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The protein encoded by HPD is an enzyme in the catabolic pathway of tyrosine. De plus, nous expédions HPD Protéines (21) et HPD Kits (14) et beaucoup plus de produits pour cette protéine.
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Human Monoclonal HPD Primary Antibody pour ICC, FACS - ABIN438818
Dorrell, Abraham, Lanxon-Cookson, Canaday, Streeter, Grompe: Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers. dans Stem cell research 2009
The mutagenesis and structural simulation studies demonstrate the critical and unique role of each ligand in the function of HPPD, and which correlates with their respective co-ordination position.
4-hydroxyphenylpyruvate dioxygenase gene mutation is associated with Hawkinsinuria.
Glutamine375 has a critical role for 4-HPPD in orientating the tail and ensuring the conformation of the terminal alpha-helix of the enzyme to maintain the integrity of the active site for biocatalysis.
The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.
, 4-hydroxyphenylpyruvic acid oxidase
, p-hydroxyphenylpyruvic hydroxylase
, 4-hydroxyphenylpyruvic acid dioxygenase
, f Alloantigen
, f protein
, glyoxalase domain containing 3
, F liver antigen