ALX Homeobox 3 (ALX3) Kits ELISA

ALX3 encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. De plus, nous expédions ALX3 Anticorps (34) et ALX3 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
ALX3 257 O95076
ALX3 365900  
ALX3 11694 O70137
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Top ALX3 Kits ELISA sur anticorps-enligne.fr

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Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Connectez-vous pour afficher 11 to 18 Days
$810.17
Détails
Humain
  96 Tests Connectez-vous pour afficher 2 to 3 Days
$380.00
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Plus Kits ELISA pour ALX3 partenaires d'interaction

Human ALX Homeobox 3 (ALX3) interaction partners

  1. Genome scan using 250k Nsp1 array followed by exome and Sanger sequence analysis revealed a novel homozygous nonsense variant (c.604C>T, p.Gln202*) in the ALX3 gene resulting in frontorhiny in the family. This is the first mutation in the ALX3 gene, underlying frontorhiny, in Pakistani population.

  2. Exclusion of mutations in ALX3 gene in patients with the syndrome of frontonasal dysgenesis, callosal agenesis, basal encephalocele, and eye anomalies

  3. We report a novel Y214X mutation in ALX3 in frontorhiny.

  4. The lack of a chromosome 1-derived fragment of ALX3 in restriction landmark genomic scanning and virtual genome scans of neuroblastomas is attributable to hypermethylation.

  5. Chromatin immunoprecipitation assays indicated that Alx3 in mouse pancreatic islets occupies the promoter of the mouse insulin (Montrer INS Kits ELISA) genes.

  6. ALX3 is essential for normal facial development in humans and that deficiency causes a clinically recognizable phenotype, which we term frontorhiny.

  7. Rat Alx3 undergoes restrictive or permissive interactions with nuclear proteins that determine its binding to and transactivation from TAAT target sites selected in a cell-specific manner.

Mouse (Murine) ALX Homeobox 3 (ALX3) interaction partners

  1. Study shows that ALX3 deficiency provides a novel molecular mechanism for developmental defects arising from maternal hyperglycaemia.

  2. results indicate that Alx3 expression is enhanced by BMP-2 (Montrer BMP2 Kits ELISA) via the BMP receptors mediated-Smad (Montrer SMAD1 Kits ELISA) signaling and that Alx3 is a positive regulator of osteoblast differentiation induced by BMP-2 (Montrer BMP2 Kits ELISA)

  3. Glucose-stimulated expression of ALX3 in alpha cells provides a regulatory mechanism for the downregulation of glucagon (Montrer GCG Kits ELISA) gene expression by interfering with PAX6 (Montrer PAX6 Kits ELISA)-mediated transactivation on the glucagon (Montrer GCG Kits ELISA) G1 promoter element.

  4. Pdx1 (Montrer PDX1 Kits ELISA), USF1 (Montrer USF1 Kits ELISA) and USF2 (Montrer USF2 Kits ELISA) co-ordinately regulate Alx3 gene expression in pancreatic beta-cells.

  5. Alx3 promoter activity in mesenchymal and pancreatic cells is regulatd by USF transcription factors and Twist1 (Montrer TWIST1 Kits ELISA)

  6. ALX3 could be considered as a candidate gene for the etiopathogenesis of diabetes or its complications during embryonic or fetal development is discussed

  7. ALX3 participates in the regulation of the expression of essential genes for the function of pancreatic islets, and its deficiency alters the regulation of glucose homeostasis in vivo.

  8. Alx3-deficient mice exhibit folic acid-resistant craniofacial midline and neural tube closure defects.

ALX3 profil antigène

Antigen Summary

This gene encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. Preferential methylation of this gene's promoter is associated with advanced-stage neuroblastoma tumors.

Gene names and symbols associated with ALX Homeobox 3 (ALX3) Kits ELISA

  • ALX homeobox 3 (ALX3) anticorps
  • ALX homeobox 3 (Alx3) anticorps
  • aristaless-like homeobox 3 (Alx3) anticorps
  • ALX3 anticorps
  • FND1 anticorps

Protein level used designations for ALX Homeobox 3 (ALX3) Kits ELISA

ALX homeobox 3 , aristaless-like homeobox 3 , homeobox protein aristaless-like 3 , proline-rich transcription factor ALX3 , aristaless 3 , proline-rich transcription factor Alx3

GENE ID SPECIES
469416 Pan troglodytes
522085 Bos taurus
700927 Macaca mulatta
257 Homo sapiens
365900 Rattus norvegicus
11694 Mus musculus
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