anti-5'-3' Exoribonuclease 2 (XRN2) Anticorps

XRN2 shares similarity with the mouse Dhm1 and the yeast dhp1 gene. De plus, nous expédions XRN2 Kits (5) et XRN2 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
XRN2 22803 Q9H0D6
XRN2 24128 Q9DBR1
XRN2 362229  
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Top anti-XRN2 Anticorps sur anticorps-enligne.fr

Showing 10 out of 52 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Souris Inconjugué ELISA, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using XRN2 mAb against human XRN2 (AA: 398-547) recombinant protein. (Expected MW is 43.1 kDa) 0.1 mg Connectez-vous pour afficher 8 to 11 Days
$561.00
Détails
Humain Lapin Inconjugué WB XRN2 Antibody (N-term) (ABIN658280) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the XRN2 antibody detected the XRN2 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Souris Inconjugué ELISA, FACS, IHC, WB ELISA: XRN2 Antibody (7C5B10)  - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Immunohistochemistry: XRN2 Antibody (7C5B10)  - Analysis of paraffin-embedded colon cancer tissues using XRN2 mouse mAb with DAB staining. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$514.63
Détails
Humain Lapin Inconjugué ELISA, IHC, WB 100 μL Connectez-vous pour afficher 16 Days
$181.73
Détails
Poulet Lapin Inconjugué IHC, WB   200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, IHC, WB ABIN6274505 at 1/100 staining Mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. ABIN6274505 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué ELISA, ICC, IF, IHC, WB Western blot analysis on COS7 cell lysate using XRN2 Antibody,The lane on the left is treated with the antigen-specific peptide. ABIN6266816 at 1/100 staining human liver tissue sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué ELISA, IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), IP, WB Western Blot and Immunoprecipitation: XRN2 Antibody [ABIN252879] - Detection of Human XRN2 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti- XRN2 antibody ABIN252879 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. XRN2 was also immunoprecipitated by another rabbit anti-XRN2 antibody, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 seconds (A) and 10 seconds (B). Western Blot: XRN2 Antibody [ABIN2528791] - Detection of Mouse : Whole cell lysate (50 ug) from TCMK-1, 4T1, and CT26.WT cells. Antibodies: Affinity purified rabbit anti-XRN2 antibody used for WB at 0.4 ug/ml.Detection: Chemiluminescence with an exposure time of 3 minutes. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$556.31
Détails
Humain Souris Inconjugué Fig. 1. Figure 1:Black line: Control Antigen (100 ng)Purple line: Antigen (10ng) 100 μg Connectez-vous pour afficher 11 to 16 Days
$426.40
Détails

anti-XRN2 Anticorps mieux référencés

  1. Human Polyclonal XRN2 Primary Antibody pour ICC, IF - ABIN252879 : Barnhart, Moon, Emch, Wilusz, Wilusz: Changes in cellular mRNA stability, splicing, and polyadenylation through HuR protein sequestration by a cytoplasmic RNA virus. dans Cell reports 2013 (PubMed)

Plus d’anticorps contre XRN2 partenaires d’interaction

Human 5'-3' Exoribonuclease 2 (XRN2) interaction partners

  1. depletion of NKRF (Montrer NKRF Anticorps), XRN2 or DHX15 (Montrer DHX15 Anticorps) impairs an early pre-rRNA cleavage step.

  2. XRN2 is a novel regulator of EMT (Montrer ITK Anticorps) that contributes to the metastatic processes in lung cancer through a novel miRNA regulatory mechanism.

  3. XRN2 has a role in R-loop resolution, suppression of replication stress, and maintenance of genomic stability

  4. Chromatin immunoprecipitation experiments further show that IL-1 (Montrer IL1A Anticorps) stimulation leads to decrease in NKRF (Montrer NKRF Anticorps) aa 421-429 phosphorylation and dissociation of NELF-E (Montrer RDBP Anticorps) and XRN2 by concomitant resumption of transcription elongation of a synthetic reporter

  5. P-TEFb (Montrer CCNT1 Anticorps) regulates termination by promoting chromatin recruitment and activation of a cotranscriptional RNA processing enzyme, Xrn2.

  6. The results suggest that CARF (Montrer CDKN2AIP Anticorps) regulates early steps of pre-rRNA processing during ribosome biogenesis by controlling spatial distribution of XRN2 between the nucleoplasm and nucleolus.

  7. Kinetic competition between elongating pol II (Montrer Pol II Anticorps) and the Xrn2 exonuclease (Montrer EXO1 Anticorps) is integral to termination of transcription on most human genes.

  8. found that the 3' fragments of target pre-mRNA generated by ASO were almost completely degraded from their 5' ends by nuclear XRN2 after RNase H1 (Montrer RNASEH1 Anticorps)-mediated cleavage

  9. The restriction of JFH1 and H77D hepatitis C virus replication by Xrn2 is likely indirect in nature and possibly linked to cytopathic effects of these robustly replicating viruses.

  10. Xrn2 has a cytoplasmic, antiviral function against HCV that is counteracted by HCV's subversion of miR (Montrer MLXIP Anticorps)-122 to form a protective oligomeric complex at the 5' end of the viral genome.

Mouse (Murine) 5'-3' Exoribonuclease 2 (XRN2) interaction partners

  1. Nkx2-5 (Montrer NKX2-5 Anticorps) genetically interacts with Xrn2 because Nkx2-5 (Montrer NKX2-5 Anticorps)(+/-)Xrn2(+/-), but neither Nkx2-5 (Montrer NKX2-5 Anticorps)(+/-)nor Xrn2(+/-), newborns exhibited a defect in ventricular septum formation, suggesting that the association between Nkx2-5 (Montrer NKX2-5 Anticorps) and Xrn2 is essential for heart development.

  2. Genetic variants regulating Xrn2 expression in cis (Montrer CISH Anticorps) are determinants of spontaneous lung tumor susceptibility in mice and have genetic equivalents in lung cancer susceptibility in human beings.

Arabidopsis thaliana 5'-3' Exoribonuclease 2 (XRN2) interaction partners

  1. AtXRN2 has a role in ribosomal RNA processing.

  2. The nuclear exoribonucleases XRN2 and XRN3 the nucleotidase/phosphatase FIERY1 are endogenous posttranscriptional gene silencing suppressors.

XRN2 profil antigène

Profil protéine

This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene\; however, their full-length nature is not known.

Gene names and symbols associated with XRN2

  • 5'-3' exoribonuclease 2 (xrn2) anticorps
  • 5'-3' exoribonuclease 2 (XRN2) anticorps
  • 5'-3' exoribonuclease 2, putative (TA11675) anticorps
  • 5'-3' exoribonuclease 2 (LELG_04162) anticorps
  • 5'-3' exoribonuclease 2 (AOR_1_874194) anticorps
  • 5'-3' exoribonuclease 2 (PTRG_01514) anticorps
  • 5'-3' exoribonuclease 2 (PTRG_10866) anticorps
  • 5'-3' exoribonuclease 2 (Tsp_08094) anticorps
  • 5'-3' exoribonuclease 2 S homeolog (xrn2.S) anticorps
  • 5'-3' exoribonuclease 2 (Xrn2) anticorps
  • exoribonuclease 2 (XRN2) anticorps
  • AO090012000503 anticorps
  • AtXRN2 anticorps
  • DKFZp459J063 anticorps
  • exoribonuclease 2 anticorps
  • K16E1.2 anticorps
  • K16E1_2 anticorps
  • wu:fb38g12 anticorps
  • wu:fj53d06 anticorps
  • zgc:55717 anticorps

Protein level used designations for XRN2

5'-3' exoribonuclease 2 , 5'-3' exoribonuclease 2-like , DHP protein , Dhm1-like protein (mouse homolog) , protein Dhm1

GENE ID SPECIES
321940 Danio rerio
458131 Pan troglodytes
477133 Canis lupus familiaris
517417 Bos taurus
700934 Macaca mulatta
733834 Xenopus (Silurana) tropicalis
3861687 Theileria annulata strain Ankara
5231754 Lodderomyces elongisporus NRRL YB-4239
5987983 Aspergillus oryzae RIB40
6338441 Pyrenophora tritici-repentis Pt-1C-BFP
6349178 Pyrenophora tritici-repentis Pt-1C-BFP
10906655 Trichinella spiralis
100031372 Monodelphis domestica
100049102 Xenopus laevis
100050094 Equus caballus
100173960 Pongo abelii
100353161 Oryctolagus cuniculus
100388181 Callithrix jacchus
100468930 Ailuropoda melanoleuca
100517201 Sus scrofa
100593111 Nomascus leucogenys
22803 Homo sapiens
24128 Mus musculus
362229 Rattus norvegicus
421236 Gallus gallus
834261 Arabidopsis thaliana
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