Use your antibodies-online credentials, if available.
Il n’y a pas de produits dans votre liste de comparaison.
Votre panier est vide.
AKAP8 encodes a member of the A-kinase anchor protein family. De plus, nous expédions AKAP8 Protéines (4) et et beaucoup plus de produits pour cette protéine.
Showing 10 out of 101 products:
Human Polyclonal AKAP8 Primary Antibody pour FACS, ICC - ABIN4278933
Li, Kao, Garcia, Shabanowitz, Hunt, Qin, Phelan, Lazar: A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. dans Genes & development 2006
Mouse (Murine) Polyclonal AKAP8 Primary Antibody pour ELISA, WB - ABIN250209
Eide, Coghlan, Orstavik, Holsve, Solberg, Skâlhegg, Lamb, Langeberg, Fernandez, Scott, Jahnsen, Taskén: Molecular cloning, chromosomal localization, and cell cycle-dependent subcellular distribution of the A-kinase anchoring protein, AKAP95. dans Experimental cell research 1998
The PKA-binding domain of AKAP8 and the C-terminal domain of DPY30, also called Dpy-30 motif, are crucial for the interaction between these proteins. AKAP8 interacts with DPY30 and the RII alpha regulatory subunit of PKA both in the interphase and in mitotic cells. A single amino acid substitution in DPY30 L69D affects its dimerization and completely abolishes its interaction with AKAP8.
These results establish AKAP95 as a mostly positive regulator of pre-mRNA splicing and a possible integrator of transcription and splicing regulation.
Results suggest that ALK generated by alternative transcription Initiation induces chromatin structural changes and heterochromatinization through phosphorylation of AKAP8 in the nucleus.
Using a BioID proximity-based proteomic screen, we identify the nuclear pore complex protein TPR as a novel AKAP95 binding partner. We show interaction between AKAP95 and TPR in mitosis, and an AKAP95-dependent enrichment of TPR in the spindle microtubule area in metaphase, then later in the spindle midzone area.
Report expression of connexin 43 in ovarian cancer cells in G1/S phase.
The data indicate that AKAP95 is a novel nucleolus-associated protein with a regulatory role on rRNA production.
Gene dosage at 19p13.12, and AKAP8 and/or AKAP8L in particular, play an important role in modulation of head size and may contribute to autism risk.
These results suggest that AKAP8 is involved in the regulation of chromatin structural changes through nuclear tyrosine phosphorylation.
Ectopic AKAP95 stimulates expression of a chromosomal reporter gene in synergy with MLL1 or MLL2, whereas AKAP95 depletion impairs retinoic acid-mediated gene induction in embryonic stem cells
AMY-1 interacts with S-AKAP84 and this protein in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex.
role of AKAP95 in DNA replication by providing a scaffold for MCM2
AKAP95 is a potential carrier protein for active caspase 3 from the cytoplasm into the nuclei in apoptotic cells.
This study showed an increase in the level of global DNA methylation starting in oocytes with diameters around 60 microm, increases in histone h4, and decreases in AKAP95.
a specific role for A kinase-anchoring protein 95 in suppressing the expression of the gene encoding tumor necrosis factor-alpha, which involved phosphorylation of p105 (also known as Nfkb1) by PKA
This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.
A kinase (PRKA) anchor protein 8
, A-kinase anchor protein 8
, A-kinase anchor protein 8-like
, a-kinase anchor protein 8-like
, A-kinase anchor protein, 95kDa
, A kinase anchor protein 8
, A kinase anchor protein 95
, A-kinase anchor protein 95 kDa
, AKAP 95
, protein kinase A-anchoring protein 95