Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
Afficher toutes les espèces
Afficher tous les synonymes
Sélectionnez vos espèces et l'application
anti-Human STK3 Anticorps:
anti-Mouse (Murine) STK3 Anticorps:
anti-Rat (Rattus) STK3 Anticorps:
Vous arrivez à notre recherche pré-filtrée.
These findings reveal a novel layer of regulation for MST2 in mitosis and its role in tumorigenesis.
TNFAIP8 (Montrer TNFAIP8 Anticorps) regulates Hippo (MST1 (Montrer MST1 Anticorps)/2) signaling through its interaction with LATS1 (Montrer LATS1 Anticorps).
Data suggest that Hippo (MST1 (Montrer MST1 Anticorps)/2 protein kinases) - Yes associated protein 1 (YAP (Montrer YAP1 Anticorps)) pathway involved in carcinogenesis of pancreatic cancer and in the inhibition effect of stiehopus japonieus acidic mucopolysaccharide (SJAMP) to the proliferation of pancreatic cancer cell.
H-ras (Montrer HRAS Anticorps), via an Erk (Montrer EPHB2 Anticorps)-dependent mechanism, downregulates Mst1 (Montrer MST1 Anticorps)/Mst2 activity by inducing the formation of inactive Mst1 (Montrer MST1 Anticorps)/Mst2 heterodimers.
Results show that STK3 is targeted by Casp6 (Montrer CASP6 Anticorps) and demonstrate that alterations in STK3 protein expression levels and post-translational modifications are detected in a cellular model of HD and caspase (Montrer CASP3 Anticorps)-mediated generation of STK3 fragments observed under conditions of stress in cells expressing mhtt.
using an Mst2 mutation that disrupts homotypic dimerization, we showed that the monomeric Mst2-SARAH domain could form a stable complex of 1:1 stoichiometric ratio with WW45 (Montrer SAV1 Anticorps) refolded under acidic pH.
The MST1/2-SAV1 complex, a core component of the Hippo pathway, promotes ciliogenesis.
These results suggest that AIF (Montrer AIFM1 Anticorps) downregulation is a common event in kidney tumor development. AIF (Montrer AIFM1 Anticorps) loss may lead to decreased STK3 activity, defective apoptosis and malignant transformation
Hippo and Yap (Montrer YAP1 Anticorps) regulate cardiomyocyte death and regeneration.
results reveal a novel role of Mst2 in stress-dependent cardiac hypertrophy and remodeling in the adult mouse and likely human heart
It is involved in apoptosis and serine/threonine kinase 3 (STK3 (Montrer PKN1 Anticorps)) is a recently identified caspase-6 (Montrer CASP6 Anticorps) substrate.
Using a standard two-thirds partial hepatectomy (PH) model in young and aged mice, the activity of the core kinases MST1 (Montrer MST1 Anticorps) and LATS1 (Montrer LATS1 Anticorps) increased during the early hypertrophic phase and returned to steady state levels in the proliferative phase, coinciding with activation of YAP1 (Montrer YAP1 Anticorps) target genes and hepatocyte proliferation.
Studies indicate that Hippo (Hpo (Montrer GFER Anticorps); MST1 (Montrer MST1 Anticorps)/2 in mammals) signaling pathway plays a central role in the cell fate-specification process.
Mst2 is involved in bone homeostasis, functioning as a reciprocal regulator of osteoclast and osteoblast differentiation through the NF-kappaB (Montrer NFKB1 Anticorps) pathway
the TLR-Mst1 (Montrer MST1 Anticorps)-Mst2-Rac (Montrer AKT1 Anticorps) signaling axis is critical for effective phagosome-mitochondrion function and bactericidal activity
These data indicate that that inhibition of mammalian sterile 20-like kinase 1 (Montrer STK4 Anticorps) rescued cardiac fibrosis and myocardial dysfunction in chronic beta1-adrenergic receptor stimulation-induced cardiomyopathy
Phosphorylation of LC3 (Montrer MAP1LC3A Anticorps) by the STK3 (Montrer PKN1 Anticorps) and STK4 is essential for autophagy.
These results identify MST2, not MST1 (Montrer MST1 Anticorps), as a critical regulator of caspase (Montrer CASP3 Anticorps)-mediated photoreceptor cell death in the detached retina and indicate its potential as a future neuroprotection target.
Mst1 (Montrer MST1 Anticorps)/2 regulate placental development by control of trophoblast cell differentiation and labyrinthine vasculature at midgestation and Mst1 (Montrer MST1 Anticorps)/2 control labyrinth morphogenesis in trophoblast- and fetal endothelial-dependent manners.
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
, STE20-like kinase MST2
, mammalian STE20-like protein kinase 2
, serine/threonine kinase 3 (STE20 homolog, yeast)
, serine/threonine kinase 3 (Ste20, yeast homolog)
, serine/threonine-protein kinase 3
, serine/threonine-protein kinase Krs-1
, protein kinase homolog
, serine/threonine kinase 3 (STE20 homolog)