ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 3 Protéines (ADAMTS3)

ADAMTS3 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. De plus, nous expédions ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 3 Anticorps (14) et ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 3 Kits (13) et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
ADAMTS3 9508 O15072
Rat ADAMTS3 ADAMTS3 305253  
Souris ADAMTS3 ADAMTS3 330119  
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Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Cellules d'insectes Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 70 Days
$13,984.89
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Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
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HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
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ADAMTS3 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,

Plus protéines pour ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 3 (ADAMTS3) partenaires d'interaction

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 3 (ADAMTS3) interaction partners

  1. Molecular cloning and in silico analysis identify potential transcription factor binding sites in the ADAMTS3 promoter region and show that SP1 (Montrer PSG1 Protéines) downregulated ADAMTS3 transcriptional activity in osteosarcoma cell lines. As consistent with the transcriptional activity, mRNA, and protein expression levels were also decreased by SP1 (Montrer PSG1 Protéines).

  2. Results corroborate the recent in vitro and murine data that suggest a close functional interaction between ADAMTS3 and CCBE1 (Montrer CCBE1 Protéines) in triggering VEGFR3 (Montrer FLT4 Protéines) signaling, a cornerstone for the differentiation and function of lymphatic endothelial cells.

  3. Findings suggest that these MMP16 (Montrer MMP16 Protéines) rs10090371, ADAMTS3 rs788935, TLL2 (Montrer TLL2 Protéines) rs10882807 and MMP9 (Montrer MMP9 Protéines) rs3918251 may be promising prognostic biomarkers for cutaneous melanoma specific survival (CMSS).

  4. The pregnancy loss rate seems to be affected by both ADAMTS-3 and ADAMTS-16.

  5. Data indicate that ADAMTS2 and 3 cleave the amino-propeptide of fibrillar collagens and regulate blood vessels homeostasis and lymphangiogenesis. [review]

  6. ADAMTS-2 (Montrer ADAMTS4 Protéines), -3, and -13 expression, but not that of ADAMTS-14, are increased in plaques causing AMI (Montrer CFD Protéines) compared those associated with stable angina.

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 3 (ADAMTS3) interaction partners

  1. ADAMTS-3 was identified as the protease that cleaves and inactivates Reelin in the cerebral cortex and hippocampus. ADAMTS-3 was expressed in the excitatory neurons of the embryonic and postnatal cerebral cortex and hippocampus.

  2. an ADAMTS3 knockout mouse (Adamts3(-/-)) model was created to determine in vivo the actual functions of ADAMTS3.

Profil protéine ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 3 (ADAMTS3)

Profil protéine

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues.

Gene names and symbols associated with ADAMTS3

  • ADAM metallopeptidase with thrombospondin type 1 motif 3 (ADAMTS3)
  • ADAM metallopeptidase with thrombospondin type 1, motif 3 (Adamts3)
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3 (Adamts3)
  • ADAM metallopeptidase with thrombospondin type 1 motif 3 (Adamts3)
  • 1100001H14Rik Protéine
  • 6330442E02Rik Protéine
  • ADAMTS-4 Protéine

Protein level used designations for ADAMTS3

A disintegrin and metalloproteinase with thrombospondin motifs 3 , ADAM-TS 3 , ADAM-TS3 , ADAMTS-3 , PC II-NP , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3 , procollagen II N-proteinase , procollagen II amino propeptide-processing enzyme , zinc metalloendopeptidase , ADAM metallopeptidase with thrombospondin type 1 motif, 3

GENE ID SPECIES
9508 Homo sapiens
305253 Rattus norvegicus
330119 Mus musculus
100728969 Cavia porcellus
534082 Bos taurus
428760 Gallus gallus
100524818 Sus scrofa
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