anti-ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18) Anticorps

ADAMTS18 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. De plus, nous expédions ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 Kits (21) et ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 Protéines (3) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ADAMTS18 208936 Q4VC17
ADAMTS18 170692 Q8TE60
ADAMTS18 361412  
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Top anti-ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 Anticorps sur anticorps-enligne.fr

Showing 10 out of 40 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-ADAMTS18 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>721_B cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué WB Western blot analysis of ADAMTS18 expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué FACS, IHC (p), WB Western blot analysis of ADAMTS18 Antibody (C-term) (ABIN652853) in mouse liver tissue lysates (35 µg/lane). ADAMTS18 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with ADAMTS18 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails
Humain Lapin Inconjugué WB Western Blot: ADAMTS18 Antibody [NBP1-57095] - 721_B cell lysate, concentration 0.2-1 ug/ml. 100 μL Connectez-vous pour afficher 8 to 11 Days
$485.88
Détails
Humain Lapin Inconjugué WB ADAMTS18 antibody used at 1 ug/ml to detect target protein. 50 μg Connectez-vous pour afficher 2 to 3 Days
$473.93
Détails
Humain Lapin Alkaline Phosphatase (AP) ELISA, WB   200 μL Connectez-vous pour afficher 7 to 9 Days
$1,013.83
Détails
Humain Lapin APC ELISA, WB   200 μL Connectez-vous pour afficher 7 to 9 Days
$1,013.83
Détails
Humain Lapin Biotin ELISA, WB   200 μL Connectez-vous pour afficher 7 to 9 Days
$1,013.83
Détails

ADAMTS18 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Mouse (Murine) ,


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anti-ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 Anticorps mieux référencés

  1. Human Polyclonal ADAMTS18 Primary Antibody pour FACS, IHC (p) - ABIN652853 : Zeng, Corcoran, Collins-Racie, Lavallie, Morris, Flannery: Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18. dans Biochimica et biophysica acta 2006 (PubMed)
    Show all 4 Pubmed References

Plus d’anticorps contre ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 partenaires d’interaction

Mouse (Murine) ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18) interaction partners

  1. The underlying molecular mechanisms could be attributed in part to the abnormal vascular remodeling, including deficiency of carotid body (glomus) and aberrant carotid basal lamina. These results indicate a novel function of ADAMTS18 in vascular remodeling and associated thrombus formation.

  2. Adamts18 deficiency enhances tumorigenesis and intestinal inflammation through elevated Wnt/beta-catenin and p38MAPK/ERK1/2 signaling and promotes colon cancer in a mouse model.

  3. these data demonstrate a thrombin (Montrer F2 Anticorps) cleavage site and confirm a short form of ADAMTS-18 presents in vivo.

  4. Adamts18 is expressed in the lens and retina in the developing murine eye.

Human ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18) interaction partners

  1. In summary, we demonstrate that ADAMTS18 silencing in breast cancer is significantly correlated with promoter CpG methylation. ADAMTS18 acts as an antagonist of AKT (Montrer AKT1 Anticorps) and NF-kappaB (Montrer NFKB1 Anticorps) signaling, further suppressing EMT (Montrer ITK Anticorps) and metastasis of breast cancer cells.

  2. This study showed that ADAMTS1 (Montrer ADAMTS1 Anticorps), 8, and 18 are highly expressed in GC and its nodal metastases, suggesting important roles of these proteases in carcinogenesis and lymphatic metastasis. The findings from the present study indicate that these proteases may be promising candidates for novel and alternative treatments in GC (gastric cancer)

  3. Studies suggest that ADAM metallopeptidase (Montrer ECEL1 Anticorps) with thrombospondin type 1 motif, 18 protein (ADAMTS-18) as a promising diagnostic and therapeutic target.

  4. Novel homozygous mutations in ADAMTS18 were identified, consisting of c.1067T>A [p.L356*] in the first proband, c.2159G>C [p.C720S] in the 2 affected brothers

  5. Results suggest that ADAMTS18 plays an essential role in early eye development and that mutations therein cause a distinct eye phenotype that is mainly characterized by microcornea and myopia.

  6. study reveals that mutations in the ADAMTS18 gene can cause a broad phenotypic spectrum of eye disorders and contribute to shed further light on the complexity of retinal diseases

  7. the study identified ADAMTS18 as the only gene carrying a homozygous protein altering mutation.

  8. ADAMTS18 mutations promote growth, migration, and metastasis in melanoma

  9. ADAMTS18 gene methylation in 3 types of cancers was significantly higher than normal tissues. No significant association was found between methylation status & TNM (Montrer ODZ1 Anticorps) staging. Epigenetic regulation of ADAMTS18 was associated with carcinogenesis.

  10. comparison of the effects of C-terminal truncation on the GAG-binding properties and aggrecanase (Montrer ADAMTS4 Anticorps) activity of ADAMTS-5 (Montrer ADAMTS5 Anticorps) relative to three other ADAMTS (Montrer ADAMTS13 Anticorps) family members, ADAMTS-9 (Montrer ADAMTS9 Anticorps), ADAMTS-16 (Montrer ADAMTS16 Anticorps) and ADAMTS-18

ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18) profil antigène

Profil protéine

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.

Gene names and symbols associated with ADAMTS18

  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18 (Adamts18) anticorps
  • ADAM metallopeptidase with thrombospondin type 1 motif 18 (ADAMTS18) anticorps
  • ADAM metallopeptidase with thrombospondin type 1 motif, 18 (Adamts18) anticorps
  • 9630038L21 anticorps
  • ADAMTS21 anticorps
  • E130314N14Rik anticorps
  • KNO2 anticorps
  • RGD1560118 anticorps

Protein level used designations for ADAMTS18

A disintegrin and metalloproteinase with thrombospondin motifs 18 , ADAM-TS 18 , ADAM-TS18 , ADAMTS-18 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 18 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 21 , disintegrin and metalloprotease-like protein , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18

GENE ID SPECIES
208936 Mus musculus
100858277 Gallus gallus
170692 Homo sapiens
518395 Bos taurus
361412 Rattus norvegicus
101118979 Ovis aries
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