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ATPAF1 encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase.
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Asthma was found to be associated with a cluster of SNPs and SNP haplotypes containing the ATPAF1 gene
Ca(2 (Montrer CA2 Protéines)+)-dependent interaction of SF100A1 with Atpaf1 leads to an increased ATP content in cardiomyocytes.
This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds specifically to the F1 beta subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly. Alternatively spliced transcript variants have been identified.
ATP synthase mitochondrial F1 complex assembly factor 1
, homolog of yeast ATP11