anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Anticorps

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits (28) et ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 259 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-ABCB1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  NCI-H226 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$319.00
Détails
Humain Souris Inconjugué IHC Immunohistochemistry: MDR1/ABCB1 Antibody (1A7) [NBP2-46466] - Analysis of Adenocarcinoma of Human breast tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min) Immunohistochemistry: MDR1/ABCB1 Antibody (1A7) [NBP2-46466] - Analysis of Carcinoma of Human pancreas tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$514.63
Détails
Humain Souris Inconjugué IHC, IHC (p) 100 μL Connectez-vous pour afficher 11 to 14 Days
$507.83
Détails
Humain Souris Inconjugué IHC, IHC (p), WB 100 μL Connectez-vous pour afficher 11 to 14 Days
$507.83
Détails
Humain Lapin Inconjugué ELISA, IHC, WB ABIN6268733 for IHC in human brain tissue Western blot analysis of MDR1 using HT-29 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Chien Lapin Inconjugué EIA, WB   0.1 mg Connectez-vous pour afficher 8 to 11 Days
$619.30
Détails
Humain Lapin Inconjugué ELISA, WB Western blot using  affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. Personal Communication, Anna Calcagno, CCR-NCI, Bethesda, MD. IHC using  ABCB1 Antibody at 20 ug/ml against FFPE human kidney. Moderate to strong cytoplasmic and membranous staining seen in this example. Similar staining also observed in other tissues including liver, kidney, and small intestine. The antibody showed minimal background staining and worked well in formalin-fixed tissues. Image provided courtesy of Lifespan Biosciences. 100 μg Connectez-vous pour afficher 5 to 7 Days
$583.50
Détails
Humain Lapin Inconjugué IHC, IHC (p) Immunohistochemistry: MDR1/ABCB1 Antibody [NBP1-90291] - Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. Immunohistochemistry-Paraffin: MDR1/ABCB1 Antibody  - Staining of human liver shows cytoplasmic positivity in hepatocytes. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$491.63
Détails
Humain Souris Inconjugué ICC, IHC (fro), IHC (p), WB   100 μg Connectez-vous pour afficher 4 to 6 Days
$280.00
Détails

anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Anticorps mieux référencés

  1. Human Polyclonal ABCB1 Primary Antibody pour IHC (fro), IHC (p) - ABIN3043967 : Gao, Liu, Wang, Lin, Zhang: Effects of Lewis Y antigen on the gene expression of multiple drug resistance-associated proteins in human ovarian cancer RMG-I-H cells. dans Medical oncology (Northwood, London, England) 2010 (PubMed)
    Show all 30 Pubmed References

  2. Human Polyclonal ABCB1 Primary Antibody pour ELISA, IHC - ABIN6263928 : Zhou, Lin, Zhang, Zhang, Zhang, Zhang, Xie, Ren: miR-506 enhances the sensitivity of human colorectal cancer cells to oxaliplatin by suppressing MDR1/P-gp expression. dans Cell proliferation 2017 (PubMed)
    Show all 4 Pubmed References

  3. Human Monoclonal ABCB1 Primary Antibody pour IHC (fro), FACS - ABIN2479419 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. dans Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 4 Pubmed References

  4. Human Monoclonal ABCB1 Primary Antibody pour FACS - ABIN2479421 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... dans Cancer research 1996 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal ABCB1 Primary Antibody pour FACS - ABIN2479422 : Koziolek, Riess, Geiger, Thévenod, Hauser: Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients. dans Kidney international 2001 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal ABCB1 Primary Antibody pour FACS - ABIN2479424 : Park, Lomri, Simeoni, Fruehauf, Mechetner: Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay. dans Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal ABCB1 Primary Antibody pour ELISA, WB - ABIN1724927 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. dans Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal ABCB1 Primary Antibody pour ELISA, WB - ABIN1724923 : Rubi?, Ho?ysz, Barczak, Gryczka, ?aci?ski, Jagielski, Czernikiewicz, Pó?rolniczak, Wojewoda, Perz, Bia?ek, Morze, Kandu?a, Lisiak, Mrozikiewicz, Grodecka-Gazdecka, Rybczy?ska: Study of ABCB1 polymorphism frequency in breast cancer patients from Poland. dans Pharmacological reports : PR 2013 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal ABCB1 Primary Antibody pour IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. dans Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 Pubmed References

  10. Human Monoclonal ABCB1 Primary Antibody pour ICC, IHC (fro) - ABIN3043101 : Wang, Deng, Lu, Xu, Yan, Ye, Chen et al.: Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 ... dans Basic & clinical pharmacology & toxicology 2012 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 partenaires d’interaction

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. MDR1 (Montrer TBC1D9 Anticorps) is not expressed on erythrocyte membrane.

  2. The genetic polymorphisms of the multi-drug resistance-1 (MDR-1 (Montrer TBC1D9 Anticorps)) and human cytochrome P450 (Montrer CYP Anticorps) 3A (CYP3A4 (Montrer CYP3A4 Anticorps) and CYP3A5 (Montrer CYP3A5 Anticorps)) genes were analyzed and compared between steroid sensitive, steroid resistant and control groups.

  3. This meta-analysis suggests that the MDR1 (Montrer TBC1D9 Anticorps) C > T polymorphism was not associated with the risk of MM. To confirm these findings, further comprehensive and well-designed studies are needed.

  4. High MDR1 (Montrer TBC1D9 Anticorps) expression is associated with chemoresistance in ovarian cancer.

  5. 13-cis (Montrer CISH Anticorps)-retinoic acid, retinol and retinyl-acetate inhibited the Pgp (Montrer PGPEP1 Anticorps) and ABCG2 mediated substrate transport as well as the substrate stimulated ATPase (Montrer DNAH8 Anticorps) activity of these transporters.

  6. Haplotype analysis of ABCB1 conducted in patients with bullous pemphigoid (Montrer DST Anticorps) demonstrated that the 1236T-2677G-3435T haplotype may protect against development of disease.

  7. High ABCB1 expression is associated with Bendamustine-resistance in Mantle Cell Lymphoma.

  8. Data show that multidrug resistance gene 1 (MDR1 (Montrer TBC1D9 Anticorps)) expression was associated with worsen survival of esophageal squamous cell carcinoma (ESCC) patients with cisplatin-based chemotherapy.

  9. ABCB1 variation affected myelosuppression, progression-free survival and overall survival in ovarian cancer patients who were treated with paclitaxel and carboplatin

  10. Our data showed that the expression of the MDR1 (Montrer TBC1D9 Anticorps) gene was significantly higher in malignant tissue than in the normal tissues of patients with STS (Montrer STS Anticorps). In addition, high MDR1 (Montrer TBC1D9 Anticorps) expression was significantly associated with local advances, as well as poor response to treatment.

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (Montrer ABCB4 Anticorps), Bcrp and Mrp1 (Montrer ABCC1 Anticorps) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. this study shows that MDR1 (Montrer ABCB4 Anticorps) deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation

  2. A panel of 18 P-gp (Montrer ABCB4 Anticorps) substrates were administered into the airways of an isolated perfused mouse lung (IPML) model derived from Mdr1a (Montrer ABCB4 Anticorps)/Mdr1b knockout mice. Parallel intestinal absorption studies were performed. Lung P-gp (Montrer ABCB4 Anticorps) can affect the pulmonary kinetics of a subset of P-gp (Montrer ABCB4 Anticorps) substrates.

  3. Data suggest that the overexpression of P-gp (Montrer ABCB4 Anticorps) in neoplastic cells may be associated with alterations in O-glycosylated cell surface proteins, including mucins, and this alteration may be responsible for the reduced cell sensitivity to the O-glycosylation inhibitor GalNAc-alpha-O-benzyl.

  4. We conclude that mdr1b and bcrp are essential to ovarian protection from chemotoxicity and may have an important physiological role in the ovary.

  5. Molecular Dynamics simulations and docking of drugs performed for P-gp (P-gp (Montrer ABCB4 Anticorps), multi-drug resistance protein, MDR1 (Montrer ABCB4 Anticorps)).Drugs with ER < 1 (Montrer MIER1 Anticorps) almost do not bind the main binding cavity (MBC (Montrer CACNA1C Anticorps)) of P-gp (Montrer ABCB4 Anticorps).

  6. conclusion, MDR1 (Montrer ABCB4 Anticorps) and BCRP are expressed on apical membranes of the rodent placental SynT (Montrer STX1A Anticorps)-II layer.

  7. Mdr1 (Montrer ABCB4 Anticorps) enforces T Cell homeostasis in the presence of intestinal bile acids.

  8. Loss of ABCB1 expression is associated with neonatal hyperbilirubinemia.

  9. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (Montrer ABCB4 Anticorps) ATPase (Montrer DNAH8 Anticorps) activity

  10. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) profil antigène

Profil protéine

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP binding cassette subfamily B member 1 (ABCB1) anticorps
  • ATP binding cassette subfamily B member 1A (Abcb1a) anticorps
  • ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) anticorps
  • ATP binding cassette subfamily B member 1 (Abcb1) anticorps
  • ABC20 anticorps
  • ABCB1 anticorps
  • CD243 anticorps
  • CLCS anticorps
  • GP170 anticorps
  • mdr anticorps
  • Mdr1 anticorps
  • Mdr1a anticorps
  • Mdr1b anticorps
  • p-gp anticorps
  • PGP1 anticorps
  • Pgy-1 anticorps
  • Pgy1 anticorps
  • xemdr anticorps

Protein level used designations for ABCB1

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , bovine P-glycoprotein , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B

GENE ID SPECIES
5243 Homo sapiens
170913 Rattus norvegicus
281585 Bos taurus
403879 Canis lupus familiaris
397812 Xenopus laevis
463516 Pan troglodytes
18669 Mus musculus
100682536 Cricetulus griseus
Fournisseurs de qualité sélectionnés pour anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Anticorps
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