Aperçu des produits pour PCNA (PCNA) Kits ELISA

Full name:
Proliferating Cell Nuclear Antigen Kits ELISA (PCNA)
Chez www.anticorps-enligne.fr sont 53 Proliferating Cell Nuclear Antigen (PCNA) Kits ELISA de 14 de différents fournisseurs disponibles. De plus, nous expédions PCNA Anticorps (717) et PCNA Protéines (38) et beaucoup plus de produits pour cette protéine. Un total de 825 PCNA produits sont actuellement listés.
Synonymes:
53/13, AO090003000846, cb16, CG9193, Dmel\\CG9193, DmPCNA, dPCNA, fb36g03, l(2)02448, l(2)56F, l(2)56Fa, l(2)s1534, Mus209, pcna, pcna-A, Pcna/cyclin, PCNA/mus209, PCNAR, wu:fa28e03, wu:fb36g03

Plus Kits ELISA pour PCNA partenaires d'interaction

Fruit Fly (Drosophila melanogaster) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. Results show that regulation of e2f1 and PCNA by DREF in vivo is complex and the regulation mechanism may differ with the tissue and/or positions in the tissue.

  2. crystal of DmPCNA diffracted to 2.0 A resolution and belonged to space group H3, with unit-cell parameters a = b = 151.16, c = 38.28 A

  3. We observed that SUUR chromosomal localization changed along with PCNA pattern and these proteins largely co-localized during the late S-phase in salivary glands.

  4. E2F (Montrer E2F2 Kits ELISA) regulation of PCNA is dispensable for viability, but is nonetheless important for normal Drosophila development.

  5. A Q123V mutation dramaticly enhances the abilities of Drosophila PCNA to stimulate calf thymus pol delta (Montrer POLD1 Kits ELISA). Replacing the entire interdomain connector loop AA 119-133 with the corresponding residues from human PCNA results in additional enhancement.

Tomato (Solanum lycopersicum) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. tomato DDI2 gene is required for UV-induced DNA damage repair and plant tolerance to UV stress. [DDI2]

Human Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. Multiple studies provide evidence that PCNA lies at the center of the faithful duplication of eukaryotic genomes and therefore genome integrity. [review]

  2. Human CTF18-RFC clamp-loader complexed with non-synthesising POLE efficiently loads the PCNA sliding clamp.

  3. Results suggest that the UNG2 N-terminus may serve as a flexible scaffold to tether PCNA and RPA at the replication fork, and that post-translational modifications on the UNG2 N-terminus disrupt formation of the PCNA-UNG2-RPA protein complex.

  4. ECRG2 (Montrer SPINK7 Kits ELISA) in combination with cisplatin (DDP (Montrer TIMM8A Kits ELISA)) can inhibit viability and induce apoptosis in esophageal cancer DDP (Montrer TIMM8A Kits ELISA)-resistant cells, possibly via upregulation of p53 (Montrer TP53 Kits ELISA) expression and downregulation of PCNA expression.

  5. Reduced affinity of PCNA(S228I) for specific clients causes subtle cellular defects in undamaged cells which likely contribute to the etiology of PCNA-associated DNA repair disorder (PARD). Analysis of the binding between PCNA and PCNA-interacting proteins (PIPs (Montrer GPRASP1 Kits ELISA)) shows that the S228I change dramatically impairs the majority of these interactions, including that of Cdt1 (Montrer CDT1 Kits ELISA), DNMT1 (Montrer DNMT1 Kits ELISA), PolD3(p66 (Montrer POLD3 Kits ELISA)) and PolD4(p12 (Montrer POLD4 Kits ELISA)).

  6. Data suggest that, during human DNA replication, restricting PCNA (proliferating cell nuclear antigen) to the vicinity of its DNA target site is important; PCNA can be maintained at or near primer/template junctions during DNA synthesis by RPA (Montrer RPA1 Kits ELISA) (replication protein A) or SSB (single-stranded DNA-binding protein (Montrer RPA1 Kits ELISA)); here, the SSB used was from Escherichia coli.

  7. Studies demonstrated that POLH (Montrer POLH Kits ELISA) interaction with PCNA plays an indispensable role in the recruitment of pol-eta to UV-induced cyclobutane pyrimidine dimers site to carry out translesion synthesis (TLS (Montrer FUS Kits ELISA)), and the dissociation of pol-eta from PCNA after TLS (Montrer FUS Kits ELISA) is essential for maintaining high fidelity DNA replication.

  8. PCNA is a substrate of the HSV-1 deubiquitinase UL36USP, which has previously been shown to be involved mainly in virus uptake and maturation

  9. Disruption of PCNA-lamins A/C interactions by prelamin A induces DNA replication fork stalling

  10. PCNA plays a critical role in preventing CAG repeat (Montrer CELF3 Kits ELISA) expansions by modulating the structures of dynamic DNA via cooperation with base excision repair enzymes.

Mouse (Murine) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. work reveals that simulated microgravity promotes the apoptotic response through a combined modulation of the Uev1A/TICAM/TRAF (Montrer TRAF1 Kits ELISA)/NF-kappaB (Montrer NFKB1 Kits ELISA)-regulated apoptosis and the p53 (Montrer TP53 Kits ELISA)/PCNA- and ATM (Montrer ATM Kits ELISA)/ATR (Montrer ATR Kits ELISA)-Chk1 (Montrer CHEK1 Kits ELISA)/2-controlled DNA-damage response pathways.

  2. REV1 promote PCNA monoubiquitylation after UV radiation through interacting with ubiquitylated RAD18 (Montrer RAD18 Kits ELISA).

  3. PCNA was mainly localized in decidual-stromal cells.

  4. Luteolin may inhibit tumor angiogenesis and tumor cell proliferation by down-regulation of LFA- 3 and PCNA and up-regulation of ICAM-1 (Montrer ICAM1 Kits ELISA) in tumor tissue of tumor-bearing mice, thereby achieving its anti-tumor effect.

  5. Data suggest Usp1 (ubiquitin specific peptidase 1 (Montrer USP1 Kits ELISA)) down-regulation by autocleavage is critical for Usp1 (Montrer USP1 Kits ELISA) to exert role in DNA interstrand crosslink repair; Usp1 (Montrer USP1 Kits ELISA) role is de-ubiquitination of Pcna and Fancd2 (Fanconi anemia complementation group D2 (Montrer FANCD2 Kits ELISA)).

  6. The aberrant DNA replication mediated by the PCNA-DNA pol-beta (Montrer POLB Kits ELISA) complex induces p53 (Montrer TP53 Kits ELISA)-dependent neuronal cell death

  7. Demonstrate that miR (Montrer MLXIP Kits ELISA)-376a regulates primordial follicle assembly by modulating the expression of Pcna.

  8. while interaction with PCNA was important for targeting p21 to the CRL4Cdt2 ligase re-localized to MVM replication centers

  9. Styrax japonica glycoprotein increased diethylnitrosamine-induced PCNA activity.

  10. This study identifies a critical role for PCNA in adipose tissue development, and for the first time identifies a role of the core DNA replication machinery at the interface between proliferation and differentiation.

Zebrafish Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. The expression of telomerase activity and TERT (Montrer TERT Kits ELISA) in retina implies that telomerase has functions other than the elongation of telomere. These findings could provide new insights on telomerase function in the nervous system.

  2. intestinal clock controls the expression of key cell cycle regulators, such as cdc2 (Montrer CDK1 Kits ELISA), wee1 (Montrer WEE1 Kits ELISA), p21 (Montrer CDKN1A Kits ELISA), PCNA and cdk2 (Montrer CDK2 Kits ELISA), but only weakly influences cyclin B1 (Montrer CCNB1 Kits ELISA), cyclin B2 (Montrer CCNB2 Kits ELISA) and cyclin E1 (Montrer CCNE1 Kits ELISA) expression.

Pig (Porcine) Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. There is a link between the intestinal detoxification system (CYP1A) & cell renewal system (PCNA). These two processes are inversely correlated in beta-naphthoflavone- exposed fish

Xenopus laevis Proliferating Cell Nuclear Antigen (PCNA) interaction partners

  1. residue in PCNA that is essential to support destruction of all CRL4(Cdt2) substrates

  2. CRL4Cdt2 ubiquitin ligase directly associates with pcna through its C-terminal domain.

  3. PCNA monoubiquitylation serves as a molecular gas pedal that controls the speed of replisome movement during S phase.

  4. Immunodepletion of Swift PAX-interacting protein 1 (Montrer PAXIP1 Kits ELISA) from Xenopus extracts prevented efficient PCNA ubiquitination

  5. PCNA docking activates the pre-formed Cdt1-Cul4(DDB1) ligase complex. Thus, PCNA functions as a platform for Cdt1 destruction, ensuring efficient and temporally restricted inactivation of a key cell-cycle regulator.

PCNA profil antigène

Antigen Summary

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Alternative names and synonyms associated with PCNA

  • mutagen-sensitive 209 (mus209) Elisa Kit
  • proliferating cell nuclear antigen (pcna) Elisa Kit
  • proliferating cell nuclear antigen (pcnA) Elisa Kit
  • proliferating cell nuclear antigen (ANI_1_512014) Elisa Kit
  • proliferating cell nuclear antigen (AOR_1_1500154) Elisa Kit
  • proliferating cell nuclear antigen (PCNA) Elisa Kit
  • proliferating cell nuclear antigen (Pcna) Elisa Kit
  • Proliferating cell nuclear antigen-like (MGC53867) Elisa Kit
  • proliferating cell nuclear antigen-like (LOC100339381) Elisa Kit
  • proliferating cell nuclear antigen1 (pcna1) Elisa Kit
  • 53/13 Elisa Kit
  • AO090003000846 Elisa Kit
  • cb16 Elisa Kit
  • CG9193 Elisa Kit
  • Dmel\\CG9193 Elisa Kit
  • DmPCNA Elisa Kit
  • dPCNA Elisa Kit
  • fb36g03 Elisa Kit
  • l(2)02448 Elisa Kit
  • l(2)56F Elisa Kit
  • l(2)56Fa Elisa Kit
  • l(2)s1534 Elisa Kit
  • Mus209 Elisa Kit
  • pcna Elisa Kit
  • pcna-A Elisa Kit
  • Pcna/cyclin Elisa Kit
  • PCNA/mus209 Elisa Kit
  • PCNAR Elisa Kit
  • wu:fa28e03 Elisa Kit
  • wu:fb36g03 Elisa Kit

Protein level used designations for PCNA

CG9193-PA , CG9193-PB , Proliferating-cell-nuclear-antigen , mus209-PA , mus209-PB , proliferating cell nuclear antigen , proliferating-cell nuclear antigen , DNA polymerase delta auxiliary protein , cyclin , etID36690.10 , fa28e03 , proliferating cell nuclear antigen subtype1 , proliferating cell nuclear antigen subtype2 , proliferating cell nuclear antigen subtype3 , CL1137_1 , CL1137_1(454) , CL1137_1_ov , proliferative cell nuclear antigen

GENE ID SPECIES
37290 Drosophila melanogaster
544248 Solanum lycopersicum
857128 Guillardia theta
2761382 Methanococcus maripaludis S2
4978203 Aspergillus niger CBS 513.88
5788447 Bigelowiella natans
5991960 Aspergillus oryzae RIB40
10447350 Cryptomonas paramecium
5111 Homo sapiens
18538 Mus musculus
25737 Rattus norvegicus
30678 Danio rerio
477166 Canis lupus familiaris
515499 Bos taurus
373984 Gallus gallus
692192 Sus scrofa
100713865 Cavia porcellus
443155 Ovis aries
692356 Bombyx mori
394328 Xenopus laevis
100689335 Cricetulus griseus
398425 Xenopus laevis
100339381 Oryctolagus cuniculus
542425 Zea mays
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