (Montrer TNF Anticorps)-induced endothelial cell apoptosis by activating AKT1 (Montrer AKT1 Anticorps).

  10. prostaglandin F2alpha phosphorylates TSC2 (Montrer TSC2 Anticorps) and activates mTOR (Montrer FRAP1 Anticorps) and ribosomal protein S6 (Montrer RPS6 Anticorps) kinase (Montrer RPS6KB1 Anticorps) signaling in an AKT (Montrer AKT1 Anticorps)-independent manner

PKB profil antigène

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PKB

  • protein tyrosine kinase 2 beta (PTK2B) anticorps
  • thymoma viral proto-oncogene 1 (Akt1) anticorps
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) anticorps
  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) anticorps
  • v-akt murine thymoma viral oncogene homolog 2 (AKT2) anticorps
  • AKT anticorps
  • CADTK anticorps
  • CAKB anticorps
  • FADK2 anticorps
  • FAK2 anticorps
  • PKB anticorps
  • PKB/Akt anticorps
  • PKBalpha anticorps
  • PTK anticorps
  • PYK2 anticorps
  • Rac anticorps
  • RAFTK anticorps

Protein level used designations for anti-Protein Kinase B (PKB) Anticorps

CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , AKT1 kinase , PKB alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1 , RAC-beta serine/threonine-protein kinase

GENE ID SPECIES
2185 Homo sapiens
11651 Mus musculus
24185 Rattus norvegicus
100126861 Sus scrofa
100860904 Capra hircus
280991 Bos taurus
100294652 Ovis aries
449021 Canis lupus familiaris
Fournisseurs de qualité sélectionnés pour anti-PKB (PKB) Anticorps
Avez-vous cherché autre chose?