anti-ADAM Metallopeptidase Domain 15 (ADAM15) Anticorps

The protein encoded by ADAM15 is a member of the ADAM (a disintegrin and metalloproteinase) protein family. De plus, nous expédions ADAM15 Kits (16) et ADAM15 Protéines (13) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ADAM15 11490 O88839
ADAM15 8751 Q13444
ADAM15 57025 Q9QYV0
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Top anti-ADAM15 Anticorps sur anticorps-enligne.fr

Showing 10 out of 74 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-ADAM15 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human brain 100 μL 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL 11 to 14 Days
$551.83
Détails
Humain Souris PE FACS Profile of anti-ADAM15 reactivity on MCF-7 cells analyzed by flow cytometry. ADAM15 Antibody (APC), Mouse MAb, Flow cytometric analysis 100 Tests 14 to 16 Days
$313.82
Détails
Humain Lapin PE FACS Profile of anti-ADAM15 reactivity on MCF-7 cells analyzed by flow cytometry. ADAM15 Antibody (APC), Rabbit MAb, Flow cytometric analysis 100 Tests 14 to 16 Days
$313.82
Détails
Humain Souris Inconjugué FACS, ELISA 100 μL 14 to 16 Days
$247.82
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Anti-ADAM15 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN961131 concentration 10 ug/ml. Anti-ADAM15 antibody IHC staining of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN961131 concentration 10 ug/ml. 100 μL 11 to 14 Days
$727.83
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of ADAM15 using NIH-3T3 whole cell lysates 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human skeletal muscle , using ADAM15, antibody(10 μg/ml). WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 7.5% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Détails
Humain Lapin Inconjugué ELISA, WB 100 μL 11 to 14 Days
$419.83
Détails
Humain Souris FITC FACS 100 Tests 14 to 16 Days
$262.06
Détails

anti-ADAM15 Anticorps mieux référencés

  1. Human Monoclonal ADAM15 Primary Antibody pour CyTOF, FACS - ABIN4900519 : Ungerer, Doberstein, Bürger, Hardt, Boehncke, Böhm, Pfeilschifter, Dummer, Mihic-Probst, Gutwein: ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma. dans Biochemical and biophysical research communications 2010 (PubMed)
    Show all 3 Pubmed References

Plus d’anticorps contre ADAM15 partenaires d’interaction

Rabbit ADAM Metallopeptidase Domain 15 (ADAM15) interaction partners

  1. ADAM15 attenuates the progression of atherosclerosis; in contrast, a mutated form of ADAM15, created by ablation of the protease function, has no significant effect on atherosclerosis.

Mouse (Murine) ADAM Metallopeptidase Domain 15 (ADAM15) interaction partners

  1. findings indicated that silencing ADAM15 had antiinflammatory effects in FLSs and efficiently inhibited the development of CIA.

  2. the catalytic activity of ADAM15 is not crucial for its function in promoting pathological neovascularization in the mouse OIR model, most likely because of the very limited substrate repertoire of ADAM15.

  3. ADAM15 upregulation contributes to inflammatory lung injury by promoting endothelial hyperpermeability and neutrophil transmigration.

  4. A disintegrin and metalloproteinase 15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity.

  5. Adult Adam15(-/-) mice displayed an increase in bone volume and thickness with an increase in the number and activity of osteoblasts, whereas osteoclasts were apparently unaffected.

  6. ADAM15 has a role in pathological neovascularization in mice

  7. cytoplasmic domain of ADAM15v2 strongly interacts with Lck and plays an important role in T lymphocytes

  8. The accelerated development of murine osteoarthritis in ADAM15 deficiency and the proadhesive and cell survival-promoting in vitro effect of ADAM15 overexpression suggest a homeostatic role of ADAM15 in cartilage remodeling.

  9. observations suggest that a disintegrin and metalloproteinase (ADAM)-8,-9,-10,-12,-15,and -17 play an important role in mouse uterine tissue remodelling during the oestrous cycle

  10. found modest expression of ADAM15 in pericytes in normal retina and strong up-regulation of ADAM15 in retinal vascular endothelial cells in ischemic retina

  11. ADAM10 performs a dual role in cells, as a metalloprotease when it is membrane-bound, and as a potential signaling protein once cleaved by ADAM9/15 and the gamma-Secretase

Human ADAM Metallopeptidase Domain 15 (ADAM15) interaction partners

  1. ET-1 expression in the endothelial cells of diabetic foot ulcers is an important determinant of insulin resistance at the onset of disease and induces macrophages to produce NF-kappaB, which regulates inflammation. It is thought that ADAM 15 contributes to angiogenic effects as a means of stimulating endothelial cells

  2. The results of our study demonstrate that ADAM15 is strongly up regulated in a small but highly aggressive fraction of prostate cancers.

  3. Data show that ADAM9 silencing affected MMP2 and ADAM15 expression.

  4. ADAM15 promotes lung cancer cell invasion through directly targeting MMP9 activation.

  5. the results revealed an undescribed role of ADAM15 in the invasion of human bladder cancer and suggested that the ADAM15 catalytic domain may represent a viable therapeutic target in patients with advanced disease.

  6. present a tumor suppressive mechanism for ADAM15 exosomes and provide insight into the functional significance of exosomes that generate tumor-inhibitory factors

  7. these data suggest the potential role of miR147b in regulating endothelial barrier function by targeting ADAM15 expression.

  8. findings indicated that silencing ADAM15 had antiinflammatory effects in FLSs and efficiently inhibited the development of CIA.

  9. The severity of intrauterine adhesions positively correlates to the protein and transcript expression levels of ADAM-15 and ADAM-17 in uterine tissue.

  10. ADAM15 contributes to apoptosis resistance in rheumatoid arthritis synovial fibroblasts by activating the Src/FAK pathway upon FasL exposure.

  11. In conclusion, our data identified rhddADAM15 as a potent inhibitor of tumor growth and metastasis, making it a promising tool for use in anticancer treatment.

  12. ADAM15 acts as a negative regulator of TRIF-mediated NF-kappaB and IFN-beta reporter gene activity via TLR3 and TLR4 signaling.

  13. dispensable for cutaneous wound healing and B16F1 melanoma growth, but significantly contributes to metastasis formation

  14. Exosomes rich in ADAM15 display enhanced binding affinity for integrin alphavbeta3 in an RGD-dependent manner and suppress vitronectin- and fibronectin-induced cell adhesion, growth, and migration, as well as in vivo tumor growth.

  15. ADAM15 tail can transduce a percepted extracellular signal to enhance FAK and Src phosphorylation.

  16. Promoter methylation of ADAM15 was examined as well as the microsatellite instability status. Thirty-six percent of colorectal carcinomas displayed a reduced expression of ADAM15.

  17. gene expressions for ADAM8 and ADAM15 were notably lower in ascending aorta as compared with aortic dissection

  18. demonstrate the intrinsic promoter activity of ADAM15 in quiescent mesangial cells and show the involvement of Sp1 in its regulation

  19. the downregulation of ADAM15 plays an important role in melanoma progression and ADAM15 act as a tumorsuppressor in melanoma.

  20. The effects of ADAM15 on endothelial hyperpermeability and neutrophil transmigration are mediated by intracellular signalling involving Src and ERK1/2 activation.

ADAM15 profil antigène

Profil protéine

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with ADAM15

  • ADAM metallopeptidase domain 15 (ADAM15) anticorps
  • ADAM metallopeptidase domain 15 L homeolog (adam15.L) anticorps
  • ADAM metallopeptidase domain 15 (adam15) anticorps
  • a disintegrin and metallopeptidase domain 15 (metargidin) (Adam15) anticorps
  • ADAM metallopeptidase domain 15 (Adam15) anticorps
  • ADAM15 anticorps
  • MDC15 anticorps
  • metargidin anticorps
  • tMDCVI anticorps

Protein level used designations for ADAM15

ADAM metallopeptidase domain 15 , a disintegrin and metalloproteinase domain 15 , metalloproteinase ADAM15 , disintegrin and metalloproteinase domain-containing protein 15-like , AD56 , ADAM 15 , MDC-15 , a disintegrin and metalloprotease domain 15 (metargidin) , a disintegrin and metalloproteinase domain 15 (metargidin) , disintegrin and metalloprotease 15 , disintegrin and metalloproteinase domain-containing protein 15 , metalloprotease RGD disintegrin protein , metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15 , CRII-7 , a disintegrin and metallopeptidase domain 15 (metargidin) , metargidin , tMDC VI

GENE ID SPECIES
457354 Pan troglodytes
490434 Canis lupus familiaris
100101326 Xenopus laevis
100145641 Xenopus (Silurana) tropicalis
100339079 Oryctolagus cuniculus
100393011 Callithrix jacchus
100468507 Ailuropoda melanoleuca
11490 Mus musculus
8751 Homo sapiens
784605 Bos taurus
57025 Rattus norvegicus
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