Aperçu des produits pour anti-PTEN (PTEN) Anticorps

Full name:
anti-Phosphatase and Tensin Homolog Anticorps (PTEN)
Chez www.anticorps-enligne.fr sont 0 Phosphatase and Tensin Homolog (PTEN) Anticorps de de différents fournisseurs disponibles. Un total de 0 PTEN produits sont actuellement listés.
Synonymes:
10q23del, 2310035O07Rik, A130070J02Rik, AI463227, B430203M17Rik, BZS, CWS1, DEC, GLM2, MHAM, Mmac, MMAC1, PTEN1, PTENP1, TEP1
afficher tous les anticorps Gène GeneID UniProt
Anti-Souris PTEN PTEN 19211 O08586
Anti-Rat PTEN PTEN 50557  
Anti-Humain PTEN PTEN 5728 P60484

Afficher tous les synonymes

Plus d’anticorps contre PTEN partenaires d’interaction

Mouse (Murine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. these results demonstrate that miR (Montrer MLXIP Anticorps)-26b might participate in regulating adipogenic differentiation in 3T3-L1 cells by inhibiting the PTEN expression, further highlighting the importance of miRNA in adipogenesis.

  2. Studies indicate complex PTEN-cooperating tumor suppressor networks in different cancer types, with potential clinical implications.

  3. Studies indicate that progesterone receptor (Montrer PGR Anticorps) transgenic (Pgrcre/+) mitogen inducible gene 6 (Mig (Montrer CXCL9 Anticorps)-6over) phosphatase and tensin homolog protein (Ptenf/f) knockout mice exhibited an increase of phospho-ERK1/2 (Montrer MAPK1/3 Anticorps) and its target genes.

  4. Studies indicate that the Pten+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten is a key regulatory player in the PI3K/PTEN/AKT (Montrer AKT1 Anticorps) pathway.

  5. Using an extensive collection of novel murine cell lines we have identified distinct roles for Kras and Pten on MUC1 (Montrer MUC1 Anticorps) and EMT (Montrer ITK Anticorps) in vivo and in vitro. The data has implications for future design of combination therapies targeting Kras mutations, Pten deletions and MUC1 (Montrer MUC1 Anticorps) vaccines.

  6. novel role for PTEN during infection and identify regulation of the PI3K pathway, a mechanism previously shown to silence autoreactive B cells, as a key physiological target to control antibody responses.

  7. This study demonstrated Pten Regulates Retinal Amacrine Cell Number by Modulating Akt (Montrer AKT1 Anticorps), Tgfbeta (Montrer TGFB1 Anticorps), and Erk (Montrer EPHB2 Anticorps) Signaling in mice.

  8. Tregs ameliorated ICH (Montrer ACE Anticorps)-induced inflammatory injury by modulating microglia/macrophage polarization toward the M2 phenotype through the IL-10 (Montrer IL10 Anticorps)/GSK3beta (Montrer GSK3b Anticorps)/PTEN axis

  9. Data show that macrophage M2 polarization was mediated through PTEN/PI3k/AKT (Montrer AKT1 Anticorps) pathway activation.

  10. this study shows this study shows that infection-induced miR (Montrer MLXIP Anticorps)-21 promotes severe, steroid-insensitive allergic airway disease by reducing PTEN expression

Human Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN rs701848 and AKT1 (Montrer AKT1 Anticorps) rs2494752 polymorphisms might be a candidate pharmacogenomic factor to assess the susceptibility of and response and prognosis prediction for interindividualized CE(A)F chemotherapy in breast cancer patients.

  2. Meta-analysis demonstrates that PTEN loss is of particular importance for predicting breast cancer aggressiveness and poor prognosis. PTEN is a potential drug target for the development of individualized treatment in breast cancer patients.

  3. PTENp1 was aberrantly expressed in oral squamous cell carcinoma. There was a positive correlation between the expression levels of PTENp1 and PTEN. Further, we showed that PTENp1 acted as a competing endogenous RNA that protects PTEN transcripts from being inhibited by miR (Montrer MLXIP Anticorps)-21, and consequently inhibited proliferation and colony formation and triggered S-G2 (Montrer STRN3 Anticorps)/M cell cycle arrest through the AKT (Montrer AKT1 Anticorps) pathway.

  4. Results indicate that p110alpha (Montrer PIK3CA Anticorps) primarily mediates PI3K (Montrer PIK3CA Anticorps)/AKT (Montrer AKT1 Anticorps) signaling in HER2 (Montrer ERBB2 Anticorps)+ PTEN deficient breast tumors whereas p110beta conditionally mediates HER2 (Montrer ERBB2 Anticorps)/PI3K (Montrer PIK3CA Anticorps) signaling in the absence of p110alpha (Montrer PIK3CA Anticorps).

  5. Her-2 (Montrer ERBB2 Anticorps)-positive metastatic breast cancers, PTEN positivity was significantly associated with progressive disease, but not with PFS or OS

  6. Findings indicate that Epstein-Barr virus(EBV)-encoded latent membrane protein 1 (LMP1 (Montrer PDLIM7 Anticorps)), PI3K (Montrer PIK3CA Anticorps)/AKT (Montrer AKT1 Anticorps), miR (Montrer MLXIP Anticorps)-21 and PTEN constitute a positive feedback loop and have a key role in LMP1 (Montrer PDLIM7 Anticorps)-induced cancer stem cells (CSCs) in nasopharyngeal carcinoma (NPC (Montrer NPC1 Anticorps)).

  7. Coexpression of SALL4 (Montrer SALL4 Anticorps) with HDAC1 (Montrer HDAC1 Anticorps) and/or HDAC2 (Montrer HDAC2 Anticorps) was associated with PTEN underexpression and a poor prognosis in hepatocellular carcinoma.

  8. PTEN promoter methylation is an independent predictor for impaired survival with malignant melanoma.

  9. Studies indicate that frequently altered genes in type I carcinomas are TP53, K-Ras, PTEN, and ss-catenin.

  10. Study provide evidence that PTEN deletion and TMPRSS2 (Montrer TMPRSS2 Anticorps)-ERG (Montrer ERG Anticorps) gene fusion were mutually exclusive in patients with prostate neoplasm. TMPRSS2 (Montrer TMPRSS2 Anticorps)-ERG (Montrer ERG Anticorps) gene fusion was rare compared to peripheral zone tumors and to PTEN inactivation in T1a (Montrer PDPN Anticorps) transition zone tumors.

Pig (Porcine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN, FOXO3A (Montrer FOXO3 Anticorps) and PKB (Montrer AKT1 Anticorps) were expressed in a stage- and cell-specific manner during ovarian follicle formation and development in the fetal and neonatal pig.

Cow (Bovine) Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. the miR-17-92 cluster is involved in granulosa cell proliferation and differentiation by coordinately targeting the PTEN and BMPR2 (Montrer BMPR2 Anticorps) genes.

  2. miR (Montrer MYLIP Anticorps)-26b participates in the inflammatory response of LPS (Montrer IRF6 Anticorps)-stimulated bAMs by modulating the NF-kappaB (Montrer NFKB1 Anticorps) pathway through targeting PTEN.

  3. Pten expression levels in the mammary glands of dairy cows, was investigated.

  4. These studies identify a key role for PTEN in the modulation of lipid mediators involved in adenosine diphosphate receptor-regulated endothelial signaling pathways involving eNOS (Montrer NOS3 Anticorps) activation in vascular endothelial cells.

  5. Overexpressing PTEN enhanced fatty acid oxidation and assembly and secretion of VLDL in cultured hepatocytes.

  6. Inhibition of PTEN activity had no effect on cyclic strain-mediated cell proliferation but inhibited cyclic strain-mediated suppression of apoptosis

Xenopus laevis Phosphatase and Tensin Homolog (PTEN) interaction partners

  1. PTEN plays an important role in multicilia formation and cilia disassembly by controlling the phosphorylation of Dishevelled (Montrer DVL2 Anticorps).

  2. PTEN negatively regulates growth cone phosphatidylinositol 3,4,5-trisphosphate levels and mediates chemorepulsion, whereas chemoattraction is PTEN-independent.

  3. PTEN-dependent slowing of axonal growth enables the establishment of stable nerve-muscle contacts that develop into neuromuscular junctions.

PTEN profil antigène

Antigen Summary

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT\\/PKB signaling pathway.

Alternative names and synonyms associated with PTEN

  • phosphatase and tensin homolog (Pten) anticorps
  • phosphatase and tensin homolog (PTEN) anticorps
  • phosphatase and tensin homolog (pten) anticorps
  • 10q23del anticorps
  • 2310035O07Rik anticorps
  • A130070J02Rik anticorps
  • AI463227 anticorps
  • B430203M17Rik anticorps
  • BZS anticorps
  • CWS1 anticorps
  • DEC anticorps
  • GLM2 anticorps
  • MHAM anticorps
  • Mmac anticorps
  • MMAC1 anticorps
  • PTEN1 anticorps
  • PTENP1 anticorps
  • TEP1 anticorps

Protein level used designations for PTEN

mutated in multiple advanced cancers 1 , phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN , protein tyrosine phosphatase and tensin-like protein , phosphatase and tensin homolog deleted on chromosome ten , phosphatase and tensin homolog (mutated in multiple advanced cancers 1) , MMAC1 phosphatase and tensin homolog deleted on chromosome 10 , phosphatase and tensin-like protein , homolog of human mutated in multiple advanced cancers , protein/lipid phosphatase Pten

GENE ID SPECIES
19211 Mus musculus
50557 Rattus norvegicus
423675 Gallus gallus
5728 Homo sapiens
403832 Canis lupus familiaris
100156264 Sus scrofa
540786 Bos taurus
399142 Xenopus laevis
Avez-vous cherché autre chose?