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anti-Human LHX2 Anticorps:
anti-Rat (Rattus) LHX2 Anticorps:
anti-Mouse (Murine) LHX2 Anticorps:
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Human Monoclonal LHX2 Primary Antibody pour WB - ABIN659167
Cirulli, Kasperaviciūte, Attix, Need, Ge, Gibson, Goldstein: Common genetic variation and performance on standardized cognitive tests. dans European journal of human genetics : EJHG 2010
Show all 4 references for 659167
Human Monoclonal LHX2 Primary Antibody pour ICC, ELISA - ABIN969259
Mangale, Hirokawa, Satyaki, Gokulchandran, Chikbire, Subramanian, Shetty, Martynoga, Paul, Mai, Li, Flanagan, Tole, Monuki: Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate. dans Science (New York, N.Y.) 2008
Cow (Bovine) Polyclonal LHX2 Primary Antibody pour WB - ABIN2792632
Glenn, Maurer: MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression. dans The Journal of biological chemistry 2000
Goat Polyclonal LHX2 Primary Antibody pour IF (p), IHC (p) - ABIN1387858
Geng, Wang, Wang, Chen: Cyclic expression of Lhx2 is involved in secondary hair follicle development in cashmere goat. dans Gene expression patterns : GEP 2014
Findings demonstrate that miR (Montrer MLXIP Anticorps)-1238 inhibit the proliferation of NSCLC cells at least partly via repression of LHX2, shedding light on the mechanistic interaction of miR (Montrer MLXIP Anticorps)-1238 and LHX2 in NSCLC carcinogenesis.
Results show that LHX2 is overexpressed in pancreatic ductal adenocarcinoma cells and is involved in promoting cancer cell proliferation and enhanced tumor development.
Lhx2 directly regulates tanycyte specification and differentiation in the hypothalamus.
This study demonistrated that LHx2 regulates the development of the forebrain hem system.
The data indicate a dual role of Lhx2 during EMT (Montrer ITK Anticorps) and tumor progression: by inducing the expression of PDGF-B (Montrer PDGFB Anticorps), Lhx2 provokes an autocrine PDGF-B (Montrer PDGFB Anticorps)/PDGFRbeta loop required for cell migration, invasion and metastatic dissemination
The findings indicate that LHX2 regulates the transcription of downstream intrinsic and extrinsic molecules that are essential for early neural differentiation.
These results suggest that if LHX2 is involved in pituitary hormone (Montrer CGA Anticorps) deficiency associated with posterior pituitary and ocular defects, it would be a rare cause of this disease condition.
Mutations in LHX2 do not represent a frequent cause of micro/anophthalmia.
A large cohort of patients with schizencephaly, some with features of septo-optic dysplasia, were sequenced for mutations in LHX2, HESX1 (Montrer HESX1 Anticorps) and SOX2 (Montrer SOX2 Anticorps).
Lhx2 expression during porcine fetal and postnatal pituitary development showed a gradual increase from fetal day (f) 40 to postnatal day (p) 8 followed by a slight decrease to p230 (Montrer TNC Anticorps).
Lack of Lhx2/Lhx9 (Montrer LHX9 Anticorps) function as well as increased Wnt (Montrer WNT2 Anticorps) signaling alter the expression of the thalamus specific cell adhesion factor pcdh10b and lead subsequently to a striking anterior-posterior disorganization of the caudal (Montrer CAD Anticorps) forebrain.
Lhx2 may mediate an alternative or parallel pathway for control of cellular proliferation in the developing forebrain via Six3.
Neuroretinal expression of Lhx2 and neuroretina-derived FGF factors are crucial for lens fiber development in vivo.
LHX2 is a key component of the control network for producing neurons that will participate in cortical circuitry
We found that expression of Emx2 (Montrer EMX2 Anticorps) and Lhx2 initiated between neuronal progenitor and neuronal precursor stages. As far as the sensory neurons of the vomeronasal organ are concerned, Meis1 (Montrer MEIS1 Anticorps) and Meis2 (Montrer MEIS2 Anticorps) were only expressed in the apical layer, together with Gnai2 (Montrer GNAI2 Anticorps), but not in the basal layer.
Lhx2 is required for maintenance of the corneal epithelial cell compartment and the limbal barrier.
The ectopic expression of Lhx2 in OP9 cells (OP9-Lhx2) accelerates the hematopoietic differentiation of PSCs.
Conditional knock-out of Lhx2 resulted in down-regulation of Notch (Montrer NOTCH1 Anticorps) pathway genes in retinal glia.
These studies define essential roles for Lhx2 in glial wedge, hippocampal commissure, and corpus callosum formation, and suggest that defects in radial glial wedge progenitors can give rise to corpus callosum.
CTIP2 (Montrer BCL11B Anticorps) transcription factor maintains stem cells in hair follicle and alters LHX2 expression.
Lhx2 regulates the timing of beta-catenin (Montrer CTNNB1 Anticorps)-dependent cortical neurogenesis.
Lhx2 controls neocortical area patterning by regulating downstream genetic and epigenetic regulators that drive the acquisition of molecular properties in cortical plate neurons.
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution.
LIM homeobox protein 2
, LIM homeodomain
, LIM/homeobox protein Lhx2
, LIM HOX gene 2
, homeobox protein LH-2
, LIM homeobox 2
, LIM homeodomain type transcription factor Lhx2
, LIM homeo box protein 2